{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T16:03:03Z","timestamp":1792857783517,"version":"4.5.0"},"reference-count":91,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100011102","name":"European Commission Seventh Framework Programme","doi-asserted-by":"publisher","award":["FP7\/2007-2013"],"award-info":[{"award-number":["FP7\/2007-2013"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"name":"DENFREE","award":["282378"],"award-info":[{"award-number":["282378"]}]},{"name":"The Portuguese Foundation for Science and Technology","award":["SFRH\/BD\/95626\/2013"],"award-info":[{"award-number":["SFRH\/BD\/95626\/2013"]}]},{"name":"FCT"},{"DOI":"10.13039\/501100008530","name":"FEDER","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100011929","name":"COMPETE","doi-asserted-by":"crossref","award":["PEst-C\/SAU\/LA0003\/2013"],"award-info":[{"award-number":["PEst-C\/SAU\/LA0003\/2013"]}],"id":[{"id":"10.13039\/501100011929","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.meegid.2018.04.018","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T21:42:31Z","timestamp":1523914951000},"page":"60-72","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Population genetics-informed meta-analysis in seven genes associated with risk to dengue fever disease"],"prefix":"10.1016","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3214-0759","authenticated-orcid":false,"given":"Marisa","family":"Oliveira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana P.","family":"Saraiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Cavadas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ver\u00f3nica","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Pedro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Casademont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Koeth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farida","family":"Alshamali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nourdin","family":"Harich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lotfi","family":"Cherni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Sierra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria G.","family":"Guzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anavaj","family":"Sakuntabhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2018.04.018_bb0005","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/nature11632","article-title":"An integrated map of genetic variation from 1,092 human genomes","volume":"491","author":"Abecasis","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.meegid.2018.04.018_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-800098-4.00001-5","article-title":"Revisiting dengue virus-host cell interaction: new insights into molecular and cellular virology","volume":"88","author":"Acosta","year":"2014","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.meegid.2018.04.018_bb0015","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.meegid.2013.04.024","article-title":"Association of promoter region polymorphisms of CD209 gene with clinical outcomes of dengue virus infection in Western India","volume":"17","author":"Alagarasu","year":"2013","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0020","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.meegid.2012.12.021","article-title":"Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection","volume":"14","author":"Alagarasu","year":"2013","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0025","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.humimm.2013.01.027","article-title":"Association of HLA-DRB1 and TNF genotypes with dengue hemorrhagic fever","volume":"74","author":"Alagarasu","year":"2013","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0030","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.humimm.2015.09.042","article-title":"Association of FCGR2A p.R131H and CCL2 c.-2518 A>G gene variants with thrombocytopenia in patients with dengue virus infection","volume":"76","author":"Alagarasu","year":"2015","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0035","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1093\/molbev\/msm277","article-title":"mtDNA variation predicts population size in humans and reveals a major southern Asian chapter in human prehistory","volume":"25","author":"Atkinson","year":"2008","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0040","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/nature15393","article-title":"A global reference for human genetic variation","volume":"526","author":"Auton","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.meegid.2018.04.018_bb0045","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","article-title":"Haploview: analysis and visualization of LD and haplotype maps","volume":"21","author":"Barrett","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1016\/j.meegid.2018.04.018_bb0050","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1101\/gr.154831.113","article-title":"Estimating and interpreting FST: the impact of rare variants","volume":"23","author":"Bhatia","year":"2013","journal-title":"Genome Res."},{"key":"10.1016\/j.meegid.2018.04.018_bb0055","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/nature12060","article-title":"The global distribution and burden of dengue","volume":"496","author":"Bhatt","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.meegid.2018.04.018_bb0060","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1099\/vir.0.82537-0","article-title":"Dengue virus (DENV) antibody-dependent enhancement of infection upregulates the production of anti-inflammatory cytokines, but suppresses anti-DENV free radical and pro-inflammatory cytokine production, in THP-1 cells","volume":"88","author":"Chareonsirisuthigul","year":"2007","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0065","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.micinf.2008.12.006","article-title":"Human genetic determinants of dengue virus susceptibility","volume":"11","author":"Coffey","year":"2009","journal-title":"Microbes Infect."},{"key":"10.1016\/j.meegid.2018.04.018_bb0070","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1038\/ng.3021","article-title":"Whole-genome sequence variation, population structure and demographic history of the Dutch population","volume":"46","author":"Consortium, T.G.o.t.N","year":"2014","journal-title":"Nat. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0075","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1038\/nature04226","article-title":"A haplotype map of the human genome","volume":"437","author":"Consortium, T.I.H","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.meegid.2018.04.018_bb0080","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/1471-2350-15-58","article-title":"A replication study confirms the association of GWAS-identified SNPs at MICB and PLCE1 in Thai patients with dengue shock syndrome","volume":"15","author":"Dang","year":"2014","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0085","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s12881-016-0305-3","article-title":"Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever","volume":"17","author":"Dang","year":"2016","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0090","doi-asserted-by":"crossref","first-page":"14688","DOI":"10.1073\/pnas.1508114112","article-title":"Asymptomatic humans transmit dengue virus to mosquitoes","volume":"112","author":"Duong","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.meegid.2018.04.018_bb0095","first-page":"47","article-title":"Arlequin (version 3.0): an integrated software package for population genetics data analysis","volume":"1","author":"Excoffier","year":"2005","journal-title":"Evol. Bioinformatics Online"},{"key":"10.1016\/j.meegid.2018.04.018_bb0100","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1399-0039.2004.00304.x","article-title":"TNF-alpha-308A allele, a possible severity risk factor of hemorrhagic manifestation in dengue fever patients","volume":"64","author":"Fernandez-Mestre","year":"2004","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.meegid.2018.04.018_bb0105","doi-asserted-by":"crossref","first-page":"157","DOI":"10.4103\/0974-777X.170501","article-title":"Polymorphisms of transporter associated with antigen presentation, tumor necrosis factor-alpha and Interleukin-10 and their implications for protection and susceptibility to severe forms of dengue fever in patients in Sri Lanka","volume":"7","author":"Fernando","year":"2015","journal-title":"J. Global Infect. Dis."},{"key":"10.1016\/j.meegid.2018.04.018_bb0110","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/nature11690","article-title":"Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants","volume":"493","author":"Fu","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.meegid.2018.04.018_bb0115","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.4269\/ajtmh.2010.09-0353","article-title":"Asymptomatic dengue infection in a Cuban population confirms the protective role of the RR variant of the FcgammaRIIa polymorphism","volume":"82","author":"Garcia","year":"2010","journal-title":"Am. J. Trop. Med. Hygiene"},{"key":"10.1016\/j.meegid.2018.04.018_bb0120","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.actatropica.2011.06.002","article-title":"Tumor necrosis factor alpha promoter polymorphisms in Mexican patients with dengue fever","volume":"120","author":"Garcia-Trejo","year":"2011","journal-title":"Acta Trop."},{"key":"10.1016\/j.meegid.2018.04.018_bb0125","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1093\/bioinformatics\/bts115","article-title":"rehh: an R package to detect footprints of selection in genome-wide SNP data from haplotype structure","volume":"28","author":"Gautier","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.meegid.2018.04.018_bb0130","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.tmaid.2015.12.004","article-title":"Dengue, chikungunya and Zika and mass gatherings: what happened in Brazil, 2014","volume":"14","author":"Gautret","year":"2016","journal-title":"Travel Med. Infect. Dis."},{"key":"10.1016\/j.meegid.2018.04.018_bb0135","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1159\/000360136","article-title":"The onset of lactase persistence in Europe","volume":"76","author":"Gerbault","year":"2013","journal-title":"Hum. Hered."},{"key":"10.1016\/j.meegid.2018.04.018_bb0140","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/GIM.0b013e3180676d79","article-title":"Non-replication of association studies: \"pseudo-failures\" to replicate?","volume":"9","author":"Gorroochurn","year":"2007","journal-title":"Genet. Med."},{"key":"10.1016\/j.meegid.2018.04.018_bb0145","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0140-6736(14)60572-9","article-title":"Dengue","volume":"385","author":"Guzman","year":"2015","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.meegid.2018.04.018_bb0150","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1126\/science.1243518","article-title":"A genetic atlas of human admixture history","volume":"343","author":"Hellenthal","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.meegid.2018.04.018_bb0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002397","article-title":"Genomic ancestry of north Africans supports back-to-Africa migrations","volume":"8","author":"Henn","year":"2012","journal-title":"PLoS Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0160","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/nrg3734","article-title":"Natural selection and infectious disease in human populations","volume":"15","author":"Karlsson","year":"2014","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0165","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1038\/ng.960","article-title":"Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1","volume":"43","author":"Khor","year":"2011","journal-title":"Nat. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0170","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.08347","article-title":"The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus","volume":"4","author":"Kraemer","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.meegid.2018.04.018_bb0175","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0161-5890(97)00052-7","article-title":"The \u2212308 tumor necrosis factor-alpha promoter polymorphism effects transcription","volume":"34","author":"Kroeger","year":"1997","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0180","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1126\/science.1153717","article-title":"Worldwide human relationships inferred from genome-wide patterns of variation","volume":"319","author":"Li","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.meegid.2018.04.018_bb0185","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/ng1071","article-title":"Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease","volume":"33","author":"Lohmueller","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0190","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/nature06611","article-title":"Proportionally more deleterious genetic variation in European than in African populations","volume":"451","author":"Lohmueller","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.meegid.2018.04.018_bb0195","doi-asserted-by":"crossref","first-page":"102","DOI":"10.4269\/ajtmh.2002.67.102","article-title":"Susceptibility to dengue hemorrhagic fever in Vietnam: evidence of an association with variation in the vitamin d receptor and Fc gamma receptor IIa genes","volume":"67","author":"Loke","year":"2002","journal-title":"Am. J. Trop. Med. Hygiene"},{"key":"10.1016\/j.meegid.2018.04.018_bb0200","doi-asserted-by":"crossref","first-page":"23698","DOI":"10.1074\/jbc.M504337200","article-title":"Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals","volume":"280","author":"Lozach","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.meegid.2018.04.018_bb0205","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ajhg.2013.06.020","article-title":"RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference","volume":"93","author":"Maples","year":"2013","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0210","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1004488","article-title":"Cuba: exploring the history of admixture and the genetic basis of pigmentation using autosomal and uniparental markers","volume":"10","author":"Marcheco-Teruel","year":"2014","journal-title":"PLoS Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0215","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/brb3.248","article-title":"Validation of a polygenic risk score for dementia in black and white individuals","volume":"4","author":"Marden","year":"2014","journal-title":"Brain Behav."},{"key":"10.1016\/j.meegid.2018.04.018_bb0220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003566","article-title":"High trans-ethnic replicability of GWAS results implies common causal variants","volume":"9","author":"Marigorta","year":"2013","journal-title":"PLoS Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0225","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1101\/gr.119636.110","article-title":"Human population dispersal \"Out of Africa\" estimated from linkage disequilibrium and allele frequencies of SNPs","volume":"21","author":"McEvoy","year":"2011","journal-title":"Genome Res."},{"key":"10.1016\/j.meegid.2018.04.018_bb0230","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.tim.2013.12.011","article-title":"Global spread of dengue virus types: mapping the 70 year history","volume":"22","author":"Messina","year":"2014","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0235","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1038\/sj.embor.embor851","article-title":"Neglected diseases: under-funded research and inadequate health interventions. Can we change this reality?","volume":"4","author":"Morel","year":"2003","journal-title":"EMBO Rep."},{"key":"10.1016\/j.meegid.2018.04.018_bb0240","doi-asserted-by":"crossref","first-page":"5170","DOI":"10.1182\/blood-2009-11-256479","article-title":"Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection","volume":"115","author":"Muntasell","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.meegid.2018.04.018_bb0245","first-page":"299","article-title":"Epidemiology of dengue: past, present and future prospects","volume":"5","author":"Murray","year":"2013","journal-title":"Clin. Epidemiol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0250","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/sj.embor.embor866","article-title":"Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses","volume":"4","author":"Navarro-Sanchez","year":"2003","journal-title":"EMBO Rep."},{"key":"10.1016\/j.meegid.2018.04.018_bb0255","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.actatropica.2014.05.021","article-title":"Contrasting associations of polymorphisms in FcgammaRIIa and DC-SIGN with the clinical presentation of dengue infection in a Mexican population","volume":"138","author":"Noecker","year":"2014","journal-title":"Acta Trop."},{"key":"10.1016\/j.meegid.2018.04.018_bb0260","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1007\/s00439-011-1124-4","article-title":"Consistency of genome-wide associations across major ancestral groups","volume":"131","author":"Ntzani","year":"2012","journal-title":"Hum. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0265","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1089\/vim.2013.0119","article-title":"Polymorphism of DC-SIGN (CD209) promoter in association with clinical symptoms of dengue fever","volume":"27","author":"Oliveira","year":"2014","journal-title":"Viral Immunol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0270","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006202","article-title":"Joint ancestry and association test indicate two distinct pathogenic pathways involved in classical dengue fever and dengue shock syndrome","volume":"12","author":"Oliveira","year":"2018","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.meegid.2018.04.018_bb0275","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/bioinformatics\/btg412","article-title":"APE: analyses of Phylogenetics and Evolution in R language","volume":"20","author":"Paradis","year":"2004","journal-title":"Bioinformatics"},{"key":"10.1016\/j.meegid.2018.04.018_bb0280","doi-asserted-by":"crossref","first-page":"18026","DOI":"10.1073\/pnas.1114759108","article-title":"Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants","volume":"108","author":"Park","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.meegid.2018.04.018_bb0285","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1007\/s00018-012-1149-4","article-title":"Multi-level regulation of cellular recognition of viral dsRNA","volume":"70","author":"Peisley","year":"2013","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.meegid.2018.04.018_bb0290","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.humimm.2010.08.004","article-title":"Tumor necrosis factor-alpha, transforming growth factor-beta1, and interleukin-10 gene polymorphisms: implication in protection or susceptibility to dengue hemorrhagic fever","volume":"71","author":"Perez","year":"2010","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0295","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/ng1847","article-title":"Principal components analysis corrects for stratification in genome-wide association studies","volume":"38","author":"Price","year":"2006","journal-title":"Nat. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0300","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1086\/321272","article-title":"Are rare variants responsible for susceptibility to complex diseases?","volume":"69","author":"Pritchard","year":"2001","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0305","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0080031","article-title":"The first modern human dispersals across Africa","volume":"8","author":"Rito","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2018.04.018_bb0310","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nrg2760","article-title":"Genome-wide association studies in diverse populations","volume":"11","author":"Rosenberg","year":"2010","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0315","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/nature01140","article-title":"Detecting recent positive selection in the human genome from haplotype structure","volume":"419","author":"Sabeti","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.meegid.2018.04.018_bb0320","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/ng1550","article-title":"A variant in the CD209 promoter is associated with severity of dengue disease","volume":"37","author":"Sakuntabhai","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0325","doi-asserted-by":"crossref","first-page":"177","DOI":"10.7150\/ijms.8988","article-title":"High producing tumor necrosis factor alpha gene alleles in protection against severe manifestations of dengue","volume":"12","author":"Sam","year":"2015","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.meegid.2018.04.018_bb0330","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1089\/vim.2017.0029","article-title":"Genetic polymorphisms of tumor necrosis factor alpha and susceptibility to dengue virus infection in a Mexican population","volume":"30","author":"Sanchez-Leyva","year":"2017","journal-title":"Viral Immunol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0335","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.apjtm.2017.10.009","article-title":"Association of TNFA (-308G\/A), IFNG (+874 A\/T) and IL-10 (-819 C\/T) polymorphisms with protection and susceptibility to dengue in Brazilian population","volume":"10","author":"Santos","year":"2017","journal-title":"Asian Pac J Trop Med"},{"key":"10.1016\/j.meegid.2018.04.018_bb0340","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1002325","article-title":"Joint ancestry and association testing in admixed individuals","volume":"7","author":"Shriner","year":"2011","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0345","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006220","article-title":"OSBPL10, RXRA and lipid metabolism confer African-ancestry protection against dengue haemorrhagic fever in admixed Cubans","volume":"13","author":"Sierra","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.meegid.2018.04.018_bb0350","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1038\/ejhg.2010.98","article-title":"Dengue hemorrhagic fever is associated with polymorphisms in JAK1","volume":"18","author":"Silva","year":"2010","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0355","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1093\/infdis\/jiv321","article-title":"High anti-dengue virus activity of the OAS gene family is associated with increased severity of dengue","volume":"212","author":"Simon-Loriere","year":"2015","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.meegid.2018.04.018_bb0360","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/ng.2896","article-title":"The deleterious mutation load is insensitive to recent population history","volume":"46","author":"Simons","year":"2014","journal-title":"Nat. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0365","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.ajhg.2009.05.001","article-title":"Correcting for purifying selection: an improved human mitochondrial molecular clock","volume":"84","author":"Soares","year":"2009","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0370","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1093\/molbev\/msr245","article-title":"The expansion of mtDNA Haplogroup L3 within and out of Africa","volume":"29","author":"Soares","year":"2012","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0375","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.actatropica.2014.02.017","article-title":"Deconstructing \"malaria\": West Africa as the next front for dengue fever surveillance and control","volume":"134","author":"Stoler","year":"2014","journal-title":"Acta Trop."},{"key":"10.1016\/j.meegid.2018.04.018_bb0380","series-title":"In Silico Transcriptional Regulation and Functional Analysis of Dengue Shock Syndrome Associated SNPs in PLCE1 and MICB Genes","first-page":"335","volume":"vol. 16","author":"Taqi","year":"2016"},{"key":"10.1016\/j.meegid.2018.04.018_bb0385","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1084\/jem.20021840","article-title":"DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells","volume":"197","author":"Tassaneetrithep","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.meegid.2018.04.018_bb0390","article-title":"Association of Single-Nucleotide Polymorphisms in immune-related genes with development of dengue hemorrhagic fever in a Mexican population","author":"Vargas-Castillo","year":"2017","journal-title":"Viral Immunol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0395","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1086\/315215","article-title":"Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity","volume":"181","author":"Vaughn","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.meegid.2018.04.018_bb0400","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v036.i03","article-title":"Conducting meta-analyses in R with the metafor package","volume":"36","author":"Viechtbauer","year":"2010","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.meegid.2018.04.018_bb0405","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0000934","article-title":"DC-SIGN (CD209) Promoter -336 A\/G polymorphism is associated with dengue hemorrhagic fever and correlated to DC-SIGN expression and immune augmentation","volume":"5","author":"Wang","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.meegid.2018.04.018_bb0410","doi-asserted-by":"crossref","first-page":"11822","DOI":"10.1128\/JVI.77.21.11822-11832.2003","article-title":"Dengue virus induces novel changes in gene expression of human umbilical vein endothelial cells","volume":"77","author":"Warke","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0415","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0059067","article-title":"Genetic variants of MICB and PLCE1 and associations with non-severe dengue","volume":"8","author":"Whitehorn","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2018.04.018_bb0420","series-title":"Dengue Haemorrhagic Fever: Diagnosis, Treatment, Prevention and Control","author":"WHO","year":"1997"},{"key":"10.1016\/j.meegid.2018.04.018_bb0425","series-title":"Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control","first-page":"160","author":"WHO","year":"2009"},{"key":"10.1016\/j.meegid.2018.04.018_bb0430","series-title":"Accelerating Work to Overcome the Global Impact of Neglected Tropical Diseases. A Roadmap for Implementation","author":"WHO","year":"2012"},{"key":"10.1016\/j.meegid.2018.04.018_bb0435","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ajhg.2012.12.005","article-title":"Deep whole-genome sequencing of 100 southeast Asian Malays","volume":"92","author":"Wong","year":"2013","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.meegid.2018.04.018_bb0440","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.meegid.2013.08.017","article-title":"Single nucleotide polymorphisms in candidate genes and dengue severity in children: a case-control, functional and meta-analysis study","volume":"20","author":"Xavier-Carvalho","year":"2013","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.meegid.2018.04.018_bb0445","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.meegid.2017.11.009","article-title":"Host genetics and dengue fever","volume":"56","author":"Xavier-Carvalho","year":"2017","journal-title":"Infect. Genet. Evol."},{"issue":"Suppl. 11","key":"10.1016\/j.meegid.2018.04.018_bb0450","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1186\/1471-2105-15-S11-S6","article-title":"Whole genome sequencing of 35 individuals provides insights into the genetic architecture of Korean population","volume":"15","author":"Zhang","year":"2014","journal-title":"BMC Bioinforma."},{"key":"10.1016\/j.meegid.2018.04.018_bb0455","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1086\/512821","article-title":"Overcoming the winner's curse: estimating penetrance parameters from case-control data","volume":"80","author":"Zollner","year":"2007","journal-title":"Am. J. Hum. Genet."}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134818301965?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134818301965?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T11:13:19Z","timestamp":1542625999000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134818301965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":91,"alternative-id":["S1567134818301965"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2018.04.018","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Population genetics-informed meta-analysis in seven genes associated with risk to dengue fever disease","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2018.04.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}