{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T14:40:40Z","timestamp":1793198440333,"version":"4.5.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100009997","name":"Earmarked Fund for Modern Agro-industry Technology Research System","doi-asserted-by":"publisher","award":["CARS-40"],"award-info":[{"award-number":["CARS-40"]}],"id":[{"id":"10.13039\/501100009997","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.meegid.2018.08.026","type":"journal-article","created":{"date-parts":[[2018,8,26]],"date-time":"2018-08-26T09:47:58Z","timestamp":1535276878000},"page":"392-398","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Emerging of a highly pathogenic and multi-drug resistant strain of Escherichia coli causing an outbreak of colibacillosis in chickens"],"prefix":"10.1016","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3773-2224","authenticated-orcid":false,"given":"Junfeng","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyan","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongqiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijun J.","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2018.08.026_bb0005","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1185\/03007995.2015.1018989","article-title":"Colistin, mechanisms and prevalence of resistance","volume":"31","author":"Bialvaei","year":"2015","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.meegid.2018.08.026_bb0010","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.bcp.2005.11.012","article-title":"Understanding the longevity of the beta-lactam antibiotics and of antibiotic\/beta-lactamase inhibitor combinations","volume":"71","author":"Buynak","year":"2006","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0015","doi-asserted-by":"crossref","first-page":"334","DOI":"10.3389\/fmicb.2014.00334","article-title":"Use of antibiotics as feed additives: a burning question","volume":"5","author":"Chattopadhyay","year":"2014","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0020","series-title":"Performance Standards for Antimicrobial Susceptibility Testing: Twenty-Fifth Informational Supplement","author":"Clinical and Laboratory Standards Institute","year":"2015"},{"key":"10.1016\/j.meegid.2018.08.026_bb0025","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00560-17","article-title":"Cooperative immune suppression by Escherichia coli and shigella effector proteins","volume":"86","author":"De Jong","year":"2018","journal-title":"Infect. Immun."},{"key":"10.1016\/j.meegid.2018.08.026_bb0030","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.vetmic.2013.06.013","article-title":"Antimicrobial resistance selection in avian pathogenic E. Coli during treatment","volume":"166","author":"Dheilly","year":"2013","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0035","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.gene.2015.10.012","article-title":"Characterization of avian pathogenic Escherichia coli isolated in eastern China","volume":"576","author":"Dou","year":"2016","journal-title":"Gene"},{"key":"10.1016\/j.meegid.2018.08.026_bb0040","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1128\/iai.60.7.2648-2656.1992","article-title":"Pap-and pil-related DNA sequences and other virulence determinants associated with Escherichia coli isolated from septicemic chickens and turkeys","volume":"60","author":"Dozois","year":"1992","journal-title":"Infect. Immun."},{"key":"10.1016\/j.meegid.2018.08.026_bb0045","first-page":"381","volume":"116","author":"Ewers","year":"2003","journal-title":"Berl. Munch. Tierarztl. Wochenschr."},{"key":"10.1016\/j.meegid.2018.08.026_bb0050","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ijmm.2007.01.003","article-title":"Avian pathogenic, uropathogenic, and newborn meningitis-causing Escherichia coli: how closely related are they?","volume":"297","author":"Ewers","year":"2007","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0055","first-page":"164","article-title":"The isolation and identification of pathogenic Escherichia coli isolates of chicken origin from some regions in China","volume":"30","author":"Gao","year":"1999","journal-title":"Chin. J. Anim. Vet. Sci."},{"key":"10.1016\/j.meegid.2018.08.026_bb0060","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/1471-2180-12-143","article-title":"Roles of iron acquisition systems in virulence of extraintestinal pathogenic Escherichia coli: salmochelin and aerobactin contribute more to virulence than heme in a chicken infection model","volume":"12","author":"Gao","year":"2012","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0065","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.vetmic.2014.04.019","article-title":"Advances in vaccination against avian pathogenic Escherichia coli respiratory disease: potentials and limitations","volume":"172","author":"Ghunaim","year":"2014","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0070","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1080\/03079450500179046","article-title":"Avian pathogenic Escherichia coli transmission from broiler breeders to their progeny in an integrated poultry production chain","volume":"34","author":"Giovanardi","year":"2005","journal-title":"Avian Pathol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0075","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/femsle\/fnv118","article-title":"Avian colibacillosis: still many black holes","volume":"362","author":"Guabiraba","year":"2015","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.meegid.2018.08.026_bb0080","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1128\/IAI.72.1.593-597.2004","article-title":"Autotransporter genes pic and tsh are associated with Escherichia coli strains that cause acute pyelonephritis and are expressed during urinary tract infection","volume":"72","author":"Heimer","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.meegid.2018.08.026_bb0085","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.vetmic.2016.04.021","article-title":"The serine protease autotransporter Tsh contributes to the virulence of Edwardsiella tarda","volume":"189","author":"Hu","year":"2016","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0090","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1128\/CMR.4.1.80","article-title":"Virulence factors in Escherichia coli urinary tract infection","volume":"4","author":"Johnson","year":"1991","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.meegid.2018.08.026_bb0095","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1086\/315217","article-title":"Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise","volume":"181","author":"Johnson","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.meegid.2018.08.026_bb0100","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1136\/vr.157.19.573","article-title":"Observations on salpingitis, peritonitis and salpingoperitonitis in a layer breeder flock","volume":"157","author":"Jordan","year":"2005","journal-title":"Vet. Rec."},{"key":"10.1016\/j.meegid.2018.08.026_bb0105","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1128\/IAI.01230-10","article-title":"Transcriptome analysis of avian pathogenic Escherichia coli O1 in chicken serum reveals adaptive responses to systemic infection","volume":"79","author":"Li","year":"2011","journal-title":"Infect. Immun."},{"key":"10.1016\/j.meegid.2018.08.026_bb0110","article-title":"Staphylococcus sciuri exfoliative toxin C (ExhC) is a necrosis-inducer for mammalian cells","volume":"6","author":"Li","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2018.08.026_bb0115","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1093\/cid\/cis502","article-title":"Food-borne origins of Escherichia coli causing extraintestinal infections","volume":"55","author":"Manges","year":"2012","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.meegid.2018.08.026_bb0120","first-page":"696","article-title":"Multiplex PCR assay for detection of virulence genes in avian pathogenic Escherichia coli","volume":"54","author":"Meng","year":"2014","journal-title":"Wei Sheng Wu Xue Bao"},{"key":"10.1016\/j.meegid.2018.08.026_bb0125","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3389\/fmicb.2017.00063","article-title":"Antimicrobial resistance and molecular epidemiology of ESBL-producing Escherichia coli isolated from outpatients in town hospitals of Shandong Province, China","volume":"8","author":"Miao","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0130","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1128\/iai.28.2.359-367.1980","article-title":"Plasmid-determined resistance to serum bactericidal activity: a major outer membrane protein, the traT gene product, is responsible for plasmid-specified serum resistance in Escherichia coli","volume":"28","author":"Moll","year":"1980","journal-title":"Infect. Immun."},{"key":"10.1016\/j.meegid.2018.08.026_bb0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000898","article-title":"The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65","volume":"6","author":"Newton","year":"2010","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.meegid.2018.08.026_bb0140","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.3382\/ps\/pew087","article-title":"Detection of virulence-associated genes in pathogenic and commensal avian Escherichia coli isolates","volume":"95","author":"Paixao","year":"2016","journal-title":"Poult. Sci."},{"key":"10.1016\/j.meegid.2018.08.026_bb0145","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.mib.2014.11.005","article-title":"Post-modern pathogens: surprising activities of translocated effectors from E. Coli and Legionella","volume":"23","author":"Pearson","year":"2015","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0150","article-title":"EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation","volume":"2","author":"Pearson","year":"2017","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0155","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1586\/eri.12.110","article-title":"Extraintestinal pathogenic Escherichia coli: an update on antimicrobial resistance, laboratory diagnosis and treatment","volume":"10","author":"Pitout","year":"2012","journal-title":"Expert Rev. Anti-Infect. Ther."},{"key":"10.1016\/j.meegid.2018.08.026_bb0160","doi-asserted-by":"crossref","first-page":"827","DOI":"10.4049\/jimmunol.148.3.827","article-title":"Role of TraT protein, an anticomplementary protein produced in Escherichia coli by R100 factor, in serum resistance","volume":"148","author":"Pramoonjago","year":"1992","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0165","doi-asserted-by":"crossref","first-page":"3547","DOI":"10.1128\/JB.186.11.3547-3560.2004","article-title":"The ETT2 gene cluster, encoding a second type III secretion system from Escherichia coli, is present in the majority of strains but has undergone widespread mutational attrition","volume":"186","author":"Ren","year":"2004","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0170","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1051\/vetres:2004057","article-title":"Characterizing the APEC pathotype","volume":"36","author":"Rodriguez-Siek","year":"2005","journal-title":"Vet. Res."},{"key":"10.1016\/j.meegid.2018.08.026_bb0175","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1637\/7195-041304R","article-title":"Serotyping and virulence genes detection in Escherichia coli isolated from fertile and infertile eggs, dead-in-shell embryos, and chickens with yolk sac infection","volume":"48","author":"Rosario","year":"2004","journal-title":"Avian Dis."},{"key":"10.1016\/j.meegid.2018.08.026_bb0180","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1128\/JCM.05057-11","article-title":"Diagnostic strategy for identifying avian pathogenic Escherichia coli based on four patterns of virulence genes","volume":"50","author":"Schouler","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0185","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1128\/AAC.43.8.2063","article-title":"Identification of functional amino acids in the macrolide 2\u2032-phosphotransferase II","volume":"43","author":"Taniguchi","year":"1999","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2018.08.026_bb0190","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1017\/S0950268816000820","article-title":"Escherichia coli type III secretion system 2 (ETT2) is widely distributed in avian pathogenic Escherichia coli isolates from Eastern China","volume":"144","author":"Wang","year":"2016","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.meegid.2018.08.026_bb0195","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.2307\/1591919","article-title":"Association of K-1 capsule, smooth lipopolysaccharides, traT gene, and Colicin V production with complement resistance and virulence of avian Escherichia coli","volume":"37","author":"Wooley","year":"1993","journal-title":"Avian Dis."},{"key":"10.1016\/j.meegid.2018.08.026_bb0200","doi-asserted-by":"crossref","first-page":"3483","DOI":"10.1128\/JCM.42.8.3483-3489.2004","article-title":"Characterization of multiple-antimicrobial-resistant Escherichia coli isolates from diseased chickens and swine in China","volume":"42","author":"Yang","year":"2004","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2018.08.026_bb0205","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1637\/10709-110113-ResNote.1","article-title":"A clinical survey of common avian infectious diseases in China","volume":"58","author":"Zhuang","year":"2014","journal-title":"Avian Dis."}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156713481830649X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156713481830649X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T14:35:15Z","timestamp":1761575715000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S156713481830649X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":41,"alternative-id":["S156713481830649X"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2018.08.026","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emerging of a highly pathogenic and multi-drug resistant strain of Escherichia coli causing an outbreak of colibacillosis in chickens","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2018.08.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}