{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T05:41:17Z","timestamp":1793425277334,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010203","name":"Agriculture Research System of China","doi-asserted-by":"publisher","award":["CARS-42-19"],"award-info":[{"award-number":["CARS-42-19"]}],"id":[{"id":"10.13039\/501100010203","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFD0501506"],"award-info":[{"award-number":["2018YFD0501506"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.meegid.2019.104017","type":"journal-article","created":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T01:54:24Z","timestamp":1566784464000},"page":"104017","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Pathogenicity of fowl adenovirus serotype 4 (FAdV-4) in chickens"],"prefix":"10.1016","volume":"75","author":[{"given":"Jie","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1793-0282","authenticated-orcid":false,"given":"Youxiang","family":"Diao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2019.104017_bb0005","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0034-5288(95)90005-5","article-title":"Hydropericardium syndrome in broiler chickens: its contagious nature and pathology","volume":"59","author":"Abdul-Aziz","year":"1995","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.meegid.2019.104017_bb0010","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1136\/vr.141.11.271","article-title":"Hydropericardium-hepatopathy syndrome in Asian poultry","volume":"141","author":"Asrani","year":"1997","journal-title":"Vet. Rec."},{"key":"10.1016\/j.meegid.2019.104017_bb0015","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1007\/s00705-012-1570-x","article-title":"Hydropericardium syndrome: current state and future developments","volume":"158","author":"Asthana","year":"2013","journal-title":"Arch. Virol."},{"key":"10.1016\/j.meegid.2019.104017_bb0020","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.3382\/ps.2012-02296","article-title":"Epidemiological investigation of outbreaks of fowl adenovirus infection in commercial chickens in Korea","volume":"91","author":"Choi","year":"2012","journal-title":"Poult. Sci."},{"key":"10.1016\/j.meegid.2019.104017_bb0025","doi-asserted-by":"crossref","first-page":"983","DOI":"10.3382\/ps.2010-01214","article-title":"Molecular characterization of fowl adenoviruses isolated from chickens with gizzard erosions","volume":"90","author":"Domanska-Blicharz","year":"2011","journal-title":"Poult. Sci."},{"key":"10.1016\/j.meegid.2019.104017_bb0030","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/2049-1891-5-4","article-title":"The influences of SE infection on layers' production performance, egg quality and blood biochemical indicators","volume":"5","author":"Fan","year":"2014","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.meegid.2019.104017_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1135(00)00288-1","article-title":"Nucleotide sequence of L1 and part of P1 of hexon gene of fowl adenovirus associated with hydropericardium hepatitis syndrome differs with the corresponding region of other fowl adenoviruses","volume":"78","author":"Ganesh","year":"2001","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.meegid.2019.104017_bb0040","series-title":"The Springer Index of Viruses","first-page":"13","article-title":"Aviadenovirus","author":"Harrach","year":"2011"},{"key":"10.1016\/j.meegid.2019.104017_bb0045","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1080\/03079450050045440","article-title":"Detection and differentiation of avian adenoviruses: a review","volume":"29","author":"Hess","year":"2000","journal-title":"Avian Pathol."},{"key":"10.1016\/j.meegid.2019.104017_bb0050","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0140-6736(99)00219-6","article-title":"Serum aminotransferase concentration as evidence of hepatocellular damage","volume":"355","author":"Kew","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.meegid.2019.104017_bb0055","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.meegid.2016.09.006","article-title":"Fowl adenovirus species C serotype 4 is attributed to the emergence of hepatitis-hydropericardium syndrome in chickens in China","volume":"45","author":"Li","year":"2016","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.meegid.2019.104017_bb0060","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1186\/s12917-018-1733-4","article-title":"Pathogenicity and molecular characterization of a fowl adenovirus 4 isolated from chicken associated with IBH and HPS in China","volume":"14","author":"Li","year":"2018","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.meegid.2019.104017_bb0065","series-title":"Fowl Adenovirus Serotype 4 SD0828 Infections Causes High Mortality Rate and Cytokine Levels in Specific Pathogen-Free Chickens Compared to Ducks","volume":"9","author":"Li","year":"2018"},{"key":"10.1016\/j.meegid.2019.104017_bb0070","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1177\/104063871002200207","article-title":"Characterization of Fowl adenovirus serotype 4 isolated from chickens with hydropericardium syndrome based on analysis of the short fiber protein gene","volume":"22","author":"Mase","year":"2010","journal-title":"J. Vet. Diagn. Investig."},{"key":"10.1016\/j.meegid.2019.104017_bb0075","doi-asserted-by":"crossref","first-page":"589","DOI":"10.20506\/rst.19.2.1238","article-title":"Avian adenoviruses","volume":"19","author":"McFerran","year":"2000","journal-title":"Rev. Sci. Tech."},{"key":"10.1016\/j.meegid.2019.104017_bb0080","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/s13337-013-0183-7","article-title":"Characterization of fowl adenoviruses associated with hydropericardium syndrome and inclusion body hepatitis in broiler chickens","volume":"25","author":"Mittal","year":"2014","journal-title":"Virusdisease"},{"key":"10.1016\/j.meegid.2019.104017_bb0085","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/s12917-017-1134-0","article-title":"Preparation and evaluation of goose reovirus inactivated vaccine","volume":"13","author":"Niu","year":"2017","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.meegid.2019.104017_bb0090","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/oxfordjournals.aje.a118408","article-title":"A simple method OF estimating fifty per cent endpoints","volume":"27","author":"Reed","year":"1938","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.meegid.2019.104017_bb0095","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.3382\/ps\/pez042","article-title":"Pathogenicity of a fowl adenovirus serotype 4 isolated from chickens associated with hydropericardium-hepatitis syndrome in China","volume":"98","author":"Ren","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.meegid.2019.104017_bb0100","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1093\/clinchem\/43.1.228","article-title":"Assessing liver function and hyperbilirubinemia in the newborn. National Academy of Clinical Biochemistry","volume":"43","author":"Rosenthal","year":"1997","journal-title":"Clin. Chem."},{"key":"10.1016\/j.meegid.2019.104017_bb0105","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/03079457.2017.1385724","article-title":"Fowl adenovirus-induced diseases and strategies for their control - a review on the current global situation","volume":"47","author":"Schachner","year":"2018","journal-title":"Avian Pathol."},{"key":"10.1016\/j.meegid.2019.104017_bb0110","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.vetimm.2007.09.017","article-title":"Fowl adenovirus (FAdV) serotype 4 causes depletion of B and T cells in lymphoid organs in specific pathogen-free chickens following experimental infection","volume":"121","author":"Schonewille","year":"2008","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.meegid.2019.104017_bb0115","series-title":"Classification of Fowl Adenovirus Serotypes by Use of High-Resolution Melting-Curve Analysis of the Hexon Gene Region","first-page":"311","volume":"47","author":"Steer","year":"2009"},{"key":"10.1016\/j.meegid.2019.104017_bb0120","first-page":"886","article-title":"Identification of 12 serotypes of aviadenovirus group I by PCR-RFLP assay","volume":"39","author":"Tang","year":"2009","journal-title":"Chin. Vet. Sci."},{"key":"10.1016\/j.meegid.2019.104017_bb0125","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1586\/erv.09.29","article-title":"Strategies to overcome host immunity to adenovirus vectors in vaccine development","volume":"8","author":"Thacker","year":"2009","journal-title":"Expert Rev. Vaccines"},{"key":"10.1016\/j.meegid.2019.104017_bb0130","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2307\/1592507","article-title":"Chicken anemia virus and fowl adenoviruses: association to induce the inclusion body hepatitis\/hydropericardium syndrome","volume":"44","author":"Toro","year":"2000","journal-title":"Avian Dis."},{"key":"10.1016\/j.meegid.2019.104017_bb0135","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/03079457.2015.1125443","article-title":"Clinicopathological characterization and genomic sequence differences observed in a highly virulent fowl Aviadenovirus serotype 4","volume":"45","author":"Vera-Hernandez","year":"2016","journal-title":"Avian Pathol."},{"key":"10.1016\/j.meegid.2019.104017_bb0140","doi-asserted-by":"crossref","DOI":"10.1038\/emi.2016.50","article-title":"Outbreaks of serotype 4 fowl adenovirus with novel genotype, China","volume":"5","author":"Ye","year":"2016","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.meegid.2019.104017_bb0145","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2018.02772","article-title":"Pathogenic, phylogenetic, and serological analysis of group I fowl adenovirus serotype 4 SDSX Isolated From Shandong, China","volume":"9","author":"Yu","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.meegid.2019.104017_bb0150","article-title":"Correction: pathogenicity and complete genome characterization of fowl adenoviruses isolated from chickens associated with inclusion body hepatitis and hydropericardium syndrome in China","volume":"11","author":"Zhao","year":"2016","journal-title":"PLoS One"}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134819302448?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134819302448?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T14:36:59Z","timestamp":1761575819000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134819302448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":30,"alternative-id":["S1567134819302448"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2019.104017","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pathogenicity of fowl adenovirus serotype 4 (FAdV-4) in chickens","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2019.104017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104017"}}