{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:18:54Z","timestamp":1784938734622,"version":"3.55.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010083","name":"Hunan Provincial Innovation Foundation for Postgraduate","doi-asserted-by":"publisher","award":["2017-451"],"award-info":[{"award-number":["2017-451"]}],"id":[{"id":"10.13039\/501100010083","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009377","name":"Education Department of Hunan Province","doi-asserted-by":"publisher","award":["17B245"],"award-info":[{"award-number":["17B245"]}],"id":[{"id":"10.13039\/100009377","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273322"],"award-info":[{"award-number":["81273322"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.meegid.2019.104049","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T19:58:01Z","timestamp":1571860681000},"page":"104049","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["A comparison of genotyping tool in Treponema pallidum: Review and meta-analysis"],"prefix":"10.1016","volume":"78","author":[{"given":"Bo","family":"Fu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huahua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feijun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangquan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tie","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjian","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changqing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longgu","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiebing","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2019.104049_bb0005","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S1286-4579(01)01513-1","article-title":"The endemic treponematoses","volume":"4","author":"Antal","year":"2002","journal-title":"Microbes Infect."},{"key":"10.1016\/j.meegid.2019.104049_bb0010","article-title":"Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster","volume":"2","author":"Arora","year":"2017","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0015","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1128\/JCM.00083-12","article-title":"Molecular subtyping of Treponema pallidum during a local syphilis epidemic in men who have sex with men in Melbourne, Australia","volume":"50","author":"Azzato","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0020","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1128\/IAI.01424-07","article-title":"A novel Treponema pallidum antigen, TP0136, is an outer membrane protein that binds human fibronectin","volume":"76","author":"Brinkman","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.meegid.2019.104049_bb0025","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1186\/s12879-015-1098-2","article-title":"High incidence of diagnosis with syphilis co-infection among men who have sex with men in an HIV cohort in Ontario, Canada","volume":"15","author":"Burchell","year":"2015","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.meegid.2019.104049_bb0030","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1128\/JCM.00287-08","article-title":"Molecular subtyping of Treponema pallidum subsp. pallidum in Lisbon, Portugal","volume":"47","author":"Castro","year":"2009","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001471","article-title":"Whole genome sequences of three Treponema pallidum ssp. pertenue strains: yaws and syphilis treponemes differ in less than 0.2% of the genome sequence","volume":"6","author":"\u010cejkov\u00e1","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0040","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1136\/sti.2009.036301","article-title":"Molecular epidemiology of syphilis in Scotland","volume":"85","author":"Cole","year":"2009","journal-title":"Sex. Transm. Infect."},{"key":"10.1016\/j.meegid.2019.104049_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0000690","article-title":"Secondary syphilis in cali, Colombia: new concepts in disease pathogenesis","volume":"4","author":"Cruz","year":"2010","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0050","doi-asserted-by":"crossref","first-page":"3674","DOI":"10.1128\/JCM.01195-12","article-title":"Molecular typing of Treponema pallidum: a 5-year surveillance in Shanghai, China","volume":"50","author":"Dai","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0055","doi-asserted-by":"crossref","first-page":"232","DOI":"10.3389\/fmicb.2016.00232","article-title":"The evolution of advanced molecular diagnostics for the detection and characterization of Mycoplasma pneumoniae","volume":"7","author":"Diaz","year":"2016","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0060","first-page":"105","article-title":"Molecular detection and subtyping of Treponema pallidum subsp. pallidum in clinical specimens","volume":"55","author":"Flasarova","year":"2006","journal-title":"Epidemiologie, mikrobiologie, imunologie"},{"key":"10.1016\/j.meegid.2019.104049_bb0065","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/OLQ.0000000000000465","article-title":"Treponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru","volume":"43","author":"Flores","year":"2016","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0070","doi-asserted-by":"crossref","first-page":"3802","DOI":"10.1128\/JCM.00128-08","article-title":"Molecular typing of treponema pallidum clinical strains from Lisbon, Portugal","volume":"46","author":"Florindo","year":"2008","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0075","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0172905","article-title":"Molecular typing of Treponema pallidum isolates from Buenos Aires, Argentina: frequent Nichols-like isolates and low levels of macrolide resistance","volume":"12","author":"Gallo Vaulet","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2019.104049_bb0080","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/OLQ.0000000000000741","volume":"45","author":"Giacani","year":"2018","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0085","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/OLQ.0000000000000006","article-title":"Molecular subtyping of Treponema pallidum in Paris, France","volume":"40","author":"Grange","year":"2013","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0090","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.1128\/JCM.01292-14","article-title":"Molecular typing of Treponema pallidum in the Czech Republic during 2011 to 2013: increased prevalence of identified genotypes and of isolates with macrolide resistance","volume":"52","author":"Grillova","year":"2014","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0200773","article-title":"Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme","volume":"13","author":"Grillova","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2019.104049_bb0100","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.6182","article-title":"A public database for the new MLST scheme for Treponema pallidum subsp. pallidum: surveillance and epidemiology of the causative agent of syphilis","volume":"6","author":"Grillova","year":"2019","journal-title":"PeerJ"},{"key":"10.1016\/j.meegid.2019.104049_bb0105","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1097\/OLQ.0b013e31826ae7a8","article-title":"Two mutations associated with macrolide resistance in Treponema pallidum: increasing prevalence and correlation with molecular strain type in Seattle, Washington","volume":"39","author":"Grimes","year":"2012","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0110","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1136\/bmj.328.7454.1490","article-title":"Grading quality of evidence and strength of recommendations","volume":"328","author":"Group","year":"2004","journal-title":"BMJ: British Medical Journal"},{"key":"10.1016\/j.meegid.2019.104049_bb0115","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1128\/jcm.26.11.2465-2466.1988","article-title":"Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity","volume":"26","author":"Hunter","year":"1988","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0120","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01167-18","article-title":"Molecular typing and macrolide resistance analyses of treponema pallidum in heterosexuals and men who have sex with men in Japan","volume":"57","author":"Kanai","year":"2019","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0125","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1097\/OLQ.0b013e3181e1a77a","article-title":"Molecular Epidemiology of Syphilis-San Francisco, 2004\u20132007","volume":"37","author":"Katz","year":"2010","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.meegid.2019.104049_bb0130","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/apm.12541","article-title":"Syphilis epidemiology in 1994-2013, molecular epidemiological strain typing and determination of macrolide resistance in Treponema pallidum in 2013-2014 in Tuva Republic, Russia","volume":"124","author":"Khairullin","year":"2016","journal-title":"Apmis"},{"key":"10.1016\/j.meegid.2019.104049_bb0135","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01148-18","article-title":"Circulation of distinct Treponema pallidum strains in individuals with heterosexual orientation and men who have sex with men","volume":"57","author":"Kojima","year":"2019","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0140","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3103\/S0891416817010098","article-title":"Molecular epidemiology of Treponema pallidum in a Frontier region of the Russian Federation (Tuva Republic)","volume":"32","author":"Kubanov","year":"2017","journal-title":"Molecular Genetics Microbiology and Virology"},{"key":"10.1016\/j.meegid.2019.104049_bb0145","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1086\/656533","article-title":"Enhanced molecular typing of treponema pallidum: geographical distribution of strain types and association with neurosyphilis","volume":"202","author":"Marra","year":"2010","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0150","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1086\/600878","article-title":"Macrolide resistance and molecular types of treponema pallidum causing primary syphilis in Shanghai, China","volume":"49","author":"Martin","year":"2009","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0155","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1097\/OLQ.0b013e3181d73ce1","article-title":"Molecular typing of Treponema pallidum strains in western Canada: predominance of 14d subtypes","volume":"37","author":"Martin","year":"2010","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0160","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/1471-2180-13-178","article-title":"Comparison of CDC and sequence-based molecular typing of syphilis treponemes: tpr and arp loci are variable in multiple samples from the same patient","volume":"13","author":"Mikalova","year":"2013","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0165","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1097\/OLQ.0000000000000600","article-title":"Molecular typing of Syphilis-causing strains among human immunodeficiency virus-positive patients in Antwerp, Belgium","volume":"44","author":"Mikalova","year":"2017","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0170","doi-asserted-by":"crossref","first-page":"264","DOI":"10.7326\/0003-4819-151-4-200908180-00135","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"151","author":"Moher","year":"2009","journal-title":"Ann. Int. Med."},{"key":"10.1016\/j.meegid.2019.104049_bb0175","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1136\/sti.2006.023895","article-title":"Molecular typing of Treponema pallidum strains from patients with neurosyphilis in Pretoria, South Africa","volume":"83","author":"Molepo","year":"2007","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.meegid.2019.104049_bb0180","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1136\/sextrans-2011-050322","article-title":"Macrolide resistance testing and molecular subtyping of Treponema pallidum strains from southern Africa","volume":"88","author":"Muller","year":"2012","journal-title":"Sex. Transm. Infect."},{"key":"10.1016\/j.meegid.2019.104049_bb0185","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1097\/OLQ.0000000000000440","article-title":"First Report of the 23S rRNA Gene A2058G Point Mutation Associated With Macrolide Resistance in Treponema pallidum From Syphilis Patients in Cuba","volume":"43","author":"Noda","year":"2016","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0190","article-title":"Molecular epidemiology of Staphylococcus aureus bacteremia in a single large Minnesota medical center in 2015 as assessed using MLST, core genome MLST and spa typing","volume":"12","author":"Park","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2019.104049_bb0195","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.3389\/fmicb.2018.01854","article-title":"Unveiling the Multilocus Sequence Typing (MLST) schemes and Core Genome phylogenies for genotyping Chlamydia trachomatis","volume":"9","author":"Pati\u00f1o","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0200","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001273","article-title":"Molecular typing of Treponema pallidum: a systematic review and meta-analysis","volume":"5","author":"Peng","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0205","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/OLQ.0b013e318232697d","article-title":"Molecular typing of Treponema pallidum causing early syphilis in China: a cross-sectional study","volume":"39","author":"Peng","year":"2012","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0210","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1586\/14787210.2015.990384","article-title":"Syphilis in the United States: on the rise?","volume":"13","author":"Peterman","year":"2015","journal-title":"Expert Rev. Anti-Infect. Ther."},{"key":"10.1016\/j.meegid.2019.104049_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0074319","article-title":"Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters","volume":"8","author":"P\u011btro\u0161ov\u00e1","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.meegid.2019.104049_bb0220","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/00007435-199809000-00004","article-title":"Molecular subtyping of Treponema pallidum subspecies pallidum","volume":"25","author":"Pillay","year":"1998","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0225","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1128\/JCM.40.1.256-258.2002","article-title":"Molecular typing of Treponema pallidum in South Africa: cross-sectional studies","volume":"40","author":"Pillay","year":"2002","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0230","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1128\/JCM.43.8.3743-3746.2005","article-title":"Molecular subtyping of Treponema pallidum from North and South Carolina","volume":"43","author":"Pope","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0235","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0201068","article-title":"Multi-locus sequence typing of Treponema pallidum subsp pallidum present in clinical samples from France: Infecting treponemes are genetically diverse and belong to 18 allelic profiles","volume":"13","author":"Pospisilova","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2019.104049_bb0240","series-title":"The Treponema Pallidum Outer Membrane, Spirochete Biology: The Post Genomic Era","first-page":"1","author":"Radolf","year":"2017"},{"key":"10.1016\/j.meegid.2019.104049_bb0245","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1128\/JCM.00959-16","article-title":"Treponema pallidum strain types and association with macrolide resistance in Sydney, Australia: new TP0548 gene types identified","volume":"54","author":"Read","year":"2016","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0250","doi-asserted-by":"crossref","first-page":"202","DOI":"10.2340\/00015555-2190","article-title":"Molecular Typing of Treponema pallidum in Denmark: a Nationwide Study of Syphilis","volume":"96","author":"Salado-Rasmussen","year":"2016","journal-title":"Acta Derm. Venereol."},{"key":"10.1016\/j.meegid.2019.104049_bb0255","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/OLQ.0000000000000734","article-title":"Molecular typing and macrolide resistance of Syphilis cases in Manitoba, Canada, From 2012 to 2016","volume":"45","author":"Shuel","year":"2018","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0260","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1097\/OLQ.0b013e31826f36de","article-title":"Prevalence of the 23S rRNA A2058G Point Mutation and Molecular Subtypes in Treponema pallidum in the United States, 2007 to 2009","volume":"39","author":"Su","year":"2012","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.meegid.2019.104049_bb0265","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1086\/320698","article-title":"Molecular subtyping of Treponema pallidum in an Arizona County with increasing syphilis morbidity: use of specimens from ulcers and blood","volume":"183","author":"Sutton","year":"2001","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0270","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1128\/JCM.00341-12","article-title":"Evaluation of macrolide resistance and enhanced molecular typing of Treponema pallidum in patients with syphilis in Taiwan: a prospective multicenter study","volume":"50","author":"Wu","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2019.104049_bb0275","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/OLQ.0000000000000445","article-title":"Molecular subtyping and surveillance of resistance genes in Treponema pallidum DNA from patients with secondary and latent syphilis in Hunan, China","volume":"43","author":"Xiao","year":"2016","journal-title":"Sex. Transm. Dis."},{"key":"10.1016\/j.meegid.2019.104049_bb0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2015.04.018","article-title":"Unexpectedly high prevalence of Treponema pallidum infection in the oral cavity of human immunodeficiency virus-infected patients with early syphilis who had engaged in unprotected sex practices","volume":"21","author":"Yang","year":"2015","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.meegid.2019.104049_bb0285","article-title":"Molecular subtyping of Treponema pallidum and associated factors of serofast status in early syphilis patients: Identified novel genotype and cytokine marker","volume":"12","author":"Zhang","year":"2017","journal-title":"PLoS One"}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134819302758?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134819302758?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T14:42:19Z","timestamp":1761576139000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134819302758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":57,"alternative-id":["S1567134819302758"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2019.104049","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A comparison of genotyping tool in Treponema pallidum: Review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2019.104049","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104049"}}