{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T01:20:54Z","timestamp":1777166454872,"version":"3.51.4"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81802046"],"award-info":[{"award-number":["81802046"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014361","name":"Hubei University of Medicine","doi-asserted-by":"publisher","award":["HBMUPI202101"],"award-info":[{"award-number":["HBMUPI202101"]}],"id":[{"id":"10.13039\/501100014361","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.meegid.2022.105286","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T21:02:21Z","timestamp":1650661341000},"page":"105286","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Single-nucleotide polymorphisms of artemisinin resistance-related pfubp1 and pfap2mu genes in imported Plasmodium falciparum to Wuhan, China"],"prefix":"10.1016","volume":"101","author":[{"given":"Weijia","family":"Cheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaonan","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weixing","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.meegid.2022.105286_bb0005","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/s13071-018-2762-3","article-title":"Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates","volume":"11","author":"Adams","year":"2018","journal-title":"Parasit. Vectors"},{"issue":"7481","key":"10.1016\/j.meegid.2022.105286_bb0010","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/nature12876","article-title":"A molecular marker of artemisinin-resistant Plasmodium falciparum malaria","volume":"505","author":"Ariey","year":"2014","journal-title":"Nature."},{"issue":"6473","key":"10.1016\/j.meegid.2022.105286_bb0015","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1126\/science.aax4735","article-title":"A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites","volume":"367","author":"Birnbaum","year":"2020","journal-title":"Science"},{"issue":"6077","key":"10.1016\/j.meegid.2022.105286_bb0020","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1126\/science.1215966","article-title":"A major genome region underlying artemisinin resistance in malaria","volume":"336","author":"Cheeseman","year":"2012","journal-title":"Science."},{"issue":"12","key":"10.1016\/j.meegid.2022.105286_bb0025","doi-asserted-by":"crossref","first-page":"4455","DOI":"10.1039\/D0SC05717G","article-title":"Universal and high-fidelity DNA single nucleotide polymorphism detection based on a CRISPR\/Cas12a biochip","volume":"12","author":"Chen","year":"2021","journal-title":"Chem. Sci."},{"issue":"1","key":"10.1016\/j.meegid.2022.105286_bb0030","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1186\/s12936-021-03737-8","article-title":"Molecular surveillance of anti-malarial resistance pfcrt, pfmdr1, and pfk13 polymorphisms in African Plasmodium falciparum imported parasites to Wuhan, China","volume":"20","author":"Cheng","year":"2021","journal-title":"Malar. J."},{"issue":"1","key":"10.1016\/j.meegid.2022.105286_bb0035","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s40249-016-0151-8","article-title":"Malaria: global progress 2000\u20132015 and future challenges","volume":"5","author":"Cibulskis","year":"2016","journal-title":"Infect. Dis. Poverty"},{"issue":"5","key":"10.1016\/j.meegid.2022.105286_bb0040","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1056\/NEJMoa0808859","article-title":"Artemisinin resistance in Plasmodium falciparum malaria","volume":"361","author":"Dondorp","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.meegid.2022.105286_bb0045","doi-asserted-by":"crossref","first-page":"8847","DOI":"10.1038\/srep08847","article-title":"The plasmodium vivax in China: decreased in local cases but increased imported cases from Southeast Asia and Africa","volume":"5","author":"Feng","year":"2015","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.meegid.2022.105286_bb0050","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1186\/s12936-018-2444-9","article-title":"Ready for malaria elimination: zero indigenous case reported in the People\u2019s Republic of China","volume":"17","author":"Feng","year":"2018","journal-title":"Malar. J."},{"key":"10.1016\/j.meegid.2022.105286_bb0055","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/s12936-015-0783-3","article-title":"Identification of large variation in pfcrt, pfmdr-1 and pfubp-1 markers in Plasmodium falciparum isolates from Ethiopia and Tanzania","volume":"14","author":"Golassa","year":"2015","journal-title":"Malar. J."},{"key":"10.1016\/j.meegid.2022.105286_bb0060","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/1475-2875-12-118","article-title":"Artemisinin resistance in rodent malaria--mutation in the AP2 adaptor mu-chain suggests involvement of endocytosis and membrane protein trafficking","volume":"12","author":"Henriques","year":"2013","journal-title":"Malar. J."},{"issue":"12","key":"10.1016\/j.meegid.2022.105286_bb0065","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1093\/infdis\/jiu358","article-title":"Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT","volume":"210","author":"Henriques","year":"2014","journal-title":"J. Infect. Dis."},{"issue":"1","key":"10.1016\/j.meegid.2022.105286_bb0070","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1365-2958.2007.05753.x","article-title":"Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites","volume":"65","author":"Hunt","year":"2007","journal-title":"Mol. Microbiol."},{"issue":"1","key":"10.1016\/j.meegid.2022.105286_bb0075","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1186\/s12936-020-03509-w","article-title":"Molecular surveillance of anti-malarial resistance Pfdhfr and Pfdhps polymorphisms in African and Southeast Asia Plasmodium falciparum imported parasites to Wuhan, China","volume":"19","author":"Jiang","year":"2020","journal-title":"Malar. J."},{"issue":"7","key":"10.1016\/j.meegid.2022.105286_bb0080","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.pt.2013.04.001","article-title":"Antidogmatic approaches to artemisinin resistance: reappraisal as treatment failure with artemisinin combination therapy","volume":"29","author":"Krishna","year":"2013","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.meegid.2022.105286_bb0085","article-title":"CRISPR\/Cas9 gene editing to make conditional mutants of human malaria parasite P. falciparum","volume":"139","author":"Kudyba","year":"2018","journal-title":"J. Vis. Exp."},{"issue":"10","key":"10.1016\/j.meegid.2022.105286_bb0090","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1056\/NEJMc1612765","article-title":"Emergence of indigenous artemisinin-resistant Plasmodium falciparum in Africa","volume":"376","author":"Lu","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.meegid.2022.105286_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2019.104121","article-title":"Prevalence of mutations in Plasmodium falciparum genes associated with resistance to different antimalarial drugs in Nyando, Kisumu County in Kenya","volume":"78","author":"Musyoka","year":"2020","journal-title":"Infect. Genet. Evol."},{"issue":"24","key":"10.1016\/j.meegid.2022.105286_bb0100","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1056\/NEJMc0805011","article-title":"Evidence of artemisinin-resistant malaria in western Cambodia","volume":"359","author":"Noedl","year":"2008","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.meegid.2022.105286_bb0105","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.02382-16","article-title":"pfk13-independent treatment failure in four imported cases of Plasmodium falciparum malaria treated with Artemether-Lumefantrine in the United Kingdom","volume":"61","author":"Sutherland","year":"2017","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2022.105286_bb0110","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1186\/1475-2875-12-320","article-title":"Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers","volume":"12","author":"van Schalkwyk","year":"2013","journal-title":"Malar. J."},{"key":"10.1016\/j.meegid.2022.105286_bb0115","series-title":"Antimalarial Drug Combination Therapy","author":"WHO","year":"2001"},{"key":"10.1016\/j.meegid.2022.105286_bb0120","series-title":"Global Technical Strategy for Malaria 2016\u20132030","author":"WHO","year":"2015"},{"key":"10.1016\/j.meegid.2022.105286_bb0125","series-title":"World Malaria Report 2020","author":"WHO","year":"2021"},{"key":"10.1016\/j.meegid.2022.105286_bb0130","series-title":"Zeroing in on Malaria Elimination","author":"WHO","year":"2021"},{"issue":"1","key":"10.1016\/j.meegid.2022.105286_bb0135","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1186\/s12936-020-03387-2","article-title":"Molecular epidemiological surveillance of Africa and Asia imported malaria in Wuhan, Central China: comparison of diagnostic tools during 2011-2018","volume":"19","author":"Xie","year":"2020","journal-title":"Malar. J."},{"issue":"11","key":"10.1016\/j.meegid.2022.105286_bb0140","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00981-20","article-title":"Prevalence of Plasmodium falciparum Kelch 13 (PfK13) and ubiquitin-specific protease 1 (pfubp1) gene polymorphisms in returning travelers from Africa reported in Eastern China","volume":"64","author":"Yan","year":"2020","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134822000831?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134822000831?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T14:53:11Z","timestamp":1761576791000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134822000831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":28,"alternative-id":["S1567134822000831"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2022.105286","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Single-nucleotide polymorphisms of artemisinin resistance-related pfubp1 and pfap2mu genes in imported Plasmodium falciparum to Wuhan, China","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2022.105286","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105286"}}