{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T01:59:14Z","timestamp":1773453554881,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2004,1]]},"DOI":"10.1016\/j.mehy.2004.03.033","type":"journal-article","created":{"date-parts":[[2004,5,29]],"date-time":"2004-05-29T14:09:38Z","timestamp":1085839778000},"page":"841-846","source":"Crossref","is-referenced-by-count":15,"title":["Periodic dip of lipidperoxidation in humans: a redox signal to synchronize peripheral circadian clocks?"],"prefix":"10.1016","volume":"63","author":[{"given":"F.","family":"Cardona","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2004.03.033_BIB1","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0962-8924(98)01269-0","article-title":"How cells tell time","volume":"8","author":"Green","year":"1998","journal-title":"Trends Cell Biol"},{"key":"10.1016\/j.mehy.2004.03.033_BIB2","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0959-437X(99)00009-X","article-title":"The ins and outs of circadian timekeeping","volume":"9","author":"Brown","year":"1999","journal-title":"Curr. Opin. Genet. Dev"},{"key":"10.1016\/j.mehy.2004.03.033_BIB3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/neu.10164","article-title":"Genetic analysis of the circadian system in Drosophila melanogaster and mammals","volume":"54","author":"Stanewsky","year":"2003","journal-title":"J. Neurobiol"},{"key":"10.1016\/j.mehy.2004.03.033_BIB4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1126\/science.1087824","article-title":"Circadian rhythms. Clocks on the brain","volume":"301","author":"Green","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.mehy.2004.03.033_BIB5","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1126\/science.288.5466.682","article-title":"Resetting central and peripheral circadian oscillators in transgenic rats","volume":"288","author":"Yamazaki","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.mehy.2004.03.033_BIB6","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/S0092-8674(02)01225-4","article-title":"A web of circadian pacemakers","volume":"111","author":"Schibler","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.mehy.2004.03.033_BIB7","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1146\/annurev.physiol.63.1.647","article-title":"Molecular analysis of mammalian circadian rhythms","volume":"63","author":"Reppert","year":"2001","journal-title":"Annu. Rev. Physiol"},{"key":"10.1016\/j.mehy.2004.03.033_BIB8","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1046\/j.1365-2826.2003.00974.x","article-title":"Flies and fish: birds of a feather","volume":"15","author":"Tamai","year":"2003","journal-title":"J. Neuroendocrinol"},{"key":"10.1016\/j.mehy.2004.03.033_BIB9","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0891-5849(99)00242-7","article-title":"Oxidative stress and gene regulation","volume":"28","author":"Allen","year":"2000","journal-title":"Free Radical Biol. Med"},{"key":"10.1016\/j.mehy.2004.03.033_BIB10","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1126\/science.1060698","article-title":"Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors","volume":"293","author":"Rutter","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.mehy.2004.03.033_BIB11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3109\/10715769209049162","article-title":"Circadian rhythm of white blood cell aggregation and free radical status in healthy volunteers","volume":"16","author":"Bridges","year":"1992","journal-title":"Free Radical Res. Commun"},{"key":"10.1016\/j.mehy.2004.03.033_BIB12","series-title":"The pineal organ, its hormone melatonin, and the photoneuroendocrine system","author":"Korf","year":"1997"},{"key":"10.1016\/j.mehy.2004.03.033_BIB13","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1192\/bjp.161.3.361","article-title":"Plasma melatonin levels in anorexia nervosa","volume":"361","author":"Arendt","year":"1992","journal-title":"Brit. J. Psychiat"},{"key":"10.1016\/j.mehy.2004.03.033_BIB14","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1600-079X.1995.tb00147.x","article-title":"On the primary functions of melatonin in evolution: mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals","volume":"18","author":"Hardeland","year":"1995","journal-title":"J. Pineal Res"},{"key":"10.1016\/j.mehy.2004.03.033_BIB15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-079X.1995.tb00133.x","article-title":"A review of the evidence supporting melatonin's role as an antioxidant","volume":"18","author":"Reiter","year":"1995","journal-title":"J. Pineal Res"},{"key":"10.1016\/j.mehy.2004.03.033_BIB16","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/S0891-5849(00)00435-4","article-title":"Melatonin directly scanvanges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation","volume":"29","author":"Tan","year":"2000","journal-title":"Free Radical Biol. Med"},{"key":"10.1016\/j.mehy.2004.03.033_BIB17","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1600-079X.1995.tb00170.x","article-title":"Melatonin reduces H2O2-induced lipid peroxidation in homogenates of different rat brain regions","volume":"19","author":"Sewerynek","year":"1995","journal-title":"J. Pineal Res"},{"key":"10.1016\/j.mehy.2004.03.033_BIB18","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0197-0186(94)00154-M","article-title":"Melatonin stimulates brain glutathione peroxidase activity","volume":"26","author":"Barlow-Walden","year":"1995","journal-title":"Neurochem. Int"},{"key":"10.1016\/j.mehy.2004.03.033_BIB19","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0197-0186(97)00043-0","article-title":"Rhythms of glutathione peroxidase and glutathione reductase in brain of chick and their inhibition by light","volume":"32","author":"Pablos","year":"1998","journal-title":"Neurochem. Int"},{"key":"10.1016\/j.mehy.2004.03.033_BIB20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0891-5849(02)01186-3","article-title":"Melatonin does not directly scavenge hydrogen peroxide: demise of another myth","volume":"34","author":"Fowler","year":"2003","journal-title":"Free Radical Biol. Med"},{"key":"10.1016\/j.mehy.2004.03.033_BIB21","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0896-6273(00)80628-5","article-title":"Molecular analysis of mammalian timeless","volume":"21","author":"Zylka","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.mehy.2004.03.033_BIB22","doi-asserted-by":"crossref","first-page":"27039","DOI":"10.1074\/jbc.273.42.27039","article-title":"Multitissue circadian expression of rat period homolog (rPer2) mRNA is governed by the mammalian circadian clock, the suprachiasmatic nucleus in the brain","volume":"273","author":"Sakamoto","year":"1998","journal-title":"J. Biol. Chem"},{"key":"10.1016\/j.mehy.2004.03.033_BIB23","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1046\/j.1365-2826.2003.01001.x","article-title":"Melatonin: a clock-output, a clock-input","volume":"15","author":"Stehle","year":"2003","journal-title":"J. Neuroendocrinol"},{"key":"10.1016\/j.mehy.2004.03.033_BIB24","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1126\/science.280.5369.1564","article-title":"Role of the CLOCK protein in the mammalian circadian mechanism","volume":"280","author":"Gekakis","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.mehy.2004.03.033_BIB25","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1126\/science.1060699","article-title":"NPAS2: an analog of clock operative in the mammalian forebrain","volume":"293","author":"Reick","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.mehy.2004.03.033_BIB26","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1006\/bbrc.1998.9275","article-title":"Circadian oscillation of BMAL1, a partner of a mammalian clock gene Clock, in rat suprachiasmatic nucleus","volume":"250","author":"Honma","year":"1998","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"10.1016\/j.mehy.2004.03.033_BIB27","series-title":"Biochemie","author":"Stryer","year":"1999"},{"key":"10.1016\/j.mehy.2004.03.033_BIB28","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1126\/science.1063296","article-title":"Circadian rhythms. Chronobiology \u2013 reducing time","volume":"293","author":"Schibler","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.mehy.2004.03.033_BIB29","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1146\/annurev.biochem.71.090501.142857","article-title":"Metabolism and the control of circadian rhythms","volume":"71","author":"Rutter","year":"2000","journal-title":"Annu. Rev. Biochem"},{"key":"10.1016\/j.mehy.2004.03.033_BIB30","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1177\/074873049501000209","article-title":"Light treatment for sleep disorders: consensus report. VII. Jet lag","volume":"10","author":"Boulos","year":"1995","journal-title":"J. Biol. Rhythms"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987704002634?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987704002634?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,7]],"date-time":"2019-02-07T17:29:24Z","timestamp":1549560564000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987704002634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,1]]}},"alternative-id":["S0306987704002634"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2004.03.033","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2004,1]]}}}