{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T08:21:18Z","timestamp":1717230078781},"reference-count":14,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.mehy.2004.12.029","type":"journal-article","created":{"date-parts":[[2005,3,31]],"date-time":"2005-03-31T12:33:57Z","timestamp":1112272437000},"page":"374-376","source":"Crossref","is-referenced-by-count":2,"title":["Proposal for using small molecule tumor necrosis factor-alpha lowering agents, possibly bupropion, in aplastic anemia"],"prefix":"10.1016","volume":"65","author":[{"given":"Richard E.","family":"Kast","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric Lewin","family":"Altschuler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2004.12.029_bib1","first-page":"165","article-title":"Acquired aplastic anemia","volume":"17","author":"Keohane","year":"2004","journal-title":"Clin Lab Sci"},{"key":"10.1016\/j.mehy.2004.12.029_bib2","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1080\/10428190310001602363","article-title":"Evolution of clonal cytogenetic abnormalities in aplastic anemis","volume":"45","author":"Maciejewski","year":"2004","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.mehy.2004.12.029_bib3","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0092-8674(04)00166-7","article-title":"Tumor necrosis factor: an apoptosis JuNKie?","volume":"116","author":"Varfolomeev","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.mehy.2004.12.029_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1119(03)00841-2","article-title":"Tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology","volume":"321","author":"Nanes","year":"2003","journal-title":"Gene"},{"key":"10.1016\/j.mehy.2004.12.029_bib5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1600-0609.1996.tb01646.x","article-title":"Immune pathophysiology of acquired aplastic anemia","volume":"60","author":"Young","year":"1996","journal-title":"Eur J Haematol Suppl"},{"key":"10.1016\/j.mehy.2004.12.029_bib6","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.exphem.2004.06.004","article-title":"Transcript profile of CD4+ and CD8+ T cells from the bone marrow of acquired aplastic anemia patients","volume":"32","author":"Zeng","year":"2004","journal-title":"Exp Hematol"},{"key":"10.1016\/j.mehy.2004.12.029_bib7","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1600-0609.2004.00259.x","article-title":"Excessive production of TNF-alpha by bone marrow T lymphocytes is essential in causing bone marrow failure in patients with aplastic anemia","volume":"73","author":"Hara","year":"2004","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.mehy.2004.12.029_bib8","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1046\/j.1365-2141.2001.03212.x","article-title":"Interferon-gamma and TNF-alpha are over expressed in bone marrow T lymphocytes from pediatric patients with aplastic anemia","volume":"115","author":"Dufour","year":"2001","journal-title":"Br J Haematol"},{"key":"10.1016\/j.mehy.2004.12.029_bib9","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/sj.thj.6200174","article-title":"Interleukin-10 inhibits in vitro hematopoietic suppression and production of interferon-gamma and TNF-alpha by peripheral blood mononuclear cells from patients with aplastic anemia","volume":"3","author":"Geissler","year":"2002","journal-title":"Hematol J"},{"key":"10.1016\/j.mehy.2004.12.029_bib10","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/ajh.1170","article-title":"TNF-alpha levels in long term marrow cultures from patients with aplastic anemia: modulation by gametocyte-macrophage colony-stimulating factor","volume":"68","author":"Martinez-Jaramillo","year":"2001","journal-title":"Am J Hematol"},{"key":"10.1016\/j.mehy.2004.12.029_bib11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1046\/j.1365-2141.2002.03592.x","article-title":"Hypoplastic myelodysplastic syndromes can be distinguished from acquired aplastic anemia by bone marrow stem cell expression of the TNF-alpha receptor","volume":"118","author":"Kasahara","year":"2002","journal-title":"Br J Haematol"},{"key":"10.1016\/j.mehy.2004.12.029_bib12","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1053\/gast.2001.29467","article-title":"Remission of Crohn\u2019s disease on bupropion","volume":"121","author":"Kast","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mehy.2004.12.029_bib13","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/j.gastro.2003.02.004","article-title":"Crohn\u2019s disease remission on bupropion","volume":"125","author":"Kane","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mehy.2004.12.029_bib14","unstructured":"Altschuler EL, Kast RE. Bupropion (wellbutrin) lowers tumor necrosis factor-alpha (TNF) levels: implications for disease treatment. Program No. 105.8. Abstract Viewer\/Itinerary Planner, Society for Neuroscience, Washington, DC; 2003"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987705000940?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987705000940?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T12:16:41Z","timestamp":1706098601000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987705000940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0306987705000940"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2004.12.029","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}