{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T13:51:06Z","timestamp":1773409866771,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.mehy.2006.05.030","type":"journal-article","created":{"date-parts":[[2006,7,8]],"date-time":"2006-07-08T11:20:27Z","timestamp":1152357627000},"page":"1320-1325","source":"Crossref","is-referenced-by-count":6,"title":["Scleral edge, not optic disc or retina, is the primary site of injury in chronic glaucoma"],"prefix":"10.1016","volume":"67","author":[{"given":"Syed Sikandar","family":"Hasnain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2006.05.030_bib1","series-title":"Disease of the lens and vitreous, glaucoma and hypotony","volume":"vol. XI","author":"Duke-Elder","year":"1969"},{"key":"10.1016\/j.mehy.2006.05.030_bib2","series-title":"Anatomy of the eye and orbit","author":"Wolff","year":"1968"},{"key":"10.1016\/j.mehy.2006.05.030_bib3","series-title":"Anatomy of the eye and orbit","author":"Wolff","year":"1968"},{"key":"10.1016\/j.mehy.2006.05.030_bib4","series-title":"Ophthalmology","article-title":"Papilledema and raised intracraniel pressure","author":"Sadun","year":"1999"},{"key":"10.1016\/j.mehy.2006.05.030_bib5","series-title":"Diseases of the lens and vitreous glaucoma and hypotony","volume":"vol. XI","author":"Duke-Elder","year":"1969"},{"key":"10.1016\/j.mehy.2006.05.030_bib6","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1001\/archopht.1981.03930010139020","article-title":"Regional differences in the structure of the lamina cribrosa and their reaction to the glaucomatous damage","volume":"99","author":"Quigly","year":"1981","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.mehy.2006.05.030_bib7","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.ajo.2004.04.054","article-title":"Risk assessment in the management of patients with ocular hypertension [perspective]","volume":"138","author":"Weinreb","year":"2004","journal-title":"Am J Opthalmol"},{"key":"10.1016\/j.mehy.2006.05.030_bib8","series-title":"Anatomy of the eye and orbit","author":"Wolff","year":"1968"},{"key":"10.1016\/j.mehy.2006.05.030_bib9","series-title":"Adler\u2019s physiology of the eye","first-page":"215","article-title":"Ocular circulation","author":"Bill","year":"1975"},{"key":"10.1016\/j.mehy.2006.05.030_bib10","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/0002-9394(76)90489-X","article-title":"Histologic studies of the vasculature of the anterior optic nerve","volume":"85","author":"Lieberman","year":"1976","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.mehy.2006.05.030_bib11","series-title":"Glaucoma; Conceptions of a disease","first-page":"78","article-title":"Structure and blood supply of the optic nerve","author":"Hayreh","year":"1978"},{"key":"10.1016\/j.mehy.2006.05.030_bib12","series-title":"The Pathogenesis of nerve damage in glaucoma","author":"Spaeth","year":"1977"},{"key":"10.1016\/j.mehy.2006.05.030_bib13","series-title":"Becker\u2013Shaffer\u2019s diagnosis and therapy of the glaucomas","author":"Kolker","year":"1976"},{"issue":"18","key":"10.1016\/j.mehy.2006.05.030_bib14","first-page":"37","article-title":"Chronic ischemia may be a major factor in glaucoma pathogenesis","volume":"23","author":"Hasnain","year":"2005","journal-title":"Ocular Surgery News"},{"key":"10.1016\/j.mehy.2006.05.030_bib15","unstructured":"Hasnain SS. Smoking greatly increases the risk of normal tension glaucoma. Available from: http:\/\/www.hasnaineye.com\/research.html."},{"key":"10.1016\/j.mehy.2006.05.030_bib16","series-title":"Ocular pathology","author":"Yanoff","year":"1975"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987706003811?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987706003811?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T06:55:08Z","timestamp":1547535308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987706003811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0306987706003811"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2006.05.030","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}