{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T18:40:15Z","timestamp":1683657615441},"reference-count":77,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1016\/j.mehy.2006.09.029","type":"journal-article","created":{"date-parts":[[2006,11,10]],"date-time":"2006-11-10T12:28:04Z","timestamp":1163161684000},"page":"1126-1133","source":"Crossref","is-referenced-by-count":2,"title":["Treatment of essential hypertension and non-insulin dependent diabetes mellitus with vitamin C"],"prefix":"10.1016","volume":"68","author":[{"given":"Narayan V.","family":"Nimbkar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatimah","family":"Lateef","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.mehy.2006.09.029_bib1","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.mehy.2005.06.023","article-title":"Carotid body dysfunction: the possible etiology of non-insulin dependent diabetes mellitus and essential hypertension","volume":"65","author":"Nimbkar","year":"2005","journal-title":"Med Hypotheses"},{"issue":"17","key":"10.1016\/j.mehy.2006.09.029_bib2","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1056\/NEJM199704173361601","article-title":"A clinical trial of the effects of dietary patterns on blood pressure","volume":"336","author":"Appel","year":"1997","journal-title":"N Eng J Med"},{"issue":"5","key":"10.1016\/j.mehy.2006.09.029_bib3","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/sj.ejcn.1601162","article-title":"Fruit and vegetable intake and population glycosylated hemoglobin levels: the EPIC \u2013 Norfolk study","volume":"55","author":"Sargent","year":"2001","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.mehy.2006.09.029_bib4","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1161\/01.HYP.0000039962.68332.59","article-title":"Serum antioxidant vitamins and blood pressure in the United States population","volume":"40","author":"Chen","year":"2002","journal-title":"Hypertension"},{"issue":"Suppl. 3","key":"10.1016\/j.mehy.2006.09.029_bib5","doi-asserted-by":"crossref","first-page":"610S","DOI":"10.1093\/ajcn\/78.3.610S","article-title":"Type 2 diabetes and the vegetarian diet","volume":"78","author":"Jenkins","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.mehy.2006.09.029_bib6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.33549\/physiolres.930444","article-title":"Lipid peroxidation and nutrition","volume":"53","author":"Krajkovicova-Kudlackova","year":"2004","journal-title":"Physiol Res"},{"key":"10.1016\/j.mehy.2006.09.029_bib7","doi-asserted-by":"crossref","first-page":"362","DOI":"10.2337\/diacare.27.2.362","article-title":"Dietary antioxidant intake and risk of type 2 diabetes","volume":"27","author":"Montonen","year":"2004","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mehy.2006.09.029_bib8","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1093\/aje\/kwh085","article-title":"Relation of vegetables, fruit and meat intake to 7-year blood pressure change in middle-aged men","volume":"159","author":"Miura","year":"2004","journal-title":"Am J Epidemiol"},{"issue":"5","key":"10.1016\/j.mehy.2006.09.029_bib9","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1024\/0300-9831.74.5.313","article-title":"Effect of high intake of fruit and vegetables on redox status in type 2 onset diabetes: a pilot study","volume":"74","author":"Giammarioli","year":"2004","journal-title":"Int J Vitam Nutr Res"},{"issue":"3","key":"10.1016\/j.mehy.2006.09.029_bib10","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/sj.ejcn.1602094","article-title":"Food consumption and the incidence of type II diabetes mellitus","volume":"59","author":"Montonen","year":"2005","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.mehy.2006.09.029_bib11","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1161\/01.CIR.94.10.2369","article-title":"Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering","volume":"94","author":"Azen","year":"1996","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.mehy.2006.09.029_bib12","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1271\/bbb.70.293","article-title":"Effect of chronic administration of fruit extract (citrus wushiu Marc) on glucose tolerance in GK rats, a model type 2 diabetes","volume":"70","author":"Sugiura","year":"2006","journal-title":"Biosci Biotechnol Biochem"},{"issue":"6","key":"10.1016\/j.mehy.2006.09.029_bib13","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1161\/01.STR.0000017220.78722.D7","article-title":"Plasma vitamin C modifies the association between hypertension and risk of stroke","volume":"33","author":"Kurl","year":"2002","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.mehy.2006.09.029_bib14","first-page":"343","article-title":"Inverse association of serum ascorbic acid level and blood pressure or rate of hypertension in male adults aged 30\u201339 years","volume":"54","author":"Yoshioka","year":"1984","journal-title":"Int J Vitam Nutr Res"},{"issue":"7","key":"10.1016\/j.mehy.2006.09.029_bib15","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1097\/00004872-199816070-00005","article-title":"Does vitamin C reduce blood pressure? Results of a large study aged 65 or older","volume":"16","author":"Bates","year":"1998","journal-title":"J Hypertens"},{"key":"10.1016\/j.mehy.2006.09.029_bib16","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1161\/01.HYP.37.2.261","article-title":"Ascorbic acid status and subsequent diastolic and systolic blood pressure","volume":"37","author":"Block","year":"2001","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.mehy.2006.09.029_bib17","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/00004872-199604000-00014","article-title":"Vitamin C status and blood pressure","volume":"14","author":"Ness","year":"1996","journal-title":"J Hypertens"},{"key":"10.1016\/j.mehy.2006.09.029_bib18","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s11010-005-5424-7","article-title":"Different antioxidant status, total antioxidant power and free radicals in essential hypertension","volume":"277","author":"Kashyap","year":"2005","journal-title":"Mol Cell Biochem."},{"key":"10.1016\/j.mehy.2006.09.029_bib19","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1161\/01.HYP.31.2.621","article-title":"Low-density lipoprotein oxidation and vitamin E and C in sustained and white-coat hypertension","volume":"31","author":"Pierdomenico","year":"1998","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.mehy.2006.09.029_bib20","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1093\/ajcn\/74.3.402","article-title":"Antioxidant vitamin status and carotid atherosclerosis in the elderly","volume":"74","author":"Gale","year":"2001","journal-title":"Am J Clin Nutr"},{"issue":"4","key":"10.1016\/j.mehy.2006.09.029_bib21","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.freeradbiomed.2005.10.051","article-title":"Fastr plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation","volume":"40","author":"Bruno","year":"2006","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.mehy.2006.09.029_bib22","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1042\/0264-6021:3460491","article-title":"Vitamin C protects against and reverses specific hypochlorous acid and chloramines-dependent modification of low-density lipoproteins","volume":"346 Pt 2","author":"Carr","year":"2000","journal-title":"Biochem J"},{"issue":"1","key":"10.1016\/j.mehy.2006.09.029_bib23","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3181\/00379727-206-43722","article-title":"The effects of vitamin C and urate on the oxidation kinetics of human low-density lipoprotein","volume":"206","author":"Ma","year":"1994","journal-title":"Proc Soc Exp Biol Med"},{"issue":"2-3","key":"10.1016\/j.mehy.2006.09.029_bib24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1078\/0944-7113-00380","article-title":"Synergistic inhibition of low-density lipoprotein oxidation by rutin, gamma-terpine, and ascorbic acid","volume":"11","author":"Milde","year":"2004","journal-title":"Phytomedicine"},{"issue":"1-2","key":"10.1016\/j.mehy.2006.09.029_bib25","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0021-9150(96)06064-9","article-title":"Ascorbate and urate are the strongest determinants of plasma antioxidative capacity and serum resistance to oxidation in Finnish men","volume":"130","author":"Nyyssonen","year":"1997","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.mehy.2006.09.029_bib26","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1096\/fasebj.13.10.1145","article-title":"Vitamin E: function and metabolism","volume":"13","author":"Brigelius-Flohe","year":"1999","journal-title":"FASEB"},{"issue":"3-4","key":"10.1016\/j.mehy.2006.09.029_bib27","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1515\/BC.2002.065","article-title":"Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C","volume":"383","author":"Carr","year":"2002","journal-title":"Biol Chem"},{"issue":"3","key":"10.1016\/j.mehy.2006.09.029_bib28","first-page":"275","article-title":"l-ascorbic acid, l-ascorbate 2-sulfate, and atherogenesis","volume":"46","author":"Finnamore","year":"1976","journal-title":"Int J Vitam Nutr"},{"issue":"3","key":"10.1016\/j.mehy.2006.09.029_bib29","first-page":"301","article-title":"Effects of ascorbic acid on blood pressure and ascorbic acid metabolism in spontaneously hypertensive rats (SH rats)","volume":"55","author":"Yoshioka","year":"1985","journal-title":"Int J Vitam Nutr Res"},{"key":"10.1016\/j.mehy.2006.09.029_bib30","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0140-6736(96)90866-1","article-title":"Randomised controlled trial of vitamin E in patients with coronary disease: cambridge heart antioxidant study (CHAOS)","volume":"347","author":"Stephens","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.mehy.2006.09.029_bib31","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1161\/01.HYP.0000039961.13718.00","article-title":"Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes","volume":"40","author":"Mullan","year":"2000","journal-title":"Hypertension"},{"issue":"11","key":"10.1016\/j.mehy.2006.09.029_bib32","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1046\/j.1365-2796.2000.00752.x","article-title":"Antioxidant supplementation in atherosclerosis prevention (SAP) study: a randomized trial of effect of vitamin E and C on 3-year progression of carotid atherosclerosis","volume":"248","author":"Salonen","year":"2000","journal-title":"J Intern Med"},{"key":"10.1016\/j.mehy.2006.09.029_bib33","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1161\/01.ATV.14.2.177","article-title":"Arterial imaging and atherosclerosis reversal","volume":"14","author":"Blankenhorn","year":"1994","journal-title":"Arterioscler Thromb"},{"key":"10.1016\/j.mehy.2006.09.029_bib34","first-page":"241","article-title":"Regression of peripheral atherosclerosis during therapy with high doses of nicotinic acid","volume":"99","author":"\u00d6st","year":"1967","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1016\/j.mehy.2006.09.029_bib35","doi-asserted-by":"crossref","first-page":"139","DOI":"10.7326\/0003-4819-86-2-139","article-title":"Regression and progression of early femoral atherosclerosis in treated hyperlipoproteinemic patients","volume":"86","author":"Barndt","year":"1977","journal-title":"Ann Int Med"},{"key":"10.1016\/j.mehy.2006.09.029_bib36","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1161\/01.CIR.69.2.313","article-title":"Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI type II coronary intervention study","volume":"69","author":"Brensike","year":"1984","journal-title":"Circulation"},{"key":"10.1016\/j.mehy.2006.09.029_bib37","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1056\/NEJM198503283121301","article-title":"Diet, lipoproteins, and the progression of coronary atherosclerosis: the Leiden intervention trial","volume":"312","author":"Arntzenius","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1016\/j.mehy.2006.09.029_bib38","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1001\/jama.1987.03390230069027","article-title":"Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts","volume":"257","author":"Blankenhorn","year":"1987","journal-title":"JAMA"},{"key":"10.1016\/j.mehy.2006.09.029_bib39","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0140-6736(90)91656-U","article-title":"Can lifestyle changes reverse coronary heart disease? The lifestyle heart trial","volume":"336","author":"Ornish","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.mehy.2006.09.029_bib40","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1001\/jama.1990.03450230043027","article-title":"Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens","volume":"264","author":"Kane","year":"1990","journal-title":"JAMA"},{"key":"10.1016\/j.mehy.2006.09.029_bib41","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1056\/NEJM199011083231901","article-title":"Regression of coronary disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B","volume":"323","author":"Brown","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.mehy.2006.09.029_bib42","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1056\/NEJM199010043231404","article-title":"Effect of partial ileal bypass surgery on mortality and morbidity from coronary heart disease in patients with hypercholesterolemia: report of the program on the surgical control of the hyperlipidemias (POSCH)","volume":"323","author":"Buchwald","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.mehy.2006.09.029_bib43","doi-asserted-by":"crossref","first-page":"3013","DOI":"10.1001\/jama.1990.03450230049028","article-title":"Beneficial effects of colestipol-niacin on coronary atherosclerosis: a 4-year follow-up","volume":"264","author":"Cashin-Hemphill","year":"1990","journal-title":"JAMA"},{"key":"10.1016\/j.mehy.2006.09.029_bib44","first-page":"14001","article-title":"Beneficial angiographic and clinical response to multifactor modification in the standard coronary risk intervention oriject (SCRIP)","volume":"11","author":"Alderman","year":"1991","journal-title":"Arterioscler Thromb"},{"key":"10.1016\/j.mehy.2006.09.029_bib45","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0140-6736(92)90863-X","article-title":"Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St. Thomas\u2019 Atherosclerosis Regression Study (STARS)","volume":"339","author":"Watts","year":"1992","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.mehy.2006.09.029_bib46","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1161\/01.STR.24.12.1779","article-title":"One year reduction and longitudinal analysis of carotid intima-media thickness associated with colestipol\/niacin therapy","volume":"24","author":"Mack","year":"1993","journal-title":"Stroke"},{"issue":"6","key":"10.1016\/j.mehy.2006.09.029_bib47","doi-asserted-by":"crossref","first-page":"548","DOI":"10.7326\/0003-4819-124-6-199603150-00002","article-title":"Reduction in carotid arterial wall thickness using lovastatin and dietary therapy: a randomized controlled clinical trial","volume":"124","author":"Hodis","year":"1996","journal-title":"Ann Intern Med"},{"issue":"Suppl. 1","key":"10.1016\/j.mehy.2006.09.029_bib48","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1023\/A:1007787713191","article-title":"Retardation of coronary atherosclerosis: the bezafibrate coronary atherosclerosis intervention trial (BECAIT) and other angiographic trials","volume":"11","author":"de Faire","year":"1997","journal-title":"Cardiovasc Drugs Ther"},{"issue":"3","key":"10.1016\/j.mehy.2006.09.029_bib49","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1161\/01.CIR.104.3.249","article-title":"Effects of lipid-lowering by simvastatin on human atherosclerosis lesions: a longitudinal study by high-resolution, noninvasive magnetic resonance imaging","volume":"104","author":"Corti","year":"2001","journal-title":"Circulation"},{"issue":"Suppl. 12A","key":"10.1016\/j.mehy.2006.09.029_bib50","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.amjmed.2005.09.020","article-title":"Halting the progression of atherosclerosis with intensive lipid lowering: results from the reversal of atherosclerosis with aggressive lipid lowering (REVERSAL) trial","volume":"118","author":"Nissen","year":"2005","journal-title":"Am J Med"},{"issue":"1","key":"10.1016\/j.mehy.2006.09.029_bib51","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1507\/endocrj.52.95","article-title":"Increased risk for atherosclerosis estimated by pulse wave velocity in hypothyroidism and its reversal with appropriate treatment","volume":"52","author":"Hamano","year":"2005","journal-title":"Endocr J"},{"key":"10.1016\/j.mehy.2006.09.029_bib52","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1001\/jama.1995.03520470057032","article-title":"Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis","volume":"273","author":"Hodis","year":"1995","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.mehy.2006.09.029_bib53","doi-asserted-by":"crossref","first-page":"34C","DOI":"10.1016\/S0002-9149(99)80468-8","article-title":"The Kuopio atherosclerosis prevention study (KAPS): effect of pravastatin treatment on lipids, oxidation resistance of lipoproteins and atherosclerotic progression","volume":"76","author":"Salonen","year":"1995","journal-title":"Am J Cardiol"},{"issue":"2A","key":"10.1016\/j.mehy.2006.09.029_bib54","doi-asserted-by":"crossref","first-page":"9S","DOI":"10.1016\/S0002-9343(98)00040-0","article-title":"Therapeutic efficacy of the lipid-lowering armamentarium: the clinical benefits of aggressive lipid lowering therapy","volume":"104","author":"Hunninghake","year":"1998","journal-title":"Am J Med"},{"issue":"3","key":"10.1016\/j.mehy.2006.09.029_bib55","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/j.1744-9987.1997.tb00149.x","article-title":"The retardation of progression, stabilization, and regression of coronary and carotid atherosclerosis by low-density lipoproteins apherasis in patients with familial hypercholesterolemia","volume":"1","author":"Koga","year":"1997","journal-title":"Ther Apher"},{"issue":"4","key":"10.1016\/j.mehy.2006.09.029_bib56","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1023\/A:1007816300468","article-title":"Efficacy of two lipid-lowering treatments on quantitative coronary angiographic endpoints","volume":"14","author":"Mack","year":"2000","journal-title":"Cardiovasc Drugs Ther"},{"issue":"23","key":"10.1016\/j.mehy.2006.09.029_bib57","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1161\/01.CIR.0000041255.88750.F0","article-title":"Lipid lowering by simvastatin induces regression of human atherosclerosis lesions: two years\u2019 follow-up by high-resolution noninvasive magnetic resonance imaging","volume":"106","author":"Corti","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.mehy.2006.09.029_bib58","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1126\/science.6710156","article-title":"\u03b2-Carotene: an unusual type of lipid antioxidant","volume":"224","author":"Burton","year":"1984","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.mehy.2006.09.029_bib59","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1080\/10715760000301501","article-title":"Antioxidative efficacy of parallel and combined supplementation with coenzyme Q10 and d-alpha-tocopherol in mildly hypercholesterolemic subjects: a randomized placebo-controlled clinical study","volume":"33","author":"Kaikkonen","year":"2000","journal-title":"Free Rad Res"},{"key":"10.1016\/j.mehy.2006.09.029_bib60","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1096\/fasebj.13.9.1007","article-title":"Does vitamin C act as a pro-oxidant under physiological conditions?","volume":"13","author":"Carr","year":"1999","journal-title":"FASEB"},{"issue":"6","key":"10.1016\/j.mehy.2006.09.029_bib61","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S0891-5849(96)00491-1","article-title":"Evolutionary significance of vitamin C biosynthesis in terrestrial vertebrates","volume":"22","author":"Nandi","year":"1997","journal-title":"Free Radical Biol Med"},{"key":"10.1016\/j.mehy.2006.09.029_bib62","doi-asserted-by":"crossref","first-page":"4656","DOI":"10.1073\/pnas.88.11.4656","article-title":"Glutathione deficiency decreases tissue ascorbate levels in new born rats: ascorbate spares glutathione and protects","volume":"88","author":"Martensson","year":"1991","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.mehy.2006.09.029_bib63","doi-asserted-by":"crossref","first-page":"9360","DOI":"10.1073\/pnas.88.20.9360","article-title":"Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stress","volume":"88","author":"Martensson","year":"1991","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.mehy.2006.09.029_bib64","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1073\/pnas.90.1.317","article-title":"Glutathione ester delays the onset of scurvy in ascorbate-deficient guinea pigs","volume":"90","author":"Martensson","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.mehy.2006.09.029_bib65","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1161\/01.RES.87.5.349","article-title":"Potential antiatherogenic mechanism of ascorbate (vitamin C) and \u03b1-tocopherol (vitamin E)","volume":"87","author":"Carr","year":"2000","journal-title":"Circ Res"},{"issue":"2","key":"10.1016\/j.mehy.2006.09.029_bib66","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/BF03179812","article-title":"Vitamin E action, metabolism and perspectives","volume":"57","author":"Herrera","year":"2001","journal-title":"J Physiol Biochem"},{"key":"10.1016\/j.mehy.2006.09.029_bib67","doi-asserted-by":"crossref","first-page":"3704","DOI":"10.1073\/pnas.93.8.3704","article-title":"Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance","volume":"93","author":"Levine","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.mehy.2006.09.029_bib68","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1023\/A:1012186203165","article-title":"Pharmacokinetic model of ascorbic acidin healthy male volunteers during depletion and repletion","volume":"14","author":"Graumlich","year":"1997","journal-title":"Pharm Res"},{"issue":"1","key":"10.1016\/j.mehy.2006.09.029_bib69","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1080\/07315724.2003.10719272","article-title":"Vitamin C as an antioxidant: evaluation of its role in disease prevention","volume":"22","author":"Padayatty","year":"2003","journal-title":"J Am Coll Nutr"},{"issue":"1","key":"10.1016\/j.mehy.2006.09.029_bib70","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0304-4165(86)90234-5","article-title":"The antioxidant efficiency of vitamin C is concentration-dependent","volume":"884","author":"Wayner","year":"1986","journal-title":"Biochim Biophys Acta"},{"issue":"5","key":"10.1016\/j.mehy.2006.09.029_bib71","doi-asserted-by":"crossref","first-page":"375","DOI":"10.2165\/00003088-199936050-00005","article-title":"The efficiency concept in pharmacodynamics","volume":"36","author":"Alvan","year":"1999","journal-title":"Clin Pharmacokin"},{"issue":"5","key":"10.1016\/j.mehy.2006.09.029_bib72","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.clnu.2004.01.007","article-title":"Vitamin C pharmacokinetics of plain and slow release formulations in smokers","volume":"23","author":"Viscovich","year":"2004","journal-title":"Clin Nutr"},{"issue":"4","key":"10.1016\/j.mehy.2006.09.029_bib73","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1042\/cs1030339","article-title":"Lack of effect of oral vitamin C on blood pressure, oxidative stress and endothelial function in Type II diabetes","volume":"103","author":"Darko","year":"2002","journal-title":"Clin Sci (Lond)"},{"issue":"3","key":"10.1016\/j.mehy.2006.09.029_bib74","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/jps.2600710304","article-title":"Ascorbic acid absorption in humans: a comparison among several dosage forms","volume":"71","author":"Yung","year":"1982","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.mehy.2006.09.029_bib75","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1161\/01.CIR.0000074221.68903.77","article-title":"Timing of antioxidant vitamin ingestion alters postprandial proatherogenic serum markers","volume":"108","author":"Carroll","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.mehy.2006.09.029_bib76","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1161\/01.ATV.0000136648.62973.c8","article-title":"Effects of long-term daily low-dose supplementation with antioxidant vitamins and minerals on structure and function of large arteries","volume":"24","author":"Zureik","year":"2004","journal-title":"Atheroscl Throm Vas"},{"issue":"7","key":"10.1016\/j.mehy.2006.09.029_bib77","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1016\/S0735-1097(01)01676-X","article-title":"Antioxidantvitamins and the risk of carotid atherosclerosis. The Perth carotid ultrasound disease assessment study (CUDAS)","volume":"38","author":"McQuillan","year":"2001","journal-title":"J Am Coll Cardiol"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987706006852?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987706006852?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T18:16:07Z","timestamp":1683656167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987706006852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":77,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["S0306987706006852"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2006.09.029","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}