{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T10:25:51Z","timestamp":1784111151317,"version":"3.55.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1016\/j.mehy.2007.04.012","type":"journal-article","created":{"date-parts":[[2007,6,11]],"date-time":"2007-06-11T13:04:40Z","timestamp":1181567080000},"page":"1222-1224","source":"Crossref","is-referenced-by-count":3,"title":["Trigger osteoclast formation and activation: Molecular treatment strategy of delayed tooth eruption"],"prefix":"10.1016","volume":"69","author":[{"given":"Fang","family":"Hua","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2007.04.012_bib1","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/(SICI)1097-0185(199606)245:2<374::AID-AR18>3.0.CO;2-M","article-title":"Tooth eruption: theories and facts","volume":"245","author":"Marks","year":"1996","journal-title":"Anat Rec"},{"key":"10.1016\/j.mehy.2007.04.012_bib2","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.ajodo.2003.10.031","article-title":"Delayed tooth eruption: pathogenesis, diagnosis, and treatment. A literature review","volume":"126","author":"Suri","year":"2004","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1016\/j.mehy.2007.04.012_bib3","first-page":"247","article-title":"Craniofacial abnormalities in osteopetrosis with precocious manifestations: report of a case with serial cephalometric roentgenograms","volume":"5","author":"Friede","year":"1985","journal-title":"J Craniofac Genet Dev Biol"},{"key":"10.1016\/j.mehy.2007.04.012_bib4","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0221-8747(81)90032-1","article-title":"The pathogenesis of infantile malignant osteopetrosis: bone mineral metabolism and complications in five infants","volume":"3","author":"Reeves","year":"1981","journal-title":"Metab Bone Dis Relat Res"},{"key":"10.1016\/j.mehy.2007.04.012_bib5","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/000163502753509446","article-title":"Dental aberrations in children and adolescents with osteogenesis imperfecta","volume":"60","author":"Malmgren","year":"2002","journal-title":"Acta Odontol Scand"},{"key":"10.1016\/j.mehy.2007.04.012_bib6","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1067\/moe.2000.103129","article-title":"Delayed eruption of permanent teeth in hyperimmunoglobulinemia E recurrent infection syndrome","volume":"89","author":"O\u2019Connell","year":"2000","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.mehy.2007.04.012_bib7","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/sj.bdj.4811712","article-title":"Eruptive tooth movement \u2013 the current state of knowledge","volume":"197","author":"Craddock","year":"2004","journal-title":"Br Dent J"},{"key":"10.1016\/j.mehy.2007.04.012_bib8","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0306-9877(85)90030-1","article-title":"The blood-vessel thrust theory of tooth eruption and migration","volume":"18","author":"Sutton","year":"1985","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.mehy.2007.04.012_bib9","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1177\/154411130201300403","article-title":"Cellular, molecular, and genetic determinants of tooth eruption","volume":"13","author":"Wise","year":"2002","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.mehy.2007.04.012_bib10","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.archoralbio.2004.11.016","article-title":"Osteoclast diseases and dental abnormalities","volume":"50","author":"Helfrich","year":"2005","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.mehy.2007.04.012_bib11","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1046\/j.0909-8836.1999.eos107610.x","article-title":"Gene expression of potential tooth eruption molecules in the dental follicle of the mouse","volume":"107","author":"Wise","year":"1999","journal-title":"Eur J Oral Sci"},{"key":"10.1016\/j.mehy.2007.04.012_bib12","first-page":"1677","article-title":"Implications for tooth eruption of the effect of interleukin-1alpha on nuclear factor-kappa B gene expression in the rat dental follicle","volume":"78","author":"Que","year":"1999","journal-title":"J Dent Res"},{"key":"10.1016\/j.mehy.2007.04.012_bib13","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/jemt.10375","article-title":"Osteoclast diseases","volume":"61","author":"Helfrich","year":"2003","journal-title":"Microsc Res Tech"},{"key":"10.1016\/j.mehy.2007.04.012_bib14","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1002\/art.20335","article-title":"Etanercept treatment of psoriatic arthritis: safety, efficacy, and effect on disease progression","volume":"50","author":"Mease","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.mehy.2007.04.012_bib15","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1002\/art.20967","article-title":"Sustained benefits of infliximab therapy for dermatologic and articular manifestations of psoriatic arthritis: results from the infliximab multinational psoriatic arthritis controlled trial","volume":"52","author":"Antoni","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.mehy.2007.04.012_bib16","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1016\/j.mehy.2006.04.062","article-title":"Inhibition of SHH signaling pathway: molecular treatment strategy of odontogenic keratocyst","volume":"67","author":"Zhang","year":"2006","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.mehy.2007.04.012_bib17","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/jcb.20674","article-title":"Anti-RANKL therapy for inflammatory bone disorders: mechanisms and potential clinical applications","volume":"97","author":"Anandarajah","year":"2006","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.mehy.2007.04.012_bib18","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1359\/jbmr.2001.16.2.348","article-title":"Osteoprotegerin (OPG) has potent and sustained antiresorptive activity in postmenopausal women","volume":"16","author":"Bekker","year":"2001","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.mehy.2007.04.012_bib19","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1517\/14712598.6.10.1041","article-title":"RANK ligand inhibition with denosumab for the management of osteoporosis","volume":"6","author":"Lewiecki","year":"2006","journal-title":"Expert Opin Boil Ther"},{"key":"10.1016\/j.mehy.2007.04.012_bib20","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.bbrc.2003.09.084","article-title":"Regulation of osteoclast protease expression by RANKL","volume":"310","author":"Wittrant","year":"2003","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987707002927?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987707002927?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,6]],"date-time":"2019-01-06T19:58:51Z","timestamp":1546804731000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987707002927"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["S0306987707002927"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2007.04.012","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}