{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T03:26:57Z","timestamp":1770434817216,"version":"3.49.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005357","name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja","doi-asserted-by":"publisher","award":["APVV-0122-06"],"award-info":[{"award-number":["APVV-0122-06"]}],"id":[{"id":"10.13039\/501100005357","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006109","name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV","doi-asserted-by":"publisher","award":["1\/0348\/09"],"award-info":[{"award-number":["1\/0348\/09"]}],"id":[{"id":"10.13039\/501100006109","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1016\/j.mehy.2009.03.031","type":"journal-article","created":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T07:00:17Z","timestamp":1240815617000},"page":"441-444","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Therapy with noninvasive ventilation in patients with obstructive sleep apnoea: Effects on atherogenic lipoprotein phenotype"],"prefix":"10.1016","volume":"73","author":[{"given":"Ruzena","family":"Tkacova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manfredi","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaspar","family":"Berneis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2009.03.031_bib1","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1164\/rccm.2109080","article-title":"Epidemiology of obstructive sleep apnea. A population health perspective","volume":"165","author":"Young","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib2","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/S0140-6736(05)71141-7","article-title":"Long-term cardiovascular outcomes in men with obstructive sleep apnea\u2013hypopnea with or without treatment with continuous positive airway pressure: an observational study","volume":"365","author":"Marin","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.mehy.2009.03.031_bib3","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1056\/NEJM200005113421901","article-title":"Prospective study of the association between sleep-disordered breathing and hypertension","volume":"342","author":"Peppard","year":"2000","journal-title":"New Engl J Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib4","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1183\/09031936.00043306","article-title":"Cardiovascular and metabolic effects of CPAP in obese males with OSA","volume":"29","author":"Coughlin","year":"2007","journal-title":"Eur Respir J"},{"key":"10.1016\/j.mehy.2009.03.031_bib5","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.pcad.2008.08.003","article-title":"Oxidative stress \u2013 a unifying paradigm in obstructive sleep apnea and comorbidities","volume":"51","author":"Lavie","year":"2009","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.mehy.2009.03.031_bib6","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1164\/rccm.200503-340OC","article-title":"Early signs of atherosclerosis in obstructive sleep apnea","volume":"172","author":"Drager","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib7","doi-asserted-by":"crossref","unstructured":"Third report of the National Cholesterol Education Program (NCEP). Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). Final report. Circulation 2002;106:3143\u2013421.","DOI":"10.1161\/circ.106.25.3143"},{"key":"10.1016\/j.mehy.2009.03.031_bib8","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1093\/aje\/154.1.50","article-title":"Relation of sleep-disordered breathing to cardiovascular disease risk factors: the sleep heart health study","volume":"154","author":"Newman","year":"2001","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.mehy.2009.03.031_bib9","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1136\/thx.2003.018739","article-title":"Circulating cardiovascular risk factors in obstructive sleep apnea: data from randomized controlled trials","volume":"59","author":"Robinson","year":"2004","journal-title":"Thorax"},{"key":"10.1016\/j.mehy.2009.03.031_bib10","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1183\/09031936.06.00067605","article-title":"Antioxidant status in patients with sleep apnoea and impact of continuous positive airway pressure treatment","volume":"27","author":"Barcelo","year":"2006","journal-title":"Eur Respir J"},{"key":"10.1016\/j.mehy.2009.03.031_bib11","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1161\/CIRCULATIONAHA.107.741512","article-title":"Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea","volume":"117","author":"Jelic","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.mehy.2009.03.031_bib12","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s11325-007-0160-8","article-title":"Exhaled breath markers in patients with obstructive sleep apnoea","volume":"12","author":"Petrosyan","year":"2008","journal-title":"Sleep Breath"},{"key":"10.1016\/j.mehy.2009.03.031_bib13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.sleep.2007.10.011","article-title":"Nasal continuous positive airway pressure treatment reduces systemic oxidative stress in patients with severe obstructive sleep apnea syndrome","volume":"10","author":"Christou","year":"2009","journal-title":"Sleep Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib14","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1378\/chest.08-0556","article-title":"Effects of continuous positive airway pressure on cardiovascular risk profile in patients with severe obstructive sleep apnea and metabolic syndrome","volume":"134","author":"Dorkova","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.mehy.2009.03.031_bib15","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1164\/rccm.200302-206OC","article-title":"Continuous positive airway pressure treatment rapidly improves insulin sensitivity in patients with obstructive sleep apnea syndrome","volume":"169","author":"Harsch","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib16","first-page":"CR117","article-title":"Long-term improvement of insulin sensitivity during CPAP therapy in the obstructive sleep apnoea syndrome","volume":"14","author":"Schahin","year":"2008","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.mehy.2009.03.031_bib17","doi-asserted-by":"crossref","first-page":"538","DOI":"10.5664\/jcsm.27347","article-title":"CPAP therapy of obstructive sleep apnea in type 2 diabetics improves glycemic control during sleep","volume":"4","author":"Dawson","year":"2008","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib18","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1183\/09031936.06.00131304","article-title":"Obstructive sleep apnoea and its therapy influence high-density lipoprotein cholesterol serum levels","volume":"27","author":"Borgel","year":"2006","journal-title":"Eur Respir J"},{"key":"10.1016\/j.mehy.2009.03.031_bib19","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1378\/chest.07-0074","article-title":"Effect of continuous positive airway pressure treatment on serum cardiovascular risk factors in patients with obstructive sleep apnea\u2013hypopnea syndrome","volume":"132","author":"Steiropoulos","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.mehy.2009.03.031_bib20","article-title":"Small, dense low-density lipoproteins (LDL) are predictors of cardio- and cerebro-vascular events in subjects with the metabolic syndrome","author":"Rizzo","year":"2008","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.mehy.2009.03.031_bib21","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1161\/01.CIR.98.21.2269","article-title":"Effects of continuous positive airway pressure on obstructive sleep apnea and left ventricular afterload in patients with heart failure","volume":"98","author":"Tkacova","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.mehy.2009.03.031_bib22","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1161\/01.ATV.0000229665.78997.0b","article-title":"Hypoxia converts human macrophages into triglyceride-loaded foam cells","volume":"26","author":"Bonstrom","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.mehy.2009.03.031_bib23","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1161\/01.RES.0000183879.60089.a9","article-title":"Intermittent hypoxia induces hyperlipidemia in lean mice","volume":"97","author":"Li","year":"2005","journal-title":"Circ Res"},{"key":"10.1016\/j.mehy.2009.03.031_bib24","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1152\/japplphysiol.01081.2006","article-title":"Hyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxia","volume":"102","author":"Li","year":"2007","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.mehy.2009.03.031_bib25","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1152\/japplphysiol.00522.2005","article-title":"Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice","volume":"99","author":"Li","year":"2005","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.mehy.2009.03.031_bib26","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1164\/ajrccm.165.5.2103001","article-title":"Obstructive sleep apnea is independently associated with insulin resistance","volume":"165","author":"Ip","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib27","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1210\/jc.2006-1705","article-title":"Atherogenic lipoprotein phenotype and low-density lipoproteins size and subclasses in women with polycystic ovary syndrome","volume":"92","author":"Berneis","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.mehy.2009.03.031_bib28","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.atherosclerosis.2007.03.034","article-title":"Atherogenic lipoprotein phenotype and LDL size and subclasses in patients with peripheral arterial disease","volume":"197","author":"Rizzo","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.mehy.2009.03.031_bib29","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1164\/rccm.200610-1527OC","article-title":"Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity","volume":"175","author":"Iiyori","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib30","doi-asserted-by":"crossref","first-page":"9520","DOI":"10.1074\/jbc.M111421200","article-title":"Diminished hepatic response to fasting\/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c","volume":"277","author":"Liang","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mehy.2009.03.031_bib31","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/nature00804","article-title":"Subendothelial retention of atherogenic lipoproteins in early atherosclerosis","volume":"417","author":"Skalen","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.mehy.2009.03.031_bib32","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.atherosclerosis.2005.04.024","article-title":"HDL dysfunction in obstructive sleep apnea","volume":"184","author":"Tan","year":"2006","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.mehy.2009.03.031_bib33","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/aje\/kwh261","article-title":"Sleep-disordered breathing, glucose intolerance, and insulin resistance. The sleep heart health study","volume":"160","author":"Punjabi","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.mehy.2009.03.031_bib34","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1164\/rccm.200308-1200OC","article-title":"Hypoxia causes glucose intolerance in humans","volume":"169","author":"Oltmanns","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mehy.2009.03.031_bib35","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1161\/01.ATV.21.2.282","article-title":"Atherogenic role of elevated CE transfer from HDL to VLDL(1) and dense LDL in type 2 diabetes: impact of the degree of triglyceridemia","volume":"21","author":"Guerin","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.mehy.2009.03.031_bib36","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1161\/01.ATV.0000107027.73816.ce","article-title":"Effects on lipoprotein subclasses of combined expression of human hepatic lipase and human apoB in transgenic rabbits","volume":"24","author":"Rizzo","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.mehy.2009.03.031_bib37","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jacc.2006.09.043","article-title":"Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study","volume":"49","author":"El Harchaoui","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.mehy.2009.03.031_bib38","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1161\/01.CIR.92.7.1770","article-title":"Prospective study of small LDLs as a risk factor for non-insulin dependent diabetes mellitus in elderly men and women","volume":"92","author":"Austin","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.mehy.2009.03.031_bib39","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1172\/JCI116541","article-title":"Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles","volume":"92","author":"Reaven","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1016\/j.mehy.2009.03.031_bib40","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1161\/01.CIR.88.2.381","article-title":"LDL subclass phenotypes and the insulin resistance syndrome in women","volume":"88","author":"Selby","year":"1993","journal-title":"Circulation"},{"key":"10.1016\/j.mehy.2009.03.031_bib41","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1161\/01.ATV.12.12.1496","article-title":"LDL subclass phenotypes and triglyceride metabolism in non-insulin-dependent diabetes","volume":"12","author":"Feingold","year":"1992","journal-title":"Arterioscler Thromb"},{"key":"10.1016\/j.mehy.2009.03.031_bib42","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2337\/diabetes.52.2.453","article-title":"Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance","volume":"52","author":"Garvey","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.mehy.2009.03.031_bib43","doi-asserted-by":"crossref","first-page":"379","DOI":"10.2165\/00129784-200505060-00005","article-title":"Beyond low-density lipoprotein: addressing the atherogenic lipid triad in type 2 diabetes mellitus and the metabolic syndrome","volume":"5","author":"Nesto","year":"2005","journal-title":"Am J Cardiovasc Drug"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987709002229?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987709002229?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:12:49Z","timestamp":1759691569000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987709002229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["S0306987709002229"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2009.03.031","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2009,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapy with noninvasive ventilation in patients with obstructive sleep apnoea: Effects on atherogenic lipoprotein phenotype","name":"articletitle","label":"Article Title"},{"value":"Medical Hypotheses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mehy.2009.03.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}