{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T18:40:47Z","timestamp":1698950447640},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.mehy.2009.06.015","type":"journal-article","created":{"date-parts":[[2009,7,22]],"date-time":"2009-07-22T05:08:09Z","timestamp":1248239289000},"page":"495-497","source":"Crossref","is-referenced-by-count":8,"title":["Could local delivery of bisphosphonates be a new therapeutic choice for hemangiomas?"],"prefix":"10.1016","volume":"73","author":[{"given":"Hejun","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.mehy.2009.06.015_bib1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/j.1651-2227.1955.tb04151.x","article-title":"Cutaneous hemangiomas in premature and mature infants","volume":"44","author":"Holmdahl","year":"1955","journal-title":"Acta Paediatr"},{"issue":"1","key":"10.1016\/j.mehy.2009.06.015_bib2","first-page":"8","article-title":"Strawberry hemangiomas; the natural history of the untreated lesion","volume":"86","author":"Jacobs","year":"1957","journal-title":"Calif Med"},{"issue":"3","key":"10.1016\/j.mehy.2009.06.015_bib3","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1097\/00006534-198203000-00002","article-title":"Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics","volume":"69","author":"Mulliken","year":"1982","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.mehy.2009.06.015_bib4","doi-asserted-by":"crossref","DOI":"10.1007\/s10456-009-9148-2","article-title":"Vasculogenesis in infantile hemangioma","author":"Boscolo","year":"2009","journal-title":"Angiogenesis"},{"issue":"4","key":"10.1016\/j.mehy.2009.06.015_bib5","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/(SICI)1096-9896(199608)179:4<403::AID-PATH604>3.0.CO;2-E","article-title":"High frequency of apoptosis in infantile capillary haemangioma","volume":"179","author":"Iwata","year":"1996","journal-title":"J Pathol"},{"issue":"2\u20133","key":"10.1016\/j.mehy.2009.06.015_bib6","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/sj.mn.7300009","article-title":"Increased apoptosis coincides with onset of involution in infantile hemangioma","volume":"5","author":"Razon","year":"1998","journal-title":"Microcirculation"},{"issue":"3","key":"10.1016\/j.mehy.2009.06.015_bib7","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1177\/120347549800200314","article-title":"The natural history of strawberry naevi","volume":"2","author":"Jackson","year":"1998","journal-title":"J Cutan Med Surg"},{"issue":"5","key":"10.1016\/j.mehy.2009.06.015_bib8","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1046\/j.1524-4725.2001.00227.x","article-title":"Hemangiomas: evaluation and treatment","volume":"27","author":"Dinehart","year":"2001","journal-title":"Dermatol Surg"},{"issue":"26","key":"10.1016\/j.mehy.2009.06.015_bib9","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1056\/NEJM199912233412614","article-title":"Hemangiomas in children","volume":"341","author":"Kushner","year":"1999","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.mehy.2009.06.015_bib10","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0022-3476(68)80208-2","article-title":"Successful treatment of juvenile hemangiomas with prednisone","volume":"72","author":"Fost","year":"1968","journal-title":"J Pediatr"},{"issue":"2","key":"10.1016\/j.mehy.2009.06.015_bib11","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1097\/00006534-200208000-00032","article-title":"Vascular anomalies: hemangiomas","volume":"110","author":"Gampper","year":"2002","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.mehy.2009.06.015_bib12","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0022-3476(05)81844-X","article-title":"Treatment of childhood angiomatous diseases with recombinant interferon alfa-2a","volume":"118","author":"White","year":"1991","journal-title":"J Pediatr"},{"issue":"22","key":"10.1016\/j.mehy.2009.06.015_bib13","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1056\/NEJM199205283262203","article-title":"Interferon alfa-2a therapy for life-threatening hemangiomas of infancy","volume":"326","author":"Ezekowitz","year":"1992","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.mehy.2009.06.015_bib14","first-page":"23","article-title":"Angiogenesis research: guidelines for translation to clinical application","volume":"86","author":"Folkman","year":"2001","journal-title":"Thromb Haemost"},{"issue":"2","key":"10.1016\/j.mehy.2009.06.015_bib15","doi-asserted-by":"crossref","first-page":"29e","DOI":"10.1097\/01.prs.0000197134.72984.cb","article-title":"The pathogenesis of hemangiomas: a review","volume":"117","author":"Bauland","year":"2006","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.mehy.2009.06.015_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00006534-199901000-00001","article-title":"Proliferative hemangiomas: analysis of cytokine gene expression and angiogenesis","volume":"103","author":"Chang","year":"1999","journal-title":"Plast Reconstr Surg"},{"issue":"6","key":"10.1016\/j.mehy.2009.06.015_bib17","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1172\/JCI117241","article-title":"Cellular markers that distinguish the phases of hemangioma during infancy and childhood","volume":"93","author":"Takahashi","year":"1994","journal-title":"J Clin Invest"},{"issue":"22","key":"10.1016\/j.mehy.2009.06.015_bib18","first-page":"6538","article-title":"Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats","volume":"62","author":"Fournier","year":"2002","journal-title":"Cancer Res"},{"issue":"3","key":"10.1016\/j.mehy.2009.06.015_bib19","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1124\/jpet.102.035295","article-title":"Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid","volume":"302","author":"Wood","year":"2002","journal-title":"J Pharmacol Exp Ther"},{"issue":"12","key":"10.1016\/j.mehy.2009.06.015_bib20","doi-asserted-by":"crossref","first-page":"5716","DOI":"10.1167\/iovs.07-1023","article-title":"Antiangiogenic effects of bisphosphonates on laser-induced choroidal neovascularization in mice","volume":"48","author":"Nagai","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"10.1016\/j.mehy.2009.06.015_bib21","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1177\/154405910708601005","article-title":"Angiogenesis inhibitors and the need for anti-angiogenic therapeutics","volume":"86","author":"Dass","year":"2007","journal-title":"J Dent Res"},{"issue":"8141","key":"10.1016\/j.mehy.2009.06.015_bib22","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0140-6736(79)91551-4","article-title":"Effects of disodium dichloromethylene diphosphonate on Paget\u2019s disease of bone","volume":"2","author":"Meunier","year":"1979","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.mehy.2009.06.015_bib23","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1210\/jcem-54-4-837","article-title":"Long term effects of dichloromethylene diphosphonate in Paget\u2019s disease of bone","volume":"54","author":"Delmas","year":"1982","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.mehy.2009.06.015_bib24","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.bbrc.2007.01.014","article-title":"Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells","volume":"354","author":"Hashimoto","year":"2007","journal-title":"Biochem Biophys Res Commun"},{"issue":"44","key":"10.1016\/j.mehy.2009.06.015_bib25","doi-asserted-by":"crossref","first-page":"43603","DOI":"10.1074\/jbc.M308114200","article-title":"Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death: evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B\/Akt","volume":"278","author":"Bezzi","year":"2003","journal-title":"J Biol Chem"},{"issue":"4","key":"10.1016\/j.mehy.2009.06.015_bib26","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1359\/jbmr.1998.13.4.581","article-title":"Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras","volume":"13","author":"Luckman","year":"1998","journal-title":"J Bone Miner Res"},{"issue":"5","key":"10.1016\/j.mehy.2009.06.015_bib27","first-page":"1080","article-title":"Pamidronate induces modifications of circulating angiogenetic factors in cancer patients","volume":"8","author":"Santini","year":"2002","journal-title":"Clin Cancer Res"},{"issue":"5","key":"10.1016\/j.mehy.2009.06.015_bib28","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1093\/annonc\/mdg194","article-title":"Bisphosphonates: new antiangiogenic molecules in cancer treatment?","volume":"4","author":"Vincenzi","year":"2003","journal-title":"Ann Oncol"},{"issue":"1","key":"10.1016\/j.mehy.2009.06.015_bib29","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1159\/000087286","article-title":"Zoledronic-acid-induced circulating level modifications of angiogenic factors, metalloproteinases and proinflammatory cytokines in metastatic breast cancer patients","volume":"69","author":"Ferretti","year":"2005","journal-title":"Oncology"},{"key":"10.1016\/j.mehy.2009.06.015_bib30","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1196\/annals.1365.036","article-title":"Bisphosphonates","volume":"1092","author":"Lambrinoudaki","year":"2006","journal-title":"Ann N Y Acad Sci"},{"issue":"1 Pt 1","key":"10.1016\/j.mehy.2009.06.015_bib31","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.1600-0765.1997.tb01380.x","article-title":"Net-shaped hydroxyapatite implants for release of agents modulating periodontal-like tissues","volume":"32","author":"Denissen","year":"1997","journal-title":"J Periodontal Res"},{"issue":"18","key":"10.1016\/j.mehy.2009.06.015_bib32","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/0142-9612(95)00342-8","article-title":"Clinical and histologic aspects of biphasic calcium phosphate ceramic (BCP) used in connection with implant placement","volume":"17","author":"Piattelli","year":"1996","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.mehy.2009.06.015_bib33","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/jbm.a.31989","article-title":"Controlled release of bisphosphonate from a calcium phosphate biomaterial inhibits osteoclastic resorption in vitro","volume":"89","author":"Faucheux","year":"2009","journal-title":"J Biomed Mater Res A"},{"issue":"14","key":"10.1016\/j.mehy.2009.06.015_bib34","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/j.biomaterials.2004.05.019","article-title":"Novel biomaterials for bisphosphonate delivery","volume":"26","author":"Josse","year":"2005","journal-title":"Biomaterials"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030698770900437X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030698770900437X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T12:25:08Z","timestamp":1558441508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030698770900437X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S030698770900437X"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2009.06.015","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]}}}