{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T19:51:13Z","timestamp":1648583473717},"reference-count":96,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.mehy.2009.09.045","type":"journal-article","created":{"date-parts":[[2009,10,28]],"date-time":"2009-10-28T08:26:11Z","timestamp":1256718371000},"page":"547-551","source":"Crossref","is-referenced-by-count":1,"title":["Do monoamine-synthesizing cells constitute a complex network of oxygen sensors?"],"prefix":"10.1016","volume":"74","author":[{"given":"K.","family":"Ondicova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Mravec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2009.09.045_bib1","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1152\/physrev.1996.76.3.839","article-title":"Oxygen sensing and molecular adaptation to hypoxia","volume":"76","author":"Bunn","year":"1996","journal-title":"Physiol Rev"},{"key":"10.1016\/j.mehy.2009.09.045_bib2","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0301-0082(99)00008-8","article-title":"CO2, brainstem chemoreceptors and breathing","volume":"59","author":"Nattie","year":"1999","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0034-5687(01)00290-0","article-title":"Monoaminergic neurons, chemosensation and arousal","volume":"129","author":"Haxhiu","year":"2001","journal-title":"Respir Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib4","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1146\/annurev.neuro.26.041002.131103","article-title":"Breathing: rhythmicity, plasticity, chemosensitivity","volume":"26","author":"Feldman","year":"2003","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.autneu.2005.04.005","article-title":"A new focus on interoceptive properties of adrenal medulla","volume":"120","author":"Mravec","year":"2005","journal-title":"Auton Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/PL00008810","article-title":"Molecular markers of sympathoadrenal cells","volume":"298","author":"Langley","year":"1999","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4067\/S0716-97602004000100002","article-title":"Recent advances in chromaffin cell biology: summing up the last International Symposium on Chromaffin Cell Biology","volume":"37","author":"Cardenas","year":"2004","journal-title":"Biol Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib8","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1152\/jappl.2000.88.6.2287","article-title":"Oxygen sensing by the carotid body chemoreceptors","volume":"88","author":"Prabhakar","year":"2000","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib9","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1152\/japplphysiol.00809.2003","article-title":"Peripheral chemoreceptors in health and disease","volume":"96","author":"Prabhakar","year":"2004","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib10","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1152\/physrev.1994.74.4.829","article-title":"Carotid body chemoreceptors: from natural stimuli to sensory discharges","volume":"74","author":"Gonzalez","year":"1994","journal-title":"Physiol Rev"},{"key":"10.1016\/j.mehy.2009.09.045_bib11","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/nrn1408","article-title":"HIF1 and oxygen sensing in the brain","volume":"5","author":"Sharp","year":"2004","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib12","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1152\/japplphysiol.00929.2003","article-title":"Regulation of oxygen sensing by ion channels","volume":"96","author":"Lopez-Barneo","year":"2004","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF00414167","article-title":"Immunohistochemical and histochemical evidence for the presence of noradrenaline, serotonin and gamma-aminobutyric acid in chief cells of the mouse carotid body","volume":"278","author":"Oomori","year":"1994","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.autneu.2005.04.008","article-title":"Neurotransmission and neuromodulation in the chemosensory carotid body","volume":"120","author":"Nurse","year":"2005","journal-title":"Auton Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib15","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.pbiomolbio.2005.07.001","article-title":"Oxygen sensing in the body","volume":"91","author":"Lahiri","year":"2006","journal-title":"Prog Biophys Mol Biol"},{"key":"10.1016\/j.mehy.2009.09.045_bib16","series-title":"Autonomic nervous system in health and disease","first-page":"23","article-title":"Overview of the autonomic nervous system","author":"Goldstein","year":"2001"},{"key":"10.1016\/j.mehy.2009.09.045_bib17","first-page":"H924","article-title":"Acute hypoxemia and hypercapnia: increase in plasma catecholamines in conscious dogs","volume":"245","author":"Rose","year":"1983","journal-title":"Am J Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib18","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1748-1716.1958.tb01596.x","article-title":"The release of catechol amines from the amine containing granules of the adrenal medulla","volume":"43","author":"Hillarp","year":"1958","journal-title":"Acta Physiol Scand"},{"key":"10.1016\/j.mehy.2009.09.045_bib19","doi-asserted-by":"crossref","first-page":"511","DOI":"10.2170\/jjphysiol.39.511","article-title":"Hypoxia and hypercapnia increase the sympathoadrenal medullary functions in anesthetized, artificially ventilated rats","volume":"39","author":"Biesold","year":"1989","journal-title":"Jpn J Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib20","first-page":"289","article-title":"Stress associated with adrenomedullary activation","author":"Goldstein","year":"1995"},{"key":"10.1016\/j.mehy.2009.09.045_bib21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0361-9230(86)90005-5","article-title":"Ontogeny of adrenomedullary responses to hypoxia and hypoglycemia: role of splanchnic innervation","volume":"16","author":"Seidler","year":"1986","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.mehy.2009.09.045_bib22","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1046\/j.1471-4159.1997.69010377.x","article-title":"Hypoxia-induced catecholamine release and intracellular Ca2+ increase via suppression of K+ channels in cultured rat adrenal chromaffin cells","volume":"69","author":"Mochizuki-Oda","year":"1997","journal-title":"J Neurochem"},{"key":"10.1016\/j.mehy.2009.09.045_bib23","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1006\/bbrc.2001.5913","article-title":"Nonneurogenic hypoxia sensitivity in rat adrenal slices","volume":"289","author":"Takeuchi","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.mehy.2009.09.045_bib24","first-page":"R1340","article-title":"Fetal adrenal medulla catecholamine response to hypoxia-direct and neural components","volume":"258","author":"Cheung","year":"1990","journal-title":"Am J Physiol"},{"issue":"Pt. 3","key":"10.1016\/j.mehy.2009.09.045_bib25","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1469-7793.1999.0765n.x","article-title":"Acid-evoked quantal catecholamine secretion from rat phaeochromocytoma cells and its interaction with hypoxia-evoked secretion","volume":"519","author":"Taylor","year":"1999","journal-title":"J Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib26","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1748-1716.1992.tb09300.x","article-title":"Reflex changes in post- and preganglionic sympathetic adrenal nerve activity and postganglionic sympathetic renal nerve activity upon arterial baroreceptor activation and during severe haemorrhage in the rat","volume":"144","author":"Carlsson","year":"1992","journal-title":"Acta Physiol Scand"},{"key":"10.1016\/j.mehy.2009.09.045_bib27","first-page":"R995","article-title":"Differential arterial baroreflex regulation of renal, lumbar, and adrenal sympathetic nerve activity in the rat","volume":"275","author":"Scislo","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib28","doi-asserted-by":"crossref","first-page":"R1763","DOI":"10.1152\/ajpregu.2000.279.5.R1763","article-title":"Different adrenal sympathetic preganglionic neurons regulate epinephrine and norepinephrine secretion","volume":"279","author":"Morrison","year":"2000","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib29","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1210\/endo-119-1-159","article-title":"Elevation in plasma catecholamines in response to insulin stress is under both neuronal and nonneuronal control","volume":"119","author":"Khalil","year":"1986","journal-title":"Endocrinology"},{"issue":"Pt. 2","key":"10.1016\/j.mehy.2009.09.045_bib30","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1113\/jphysiol.1997.sp021876","article-title":"Developmental loss of hypoxic chemosensitivity in rat adrenomedullary chromaffin cells","volume":"498","author":"Thompson","year":"1997","journal-title":"J Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib31","first-page":"51","article-title":"The innervation of the adrenal gland. II. The source of spinal afferent nerve fibres to the guinea-pig adrenal gland","volume":"160","author":"Mohamed","year":"1988","journal-title":"J Anat"},{"key":"10.1016\/j.mehy.2009.09.045_bib32","first-page":"173","article-title":"The innervation of the adrenal gland. III. Vagal innervation","volume":"163","author":"Coupland","year":"1989","journal-title":"J Anat"},{"key":"10.1016\/j.mehy.2009.09.045_bib33","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0165-1838(91)90025-X","article-title":"Substance P-containing sensory neurons in the rat dorsal root ganglia innervate the adrenal medulla","volume":"33","author":"Zhou","year":"1991","journal-title":"J Auton Nerv Syst"},{"key":"10.1016\/j.mehy.2009.09.045_bib34","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/0306-4522(95)00305-3","article-title":"Adrenal medullary ganglion neurons project into the splanchnic nerve","volume":"69","author":"Dagerlind","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.mehy.2009.09.045_bib35","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/BF00300702","article-title":"Chemical codes of sensory neurons innervating the guinea-pig adrenal gland","volume":"279","author":"Heym","year":"1995","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib36","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1172\/JCI118916","article-title":"An intrinsic adrenergic system in mammalian heart","volume":"98","author":"Huang","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1016\/j.mehy.2009.09.045_bib37","doi-asserted-by":"crossref","first-page":"H497","DOI":"10.1152\/ajpheart.00591.2004","article-title":"Neuroendocrine properties of intrinsic cardiac adrenergic cells in fetal rat heart","volume":"288","author":"Huang","year":"2005","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib38","first-page":"1","article-title":"Basophils and mast cells: morphologic insights into their biology, secretory patterns, and function","volume":"34","author":"Galli","year":"1984","journal-title":"Prog Allergy"},{"key":"10.1016\/j.mehy.2009.09.045_bib39","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1152\/japplphysiol.00637.2002","article-title":"Mast cells mediate the microvascular inflammatory response to systemic hypoxia","volume":"94","author":"Steiner","year":"2003","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib40","first-page":"G316","article-title":"Mast cells contribute to ischemia-reperfusion-induced granulocyte infiltration and intestinal dysfunction","volume":"267","author":"Kanwar","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib41","first-page":"R906","article-title":"Histamine-sensitive intrinsic cardiac and intrathoracic extracardiac neurons influence cardiodynamics","volume":"270","author":"Armour","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib42","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1006\/jmcc.1996.0034","article-title":"Lack of evidence for a role of mast cell degranulation in acute hypoxia\/reoxygenation-induced injury in the isolated rat heart","volume":"28","author":"van Haaster","year":"1996","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib43","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/00005344-198205000-00015","article-title":"Effects of lodoxamide on ischemic reperfused myocardium","volume":"4","author":"Jolly","year":"1982","journal-title":"J Cardiovasc Pharmacol"},{"issue":"Suppl. C","key":"10.1016\/j.mehy.2009.09.045_bib44","first-page":"30","article-title":"Role of histamine H3 receptor on hypoxia-reoxygenation-induced cardiac dysfunction in guinea pigs","volume":"17","author":"Akagi","year":"1995","journal-title":"Methods Find Exp Clin Pharmacol"},{"key":"10.1016\/j.mehy.2009.09.045_bib45","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/0049-3848(90)90153-4","article-title":"Influence of hypercapnia and hypoxia on rabbit platelet aggregation","volume":"57","author":"oude Egbrink","year":"1990","journal-title":"Thromb Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0014-2999(02)02734-6","article-title":"5-Hydroxytryptamine and platelets: uptake and aggregation in hypoxic pulmonary hypertensive rats","volume":"459","author":"Awabdy","year":"2003","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.mehy.2009.09.045_bib47","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1152\/japplphysiol.00831.2003","article-title":"Oxygen-sensing neurons in the central nervous system","volume":"96","author":"Neubauer","year":"2004","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib48","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1177\/02698811030173002","article-title":"Does the brain noradrenaline network mediate the effects of the CO2 challenge?","volume":"17","author":"Bailey","year":"2003","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.mehy.2009.09.045_bib49","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1177\/0269881105053281","article-title":"Acute hypercarbic gas exposure reveals functionally distinct subpopulations of serotonergic neurons in rats","volume":"19","author":"Johnson","year":"2005","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.mehy.2009.09.045_bib50","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/cne.903480202","article-title":"Hypoxia and electrical stimulation of the carotid sinus nerve induce Fos-like immunoreactivity within catecholaminergic and serotoninergic neurons of the rat brainstem","volume":"348","author":"Erickson","year":"1994","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.mehy.2009.09.045_bib51","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0034-5687(02)00012-9","article-title":"Neurochemical perspectives on the control of breathing during sleep","volume":"130","author":"Joseph","year":"2002","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib52","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1046\/j.0953-816x.2001.01816.x","article-title":"Selective cardiorespiratory and catecholaminergic areas express the hypoxia-inducible factor-1alpha (HIF-1alpha) under in vivo hypoxia in rat brainstem","volume":"14","author":"Pascual","year":"2001","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib53","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/0306-4522(96)00051-6","article-title":"Comparison of neurons in rat medulla oblongata with fos immunoreactivity evoked by seizures, chemoreceptor, or baroreceptor stimulation","volume":"73","author":"Kanter","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.mehy.2009.09.045_bib54","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1046\/j.1460-9568.2000.00208.x","article-title":"O2-sensing after carotid chemodenervation: hypoxic ventilatory responsiveness and upregulation of tyrosine hydroxylase mRNA in brainstem catecholaminergic cells","volume":"12","author":"Roux","year":"2000","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib55","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0034-5687(96)00034-5","article-title":"CO2-induced c-fos expression in the CNS catecholaminergic neurons","volume":"105","author":"Haxhiu","year":"1996","journal-title":"Respir Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib56","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1152\/physrev.1994.74.2.323","article-title":"Functional organization of central pathways regulating the cardiovascular system","volume":"74","author":"Dampney","year":"1994","journal-title":"Physiol Rev"},{"key":"10.1016\/j.mehy.2009.09.045_bib57","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.pneurobio.2003.11.001","article-title":"Functional organisation of central cardiovascular pathways: studies using c-fos gene expression","volume":"71","author":"Dampney","year":"2003","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib58","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/nn848","article-title":"Chemosensitive serotonergic neurons are closely associated with large medullary arteries","volume":"5","author":"Bradley","year":"2002","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib59","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1038\/nn1130","article-title":"Midbrain serotonergic neurons are central pH chemoreceptors","volume":"6","author":"Severson","year":"2003","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib60","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nrn1409","article-title":"Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis","volume":"5","author":"Richerson","year":"2004","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib61","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/nn0502-396","article-title":"Putative chemoreceptors get close to arteries","volume":"5","author":"Fiske","year":"2002","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib62","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0361-9230(01)00612-8","article-title":"Central cardiovascular regulation and 5-hydroxytryptamine receptors","volume":"56","author":"Ramage","year":"2001","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.mehy.2009.09.045_bib63","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0034-5687(01)00289-4","article-title":"Chemosensitivity of serotonergic neurons in the rostral ventral medulla","volume":"129","author":"Richerson","year":"2001","journal-title":"Respir Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib64","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0006-8993(99)02304-5","article-title":"Brainstem and hypothalamic areas involved in respiratory chemoreflexes: a Fos study in adult rats","volume":"857","author":"Berquin","year":"2000","journal-title":"Brain Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib65","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.expneurol.2004.11.022","article-title":"Are tuberomammillary histaminergic neurons involved in CO2-mediated arousal?","volume":"193","author":"Johnson","year":"2005","journal-title":"Exp Neurol"},{"key":"10.1016\/j.mehy.2009.09.045_bib66","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1007\/s00424-002-0904-z","article-title":"Histaminergic modulation of the intact respiratory network of adult mice","volume":"445","author":"Dutschmann","year":"2003","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.mehy.2009.09.045_bib67","first-page":"100","article-title":"Central neuronal histamine contributes to cardiovascular regulation","volume":"14","author":"Bealer","year":"1999","journal-title":"News Physiol Sci"},{"key":"10.1016\/j.mehy.2009.09.045_bib68","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.brainresbull.2004.09.009","article-title":"A role for the central histaminergic system in the leptin-mediated increase in cardiovascular dynamics","volume":"64","author":"Rao","year":"2005","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.mehy.2009.09.045_bib69","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/BF00641050","article-title":"The brain as a self-organizing system","volume":"236","author":"Singer","year":"1986","journal-title":"Eur Arch Psychiat Neurol Sci"},{"key":"10.1016\/j.mehy.2009.09.045_bib70","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0079-6123(08)63807-8","article-title":"Developmental aspects of the locus coeruleus-noradrenaline system","volume":"88","author":"Marshall","year":"1991","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib71","first-page":"323","article-title":"Developmental regulation of spinal motoneurons by monoaminergic nerve fibers","volume":"2","author":"Tanaka","year":"1997","journal-title":"J Peripher Nerv Syst"},{"key":"10.1016\/j.mehy.2009.09.045_bib72","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0306-4522(02)00026-X","article-title":"Neuromodulatory transmitter systems in the cortex and their role in cortical plasticity","volume":"111","author":"Gu","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.mehy.2009.09.045_bib73","doi-asserted-by":"crossref","first-page":"5212","DOI":"10.1523\/JNEUROSCI.21-14-05212.2001","article-title":"Altered respiratory activity and respiratory regulations in adult monoamine oxidase A-deficient mice","volume":"21","author":"Burnet","year":"2001","journal-title":"J Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0300-9629(96)00369-6","article-title":"Peripheral chemosensitivity and central integration: neuroplasticity of catecholaminergic cells under hypoxia","volume":"118","author":"Soulier","year":"1997","journal-title":"Comp Biochem Physiol A Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib75","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/cne.903010409","article-title":"An intracellular study of respiratory neurons in the rostral ventrolateral medulla of the rat and their relationship to catecholamine-containing neurons","volume":"301","author":"Pilowsky","year":"1990","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.mehy.2009.09.045_bib76","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/0-387-27023-X_9","article-title":"Chemosensory inputs and neural remodeling in carotid body and brainstem catecholaminergic cells","volume":"551","author":"Soulage","year":"2004","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.mehy.2009.09.045_bib77","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0304-3940(99)00249-9","article-title":"Characterization of pontine neurons which respond to hypoxia in fetal sheep","volume":"266","author":"Nitsos","year":"1999","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.mehy.2009.09.045_bib78","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1046\/j.1440-1681.2000.03201.x","article-title":"Effect of hypoxia on respiratory activity in the foetus","volume":"27","author":"Walker","year":"2000","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib79","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1196\/annals.1410.008","article-title":"Catecholamine-synthesizing cells in the embryonic mouse heart","volume":"1148","author":"Ebert","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.mehy.2009.09.045_bib80","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1203\/01.PDR.0000081760.48331.7A","article-title":"Neurodegeneration, neuronal loss, and neurotransmitter changes in the adult guinea pig with perinatal asphyxia","volume":"54","author":"Bernert","year":"2003","journal-title":"Pediatr Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib81","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/syn.20065","article-title":"Long-term prenatal hypoxia alters maturation of brain catecholaminergic systems and motor behavior in rats","volume":"54","author":"Perrin","year":"2004","journal-title":"Synapse"},{"key":"10.1016\/j.mehy.2009.09.045_bib82","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1203\/00006450-199710000-00006","article-title":"Effects of chronic prenatal hypoxia on tyrosine hydroxylase and phenylethanolamine N-methyltransferase messenger RNA and protein levels in medulla oblongata of postnatal rat","volume":"42","author":"White","year":"1997","journal-title":"Pediatr Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib83","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1542\/peds.101.2.285","article-title":"Catecholamine neurons alteration in the brainstem of sudden infant death syndrome victims","volume":"101","author":"Obonai","year":"1998","journal-title":"Pediatrics"},{"key":"10.1016\/j.mehy.2009.09.045_bib84","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0887-8994(99)00033-8","article-title":"Catecholaminergic neurons in the diencephalon and basal ganglia of SIDS","volume":"21","author":"Ozawa","year":"1999","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.mehy.2009.09.045_bib85","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1203\/00006450-200202000-00014","article-title":"Long-term prenatal hypoxia alters maturation of adrenal medulla in rat","volume":"51","author":"Mamet","year":"2002","journal-title":"Pediatr Res"},{"key":"10.1016\/j.mehy.2009.09.045_bib86","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/S0022-3476(00)90008-8","article-title":"Hyper-releasability of mast cells in family members of infants with sudden infant death syndrome and apparent life-threatening events","volume":"136","author":"Gold","year":"2000","journal-title":"J Pediatr"},{"key":"10.1016\/j.mehy.2009.09.045_bib87","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1046\/j.1365-2222.2001.01237.x","article-title":"Light is recognized best through darkness: mast cells and Sudden Infant Death Syndrome","volume":"31","author":"Schwartz","year":"2001","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.mehy.2009.09.045_bib88","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/1096-911X(20010101)36:1<149::AID-MPO1036>3.0.CO;2-M","article-title":"Evidence of chromaffin oxygen sensing in neuroblastoma","volume":"36","author":"Hedborg","year":"2001","journal-title":"Med Pediatr Oncol"},{"key":"10.1016\/j.mehy.2009.09.045_bib89","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1096\/fj.02-0390com","article-title":"Evidence for hypoxia-induced neuronal-to-chromaffin metaplasia in neuroblastoma","volume":"17","author":"Hedborg","year":"2003","journal-title":"FASEB J"},{"issue":"Suppl. 3","key":"10.1016\/j.mehy.2009.09.045_bib90","first-page":"107","article-title":"The aging carotid body","volume":"55","author":"Pokorski","year":"2004","journal-title":"J Physiol Pharmacol"},{"key":"10.1016\/j.mehy.2009.09.045_bib91","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1152\/jappl.2000.88.6.2296","article-title":"Developmental aspects of oxygen sensing by the carotid body","volume":"88","author":"Donnelly","year":"2000","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib92","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/j.1469-7793.2000.00407.x","article-title":"Human ageing and the sympathoadrenal system","volume":"528","author":"Seals","year":"2000","journal-title":"J Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib93","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.1242\/jeb.01075","article-title":"Cellular oxygen sensing need in CNS function: physiological and pathological implications","volume":"207","author":"Acker","year":"2004","journal-title":"J Exp Biol"},{"key":"10.1016\/j.mehy.2009.09.045_bib94","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/nrn871","article-title":"Specification of catecholaminergic and serotonergic neurons","volume":"3","author":"Goridis","year":"2002","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.mehy.2009.09.045_bib95","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0034-5687(01)00297-3","article-title":"Central chemosensitivity of respiration: a brief overview","volume":"129","author":"Ballantyne","year":"2001","journal-title":"Respir Physiol"},{"key":"10.1016\/j.mehy.2009.09.045_bib96","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0034-5687(01)00295-X","article-title":"Central chemosensitivity, sleep, and wakefulness","volume":"129","author":"Nattie","year":"2001","journal-title":"Respir Physiol"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987709006641?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987709006641?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T12:01:20Z","timestamp":1558612880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987709006641"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":96,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0306987709006641"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2009.09.045","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}