{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T15:02:58Z","timestamp":1793286178749,"version":"4.5.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.mehy.2010.04.021","type":"journal-article","created":{"date-parts":[[2010,5,8]],"date-time":"2010-05-08T09:16:46Z","timestamp":1273310206000},"page":"448-451","source":"Crossref","is-referenced-by-count":9,"title":["Self-fertilization in human: Having a male embryo without a father"],"prefix":"10.1016","volume":"75","author":[{"given":"M. Kemal","family":"Irmak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2010.04.021_bib1","series-title":"The developing human, clinically oriented embryology","author":"Moore","year":"2003"},{"key":"10.1016\/j.mehy.2010.04.021_bib2","doi-asserted-by":"crossref","first-page":"467","DOI":"10.2169\/internalmedicine.37.467","article-title":"A rare case of 46,XX true hermaphroditism with hidden mosaicism with sex-determining region Y chromosome-bearing cells in the gonads","volume":"37","author":"Inoue","year":"1998","journal-title":"Intern Med"},{"key":"10.1016\/j.mehy.2010.04.021_bib3","series-title":"Nelson textbook of pediatrics","author":"Behrman","year":"2004"},{"key":"10.1016\/j.mehy.2010.04.021_bib4","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/BF02000779","article-title":"True hermaphrodite: geographical distribution, clinical findings, chromosomes and gonadal histology","volume":"153","author":"Krob","year":"1994","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.mehy.2010.04.021_bib5","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF00284158","article-title":"The gonads of human true hermaphrodites","volume":"58","author":"van Niekerk","year":"1981","journal-title":"Hum Genet"},{"key":"10.1016\/j.mehy.2010.04.021_bib6","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1097\/00000658-195211000-00010","article-title":"True hermaphroditism","volume":"136","author":"Fischer","year":"1952","journal-title":"Ann Surg"},{"key":"10.1016\/j.mehy.2010.04.021_bib7","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1111\/j.1464-410X.1985.tb07052.x","article-title":"True hermaphroditism: a review of 41 cases with observations on testicular histology and function","volume":"57","author":"Aaronson","year":"1985","journal-title":"Br J Urol"},{"key":"10.1016\/j.mehy.2010.04.021_bib8","series-title":"Human molecular genetics","author":"Strachan","year":"2004"},{"key":"10.1016\/j.mehy.2010.04.021_bib9","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1399-0004.2006.00689.x","article-title":"Chimera and other fertilization errors","volume":"70","author":"Malan","year":"2006","journal-title":"Clin Genet"},{"key":"10.1016\/j.mehy.2010.04.021_bib10","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/AOG.0b013e3181866456","article-title":"Pregnancy in true hermaphrodites and all male offspring to date","volume":"113","author":"Schultz","year":"2009","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.mehy.2010.04.021_bib11","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/0002-9378(76)90677-3","article-title":"True hermaphroditism: an analytic review with a report of 3 new cases","volume":"126","author":"van Niekerk","year":"1976","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.mehy.2010.04.021_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.1998.78.1.1","article-title":"Regulation of sexual dimorphism in mammals","volume":"78","author":"Haqq","year":"1998","journal-title":"Physiol Rev"},{"key":"10.1016\/j.mehy.2010.04.021_bib13","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1159\/000463848","article-title":"Childbirth in true hermaphrodites","volume":"10","author":"Minowada","year":"1984","journal-title":"Eur Urol"},{"key":"10.1016\/j.mehy.2010.04.021_bib14","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0015-0282(16)57317-8","article-title":"Molecular biologic analyses of tetragametic chimerism in a true hermaphrodite with 46,XX\/46,XY","volume":"63","author":"Uehara","year":"1995","journal-title":"Fertil Steril"},{"key":"10.1016\/j.mehy.2010.04.021_bib15","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1136\/jmg.31.10.816","article-title":"Chimaerism shown by cytogenetics and DNA polymorphism analysis","volume":"31","author":"Green","year":"1994","journal-title":"J Med Genet"},{"key":"10.1016\/j.mehy.2010.04.021_bib16","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1159\/000056847","article-title":"SRY protein is expressed in ovotestis and streak gonads from human sex-reversal","volume":"91","author":"Salas-Cortes","year":"2000","journal-title":"Cytogenet Cell Genet"},{"key":"10.1016\/j.mehy.2010.04.021_bib17","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0022-3476(06)80172-1","article-title":"True hermaphroditism: genetic variants and clinical management","volume":"125","author":"Hadjiathanasiou","year":"1994","journal-title":"J Pediatr"},{"key":"10.1016\/j.mehy.2010.04.021_bib18","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1086\/301796","article-title":"Polymorphic detection of a parthenogenetic maternal and double paternal contribution to a 46,XX\/46,XY hermaphrodite","volume":"62","author":"Giltay","year":"1998","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.mehy.2010.04.021_bib19","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/BF00215684","article-title":"Mutational analysis of SRY: nonsense and missense mutations in XY sex reversal","volume":"88","author":"Hawkins","year":"1992","journal-title":"Hum Genet"},{"key":"10.1016\/j.mehy.2010.04.021_bib20","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/351117a0","article-title":"Male development of chromosomally female mice transgenic for Sry","volume":"351","author":"Koopman","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.mehy.2010.04.021_bib21","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1095\/biolreprod37.4.1015","article-title":"M\u00fcllerian inhibiting substance in sex-reversed dogs","volume":"37","author":"Meyers-Wallen","year":"1987","journal-title":"Biol Reprod"},{"key":"10.1016\/j.mehy.2010.04.021_bib22","doi-asserted-by":"crossref","first-page":"435","DOI":"10.2460\/javma.1991.198.03.435","article-title":"XX true hermaphroditism in a dog","volume":"198","author":"Sommer","year":"1991","journal-title":"J Am Vet Med Assoc"},{"issue":"Feb","key":"10.1016\/j.mehy.2010.04.021_bib23","first-page":"59","article-title":"Growth pattern of the sex ducts in foetal mouse hermaphrodites","volume":"73","author":"Andersen","year":"1983","journal-title":"J Embryol Exp Morphol"},{"key":"10.1016\/j.mehy.2010.04.021_bib24","first-page":"5","article-title":"The transperitoneal migration of ova in the rabbit","volume":"17","author":"McComb","year":"1986","journal-title":"Acta Eur Fertil"},{"key":"10.1016\/j.mehy.2010.04.021_bib25","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/j.1439-0442.1991.tb01038.x","article-title":"The effect of unilateral ovariectomy on intraluminal pressure in the porcine oviductal isthmus","volume":"38","author":"Pettersson","year":"1991","journal-title":"Zentralbl Veterinarmed A"},{"key":"10.1016\/j.mehy.2010.04.021_bib26","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0378-4320(00)00095-6","article-title":"Effects of post-ovulatory food deprivation on the hormonal profiles, activity of the oviduct and ova transport in sows","volume":"59","author":"Mwanza","year":"2000","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.mehy.2010.04.021_bib27","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/BF03548198","article-title":"Intraluminal pressure variations in the isthmus of the porcine oviduct after intrauterine insemination with saline, oestrogen solution or boar seminal plasma","volume":"34","author":"Pettersson","year":"1993","journal-title":"Acta Vet Scand"},{"key":"10.1016\/j.mehy.2010.04.021_bib28","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0378-4320(00)00123-8","article-title":"Oviductal isthmic motility patterns as monitored by polyview in unrestrained sows around ovulation","volume":"62","author":"Mwanza","year":"2000","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.mehy.2010.04.021_bib29","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S1472-6483(10)61738-5","article-title":"Intrauterine pregnancy following transperitoneal oocyte and\/or sperm migration in a woman with an ectopic (undescended) ovary","volume":"7","author":"Ombelet","year":"2003","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.mehy.2010.04.021_bib30","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0015-0282(16)55996-2","article-title":"Successive transperitoneal migration of ova in a woman with extensive pelvic adhesions","volume":"59","author":"Motta","year":"1993","journal-title":"Fertil Steril"},{"key":"10.1016\/j.mehy.2010.04.021_bib31","doi-asserted-by":"crossref","first-page":"665","DOI":"10.3109\/00016348809004285","article-title":"Transperitoneal ovum migration in women with unilateral congenital ovarian absence","volume":"67","author":"Ben-Nun","year":"1988","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.mehy.2010.04.021_bib32","first-page":"895","article-title":"Transperitoneal migration of the ovum. A case report","volume":"30","author":"Wheeler","year":"1985","journal-title":"J Reprod Med"},{"key":"10.1016\/j.mehy.2010.04.021_bib33","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1046\/j.0001-6349.2002.00001.x","article-title":"Unruptured pregnancy in a non-communicating heterotopic right fallopian tube associated with left unicornuate uterus: evidence for transperitoneal sperm and oocyte migration","volume":"81","author":"Gabriel","year":"2002","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.mehy.2010.04.021_bib34","first-page":"391","article-title":"Intrauterine pregnancy following transperitoneal migration of the ovum","volume":"60","author":"Kamrava","year":"1982","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.mehy.2010.04.021_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/01485019408987759","article-title":"Sperm transmigration as a cause of ectopic pregnancy","volume":"32","author":"Ansari","year":"1994","journal-title":"Arch Androl"},{"key":"10.1016\/j.mehy.2010.04.021_bib36","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S0002-9378(16)32630-8","article-title":"True hermaphroditism with term vaginal delivery and a review","volume":"141","author":"Williamson","year":"1981","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.mehy.2010.04.021_bib37","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1006\/gyno.2000.6004","article-title":"Pregnancy in a woman with a Y chromosome after removal of an ovarian dysgerminoma","volume":"79","author":"Tanaka","year":"2000","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.mehy.2010.04.021_bib38","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.1002\/1097-0142(19901215)66:12<2668::AID-CNCR2820661234>3.0.CO;2-5","article-title":"True hermaphrodite with bilateral ovotestis, bilateral gonadoblastomas and dysgerminomas, 46,XX\/46,XY karyotype, and a successful pregnancy","volume":"66","author":"Talerman","year":"1990","journal-title":"Cancer"},{"key":"10.1016\/j.mehy.2010.04.021_bib39","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S0015-0282(16)54843-2","article-title":"Chimerism as the etiology of a 46XX\/46XY fertile true hermaphrodite","volume":"57","author":"Verp","year":"1992","journal-title":"Fertil Steril"},{"key":"10.1016\/j.mehy.2010.04.021_bib40","first-page":"752","article-title":"Multiparity in a covert true hermaphrodite","volume":"60","author":"Tiltman","year":"1982","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.mehy.2010.04.021_bib41","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1471-0528.1978.tb10505.x","article-title":"Pregnancy and childbirth in a true hermaphrodite following reconstructive surgery","volume":"85","author":"Mayou","year":"1978","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.mehy.2010.04.021_bib42","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/0002-9378(79)90718-X","article-title":"Pregnancy without benefit of reconstructive surgery in a bisexually active true hermaphrodite","volume":"135","author":"Tegenkamp","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.mehy.2010.04.021_bib43","doi-asserted-by":"crossref","first-page":"E7","DOI":"10.1016\/j.fertnstert.2008.01.104","article-title":"Pregnancy in a hermaphrodite with a male-predominant mosaic karyotype","volume":"90","author":"Schoenhaus","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.mehy.2010.04.021_bib44","series-title":"Molecular biology of the cell","first-page":"1243","author":"Alberts","year":"2002"},{"key":"10.1016\/j.mehy.2010.04.021_bib45","first-page":"598","article-title":"A case of combined hermaphroditism and autofertilisation in a domestic rabbit","volume":"126","author":"Frankenhuis","year":"1990","journal-title":"Vet Rec"},{"key":"10.1016\/j.mehy.2010.04.021_bib46","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/dvg.20240","article-title":"Methyltestosterone efficiently induces male development in the self-fertilizing hermaphrodite fish, Kryptolebias marmoratus","volume":"44","author":"Kanamori","year":"2006","journal-title":"Genesis"},{"key":"10.1016\/j.mehy.2010.04.021_bib47","doi-asserted-by":"crossref","first-page":"9924","DOI":"10.1073\/pnas.0603847103","article-title":"Extensive outcrossing and androdioecy in a vertebrate species that otherwise reproduces as a self-fertilizing hermaphrodite","volume":"103","author":"Mackiewicz","year":"2006","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987710001957?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987710001957?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T16:19:07Z","timestamp":1711469947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987710001957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0306987710001957"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2010.04.021","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}