{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T10:30:51Z","timestamp":1772706651623,"version":"3.50.1"},"reference-count":14,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Nature Science Foundation of China","doi-asserted-by":"crossref","award":["81172012"],"award-info":[{"award-number":["81172012"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["medical-hypotheses.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.mehy.2013.08.002","type":"journal-article","created":{"date-parts":[[2013,8,11]],"date-time":"2013-08-11T08:31:16Z","timestamp":1376209876000},"page":"851-852","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Postoperative irrigation with bisphosphonates may reduce the recurrence of giant cell tumor of bone"],"prefix":"10.1016","volume":"81","author":[{"given":"Tao","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Fei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-Shui","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.mehy.2013.08.002_b0005","doi-asserted-by":"crossref","first-page":"118","DOI":"10.5435\/JAAOS-21-02-118","article-title":"Giant cell tumor of bone","volume":"21","author":"Raskin","year":"2013","journal-title":"J Am Acad Orthop Surg"},{"issue":"1","key":"10.1016\/j.mehy.2013.08.002_b0010","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.bone.2012.10.002","article-title":"Giant cell tumor of bone: a basic science perspective","volume":"52","author":"Cowan","year":"2013","journal-title":"Bone"},{"issue":"3","key":"10.1016\/j.mehy.2013.08.002_b0015","first-page":"207","article-title":"Giant cell tumor (tumor gigantocellularis, osteoclastoma) \u2013 epidemiology, diagnosis, treatment","volume":"12","author":"Karpik","year":"2010","journal-title":"Ortop Traumatol Rehabil"},{"key":"10.1016\/j.mehy.2013.08.002_b0020","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/01.blo.0000160024.06739.ff","article-title":"Does curettage without adjuvant therapy provide low recurrence rates in giant-cell tumors of bone","volume":"435","author":"Prosser","year":"2005","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"10.1016\/j.mehy.2013.08.002_b0025","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4103\/0019-5413.32039","article-title":"Treatment of giant cell tumor of bone: current concepts","volume":"41","author":"Puri","year":"2007","journal-title":"Indian J Orthop"},{"issue":"10","key":"10.1016\/j.mehy.2013.08.002_b0030","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1302\/0301-620X.92B10.23495","article-title":"The efficacy of chemical adjuvants on giant-cell tumour of bone. An in vitro study","volume":"92","author":"Gortzak","year":"2010","journal-title":"J Bone Joint Surg Br"},{"issue":"11","key":"10.1016\/j.mehy.2013.08.002_b0035","first-page":"2949","article-title":"Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases","volume":"60","author":"Boissier","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.mehy.2013.08.002_b0040","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/01.blo.0000141372.54456.80","article-title":"Bisphosphonates may reduce recurrence in giant cell tumor by inducing apoptosis","volume":"426","author":"Chang","year":"2004","journal-title":"Clin Orthop Relat Res"},{"issue":"1","key":"10.1016\/j.mehy.2013.08.002_b0045","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.bone.2007.08.038","article-title":"Bisphosphonates reduce local recurrence in extremity giant cell tumor of bone: a case-control study","volume":"42","author":"Tse","year":"2008","journal-title":"Bone"},{"issue":"3","key":"10.1016\/j.mehy.2013.08.002_b0065","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.bone.2003.10.013","article-title":"Expression of preosteoblast markers and Cbfa-1 and Osterix gene transcripts in stromal tumour cells of giant cell tumour of bone","volume":"34","author":"Huang","year":"2004","journal-title":"Bone"},{"issue":"33","key":"10.1016\/j.mehy.2013.08.002_b0070","doi-asserted-by":"crossref","first-page":"8674","DOI":"10.1016\/j.biomaterials.2010.07.096","article-title":"The effect of the local delivery of alendronate on human adipose-derived stem cell-based bone regeneration","volume":"31","author":"Wang","year":"2010","journal-title":"Biomaterials"},{"issue":"8","key":"10.1016\/j.mehy.2013.08.002_b0050","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1007\/s00520-010-0882-1","article-title":"A systematic review of bisphosphonate osteonecrosis (BON) in cancer","volume":"18","author":"Migliorati","year":"2010","journal-title":"Support Care Cancer"},{"issue":"13","key":"10.1016\/j.mehy.2013.08.002_b0055","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1001\/jama.2010.1360","article-title":"Atypical fractures as a potential complication of long-term bisphosphonate therapy","volume":"304","author":"Sellmeyer","year":"2010","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.mehy.2013.08.002_b0060","doi-asserted-by":"crossref","first-page":"e312","DOI":"10.3928\/01477447-20110526-22","article-title":"Locally administered zoledronic acid therapy for giant cell tumor of bone","volume":"34","author":"Nishisho","year":"2011","journal-title":"Orthopedics"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987713003915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987713003915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T14:54:16Z","timestamp":1646319256000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987713003915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0306987713003915"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2013.08.002","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Postoperative irrigation with bisphosphonates may reduce the recurrence of giant cell tumor of bone","name":"articletitle","label":"Article Title"},{"value":"Medical Hypotheses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mehy.2013.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}