{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T00:40:38Z","timestamp":1688517638171},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["medical-hypotheses.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.mehy.2013.09.030","type":"journal-article","created":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T18:32:37Z","timestamp":1380652357000},"page":"1155-1158","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["The role of erythropoietin and erythropoietin receptor in malignant laryngeal tumors"],"prefix":"10.1016","volume":"81","author":[{"given":"Jelena","family":"Vukelic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata","family":"Dobrila-Dintinjana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nives","family":"Jonjic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Dekanic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vjekoslav","family":"Ilijic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.mehy.2013.09.030_b0005","doi-asserted-by":"crossref","first-page":"649","DOI":"10.2169\/internalmedicine.43.649","article-title":"Molecular biology of erythropoietin","volume":"43","author":"Jelkmann","year":"2004","journal-title":"Intern Med"},{"issue":"2","key":"10.1016\/j.mehy.2013.09.030_b0010","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1158\/1078-0432.CCR-05-1771","article-title":"Erythropoietin biology in cancer","volume":"12","author":"Hardee","year":"2006","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.mehy.2013.09.030_b0015","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/ki.1997.52","article-title":"Sites of erythropoietin production","volume":"51","author":"Maxwell","year":"1997","journal-title":"Kidney Int"},{"key":"10.1016\/j.mehy.2013.09.030_b0020","doi-asserted-by":"crossref","first-page":"7819","DOI":"10.1073\/pnas.86.20.7819","article-title":"Relationship between sugar chain structure and biological activity of recombinant human erythropoietin produced in Chinese hamster ovary cells","volume":"86","author":"Takeuchi","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"10.1016\/j.mehy.2013.09.030_b0025","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1182\/blood.V76.1.24.24","article-title":"The gene for the human erythropoietin receptor: analysis of the coding sequence and assignment to chromosome 19p","volume":"76","author":"Winkelmann","year":"1990","journal-title":"Blood"},{"issue":"29","key":"10.1016\/j.mehy.2013.09.030_b0030","doi-asserted-by":"crossref","first-page":"26547","DOI":"10.1074\/jbc.M202287200","article-title":"A functional green fluorescent protein-erythropoietin receptor despite physical separation of JAK2 binding site and tyrosine residues","volume":"277","author":"Ketteler","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mehy.2013.09.030_b0035","first-page":"163","article-title":"The effect of erythropoietin on normal and neoplastic cells","volume":"6","author":"Elliott","year":"2012","journal-title":"Biologics"},{"key":"10.1016\/j.mehy.2013.09.030_b0040","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1002\/1097-0142(20010615)91:12<2214::AID-CNCR1251>3.0.CO;2-P","article-title":"Anemia as an independent prognostic factor for survival in patients with cancer: a systemic, quantitative review","volume":"91","author":"Caro","year":"2001","journal-title":"Cancer"},{"issue":"5","key":"10.1016\/j.mehy.2013.09.030_b0045","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1593\/neo.04685","article-title":"Erythropoietin signaling promotes invasiveness of human head and neck squamous cell carcinoma","volume":"7","author":"Mohyeldin","year":"2005","journal-title":"Neoplasia"},{"key":"10.1016\/j.mehy.2013.09.030_b0050","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0002-9440(10)64314-3","article-title":"Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression","volume":"162","author":"Acs","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.mehy.2013.09.030_b0055","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1002\/cncr.10787","article-title":"Immunohistochemical expression of erythropoietin and erythropoietin receptor in breast carcinoma","volume":"95","author":"Acs","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.mehy.2013.09.030_b0060","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1002\/cncr.20244","article-title":"Prognostic significance of erythropoietin expression in human endometrial carcinoma","volume":"100","author":"Acs","year":"2004","journal-title":"Cancer"},{"key":"10.1016\/j.mehy.2013.09.030_b0065","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1097\/00005537-200403000-00006","article-title":"Dysregulation of hypoxia inducible factor-1alpha in head and neck squamous cell carcinoma cell lines correlates with invasive potential","volume":"11","author":"Cohen","year":"2004","journal-title":"Laryngoscope"},{"key":"10.1016\/j.mehy.2013.09.030_b0070","first-page":"5830","article-title":"Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases","volume":"59","author":"Zhong","year":"1999","journal-title":"Cancer Res"},{"key":"10.1016\/j.mehy.2013.09.030_b0075","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1023\/A:1026544214667","article-title":"HIF-1: using two hands to flip the angiogenic switch","volume":"19","author":"Semenza","year":"2000","journal-title":"Cancer Metastasis Rev"},{"key":"10.1016\/j.mehy.2013.09.030_b0080","first-page":"2595","article-title":"Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival","volume":"8","author":"Hui","year":"2002","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.mehy.2013.09.030_b0085","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1038\/sj.onc.1203483","article-title":"STAT signaling in head and neck cancer","volume":"19","author":"Song","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.mehy.2013.09.030_b0090","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1182\/blood.V93.8.2627","article-title":"Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo","volume":"93","author":"Ribatti","year":"1999","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.mehy.2013.09.030_b0095","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1158\/1078-0432.20.11.1","article-title":"Erythropoietin and erythropoietin receptor expression in head and neck cancer: relationship to tumor hypoxia","volume":"11","author":"Arcasoy","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.mehy.2013.09.030_b0100","first-page":"7066","article-title":"Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer","volume":"62","author":"Kaanders","year":"2002","journal-title":"Cancer Res"},{"key":"10.1016\/j.mehy.2013.09.030_b0105","doi-asserted-by":"crossref","first-page":"3974","DOI":"10.1073\/pnas.91.9.3974","article-title":"Erythropoietin receptor mRNA expression in human endothelial cells","volume":"91","author":"Anagnostou","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.mehy.2013.09.030_b0110","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1182\/blood.V93.8.2627","article-title":"Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo","volume":"93","author":"Ribatti","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.mehy.2013.09.030_b0115","doi-asserted-by":"crossref","first-page":"25381","DOI":"10.1074\/jbc.273.39.25381","article-title":"Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis","volume":"273","author":"Yasuda","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mehy.2013.09.030_b0120","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/S0002-9440(10)63459-1","article-title":"A novel role for erythropoietin during fibrin-induced wound-healing response","volume":"163","author":"Haroon","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.mehy.2013.09.030_b0125","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0006-291X(03)01303-2","article-title":"Expression of erythropoietin receptor splice variants in human cancer","volume":"307","author":"Arcasoy","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"issue":"9392","key":"10.1016\/j.mehy.2013.09.030_b0130","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/S0140-6736(03)14567-9","article-title":"Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial","volume":"362","author":"Henke","year":"2003","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.mehy.2013.09.030_b0135","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD006158.pub2","article-title":"Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer","author":"Lambin","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"issue":"34","key":"10.1016\/j.mehy.2013.09.030_b0140","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.2009.22.3693","article-title":"Effect of epoetin alfa on survival and cancer treatment-related anemia and fatigue in patients receiving radical radiotherapy with curative intent for head and neck cancer","volume":"27","author":"Hoskin","year":"2009","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1016\/j.mehy.2013.09.030_b0145","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.ijrobp.2007.04.063","article-title":"Radiotherapy with or without erythropoietin for anemic patients with head and neck cancer: a randomized trial of the Radiation Therapy Oncology Group (RTOG 99\u201303)","volume":"69","author":"Machtay","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"29","key":"10.1016\/j.mehy.2013.09.030_b0150","doi-asserted-by":"crossref","first-page":"4708","DOI":"10.1200\/JCO.2006.06.2737","article-title":"Do erythropoietin receptors on cancer cells explain unexpected clinical findings?","volume":"24","author":"Henke","year":"2006","journal-title":"J Clin Oncol"},{"issue":"27","key":"10.1016\/j.mehy.2013.09.030_b0155","first-page":"4442","volume":"24","author":"Lai","year":"2005","journal-title":"Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma."},{"issue":"5","key":"10.1016\/j.mehy.2013.09.030_b0160","first-page":"1689","article-title":"Multicenter randomized phase II study of paclitaxel (1-hour infusion), fluorouracil, hydroxyurea, and concomitant twice daily radiation with or without erythropoietin for advanced head and neck cancer","volume":"9","author":"Rosen","year":"2003","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.mehy.2013.09.030_b0165","series-title":"American Joint Committee on Cancer. AJCC Cancer Staging Manual","author":"Edge","year":"2010"},{"key":"10.1016\/j.mehy.2013.09.030_b0170","unstructured":"Ridge JA, Mehra R, Lango MN, Feigenberg S. (8.3.2013) Head and neck tumors; cancer management: online edition http:\/\/www.cancernetwork.com\/cancer-management\/head-and-neck\/article\/10165\/1802498?pageNumber=7 (3.4.2013.)."}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987713004684?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987713004684?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T00:01:19Z","timestamp":1688515279000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987713004684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0306987713004684"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2013.09.030","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of erythropoietin and erythropoietin receptor in malignant laryngeal tumors","name":"articletitle","label":"Article Title"},{"value":"Medical Hypotheses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mehy.2013.09.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}