{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T19:51:22Z","timestamp":1770753082949,"version":"3.50.0"},"reference-count":119,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81200797"],"award-info":[{"award-number":["81200797"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81371147"],"award-info":[{"award-number":["81371147"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81170972"],"award-info":[{"award-number":["81170972"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.mehy.2014.05.011","type":"journal-article","created":{"date-parts":[[2014,5,24]],"date-time":"2014-05-24T04:18:38Z","timestamp":1400905118000},"page":"131-136","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["HBO: A possible supplementary therapy for oral potentially malignant disorders"],"prefix":"10.1016","volume":"83","author":[{"given":"Xiaojing","family":"Ye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.mehy.2014.05.011_b0005","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1600-0714.2007.00582.x","article-title":"Nomenclature and classification of potentially malignant disorders of the oral mucosa","volume":"36","author":"Warnakulasuriya","year":"2007","journal-title":"J Oral Pathol Med"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0010","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/0030-4220(78)90383-3","article-title":"Definition of leukoplakia and related lesions: an aid to studies on oral precancer","volume":"46","author":"Kramer","year":"1978","journal-title":"Oral Surg Oral Med Oral Pathol"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0015","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1054\/ijom.2002.0220","article-title":"Field change and oral cancer: new evidence for widespread carcinogenesis?","volume":"31","author":"Thomson","year":"2002","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"9","key":"10.1016\/j.mehy.2014.05.011_b0020","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.oraloncology.2012.02.025","article-title":"Oral potentially malignant disorders: precising the definition","volume":"48","author":"Sarode","year":"2012","journal-title":"Oral Oncol"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0025","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.oraloncology.2010.02.016","article-title":"Potentially malignant disorders of the oral and oropharyngeal mucosa; present concepts of management","volume":"46","author":"van der Waal","year":"2010","journal-title":"Oral Oncol"},{"issue":"8","key":"10.1016\/j.mehy.2014.05.011_b0030","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/S1368-8375(03)00102-7","article-title":"Pooled estimate of world leukoplakia prevalence: a systematic review","volume":"39","author":"Petti","year":"2003","journal-title":"Oral Oncol"},{"issue":"8","key":"10.1016\/j.mehy.2014.05.011_b0035","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1600-0714.2008.00662.x","article-title":"The reported prevalence of oral lichen planus: a review and critique","volume":"37","author":"McCartan","year":"2008","journal-title":"J Oral Pathol Med"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0040","first-page":"783","article-title":"Prevalence of oral submucous fibrosis in the high natural radiation belt of Kerala, south India","volume":"70","author":"Rajendran","year":"1992","journal-title":"Bull World Health Organ"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0045","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1177\/154411130301400105","article-title":"Prognosis of oral pre-malignant lesions: significance of clinical, histopathological, and molecular biological characteristics","volume":"14","author":"Reibel","year":"2003","journal-title":"Crit Rev Oral Biol Med"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0050","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2334\/josnusd.49.89","article-title":"Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation","volume":"49","author":"Ismail","year":"2007","journal-title":"J Oral Sci"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0055","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/j.1600-0528.1985.tb00468.x","article-title":"Malignant transformation rate in oral submucous fibrosis over a 17-year period","volume":"13","author":"Murti","year":"1985","journal-title":"Commun Dent Oral Epidemiol"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0060","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1600-0714.2005.00325.x","article-title":"Molecular pathogenesis of oral submucous fibrosis\u2013a collagen metabolic disorder","volume":"34","author":"Rajalalitha","year":"2005","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.mehy.2014.05.011_b0065","article-title":"Phototherapy approaches in treatment of oral lichen planus","author":"Pavlic","year":"2013","journal-title":"Photodermatol Photoimmunol Photomed"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0070","first-page":"366","article-title":"A study of millimeter wave\u2019s clinical and immunological effects on oral lichen planus patients","volume":"19","author":"Jin","year":"2001","journal-title":"Hua Xi Kou Qiang Yi Xue Za Zhi"},{"issue":"34","key":"10.1016\/j.mehy.2014.05.011_b0075","doi-asserted-by":"crossref","first-page":"5470","DOI":"10.2174\/138161212803307617","article-title":"Topical therapies for oral lichen planus management and their efficacy: a narrative review","volume":"18","author":"Bagan","year":"2012","journal-title":"Curr Pharm Des"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0080","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4103\/0973-029X.84474","article-title":"Oral lichen planus: An update on pathogenesis and treatment","volume":"15","author":"Lavanya","year":"2011","journal-title":"J Oral Maxillofac Pathol JOMFP"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0085","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.drup.2011.03.001","article-title":"Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways","volume":"14","author":"Rohwer","year":"2011","journal-title":"Drug Resist Updates"},{"issue":"7","key":"10.1016\/j.mehy.2014.05.011_b0090","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/qjmed\/hch074","article-title":"Hyperbaric oxygen: its uses, mechanisms of action and outcomes","volume":"97","author":"Gill","year":"2004","journal-title":"QJM Monthly J Assoc Physicians"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0095","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/dth.12053","article-title":"Hyperbaric oxygen for chronic wounds","volume":"26","author":"Goldstein","year":"2013","journal-title":"Dermatol Ther"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0100","first-page":"71","article-title":"Treatment of carbon monoxide poisoning with hyperbaric oxygen and therapeutic hypothermia","volume":"40","author":"Feldman","year":"2013","journal-title":"Undersea Hyperb Med"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0105","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/s10147-013-0537-6","article-title":"Old but new methods in radiation oncology: hyperbaric oxygen therapy","volume":"18","author":"Ogawa","year":"2013","journal-title":"Int J Clin Oncol"},{"issue":"7","key":"10.1016\/j.mehy.2014.05.011_b0110","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1007\/s00134-012-2558-4","article-title":"Hyperbaric oxygen therapy in necrotising soft tissue infections: a study of patients in the United States Nationwide Inpatient Sample","volume":"38","author":"Soh","year":"2012","journal-title":"Intensive Care Med"},{"issue":"5","key":"10.1016\/j.mehy.2014.05.011_b0115","first-page":"321","article-title":"Treatment of acute stroke with hyperbaric oxygen: time window for efficacy","volume":"38","author":"McCormick","year":"2011","journal-title":"Undersea Hyperb Med"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0120","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1067\/mtc.2003.90","article-title":"Hyperbaric oxygen as a chemotherapy adjuvant in the treatment of metastatic lung tumors in a rat model","volume":"125","author":"Petre","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0125","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1158\/0008-5472.CAN-05-3143","article-title":"Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation","volume":"66","author":"Awale","year":"2006","journal-title":"Cancer Res"},{"key":"10.1016\/j.mehy.2014.05.011_b0130","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/978-1-4020-5133-3_16","article-title":"Effect of hypoxia on the tumor phenotype: the neuroblastoma and breast cancer models","volume":"587","author":"Holmquist","year":"2006","journal-title":"Adv Exp Med Biol"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0135","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/nrc704","article-title":"Hypoxia \u2013 a key regulatory factor in tumour growth","volume":"2","author":"Harris","year":"2002","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.22462\/01.03.2021.1","article-title":"Hyperbaric oxygen: does it promote growth or recurrence of malignancy?","volume":"30","author":"Feldmeier","year":"2003","journal-title":"Undersea Hyperb Med"},{"issue":"12","key":"10.1016\/j.mehy.2014.05.011_b0145","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1007\/s00268-006-0190-6","article-title":"Hyperbaric oxygen therapy for malignancy: a review","volume":"30","author":"Daruwalla","year":"2006","journal-title":"World J Surg"},{"issue":"5","key":"10.1016\/j.mehy.2014.05.011_b0150","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/hed.20169","article-title":"Effects of hyperbaric oxygen exposure on experimental head and neck tumor growth, oxygenation, and vasculature","volume":"27","author":"Shi","year":"2005","journal-title":"Head Neck"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0155","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.bjoms.2009.10.036","article-title":"Hyperbaric oxygen in the management of late radiation injury to the head and neck. Part I: treatment","volume":"49","author":"Shaw","year":"2011","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0160","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.ijrobp.2008.11.056","article-title":"Early hyperbaric oxygen therapy for reducing radiotherapy side effects: early results of a randomized trial in oropharyngeal and nasopharyngeal cancer","volume":"75","author":"Teguh","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0165","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.ijom.2007.11.013","article-title":"The effect of hyperbaric oxygen therapy on quality of life in oral and oropharyngeal cancer patients treated with radiotherapy","volume":"37","author":"Gerlach","year":"2008","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"8","key":"10.1016\/j.mehy.2014.05.011_b0170","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1097\/00005537-199608000-00008","article-title":"Effect of hyperbaric oxygenation on existing oral mucosal carcinoma","volume":"106","author":"McDonald","year":"1996","journal-title":"Laryngoscope"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0175","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S1808-8694(15)31102-2","article-title":"Oral lichen planus: clinical and histopathological considerations","volume":"74","author":"Sousa","year":"2008","journal-title":"Braz J Otorhinolaryngol"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0180","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1046\/j.1365-2230.2000.00607.x","article-title":"The management of oral lichen planus","volume":"25","author":"Setterfield","year":"2000","journal-title":"Clin Exp Dermatol"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0185","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.1016\/j.tripleo.2006.10.022","article-title":"Study of microcirculation in oral lichen planus by video-capillaroscopy","volume":"103","author":"Scardina","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0190","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1007\/s00784-011-0604-1","article-title":"Arecoline induced cell cycle arrest, apoptosis, and cytotoxicity to human endothelial cells","volume":"16","author":"Tseng","year":"2012","journal-title":"Clin Oral Investig"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0195","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/2045-9912-2-6","article-title":"Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis","volume":"2","author":"Rossignol","year":"2012","journal-title":"Med Gas Res"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0200","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s11523-012-0233-x","article-title":"Hyperbaric oxygen therapy and cancer \u2013 a review","volume":"7","author":"Moen","year":"2012","journal-title":"Targeted Oncol"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0205","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/0006-291X(91)91901-N","article-title":"Effect of hyperbaric oxygenation on macrophage function in mice","volume":"179","author":"Inamoto","year":"1991","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0210","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1046\/j.1365-2249.2003.02248.x","article-title":"Hyperbaric oxygen inhibits stimulus-induced proinflammatory cytokine synthesis by human blood-derived monocyte-macrophages","volume":"134","author":"Benson","year":"2003","journal-title":"Clin Exp Immunol"},{"issue":"9","key":"10.1016\/j.mehy.2014.05.011_b0215","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1097\/00003246-199009000-00014","article-title":"Effect of hyperbaric oxygen on murine neutrophil and T-lymphocyte functions","volume":"18","author":"Gadd","year":"1990","journal-title":"Crit Care Med"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0220","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.coi.2011.08.004","article-title":"CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes","volume":"23","author":"Haskins","year":"2011","journal-title":"Curr Opin Immunol"},{"issue":"7","key":"10.1016\/j.mehy.2014.05.011_b0225","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.2337\/db11-0516","article-title":"Prevention of autoimmune diabetes and induction of beta-cell proliferation in NOD mice by hyperbaric oxygen therapy","volume":"61","author":"Faleo","year":"2012","journal-title":"Diabetes"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0230","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0165-2478(97)00104-1","article-title":"Differential sensitivities to hyperbaric oxygen of lymphocyte subpopulations of normal and autoimmune mice","volume":"59","author":"Xu","year":"1997","journal-title":"Immunol Lett"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0235","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1177\/154411130201300405","article-title":"The pathogenesis of oral lichen planus","volume":"13","author":"Sugerman","year":"2002","journal-title":"Crit Rev Oral Biol Med"},{"issue":"7","key":"10.1016\/j.mehy.2014.05.011_b0240","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1600-0714.2011.01029.x","article-title":"Biologics, an alternative therapeutic approach for oral lichen planus","volume":"40","author":"Zhang","year":"2011","journal-title":"J Oral Pathol Med"},{"issue":"11","key":"10.1016\/j.mehy.2014.05.011_b0245","first-page":"647","article-title":"28 reports about HBO treat oral lichen planus","volume":"9","author":"Hong Duan","year":"1998","journal-title":"Med J Chin People\u2019s Armed Police Forces"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0250","first-page":"142","article-title":"The primary research about HBO treat erosive lichen planus","volume":"10","author":"Ran","year":"1994","journal-title":"J Pract Stomatol"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0255","first-page":"192","article-title":"Therapeutic effectiveness of HBO treatment on erosive oral lichen planus","volume":"5","author":"SuHua Qu","year":"1998","journal-title":"Chin J Naut Med"},{"issue":"5","key":"10.1016\/j.mehy.2014.05.011_b0260","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1152\/jappl.1994.77.5.2355","article-title":"Effect of hyperbaric oxygen on tissue distribution of mononuclear cell subsets in the rat","volume":"77","author":"Bitterman","year":"1994","journal-title":"J Appl Physiol"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0265","first-page":"216","article-title":"Exposure to increased pressure or hyperbaric oxygen suppresses interferon-gamma secretion in whole blood cultures of healthy humans","volume":"29","author":"Granowitz","year":"2002","journal-title":"Undersea Hyperb Med"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0270","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1177\/108155890305100424","article-title":"Effects of hyperbaric oxygen on proliferative and apoptotic activities and reactive oxygen species generation in mouse fibroblast 3T3\/J2 cell line","volume":"51","author":"Conconi","year":"2003","journal-title":"J Investig Med"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0275","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1524-475X.2008.00398.x","article-title":"Hyperbaric oxygen attenuates cell growth in skin fibroblasts cultured in a high-glucose medium","volume":"16","author":"Lin","year":"2008","journal-title":"Wound Repair Regen"},{"issue":"7","key":"10.1016\/j.mehy.2014.05.011_b0280","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.bjoms.2012.08.014","article-title":"Oral submucous fibrosis: an overview of the aetiology, pathogenesis, classification, and principles of management","volume":"51","author":"Arakeri","year":"2013","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"Suppl 1","key":"10.1016\/j.mehy.2014.05.011_b0285","doi-asserted-by":"crossref","first-page":"S85","DOI":"10.4103\/0975-7406.113303","article-title":"Pathogenesis and therapeutic intervention of oral submucous fibrosis","volume":"5","author":"Yoithapprabhunath","year":"2013","journal-title":"J Pharm Bioallied Sci"},{"issue":"5","key":"10.1016\/j.mehy.2014.05.011_b0290","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1600-0714.2009.00758.x","article-title":"Arecoline and oral keratinocytes may affect the collagen metabolism of fibroblasts","volume":"38","author":"Xia","year":"2009","journal-title":"J Oral Pathol Med"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0295","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1600-0714.1999.tb01997.x","article-title":"Deficiency in collagen and fibronectin phagocytosis by human buccal mucosa fibroblasts in vitro as a possible mechanism for oral submucous fibrosis","volume":"28","author":"Tsai","year":"1999","journal-title":"J Oral Pathol Med"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0300","doi-asserted-by":"crossref","first-page":"199","DOI":"10.4103\/0973-1482.98970","article-title":"Pathogenesis of oral submucous fibrosis","volume":"8","author":"Khan","year":"2012","journal-title":"J Cancer Res Ther"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0305","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0003-9969(87)90138-5","article-title":"An in-vitro comparison of human fibroblasts from normal and oral submucous fibrosis tissue","volume":"32","author":"Meghji","year":"1987","journal-title":"Arch Oral Biol"},{"issue":"22","key":"10.1016\/j.mehy.2014.05.011_b0310","doi-asserted-by":"crossref","first-page":"19575","DOI":"10.1074\/jbc.R200030200","article-title":"Hypoxia-inducible factor and its biomedical relevance","volume":"278","author":"Huang","year":"2003","journal-title":"J Biol Chem"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0315","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.tips.2012.01.005","article-title":"Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy","volume":"33","author":"Semenza","year":"2012","journal-title":"Trends Pharmacol Sci"},{"issue":"5","key":"10.1016\/j.mehy.2014.05.011_b0320","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/onc.2009.441","article-title":"Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics","volume":"29","author":"Semenza","year":"2010","journal-title":"Oncogene"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0325","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1677\/erc.1.00728","article-title":"Hypoxia-inducible factor-1 in human breast and prostate cancer","volume":"13","author":"Kimbro","year":"2006","journal-title":"Endocr Relat Cancer"},{"issue":"34","key":"10.1016\/j.mehy.2014.05.011_b0330","doi-asserted-by":"crossref","first-page":"24171","DOI":"10.1074\/jbc.M604507200","article-title":"Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression","volume":"281","author":"McMahon","year":"2006","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0335","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1365-2559.2005.02045.x","article-title":"Hypoxia-inducible factor-1alpha is associated with angiogenesis, and expression of bFGF, PDGF-BB, and EGFR in invasive breast cancer","volume":"46","author":"Bos","year":"2005","journal-title":"Histopathology"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0340","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/pros.10279","article-title":"Increased growth factor production in a human prostatic stromal cell culture model caused by hypoxia","volume":"57","author":"Berger","year":"2003","journal-title":"Prostate"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0345","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3109\/08977190109001073","article-title":"Role of AP-1 and HIF-1 transcription factors in TGF-beta activation of VEGF expression","volume":"19","author":"Shih","year":"2001","journal-title":"Growth Factors"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0350","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1002\/jso.20443","article-title":"Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas","volume":"94","author":"Giatromanolaki","year":"2006","journal-title":"J Surg Oncol"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0355","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/ijc.11068","article-title":"Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma","volume":"105","author":"Kuwai","year":"2003","journal-title":"Int J Cancer"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0360","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1046\/j.1523-1755.2000.00419.x","article-title":"Hypoxia promotes fibrogenesis in human renal fibroblasts","volume":"58","author":"Norman","year":"2000","journal-title":"Kidney Int"},{"issue":"1\u20132","key":"10.1016\/j.mehy.2014.05.011_b0365","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1043-4666(03)00253-9","article-title":"Hypoxia modulates the effects of transforming growth factor-beta isoforms on matrix-formation by primary human lung fibroblasts","volume":"24","author":"Papakonstantinou","year":"2003","journal-title":"Cytokine"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0370","doi-asserted-by":"crossref","first-page":"R193","DOI":"10.1186\/ar756","article-title":"Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis","volume":"5","author":"Giatromanolaki","year":"2003","journal-title":"Arthritis Res Ther"},{"issue":"9","key":"10.1016\/j.mehy.2014.05.011_b0375","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1248\/bpb.34.1432","article-title":"Emodin inhibits proinflammatory responses and inactivates histone deacetylase 1 in hypoxic rheumatoid synoviocytes","volume":"34","author":"Ha","year":"2011","journal-title":"Biol Pharm Bull"},{"issue":"17","key":"10.1016\/j.mehy.2014.05.011_b0380","doi-asserted-by":"crossref","first-page":"171803","DOI":"10.1103\/PhysRevLett.100.171803","article-title":"Observation of tree-level B decays with ss production from gluon radiation","volume":"100","author":"Aubert","year":"2008","journal-title":"Phys Rev Lett"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0385","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1601-0825.2009.01645.x","article-title":"Altered expression of mRNA for HIF-1alpha and its target genes RTP801 and VEGF in patients with oral lichen planus","volume":"16","author":"Ding","year":"2010","journal-title":"Oral Dis"},{"key":"10.1016\/j.mehy.2014.05.011_b0390","first-page":"21","article-title":"High HIF-1alpha expression genotypes in oral lichen planus","author":"de Carvalho Fraga","year":"2013","journal-title":"Clin Oral Investig"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0395","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/j.1600-0714.2007.00625.x","article-title":"Upregulation of HIF-1alpha in malignant transformation of oral submucous fibrosis","volume":"37","author":"Tilakaratne","year":"2008","journal-title":"J Oral Pathol Med"},{"issue":"5","key":"10.1016\/j.mehy.2014.05.011_b0400","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0002-9610(05)81019-0","article-title":"Relationship of oxygen dose to angiogenesis induction in irradiated tissue","volume":"160","author":"Marx","year":"1990","journal-title":"Am J Surg"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0405","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s11373-005-9037-7","article-title":"Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun\/AP-1 activation in human umbilical vein endothelial cells","volume":"13","author":"Lee","year":"2006","journal-title":"J Biomed Sci"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0410","doi-asserted-by":"crossref","first-page":"C1358","DOI":"10.1152\/ajpcell.2001.280.6.C1358","article-title":"Role of vascular endothelial growth factor in regulation of physiological angiogenesis","volume":"280","author":"Ferrara","year":"2001","journal-title":"Am J Physiol Cell Physiol"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0415","doi-asserted-by":"crossref","first-page":"45","DOI":"10.4103\/0973-029X.92972","article-title":"Role of angiogenesis in the pathogenesis of oral lichen planus","volume":"16","author":"Mittal","year":"2012","journal-title":"J Oral Maxillofac Pathol JOMFP"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0420","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s00005-011-0150-1","article-title":"Angiogenesis in oral lichen planus: an in vivo and immunohistological evaluation","volume":"59","author":"Scardina","year":"2011","journal-title":"Arch Immunol Ther Ex"},{"issue":"5","key":"10.1016\/j.mehy.2014.05.011_b0425","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.tripleo.2006.05.023","article-title":"Assessment of local angiogenesis and vascular endothelial growth factor in the patients with atrophic-erosive and reticular oral lichen planus","volume":"103","author":"Tao","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0430","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.tripleo.2010.11.018","article-title":"Increased subepithelial vascularization and VEGF expression reveal potentially malignant changes in human oral mucosa lesions","volume":"111","author":"Gandolfo","year":"2011","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"12","key":"10.1016\/j.mehy.2014.05.011_b0435","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1016\/j.ijom.2011.12.038","article-title":"VEGF expression from human dysplastic or malignant oral epithelium may be related to mast cell density and the subsequent angiogenetic phenomena","volume":"41","author":"Michailidou","year":"2012","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0440","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.oraloncology.2005.06.020","article-title":"The role of vascular endothelial growth factor (VEGF) in oral dysplasia and oral squamous cell carcinoma","volume":"42","author":"Johnstone","year":"2006","journal-title":"Oral Oncol"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0445","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1177\/147323001204000318","article-title":"The synergistic therapeutic effect of temozolomide and hyperbaric oxygen on glioma U251 cell lines is accompanied by alterations in vascular endothelial growth factor and multidrug resistance-associated protein-1 levels","volume":"40","author":"Lu","year":"2012","journal-title":"J Int Med Res"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0450","first-page":"55","article-title":"A morphometric study on the microvessel in oral submucous fibrosis","volume":"25","author":"Fang","year":"2000","journal-title":"Hunan Yi Ke Da Xue Xue Bao"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0455","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1524-475X.2008.00372.x","article-title":"The use of hyperbaric oxygen therapy to treat chronic wounds: A review","volume":"16","author":"Thackham","year":"2008","journal-title":"Wound Repair Regen"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0460","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/j.1524-475X.2005.00078.x","article-title":"Hyperoxia and angiogenesis","volume":"13","author":"Hopf","year":"2005","journal-title":"Wound Repair Regen"},{"issue":"7","key":"10.1016\/j.mehy.2014.05.011_b0465","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s11626-011-9418-3","article-title":"Keloid skin scars: the influence of hyperbaric oxygenation on fibroblast growth and on the expression of messenger RNA for insulin like growth factor and for transforming growth factor","volume":"47","author":"Romero-Valdovinos","year":"2011","journal-title":"In Vitro Cell Dev Biol Anim"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0470","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.clim.2004.12.003","article-title":"A comparison of the pro-inflammatory, NF-kappaB-dependent cytokines: TNF-alpha, IL-1-alpha, IL-6, and IL-8 in different oral fluids from oral lichen planus patients","volume":"114","author":"Rhodus","year":"2005","journal-title":"Clin Immunol"},{"key":"10.1016\/j.mehy.2014.05.011_b0475","doi-asserted-by":"crossref","first-page":"847632","DOI":"10.1155\/2010\/847632","article-title":"Levels of salivary IFN-gamma, TNF-alfa, and TNF receptor-2 as prognostic markers in (erosive) oral lichen planus","volume":"2010","author":"Ghallab","year":"2010","journal-title":"Mediators Inflammation"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0480","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.cyto.2013.01.020","article-title":"Increasing CCL5\/CCR5 on CD4+ T cells in peripheral blood of oral lichen planus","volume":"62","author":"Hu","year":"2013","journal-title":"Cytokine"},{"issue":"8","key":"10.1016\/j.mehy.2014.05.011_b0485","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1600-0714.2010.00902.x","article-title":"Increased expression of Smad proteins, and in particular Smad3, in oral lichen planus compared to normal oral mucosa","volume":"39","author":"Danielsson","year":"2010","journal-title":"J Oral Pathol Med"},{"issue":"9","key":"10.1016\/j.mehy.2014.05.011_b0490","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1002\/hed.20869","article-title":"MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus","volume":"30","author":"Chen","year":"2008","journal-title":"Head Neck"},{"issue":"13","key":"10.1016\/j.mehy.2014.05.011_b0495","doi-asserted-by":"crossref","first-page":"4405","DOI":"10.1158\/0008-5472.CAN-04-1032","article-title":"Overexpression of transforming growth factor beta1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation","volume":"64","author":"Lu","year":"2004","journal-title":"Cancer Res"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0500","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1034\/j.1600-0714.2003.00077.x","article-title":"Th1 cytokines in oral lichen planus","volume":"32","author":"Khan","year":"2003","journal-title":"J Oral Pathol Med"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0505","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.tripleo.2009.08.013","article-title":"Gene expression of oncogenes, antimicrobial peptides, and cytokines in the development of oral leukoplakia","volume":"110","author":"Wenghoefer","year":"2010","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.mehy.2014.05.011_b0510","article-title":"Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin-6, TNF-alpha and EGF production in chronic leg wound healing","author":"Nasole","year":"2013","journal-title":"J Enzyme Inhib Med Chem"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0515","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1023\/A:1027378532003","article-title":"Modification of in vivo and in vitro TNF-alpha, IL-1, and IL-6 secretion by circulating monocytes during hyperbaric oxygen treatment in patients with perianal Crohn\u2019s disease","volume":"17","author":"Weisz","year":"1997","journal-title":"J Clin Immunol"},{"issue":"12","key":"10.1016\/j.mehy.2014.05.011_b0520","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1097\/00003246-199812000-00022","article-title":"Effects of hyperbaric oxygen exposure on a zymosan-induced shock model","volume":"26","author":"Luongo","year":"1998","journal-title":"Crit Care Med"},{"issue":"5","key":"10.1016\/j.mehy.2014.05.011_b0525","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.4049\/jimmunol.128.5.2177","article-title":"Interleukin 1, a potential regulator of fibroblast proliferation","volume":"128","author":"Schmidt","year":"1982","journal-title":"J Immunol"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0530","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1084\/jem.163.3.632","article-title":"Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors","volume":"163","author":"Vilcek","year":"1986","journal-title":"J Exp Med"},{"issue":"11","key":"10.1016\/j.mehy.2014.05.011_b0535","doi-asserted-by":"crossref","first-page":"4354","DOI":"10.4049\/jimmunol.156.11.4354","article-title":"TNF-alpha inactivation of collagen receptors: implications for fibroblast function and fibrosis","volume":"156","author":"Chou","year":"1996","journal-title":"J Immunol"},{"issue":"9","key":"10.1016\/j.mehy.2014.05.011_b0540","doi-asserted-by":"crossref","first-page":"4188","DOI":"10.4049\/jimmunol.150.9.4188","article-title":"Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure","volume":"150","author":"Zhang","year":"1993","journal-title":"J Immunol"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0545","first-page":"217","article-title":"Whole blood pro-inflammatory cytokines and adhesion molecules post-lipopolysaccharides exposure in hyperbaric conditions","volume":"15","author":"Fildissis","year":"2004","journal-title":"Eur Cytokine Netw"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0550","doi-asserted-by":"crossref","first-page":"C292","DOI":"10.1152\/ajpcell.2000.278.2.C292","article-title":"Hyperbaric oxygen downregulates ICAM-1 expression induced by hypoxia and hypoglycemia: the role of NOS","volume":"278","author":"Buras","year":"2000","journal-title":"Am J Physiol Cell Physiol"},{"issue":"4","key":"10.1016\/j.mehy.2014.05.011_b0555","first-page":"151","article-title":"Recent advances on the pathogenesis of oral lichen planus (OLP). The adhesion molecules","volume":"48","author":"Femiano","year":"1999","journal-title":"Minerva Stomatol"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0560","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1600-0714.1994.tb00056.x","article-title":"VCAM-1 and ICAM-1 are expressed by Langerhans cells, macrophages and endothelial cells in oral lichen planus","volume":"23","author":"Walton","year":"1994","journal-title":"J Oral Pathol Med"},{"issue":"2","key":"10.1016\/j.mehy.2014.05.011_b0565","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1600-0714.1992.tb00981.x","article-title":"Expression of the CD54 (ICAM-1) and CD11a (LFA-1) adhesion molecules in oral mucosal inflammation","volume":"21","author":"Verdickt","year":"1992","journal-title":"J Oral Pathol Med"},{"issue":"10","key":"10.1016\/j.mehy.2014.05.011_b0570","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1600-0714.1990.tb00787.x","article-title":"Induction and upregulation of adhesion receptors in oral and dermal lichen planus","volume":"19","author":"Konter","year":"1990","journal-title":"J Oral Pathol Med"},{"issue":"3","key":"10.1016\/j.mehy.2014.05.011_b0575","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1600-0714.1996.tb00204.x","article-title":"Heterogeneity of ICAM-1 expression, and cytokine regulation of ICAM-1 expression, in skin and oral keratinocytes","volume":"25","author":"Li","year":"1996","journal-title":"J Oral Pathol Med"},{"issue":"8","key":"10.1016\/j.mehy.2014.05.011_b0580","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/00000446-200108000-00015","article-title":"Hyperbaric oxygen therapy","volume":"101","author":"Leifer","year":"2001","journal-title":"Am J Nurs"},{"issue":"1","key":"10.1016\/j.mehy.2014.05.011_b0585","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0094-1298(02)00068-8","article-title":"Hyperbaric oxygen and wound healing","volume":"30","author":"Zamboni","year":"2003","journal-title":"Clin Plast Surg"},{"issue":"6","key":"10.1016\/j.mehy.2014.05.011_b0590","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4037\/ccn2002.22.6.52","article-title":"Using hyperbaric oxygen to treat diabetic foot ulcers: safety and effectiveness","volume":"22","author":"Heyneman","year":"2002","journal-title":"Crit Care Nurse"},{"issue":"7166","key":"10.1016\/j.mehy.2014.05.011_b0595","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1136\/bmj.317.7166.1140","article-title":"Hyperbaric oxygen therapy","volume":"317","author":"Leach","year":"1998","journal-title":"BMJ"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987714002151?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987714002151?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:13:55Z","timestamp":1759691635000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987714002151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":119,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S0306987714002151"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2014.05.011","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HBO: A possible supplementary therapy for oral potentially malignant disorders","name":"articletitle","label":"Article Title"},{"value":"Medical Hypotheses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mehy.2014.05.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}