{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T05:10:10Z","timestamp":1690780210866},"reference-count":57,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["medical-hypotheses.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.mehy.2014.12.011","type":"journal-article","created":{"date-parts":[[2014,12,26]],"date-time":"2014-12-26T16:44:16Z","timestamp":1419612256000},"page":"94-99","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fundamental immunological problems associated with \u201ctransmissible spongiform encephalopathies\u201d"],"prefix":"10.1016","volume":"84","author":[{"given":"Alan","family":"Ebringer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taha","family":"Rashid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clyde","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2014.12.011_b0005","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1136\/vr.121.18.419","article-title":"A novel progressive spongiform encephalopathy in cattle","volume":"121","author":"Wells","year":"1987","journal-title":"Vet Rec"},{"key":"10.1016\/j.mehy.2014.12.011_b0010","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1089\/jir.2011.0072","article-title":"The immune pathogenesis of experimental autoimmune encephalopathies: lesson learned for multiple sclerosis?","volume":"31","author":"Kuerten","year":"2011","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.mehy.2014.12.011_b0015","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF00313635","article-title":"Past infectious events and disease evolution in multiple sclerosis","volume":"230","author":"Lamoureux","year":"1983","journal-title":"J Neurol"},{"key":"10.1016\/j.mehy.2014.12.011_b0020","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S1474-4422(13)70038-3","article-title":"Human rabies: neuropathogenesis, diagnosis, and management","volume":"12","author":"Hemachudha","year":"2013","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.mehy.2014.12.011_b0025","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1136\/jnnp.73.1.82","article-title":"Louis Pasteur and rabies; a brief note","volume":"73","author":"Pearce","year":"2002","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.mehy.2014.12.011_b0030","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1365-2249.2012.04592.x","article-title":"Developments in rabies vaccines","volume":"169","author":"Hicks","year":"2012","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.mehy.2014.12.011_b0035","first-page":"964","article-title":"La paralysie ascendante mortelle survenue apr\u00e8s le traitement antirabique","volume":"64","author":"Babes","year":"1908","journal-title":"C R Soc Biol"},{"key":"10.1016\/j.mehy.2014.12.011_b0040","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1017\/S0022172400017800","article-title":"The effects of the injection of normal brain emulsion into rabbits with special reference to the aetiology of the paralytic accidents of antirabic treatment","volume":"32","author":"Hurst","year":"1932","journal-title":"J Hyg (Lond)"},{"key":"10.1016\/j.mehy.2014.12.011_b0045","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1084\/jem.58.1.39","article-title":"Observations on attempts to produce acute disseminated encephalomyelitis in monkeys","volume":"58","author":"Rivers","year":"1933","journal-title":"J Exp Med"},{"key":"10.1016\/j.mehy.2014.12.011_b0050","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1084\/jem.85.1.117","article-title":"The rapid production of acute disseminated encephalomyelitis in rhesus monkeys by injection of heterologous and homologous brain tissue with adjuvants","volume":"85","author":"Kabat","year":"1947","journal-title":"J Exp Med"},{"key":"10.1016\/j.mehy.2014.12.011_b0055","doi-asserted-by":"crossref","first-page":"417","DOI":"10.4049\/jimmunol.76.6.417","article-title":"Studies on organ specificity. V. Changes in the thyroid glands of rabbits following active immunization with rabbit thyroid extracts","volume":"76","author":"Rose","year":"1956","journal-title":"J Immunol"},{"key":"10.1016\/j.mehy.2014.12.011_b0290","first-page":"82","article-title":"Uber das Wesen der spezifischer Ver\u00e4nderung der Niere und der Leber durch das Nephrotoxin bzw. das Hepatoxin","volume":"91","author":"Masugi","year":"1933","journal-title":"Beitr path Anat"},{"key":"10.1016\/j.mehy.2014.12.011_b0065","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1098\/rspb.1958.0058","article-title":"The homograft reaction","volume":"149","author":"Medawar","year":"1958","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"10.1016\/j.mehy.2014.12.011_b0070","first-page":"472","article-title":"An ultrastructural study of experimental demyelination and remyelination. III. Chronic experimental allergic encephalomyelitis in the central nervous system","volume":"21","author":"Prineas","year":"1969","journal-title":"Lab Invest"},{"key":"10.1016\/j.mehy.2014.12.011_b0075","first-page":"369","article-title":"Chronic experimental allergic encephalomyelitis in inbred guinea pigs. An ultrastructural study","volume":"31","author":"Raine","year":"1974","journal-title":"Lab Invest"},{"key":"10.1016\/j.mehy.2014.12.011_b0080","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0165-5728(83)90001-2","article-title":"Immunoglobulin-deficient rats fail to develop experimental allergic encephalomyelitis","volume":"5","author":"Willenborg","year":"1983","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.mehy.2014.12.011_b0085","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0368-1742(13)80060-4","article-title":"Scrapie: an obscure disease of sheep","volume":"26","author":"Stockman","year":"1913","journal-title":"J Comp Pathol"},{"key":"10.1016\/j.mehy.2014.12.011_b0090","first-page":"1552","article-title":"La maladie dite remblante du mouton est-elle inoculable?","volume":"203","author":"Cuille","year":"1936","journal-title":"Compt Rend l\u2019Acad Sci"},{"key":"10.1016\/j.mehy.2014.12.011_b0095","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1099\/vir.0.062356-0","article-title":"Louping ill virus: an endemic tick-borne disease of Great Britain","volume":"95","author":"Jeffries","year":"2014","journal-title":"J Gen Virol"},{"key":"10.1016\/j.mehy.2014.12.011_b0100","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0368-1742(50)80024-3","article-title":"Scrapie in sheep","volume":"60","author":"Greig","year":"1950","journal-title":"J Comp Path"},{"key":"10.1016\/j.mehy.2014.12.011_b0105","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0007-1935(17)50172-4","article-title":"A chronic encephalitis of sheep","volume":"10","author":"Sigurdsson","year":"1954","journal-title":"Brit Vet J"},{"key":"10.1016\/j.mehy.2014.12.011_b0110","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/S0368-1742(59)80029-1","article-title":"Experimental production of scrapie in goats","volume":"69","author":"Pattison","year":"1959","journal-title":"J Comp Path"},{"key":"10.1016\/j.mehy.2014.12.011_b0115","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.4049\/jimmunol.111.5.1407","article-title":"Failure to demonstrate a humoral immune response to scrapie infection in mice","volume":"111","author":"Porter","year":"1973","journal-title":"J Immunol"},{"key":"10.1016\/j.mehy.2014.12.011_b0295","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1093\/infdis\/120.6.713","article-title":"A preliminary report on the experimental host range of the transmissible mink encephalopathy agent","volume":"120","author":"Marsh","year":"1969","journal-title":"J Infect Dis"},{"key":"10.1016\/j.mehy.2014.12.011_b0125","doi-asserted-by":"crossref","first-page":"89","DOI":"10.7589\/0090-3558-16.1.89","article-title":"Chronic wasting disease of captive mule deer: a spongiform encephalopathy","volume":"18","author":"Williams","year":"1980","journal-title":"J Wildl Dis"},{"key":"10.1016\/j.mehy.2014.12.011_b0300","series-title":"The BSE Inquiry","article-title":"Lord Phillips of Worth Matravers","volume":"vol. 2.","author":"Bridgeman","year":"2000"},{"key":"10.1016\/j.mehy.2014.12.011_b0135","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4161\/pri.28368","article-title":"The structure of the infectious prion protein: experimental data and molecular models","volume":"8","author":"Requena","year":"2014","journal-title":"Prion"},{"key":"10.1016\/j.mehy.2014.12.011_b0140","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1099\/0022-1317-77-7-1595","article-title":"Scrapie infection can be established readily through skin scarification in immunocompetent but not in immunodeficient mice","volume":"77","author":"Taylor","year":"1996","journal-title":"J Gen Virol"},{"key":"10.1016\/j.mehy.2014.12.011_b0145","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/0013-4694(94)90031-0","article-title":"Neurophysiological follow-up in two children with Creutzfeldt\u2013Jakob disease after human growth hormone treatment","volume":"91","author":"Richard","year":"1994","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.mehy.2014.12.011_b0150","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1136\/jnnp.55.12.1200","article-title":"A further British case of growth hormone induced Creutzfeldt\u2013Jakob disease","volume":"55","author":"Ellis","year":"1992","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.mehy.2014.12.011_b0155","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1126\/science.155.3759.212","article-title":"Transmission and passage of experimental \u201ckuru\u201d to chimpanzees","volume":"155","author":"Gajdusek","year":"1967","journal-title":"Science"},{"key":"10.1016\/j.mehy.2014.12.011_b0160","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1128\/IAI.38.1.316-324.1982","article-title":"Heterogeneic autoantibody against neurofilament protein in the sera of animals with experimental kuru, Creutzfeldt\u2013Jakob disease and natural scrapie infection","volume":"38","author":"Aoki","year":"1982","journal-title":"Infect Immun"},{"key":"10.1016\/j.mehy.2014.12.011_b0165","doi-asserted-by":"crossref","first-page":"373","DOI":"10.4161\/viru.24838","article-title":"Infectious particles, stress and induced prion amyloids: a unifying perspective","volume":"4","author":"Manuelidis","year":"2013","journal-title":"Virulence"},{"key":"10.1016\/j.mehy.2014.12.011_b0170","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/BF00409255","article-title":"Immunolgic sequelae of thermal injury autoantibodies in acute adult burn patients","volume":"273","author":"Ablin","year":"1982","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.mehy.2014.12.011_b0175","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1177\/0003319713512720","article-title":"Relationship between oxidized LDL IgM and IgG autoantibodies to ox-LDL levels with recurrent cardiovascular events in Swedish patients with previous myocardial infarction","volume":"65","author":"Crisby","year":"2013","journal-title":"Angiology"},{"key":"10.1016\/j.mehy.2014.12.011_b0180","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S0002-9343(48)90389-1","article-title":"Quantitative estimation of the albumin and gamma globulin in normal and pathologic cerebrospinal fluid by immunochemical methods","volume":"4","author":"Kabat","year":"1948","journal-title":"Am J Med"},{"key":"10.1016\/j.mehy.2014.12.011_b0185","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1093\/brain\/awl075","article-title":"Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research","volume":"129","author":"Gold","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.mehy.2014.12.011_b0190","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/0003-9861(69)90336-1","article-title":"Experimental allergic encephalomyelitis: an encephalitogenic basic protein from bovine myelin","volume":"132","author":"Eylar","year":"1969","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.mehy.2014.12.011_b0195","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1289\/ehp.971051172","article-title":"Bovine spongiform encephalopathy: is it an autoimmune disease due to bacteria showing molecular mimicry with brain antigens?","volume":"105","author":"Ebringer","year":"1997","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.mehy.2014.12.011_b0200","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1097\/00005537-200108000-00005","article-title":"Comparison of antral tap with endoscopically directed nasal culture","volume":"111","author":"Casiano","year":"2001","journal-title":"Laryngoscope"},{"key":"10.1016\/j.mehy.2014.12.011_b0205","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1128\/CDLI.8.6.1181-1188.2001","article-title":"Antibody responses to Acinetobacter species and Pseudomonas aeruginosa in multiple sclerosis: Prospects for diagnosis using the Myelin-Acinetobacter-Neurofilament antibody index","volume":"8","author":"Hughes","year":"2001","journal-title":"Clin Diag Lab Immunol"},{"key":"10.1016\/j.mehy.2014.12.011_b0210","doi-asserted-by":"crossref","first-page":"e73516","DOI":"10.1371\/journal.pone.0073516","article-title":"Dopamine receptor autoantibodies correlate with symptoms in Sydenham\u2019s chorea","volume":"8","author":"Ben-Pazi","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mehy.2014.12.011_b0215","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/ana.410210211","article-title":"A correlation between cerebrospinal fluid myelin basic protein and anti-myelin basic protein in multiple sclerosis","volume":"21","author":"Warren","year":"1987","journal-title":"Ann Neurol"},{"key":"10.1016\/j.mehy.2014.12.011_b0220","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1212\/WNL.58.9.1372","article-title":"Patients with progressive multiple sclerosis have elevated antibodies to neurofilament subunit","volume":"58","author":"Silber","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.mehy.2014.12.011_b0225","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0165-5728(03)00274-1","article-title":"Cross-reactivity between related sequences found in Acinetobacter sp., Pseudomonas aeruginosa, myelin basic protein and myelin oligodendrocyte glycoprotein in multiple sclerosis","volume":"144","author":"Hughes","year":"2003","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.mehy.2014.12.011_b0230","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1126\/science.6997994","article-title":"Autoantibodies against axonal neurofilaments in patients with kuru and Creutzfeldt\u2013Jakob disease","volume":"210","author":"Sotelo","year":"1980","journal-title":"Science"},{"key":"10.1016\/j.mehy.2014.12.011_b0305","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/362543a0","article-title":"Neurotoxicity of a prion protein fragment","volume":"362","author":"Forloni","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.mehy.2014.12.011_b0240","doi-asserted-by":"crossref","first-page":"6591","DOI":"10.1128\/IAI.67.12.6591-6595.1999","article-title":"Autoantibodies to brain components and antibodies to Acinetobacter calcoaceticus are present in bovine spongiform encephalopathy","volume":"67","author":"Tiwana","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.mehy.2014.12.011_b0245","first-page":"23","article-title":"Antibodies to Acinetobacter bacteria and bovine brain peptides, measured in bovine spongiform encephalopathy (BSE) in an attempt to develop an ante-mortem test","volume":"52","author":"Wilson","year":"2003","journal-title":"J Clin Lab Immunol"},{"key":"10.1016\/j.mehy.2014.12.011_b0310","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetimm.2003.09.009","article-title":"Antibodies to prion and Acinetobacter peptide sequences in bovine spongiform encephalopathy","volume":"98","author":"Wilson","year":"2004","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.mehy.2014.12.011_b0315","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0140-6736(86)90936-0","article-title":"Multiple sclerosis associated with sinusitis: case-controlled study in general practice","volume":"1","author":"Gay","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.mehy.2014.12.011_b0260","first-page":"118","article-title":"The incidence of sinusitis in patients with multiple sclerosis","volume":"35","author":"Jones","year":"1997","journal-title":"Rhinology"},{"key":"10.1016\/j.mehy.2014.12.011_b0265","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/BF01709360","article-title":"Sinusitis in mechanically ventilated patients and its role in the pathogenesis of nosocomial pneumonia","volume":"15","author":"Bert","year":"1996","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.mehy.2014.12.011_b0270","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/jon2000104209","article-title":"Acute optic neuritis: association with paranasal sinus inflammatory changes on magnetic resonance imaging","volume":"10","author":"Ergene","year":"2000","journal-title":"J Neuroimag"},{"key":"10.1016\/j.mehy.2014.12.011_b0275","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.mehy.2004.07.024","article-title":"A possible link between multiple sclerosis and Creutzfeldt\u2013Jakob disease based on clinical, genetic, pathological and immunological evidence involving Acinetobacter bacteria","volume":"64","author":"Ebringer","year":"2005","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.mehy.2014.12.011_b0280","doi-asserted-by":"crossref","first-page":"243","DOI":"10.4161\/viru.19700","article-title":"Acinetobacter baumannii: an emerging opportunistic pathogen","volume":"3","author":"Howard","year":"2012","journal-title":"Virulence"},{"key":"10.1016\/j.mehy.2014.12.011_b0285","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.mehy.2006.06.017","article-title":"From rabies to transmissible spongiform encephalopathies: An immune mediated microbial trigger involving molecular mimicry could be the answer","volume":"68","author":"Ebringer","year":"2007","journal-title":"Med Hypotheses"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987714004551?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987714004551?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T04:34:43Z","timestamp":1690778083000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987714004551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":57,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S0306987714004551"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2014.12.011","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fundamental immunological problems associated with \u201ctransmissible spongiform encephalopathies\u201d","name":"articletitle","label":"Article Title"},{"value":"Medical Hypotheses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mehy.2014.12.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}