{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T20:18:41Z","timestamp":1747167521498,"version":"3.40.5"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Science and Innovation Fund of Shenzhen","award":["JCYJ20150331142757390"],"award-info":[{"award-number":["JCYJ20150331142757390"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.mehy.2019.02.020","type":"journal-article","created":{"date-parts":[[2019,2,10]],"date-time":"2019-02-10T05:29:49Z","timestamp":1549776589000},"page":"118-120","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Magnesium sulfate \u2013 An effective agent could delay the progression of fulminant malignant hyperthermia"],"prefix":"10.1016","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5042-0578","authenticated-orcid":false,"given":"Xuebing","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2019.02.020_b0005","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0140-6736(60)92690-8","article-title":"Anaesthetic deaths in a family","volume":"2","author":"Denborough","year":"1960","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.mehy.2019.02.020_b0010","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/s12630-018-1108-0","article-title":"Updated guide for the management of malignant hyperthermia","volume":"65","author":"Riazi","year":"2018","journal-title":"Can J Anaesth"},{"issue":"9134","key":"10.1016\/j.mehy.2019.02.020_b0015","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/S0140-6736(98)03078-5","article-title":"Malignant hyperthermia","volume":"352","author":"Denborough","year":"1998","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.mehy.2019.02.020_b0020","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1460-9592.2011.03774.x","article-title":"Current state of malignant hyperthermia in China mainland: a less optimistic reality","volume":"22","author":"Huang","year":"2012","journal-title":"Paediatr Anaesth"},{"issue":"5","key":"10.1016\/j.mehy.2019.02.020_b0025","doi-asserted-by":"crossref","first-page":"391","DOI":"10.4097\/kjae.2012.63.5.391","article-title":"Malignant hyperthermia","volume":"63","author":"Kim","year":"2012","journal-title":"Korean J Anesthesiol"},{"issue":"2","key":"10.1016\/j.mehy.2019.02.020_b0030","doi-asserted-by":"crossref","first-page":"212","DOI":"10.4103\/0019-5049.96327","article-title":"Malignant hyperthermia: dantrolene sodium \u2013 a must have","volume":"56","author":"Sharma","year":"2012","journal-title":"Indian J Anaesth"},{"issue":"1","key":"10.1016\/j.mehy.2019.02.020_b0035","article-title":"Malignant hyperthermia in Brazil: analysis of hotline activity in 2009","volume":"63","author":"da Silva","year":"2013","journal-title":"Braz J Anesthesiol"},{"issue":"10","key":"10.1016\/j.mehy.2019.02.020_b0040","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s00101-017-0335-z","article-title":"Stocks of dantrolene in anesthesia and intensive care units in Germany: Nationwide online survey with 1673 participants","volume":"66","author":"Pfenninger","year":"2017","journal-title":"Anaesthesist"},{"key":"10.1016\/j.mehy.2019.02.020_b0045","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF03004694","article-title":"Malignant hyperthermia: a statistical review","volume":"17","author":"Britt","year":"1970","journal-title":"Can Anaesth Soc J"},{"issue":"1","key":"10.1016\/j.mehy.2019.02.020_b0050","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1085\/jgp.100.1.115","article-title":"Effects of low myoplasmic Mg2+ on calcium binding by parvalbumin and calcium uptake by the sarcoplasmic reticulum in frog skeletal muscle","volume":"100","author":"Jacquemond","year":"1992","journal-title":"J Gen Physiol"},{"issue":"Pt 2","key":"10.1016\/j.mehy.2019.02.020_b0055","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1113\/jphysiol.1994.sp020253","article-title":"Effects of intracellular pH and [Mg2+] on excitation-contraction coupling in skeletal muscle fibres of the rat","volume":"478","author":"Lamb","year":"1994","journal-title":"J Physiol"},{"issue":"2\u20133","key":"10.1016\/j.mehy.2019.02.020_b0060","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0014-5793(95)00047-D","article-title":"Involvement of Mg2+ in terminating Ca2+ release in cultured rat skeletal muscle","volume":"359","author":"Suda","year":"1995","journal-title":"FEBS Lett"},{"issue":"18","key":"10.1016\/j.mehy.2019.02.020_b0065","doi-asserted-by":"crossref","first-page":"4811","DOI":"10.1073\/pnas.1619835114","article-title":"Dantrolene requires Mg2+ to arrest malignant hyperthermia","volume":"114","author":"Choi","year":"2017","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2","key":"10.1016\/j.mehy.2019.02.020_b0070","first-page":"79","article-title":"Malignant hyperthermia: the clinical syndrome","volume":"41","author":"Ranklev-Twetman","year":"1990","journal-title":"Acta Anaesthesiol Belg"},{"key":"10.1016\/j.mehy.2019.02.020_b0075","first-page":"700","article-title":"Incidence of malignant hyperthermia in Denmark","volume":"64","author":"Ording","year":"1985","journal-title":"Anesth Analg"},{"issue":"2","key":"10.1016\/j.mehy.2019.02.020_b0080","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s00540-006-0495-5","article-title":"Fulminant-type malignant hyperthermia in Japan: cumulative analysis of 383 cases","volume":"21","author":"Migita","year":"2007","journal-title":"J Anesth"},{"key":"10.1016\/j.mehy.2019.02.020_b0085","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s13023-015-0310-1","article-title":"Malignant hyperthermia: a review","volume":"10","author":"Rosenberg","year":"2015","journal-title":"Orphanet J Rare Dis"},{"issue":"1","key":"10.1016\/j.mehy.2019.02.020_b0090","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1097\/00000542-197601000-00008","article-title":"Halothane-induced porcine malignant hyperthermia: metabolic and hemodynamic changes","volume":"44","author":"Gronert","year":"1976","journal-title":"Anesthesiology"},{"issue":"4","key":"10.1016\/j.mehy.2019.02.020_b0095","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/bja\/48.4.297","article-title":"Porcine malignant hyperthermia. I: metabolic and physiological changes","volume":"48","author":"Lucke","year":"1976","journal-title":"Br J Anaesth"},{"issue":"9","key":"10.1016\/j.mehy.2019.02.020_b0100","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/bja\/48.9.831","article-title":"Porcine malignant hyperthermia. III: adrenergic blockade","volume":"48","author":"Lister","year":"1976","journal-title":"Br J Anaesth"},{"issue":"2","key":"10.1016\/j.mehy.2019.02.020_b0105","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1113\/jphysiol.1963.sp007150","article-title":"The mechanism of catecholamine release from the adrenal medulla and the role of calcium in stimulus-secretion coupling","volume":"167","author":"Douglas","year":"1963","journal-title":"J Physiol"},{"issue":"2","key":"10.1016\/j.mehy.2019.02.020_b0110","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1254\/jjp.17.199","article-title":"Stimulatory effect of adenosine triphosphate and magensium on the release of catecholamines from adrenal medullary granules","volume":"17","author":"Oka","year":"1967","journal-title":"Jpn J Pharmacol"},{"issue":"9545","key":"10.1016\/j.mehy.2019.02.020_b0115","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/S0140-6736(06)69444-0","article-title":"Magnesium sulphate for treatment of severe tetanus: a randomised controlled trial","volume":"368","author":"Thwaites","year":"2006","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.mehy.2019.02.020_b0120","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1093\/bja\/62.6.616","article-title":"Use of magnesium sulphate in the anaesthetic management of phaeochromocytoma: a review of 17 anaesthetics","volume":"62","author":"James","year":"1989","journal-title":"Br J Anaesth"},{"issue":"4","key":"10.1016\/j.mehy.2019.02.020_b0125","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1213\/00000539-199810000-00012","article-title":"The effect of magnesium sulphate on hemodynamics and its efficacy in attenuating the response to endotracheal intubation in patients with coronary artery disease","volume":"87","author":"Puri","year":"1998","journal-title":"Anesth Analg"},{"issue":"4","key":"10.1016\/j.mehy.2019.02.020_b0130","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/bja\/aep196","article-title":"Magnesium sulphate attenuates arterial pressure increase during laparoscopic cholecystectomy","volume":"103","author":"Jee","year":"2009","journal-title":"Br J Anaesth"},{"issue":"2","key":"10.1016\/j.mehy.2019.02.020_b0135","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.autneu.2013.03.004","article-title":"Effects of intravenous magnesium infusion on in vivo release of acetylcholine and catecholamine in rat adrenal medulla","volume":"177","author":"Komaki","year":"2013","journal-title":"Auton Neurosci"},{"issue":"4","key":"10.1016\/j.mehy.2019.02.020_b0140","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1016\/S0006-3495(97)78222-5","article-title":"Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia","volume":"73","author":"Laver","year":"1997","journal-title":"Biophys J"},{"issue":"1","key":"10.1016\/j.mehy.2019.02.020_b0145","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.abb.2006.03.001","article-title":"Defective Mg2+ regulation of RyR1 as a causal factor in malignant hyperthermia","volume":"458","author":"Steele","year":"2007","journal-title":"Arch Biochem Biophys"},{"issue":"3","key":"10.1016\/j.mehy.2019.02.020_b0150","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1093\/bja\/ael179","article-title":"Mg2+ dependence of Ca2+ release from the sarcoplasmic reticulum induced by sevoflurane or halothane in skeletal muscle from humans susceptible to malignant hyperthermia","volume":"97","author":"Duke","year":"2006","journal-title":"Br J Anaesth"},{"issue":"1","key":"10.1016\/j.mehy.2019.02.020_b0155","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/00000542-199007000-00016","article-title":"The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine","volume":"73","author":"Lopez","year":"1990","journal-title":"Anesthesiology"},{"issue":"4","key":"10.1016\/j.mehy.2019.02.020_b0160","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/BF03007458","article-title":"In vivo and in vitro responses to magnesium sulphate in porcine malignant hyperthermia","volume":"27","author":"Flewellen","year":"1980","journal-title":"Can Anaesth Soc J"},{"issue":"5","key":"10.1016\/j.mehy.2019.02.020_b0165","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1213\/ANE.0b013e31821263d6","article-title":"Magnesium does not influence the clinical course of succinylcholine-induced malignant hyperthermia","volume":"112","author":"Metterlein","year":"2011","journal-title":"Anesth Analg"},{"issue":"3","key":"10.1016\/j.mehy.2019.02.020_b0170","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1365-2044.1975.tb00861.x","article-title":"Treatment of porcine malignant hyperthermia. A review based on experimental studies","volume":"30","author":"Hall","year":"1975","journal-title":"Anaesthesia"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987718307187?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987718307187?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,9,11]],"date-time":"2022-09-11T17:31:56Z","timestamp":1662917516000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987718307187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":34,"alternative-id":["S0306987718307187"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2019.02.020","relation":{},"ISSN":["0306-9877"],"issn-type":[{"type":"print","value":"0306-9877"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Magnesium sulfate \u2013 An effective agent could delay the progression of fulminant malignant hyperthermia","name":"articletitle","label":"Article Title"},{"value":"Medical Hypotheses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mehy.2019.02.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}