{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T15:16:39Z","timestamp":1767626199520,"version":"build-2065373602"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100014895","name":"Southwest Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010032","name":"Health and Family Planning Commission of Sichuan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010032","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.mehy.2020.109643","type":"journal-article","created":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T11:41:10Z","timestamp":1582717270000},"page":"109643","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Carcinogenesis and precancerosis transformation of chronic osteomyelitis: 6 cases report and literature review"],"prefix":"10.1016","volume":"140","author":[{"given":"Lin","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhao","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianrong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mehy.2020.109643_b0005","doi-asserted-by":"crossref","first-page":"586","DOI":"10.5435\/JAAOS-22-09-586","article-title":"Malignant transformation in chronic osteomyelitis: recognition and principles of management","volume":"22","author":"Panteli","year":"2014","journal-title":"J Am Acad Orthop Surg."},{"key":"10.1016\/j.mehy.2020.109643_b0010","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0140-6736(04)16727-5","article-title":"Osteomyelitis","volume":"364","author":"Lew","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.mehy.2020.109643_b0015","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.rbo.2016.04.007","article-title":"Malignant transformation in chronic osteomyelitis","volume":"52","author":"Moura","year":"2017","journal-title":"Rev Bras Ortop"},{"key":"10.1016\/j.mehy.2020.109643_b0020","article-title":"Malignant lesions arising in chronic osteomyelitis","volume":"181\u2013189","author":"McGrory","year":"1999","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.mehy.2020.109643_b0025","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1177\/107110070402501109","article-title":"Squamous cell carcinoma arising in chronic osteomyelitis in foot and ankle","volume":"25","author":"Altay","year":"2004","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.mehy.2020.109643_b0030","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/s13256-016-1002-8","article-title":"Squamous cell carcinoma in chronic osteomyelitis: a case report and review of the literature","volume":"10","author":"Caruso","year":"2016","journal-title":"J Med Case Rep"},{"key":"10.1016\/j.mehy.2020.109643_b0035","first-page":"10178","article-title":"Squamous cell carcinoma resulting from chronic osteomyelitis: a retrospective study of 8 cases","volume":"8","author":"Li","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"10.1016\/j.mehy.2020.109643_b0040","first-page":"327","article-title":"Malignant transformation of chronic osteomyelitis and its scar tissue: Apropos of 3 cases","volume":"59","author":"Gebhart","year":"1993","journal-title":"Acta Orthop Belg"},{"key":"10.1016\/j.mehy.2020.109643_b0045","doi-asserted-by":"crossref","first-page":"162","DOI":"10.2106\/00004623-197355010-00017","article-title":"Sarcomas arising from chronic osteomyelitic sinuses. A report of two cases","volume":"55","author":"Johnston","year":"1973","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.mehy.2020.109643_b0050","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1302\/0301-620X.33B2.167","article-title":"Cancer as a sequel to war wounds","volume":"33B","author":"Gillis","year":"1951","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.mehy.2020.109643_b0055","first-page":"174","article-title":"Marjolin's ulcer: Incidental diagnosis of squamous cell carcinoma on hemipelvectomy for recalcitrant pelvic osteomyelitis","volume":"30","author":"Lack","year":"2010","journal-title":"Iowa Orthop J"},{"key":"10.1016\/j.mehy.2020.109643_b0060","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1056\/NEJM199704033361406","article-title":"Osteomyelitis","volume":"336","author":"Lew","year":"1997","journal-title":"N Engl J Med"},{"issue":"8","key":"10.1016\/j.mehy.2020.109643_b0065","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.36740\/WLek201908124","article-title":"The role of adipose tissue with particular emphasis on cytokines in the pathogenesis of neoplastic diseases","volume":"72","author":"Warakomski","year":"2019","journal-title":"Wiad Lek"},{"issue":"2","key":"10.1016\/j.mehy.2020.109643_b0070","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41591-019-0737-3","article-title":"Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma","volume":"26","author":"Brudno","year":"2020","journal-title":"Nat Med"},{"key":"10.1016\/j.mehy.2020.109643_b0075","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00508-008-1104-4","article-title":"Verrucous carcinoma of the tibia arising after chronic osteomyelitis: a case report","volume":"121","author":"Wolf","year":"2009","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.mehy.2020.109643_b0080","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3944\/AOTT.2011.2537","article-title":"Squamous cell carcinoma arising from chronic osteomyelitis","volume":"45","author":"Alami","year":"2011","journal-title":"Acta Orthop Traumatol Turc"},{"key":"10.1016\/j.mehy.2020.109643_b0085","first-page":"702","article-title":"Squamous cell carcinoma derived from osteomyelitis in plateau area: 6 cases report","volume":"14","author":"Tang","year":"1994","journal-title":"Chin J Orthop"},{"key":"10.1016\/j.mehy.2020.109643_b0090","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00129334-200301000-00014","article-title":"Wounds and malignancy","volume":"16","author":"Trent","year":"2003","journal-title":"Adv Skin Wound Care"},{"key":"10.1016\/j.mehy.2020.109643_b0095","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1053\/crad.2002.1137","article-title":"Fibroblastic osteosarcoma arising in chronic osteomyelitis","volume":"58","author":"Puri","year":"2003","journal-title":"Clin Radiol"},{"key":"10.1016\/j.mehy.2020.109643_b0100","first-page":"249","article-title":"Musculocutaneous flap could be good alternative for defect reconstruction after chronic leg ulcer excision","volume":"4","author":"Genmao Ye","year":"1990","journal-title":"Chin J Reconstruct Surg"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987719313957?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987719313957?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:20:44Z","timestamp":1759692044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987719313957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":20,"alternative-id":["S0306987719313957"],"URL":"https:\/\/doi.org\/10.1016\/j.mehy.2020.109643","relation":{},"ISSN":["0306-9877"],"issn-type":[{"type":"print","value":"0306-9877"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Carcinogenesis and precancerosis transformation of chronic osteomyelitis: 6 cases report and literature review","name":"articletitle","label":"Article Title"},{"value":"Medical Hypotheses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mehy.2020.109643","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109643"}}