{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:45:44Z","timestamp":1777448744926,"version":"3.51.4"},"reference-count":49,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","metabolismjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Metabolism"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.metabol.2004.07.011","type":"journal-article","created":{"date-parts":[[2004,12,15]],"date-time":"2004-12-15T08:15:47Z","timestamp":1103098547000},"page":"60-66","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Adiponectin and glucose production in patients infected with Plasmodium falciparum"],"prefix":"10.1016","volume":"54","author":[{"given":"Regje M.E.","family":"Bl\u00fcmer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huynh","family":"van Thien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An F.C.","family":"Ruiter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerrit-Jan","family":"Weverling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dang","family":"vinh Thuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Endert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piet A.","family":"Kager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans P.","family":"Sauerwein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.metabol.2004.07.011_bib1","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1038\/sj.ijo.0800770","article-title":"Adipose tissue as an endocrine and paracrine organ","volume":"22","author":"Mohamed-Ali","year":"1998","journal-title":"Int. J. Obes. Relat. Metab. Disord."},{"key":"10.1016\/j.metabol.2004.07.011_bib2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S1043-2760(00)00301-5","article-title":"Adipose tissue as an endocrine organ","volume":"11","author":"Ahima","year":"2000","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib3","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1172\/JCI14120","article-title":"Endogenous glucose production is inhibited by the adipose-derived protein Acrp30","volume":"108","author":"Combs","year":"2001","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.metabol.2004.07.011_bib4","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1073\/pnas.98.4.2005","article-title":"Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice","volume":"98","author":"Fruebis","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.metabol.2004.07.011_bib5","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/90984","article-title":"The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity","volume":"7","author":"Yamauchi","year":"2001","journal-title":"Nat. Med."},{"key":"10.1016\/j.metabol.2004.07.011_bib6","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1210\/jcem.86.5.7463","article-title":"Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia","volume":"86","author":"Weyer","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib7","doi-asserted-by":"crossref","first-page":"3315","DOI":"10.2337\/diacare.26.12.3315","article-title":"Plasma adiponectin and endogenous glucose production in humans","volume":"26","author":"Stefan","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.metabol.2004.07.011_bib8","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/bbrc.1999.0255","article-title":"Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity","volume":"257","author":"Arita","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.metabol.2004.07.011_bib9","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1161\/01.ATV.20.6.1595","article-title":"Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients","volume":"20","author":"Hotta","year":"2000","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.metabol.2004.07.011_bib10","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1097\/00126334-200212150-00009","article-title":"Adiponectin and leptin levels in HIV-infected subjects with insulin resistance and body fat redistribution","volume":"31","author":"Mynarcik","year":"2002","journal-title":"J. Acquir. Immune Defic. Syndr."},{"key":"10.1016\/j.metabol.2004.07.011_bib11","doi-asserted-by":"crossref","first-page":"3770","DOI":"10.1210\/jcem.85.10.6914","article-title":"Insulin resistance and substrate utilization in human endotoxemia","volume":"85","author":"Agwunobi","year":"2000","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib12","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1042\/cs0990321","article-title":"Insulin sensitivity of glucose and fat metabolism in severe sepsis","volume":"99","author":"Chambrier","year":"2000","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.metabol.2004.07.011_bib13","first-page":"551","article-title":"Inflammatory status and insulin resistance","volume":"5","author":"Grimble","year":"2002","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.metabol.2004.07.011_bib14","first-page":"S24","article-title":"Regulation of lipid metabolism by cytokines during host defense","volume":"12","author":"Grunfeld","year":"1996","journal-title":"Nutrition"},{"key":"10.1016\/j.metabol.2004.07.011_bib15","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/0024-3205(89)90423-2","article-title":"Insulin resistance in septic rats-a study by the euglycemic clamp technique","volume":"45","author":"Iochida","year":"1989","journal-title":"Life Sci."},{"key":"10.1016\/j.metabol.2004.07.011_bib16","first-page":"425","article-title":"In vivo skeletal muscle insulin resistance during E coli endotoxin shock in the dog","volume":"8","author":"Raymond","year":"1981","journal-title":"Circ. Shock"},{"key":"10.1016\/j.metabol.2004.07.011_bib17","doi-asserted-by":"crossref","first-page":"53S","DOI":"10.1177\/014860718801200604","article-title":"Alterations in lipid and carbohydrate metabolism in sepsis","volume":"12","author":"Spitzer","year":"1988","journal-title":"JPEN J. Parenter. Enteral Nutr."},{"key":"10.1016\/j.metabol.2004.07.011_bib18","first-page":"E1059","article-title":"Glucose production and gluconeogenesis in adults with uncomplicated falciparum malaria","volume":"272","author":"Dekker","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.metabol.2004.07.011_bib19","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1093\/qjmed\/91.3.191","article-title":"Hypoglycaemia on and after admission in Kenyan children with severe malaria","volume":"91","author":"English","year":"1998","journal-title":"QJM"},{"key":"10.1016\/j.metabol.2004.07.011_bib20","doi-asserted-by":"crossref","first-page":"119","DOI":"10.4269\/ajtmh.1996.55.119","article-title":"Severe and complicated falciparum malaria in Melanesian adults in Papua New Guinea","volume":"55","author":"Lalloo","year":"1996","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.metabol.2004.07.011_bib21","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/qjmed\/94.12.709","article-title":"Glucose production and gluconeogenesis in adults with cerebral malaria","volume":"94","author":"van Thien","year":"2001","journal-title":"QJM"},{"key":"10.1016\/j.metabol.2004.07.011_bib22","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1056\/NEJM198307143090201","article-title":"Severe hypoglycemia and hyperinsulinemia in falciparum malaria","volume":"309","author":"White","year":"1983","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.metabol.2004.07.011_bib23","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/S0026-0495(97)90144-X","article-title":"Glucose metabolism in severe malaria: minimal model analysis of the intravenous glucose tolerance test incorporating a stable glucose label","volume":"46","author":"Binh","year":"1997","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2004.07.011_bib24","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/0026-0495(94)90272-0","article-title":"Glycerol metabolism in severe falciparum malaria","volume":"43","author":"Pukrittayakamee","year":"1994","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2004.07.011_bib25","doi-asserted-by":"crossref","first-page":"E609","DOI":"10.1152\/ajpendo.00026.2004","article-title":"Free fatty acids are not involved in the regulation of gluconeogenesis and glycogenolysis in adults with uncomplicated P. falciparum malaria","author":"van Thien","year":"2004","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib26","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1055\/s-2007-979047","article-title":"Stable isotope techniques for the study of gluconeogenesis in man","volume":"29","author":"Landau","year":"1997","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.metabol.2004.07.011_bib27","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1017\/S0029665199001275","article-title":"Quantifying the contribution of gluconeogenesis to glucose production in fasted human subjects using stable isotopes","volume":"58","author":"Landau","year":"1999","journal-title":"Proc. Nutr. Soc."},{"key":"10.1016\/j.metabol.2004.07.011_bib28","first-page":"461","article-title":"Methods for measuring gluconeogenesis in vivo","volume":"1","author":"Previs","year":"1998","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.metabol.2004.07.011_bib29","first-page":"505","article-title":"Determination of glucose turnover and glucose oxidation rates in man with stable isotope tracers","volume":"28","author":"Reinauer","year":"1990","journal-title":"J. Clin. Chem. Clin. Biochem."},{"key":"10.1016\/j.metabol.2004.07.011_bib30","first-page":"2220","article-title":"The quantification of gluconeogenesis in healthy men by (2)H2O and [2-(13)C]glycerol yields different results: rates of gluconeogenesis in healthy men measured with (2)H2O are higher than those measured with [2-(13)C]glycerol","volume":"86","author":"Ackermans","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib31","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1172\/JCI118803","article-title":"Contributions of gluconeogenesis to glucose production in the fasted state","volume":"98","author":"Landau","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.metabol.2004.07.011_bib32","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1002\/(SICI)1096-9888(199606)31:6<639::AID-JMS336>3.0.CO;2-S","article-title":"Assay of the deuterium enrichment of water via acetylene","volume":"31","author":"Previs","year":"1996","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.metabol.2004.07.011_bib33","series-title":"Radioactive and stable isotope tracers in biomedicine: principles and practice of kinetic analysis","author":"Wolfe","year":"1992"},{"key":"10.1016\/j.metabol.2004.07.011_bib34","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1046\/j.1463-1326.2003.00254.x","article-title":"Fasting serum adiponectin concentration is reduced in Indo-Asian subjects and is related to HDL cholesterol","volume":"5","author":"Valsamakis","year":"2003","journal-title":"Diabetes Obes. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib35","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S1388-1981(02)00298-6","article-title":"Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of beta3-adrenergic agonists, retinoic acid, leptin and fasting","volume":"1584","author":"Zhang","year":"2002","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.metabol.2004.07.011_bib36","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1046\/j.1365-2249.2003.02264.x","article-title":"Circulating adiponectin levels during human endotoxaemia","volume":"134","author":"Keller","year":"2003","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.metabol.2004.07.011_bib37","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S1286-4579(02)01541-1","article-title":"Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis","volume":"4","author":"de Souza","year":"2002","journal-title":"Microbes Infect."},{"key":"10.1016\/j.metabol.2004.07.011_bib38","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1172\/JCI0215736","article-title":"Selective parasympathetic innervation of subcutaneous and intra-abdominal fat-functional implications","volume":"110","author":"Kreier","year":"2002","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.metabol.2004.07.011_bib39","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1083\/jcb.146.3.609","article-title":"Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4","volume":"146","author":"Bogan","year":"1999","journal-title":"J. Cell. Biol."},{"key":"10.1016\/j.metabol.2004.07.011_bib40","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1006\/bbrc.2001.5904","article-title":"Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue","volume":"288","author":"Halleux","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.metabol.2004.07.011_bib41","doi-asserted-by":"crossref","first-page":"5662","DOI":"10.1210\/jc.2002-020635","article-title":"Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone","volume":"87","author":"Motoshima","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib42","doi-asserted-by":"crossref","first-page":"26746","DOI":"10.1074\/jbc.270.45.26746","article-title":"A novel serum protein similar to C1q, produced exclusively in adipocytes","volume":"270","author":"Scherer","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.metabol.2004.07.011_bib43","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1006\/bbrc.2001.6307","article-title":"Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes","volume":"290","author":"Fasshauer","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.metabol.2004.07.011_bib44","doi-asserted-by":"crossref","first-page":"E1266","DOI":"10.1152\/ajpendo.00227.2002","article-title":"Adiponectin is stimulated by adrenalectomy in ob\/ob mice and is highly correlated with resistin mRNA","volume":"283","author":"Makimura","year":"2002","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib45","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1210\/jc.2002-021215","article-title":"Anorexia nervosa is characterized by increased adiponectin plasma levels and reduced nonoxidative glucose metabolism","volume":"88","author":"Pannacciulli","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.metabol.2004.07.011_bib46","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1046\/j.1365-2265.2003.01789.x","article-title":"Perturbations in adiponectin, leptin and resistin levels in acromegaly: lack of correlation with insulin resistance","volume":"58","author":"Silha","year":"2003","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"10.1016\/j.metabol.2004.07.011_bib47","doi-asserted-by":"crossref","first-page":"12152","DOI":"10.1074\/jbc.M311113200","article-title":"Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity","volume":"279","author":"Pajvani","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.metabol.2004.07.011_bib48","doi-asserted-by":"crossref","first-page":"50810","DOI":"10.1074\/jbc.M309469200","article-title":"Role of disulfide bonds in Acrp30\/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways","volume":"278","author":"Tsao","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.metabol.2004.07.011_bib49","doi-asserted-by":"crossref","first-page":"40352","DOI":"10.1074\/jbc.M300365200","article-title":"Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin","volume":"278","author":"Waki","year":"2003","journal-title":"J. Biol. Chem."}],"container-title":["Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049504003051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049504003051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T02:45:35Z","timestamp":1758422735000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026049504003051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0026049504003051"],"URL":"https:\/\/doi.org\/10.1016\/j.metabol.2004.07.011","relation":{},"ISSN":["0026-0495"],"issn-type":[{"value":"0026-0495","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adiponectin and glucose production in patients infected with Plasmodium falciparum","name":"articletitle","label":"Article Title"},{"value":"Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.metabol.2004.07.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}