{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T09:13:45Z","timestamp":1774343625468,"version":"3.50.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","metabolismjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Metabolism"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1016\/j.metabol.2006.01.004","type":"journal-article","created":{"date-parts":[[2006,4,27]],"date-time":"2006-04-27T11:37:09Z","timestamp":1146137829000},"page":"669-675","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Persistent suppression of resting energy expenditure after acute hypoxia"],"prefix":"10.1016","volume":"55","author":[{"given":"Kerstin M.","family":"Oltmanns","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hartmut","family":"Gehring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Rudolf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Schultes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Schweiger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Born","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Horst L.","family":"Fehm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achim","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl 1","key":"10.1016\/j.metabol.2006.01.004_bib1","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1007\/PL00014266","article-title":"Assessment of energy expenditure in metabolic disorders","volume":"156","author":"Bodamer","year":"1997","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.metabol.2006.01.004_bib2","doi-asserted-by":"crossref","first-page":"11080","DOI":"10.1073\/pnas.97.20.11080","article-title":"High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia","volume":"97","author":"Gnaiger","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.metabol.2006.01.004_bib3","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1093\/sleep\/18.3.180","article-title":"Energy expenditure in obstructive sleep apnea","volume":"18","author":"Ryan","year":"1995","journal-title":"Sleep"},{"key":"10.1016\/j.metabol.2006.01.004_bib4","first-page":"E1036","article-title":"Energy expenditure in obstructive sleep apnea: effects of treatment with continuous positive airway pressure","volume":"271","author":"Stenlof","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1016\/j.metabol.2006.01.004_bib5","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1053\/meta.2002.31969","article-title":"Effects of treatment by laser-assisted uvuloplasty on sleep energy expenditure in obstructive sleep apnea patients","volume":"51","author":"Lin","year":"2002","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2006.01.004_bib6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s005920170023","article-title":"Pathogenesis of obesity and diabetes mellitus: insights provided by indirect calorimetry in humans","volume":"38","author":"Perseghin","year":"2001","journal-title":"Acta Diabetol"},{"key":"10.1016\/j.metabol.2006.01.004_bib7","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s004249900203","article-title":"Operation Everest III: energy and water balance","volume":"439","author":"Westerterp","year":"2000","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.metabol.2006.01.004_bib8","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/978-1-4757-3401-0_16","article-title":"Weight loss at high altitude","volume":"502","author":"Tschop","year":"2001","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.metabol.2006.01.004_bib9","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1152\/jappl.1999.87.6.2053","article-title":"Blood pressure and plasma catecholamines in acute and prolonged hypoxia: effects of local hypothermia","volume":"87","author":"Kanstrup","year":"1999","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.metabol.2006.01.004_bib10","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1152\/jappl.2001.91.2.623","article-title":"Women at altitude: short-term exposure to hypoxia and\/or alpha(1)- adrenergic blockade reduces insulin sensitivity","volume":"91","author":"Braun","year":"2001","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.metabol.2006.01.004_bib11","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1152\/jappl.2001.90.1.121","article-title":"Catecholamine responses to alpha-adrenergic blockade during exercise in women acutely exposed to altitude","volume":"90","author":"Mazzeo","year":"2001","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.metabol.2006.01.004_bib12","doi-asserted-by":"crossref","first-page":"249S","DOI":"10.1093\/ajcn\/55.1.249s","article-title":"Thermogenic effects of various beta-adrenoceptor agonists in humans: their potential usefulness in the treatment of obesity","volume":"55","author":"Jequier","year":"1992","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.metabol.2006.01.004_bib13","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0300-595X(84)80039-0","article-title":"The role of thyroid hormones in the control of energy expenditure","volume":"13","author":"Danforth","year":"1984","journal-title":"Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2006.01.004_bib14","doi-asserted-by":"crossref","first-page":"224S","DOI":"10.1093\/ajcn\/56.1.224S","article-title":"Factors determining energy expenditure during very-low-calorie diets","volume":"56","author":"Van Gaal","year":"1992","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.metabol.2006.01.004_bib15","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1055\/s-0028-1092699","article-title":"Effect of acute hypoxia on blood TSH levels","volume":"11","author":"Curbelo","year":"1979","journal-title":"Horm Metab Res"},{"key":"10.1016\/j.metabol.2006.01.004_bib16","first-page":"53","article-title":"Modifications of the pituitary-thyroid axis induced by hypobaric hypoxia","volume":"32","author":"Varela","year":"1982","journal-title":"Acta Physiol Lat Am"},{"key":"10.1016\/j.metabol.2006.01.004_bib17","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1152\/jappl.1982.53.2.313","article-title":"Altitude-induced changes in plasma thyroxine, 3,5,3\u2032-triiodothyronine, and thyrotropin in rats","volume":"53","author":"Connors","year":"1982","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.metabol.2006.01.004_bib18","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/BF01048714","article-title":"Thyroid function during intermittent exposure to hypobaric hypoxia","volume":"34","author":"Sawhney","year":"1990","journal-title":"Int J Biometeorol"},{"key":"10.1016\/j.metabol.2006.01.004_bib19","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1081\/ERC-120022301","article-title":"Endocrine changes in a rat model of chronic hypoxia mimicking cyanotic heart disease","volume":"29","author":"Zayour","year":"2003","journal-title":"Endocr Res"},{"key":"10.1016\/j.metabol.2006.01.004_bib20","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1677\/joe.0.1090119","article-title":"Morphological changes in the pituitary and thyroid of the rat in hypobaric hypoxia","volume":"109","author":"Gosney","year":"1986","journal-title":"J Endocrinol"},{"key":"10.1016\/j.metabol.2006.01.004_bib21","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0026-0495(88)90110-2","article-title":"The theoretical bases of indirect calorimetry: a review","volume":"37","author":"Ferrannini","year":"1988","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2006.01.004_bib22","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1046\/j.1365-201X.1998.00405.x","article-title":"The influence of PaO2, pH and SaO2 on maximal oxygen uptake","volume":"164","author":"Nielsen","year":"1998","journal-title":"Acta Physiol Scand"},{"key":"10.1016\/j.metabol.2006.01.004_bib23","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1164\/rccm.200308-1200OC","article-title":"Hypoxia causes glucose intolerance in humans","volume":"169","author":"Oltmanns","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.metabol.2006.01.004_bib24","first-page":"437","article-title":"Mechanisms of adaptation to hypoxia in energy metabolism in rats","volume":"181","author":"Mimura","year":"1995","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.metabol.2006.01.004_bib25","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1136\/thx.34.6.783","article-title":"Diet, absorption, and hormone studies in relation to body weight in obstructive airways disease","volume":"34","author":"d'A Semple","year":"1979","journal-title":"Thorax"},{"key":"10.1016\/j.metabol.2006.01.004_bib26","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1136\/thx.36.8.605","article-title":"Hypothalamic-pituitary dysfunction in respiratory hypoxia","volume":"36","author":"Semple","year":"1981","journal-title":"Thorax"},{"key":"10.1016\/j.metabol.2006.01.004_bib27","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1136\/thx.42.7.520","article-title":"Thyroid function and endocrine abnormalities in elderly patients with severe chronic obstructive lung disease","volume":"42","author":"Gow","year":"1987","journal-title":"Thorax"},{"key":"10.1016\/j.metabol.2006.01.004_bib28","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1053\/rmed.2000.0953","article-title":"Impact of hypoxaemia on neuroendocrine function and catecholamine secretion in chronic obstructive pulmonary disease (COPD). Effects of long-term oxygen treatment","volume":"94","author":"Bratel","year":"2000","journal-title":"Respir Med"},{"key":"10.1016\/j.metabol.2006.01.004_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0954-6111(99)90068-9","article-title":"Pituitary reactivity, androgens and catecholamines in obstructive sleep apnoea. Effects of continuous positive airway pressure treatment (CPAP)","volume":"93","author":"Bratel","year":"1999","journal-title":"Respir Med"},{"key":"10.1016\/j.metabol.2006.01.004_bib30","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1046\/j.1365-2796.2003.01212.x","article-title":"Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoea","volume":"254","author":"Meston","year":"2003","journal-title":"J Intern Med"},{"key":"10.1016\/j.metabol.2006.01.004_bib31","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1365-2265.2004.01938.x","article-title":"Obese patients with obstructive sleep apnoea syndrome show a peculiar alteration of the corticotroph but not of the thyrotroph and lactotroph function","volume":"60","author":"Lanfranco","year":"2004","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.metabol.2006.01.004_bib32","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0889-8529(03)00078-1","article-title":"Obesity and endocrine disease","volume":"32","author":"Kokkoris","year":"2003","journal-title":"Endocrinol Metab Clin North Am"},{"key":"10.1016\/j.metabol.2006.01.004_bib33","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/clinchem\/42.1.135","article-title":"Physiological variations in thyroid hormones: physiological and pathophysiological considerations","volume":"42","author":"Fisher","year":"1996","journal-title":"Clin Chem"},{"key":"10.1016\/j.metabol.2006.01.004_bib34","doi-asserted-by":"crossref","first-page":"695","DOI":"10.2337\/diab.44.6.695","article-title":"Hypoxia stimulates glucose transport in insulin-resistant human skeletal muscle","volume":"44","author":"Azevedo","year":"1995","journal-title":"Diabetes"},{"issue":"Pt 1","key":"10.1016\/j.metabol.2006.01.004_bib35","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1113\/jphysiol.2003.048173","article-title":"Intermittent hypoxia increases insulin resistance in genetically obese mice","volume":"552","author":"Polotsky","year":"2003","journal-title":"J Physiol"},{"key":"10.1016\/j.metabol.2006.01.004_bib36","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s001250051341","article-title":"New insights into sympathetic regulation of glucose and fat metabolism","volume":"43","author":"Nonogaki","year":"2000","journal-title":"Diabetologia"},{"key":"10.1016\/j.metabol.2006.01.004_bib37","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.2337\/diacare.24.11.1917","article-title":"Changes in BMI and weight before and after the development of type 2 diabetes","volume":"24","author":"Looker","year":"2001","journal-title":"Diabetes Care"},{"key":"10.1016\/j.metabol.2006.01.004_bib38","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1152\/jappl.2001.91.3.1245","article-title":"Decreased neuronal excitability in hippocampal neurons of mice exposed to cyclic hypoxia","volume":"91","author":"Gu","year":"2001","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.metabol.2006.01.004_bib39","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.neubiorev.2004.03.002","article-title":"The selfish brain: competition for energy resources","volume":"28","author":"Peters","year":"2004","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.metabol.2006.01.004_bib40","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1056\/NEJM197003192821209","article-title":"Starvation in man","volume":"282","author":"Cahill","year":"1970","journal-title":"N Engl J Med"}],"container-title":["Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049506000394?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049506000394?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T03:08:42Z","timestamp":1758424122000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026049506000394"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S0026049506000394"],"URL":"https:\/\/doi.org\/10.1016\/j.metabol.2006.01.004","relation":{},"ISSN":["0026-0495"],"issn-type":[{"value":"0026-0495","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistent suppression of resting energy expenditure after acute hypoxia","name":"articletitle","label":"Article Title"},{"value":"Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.metabol.2006.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}