{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:39:21Z","timestamp":1782254361346,"version":"3.54.5"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","metabolismjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Metabolism"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.metabol.2007.11.014","type":"journal-article","created":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T14:13:58Z","timestamp":1204899238000},"page":"517-521","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Cinacalcet for the treatment of primary hyperparathyroidism"],"prefix":"10.1016","volume":"57","author":[{"given":"Saima","family":"Sajid-Crockett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick R.","family":"Singer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome M.","family":"Hershman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.metabol.2007.11.014_bib1","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1056\/NEJM199910213411701","article-title":"A 10-year prospective study of primary hyperparathyroidism with or without parathyroid surgery","volume":"341","author":"Silverberg","year":"1999","journal-title":"NEJM"},{"key":"10.1016\/j.metabol.2007.11.014_bib2","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1001\/archinte.160.14.2161","article-title":"Effects of hormone replacement therapy on bone mineral density in postmenopausal women with primary hyperparathyroidism","volume":"160","author":"Orr-Walker","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.metabol.2007.11.014_bib3","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00001622-200101000-00007","article-title":"Nonoperative management of hyperparathyroidism: present and future","volume":"13","author":"Weigel","year":"2001","journal-title":"Curr Opin Oncol"},{"key":"10.1016\/j.metabol.2007.11.014_bib4","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/00019616-200111000-00006","article-title":"Alendronate therapy of primary hyperparathyroidism","volume":"11","author":"Hassani","year":"2001","journal-title":"Endocrinologist"},{"key":"10.1016\/j.metabol.2007.11.014_bib5","doi-asserted-by":"crossref","first-page":"633","DOI":"10.7326\/0003-4819-100-5-633","article-title":"Conjugated estrogens in the treatment of postmenopausal women with hyperparathyroidism","volume":"100","author":"Marcus","year":"1984","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.metabol.2007.11.014_bib6","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1210\/jc.2002-020667","article-title":"Raloxifene lowers serum calcium and markers of bone turnover in postmenopausal women with primary hyperparathyroidism","volume":"88","author":"Rubin","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2007.11.014_bib7","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1210\/jc.2002-020890","article-title":"Oral alendronate increases bone mineral density in postmenopausal women with primary hyperparathyroidism","volume":"88","author":"Chow","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2007.11.014_bib8","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1359\/jbmr.2001.16.1.113","article-title":"Effects of oral alendronate in elderly patients with osteoporosis and mild primary hyperparathyroidism","volume":"16","author":"Rossini","year":"2001","journal-title":"J\u00a0Bone Miner Res"},{"key":"10.1016\/j.metabol.2007.11.014_bib9","doi-asserted-by":"crossref","first-page":"4482","DOI":"10.1210\/jc.2001-010385","article-title":"Alendronate in the treatment of primary hyperparathyroid-related osteoporosis: a 2-year study","volume":"87","author":"Parker","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2007.11.014_bib10","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1146\/annurev.med.49.1.15","article-title":"The extracellular calcium-sensing receptor: its role in health and disease","volume":"49","author":"Brown","year":"1998","journal-title":"Ann Rev Med"},{"key":"10.1016\/j.metabol.2007.11.014_bib11","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1517\/13543784.13.3.229","article-title":"Calcium agonists in hyperparathyroidism","volume":"13","author":"Falchetti","year":"2004","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1016\/j.metabol.2007.11.014_bib12","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1517\/13543784.12.8.1413","article-title":"Cinacalcet HCl: a calcimimetic agent for the management of primary and secondary hyperparathyroidism","volume":"12","author":"Franceschini","year":"2003","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1016\/j.metabol.2007.11.014_bib13","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1056\/NEJM199507273330407","article-title":"Calcium-ion\u2013sensing cell-surface receptors","volume":"333","author":"Brown","year":"1995","journal-title":"NEJM"},{"key":"10.1016\/j.metabol.2007.11.014_bib14","first-page":"587","article-title":"Cinacalcet hydrochloride","volume":"6","author":"Iqbal","year":"2003","journal-title":"Amgen Drugs"},{"key":"10.1016\/j.metabol.2007.11.014_bib15","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1097\/00041552-200109000-00005","article-title":"Calcimimetic agents for the treatment of hyperparathyroidism","volume":"10","author":"Goodman","year":"2001","journal-title":"Curr Opin Neph HTN"},{"key":"10.1016\/j.metabol.2007.11.014_bib16","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/00041552-200003000-00005","article-title":"Calcimimetic agents and the calcium-sensing receptor","volume":"9","author":"Coburn","year":"2000","journal-title":"Curr Opin Neph HTN"},{"key":"10.1016\/j.metabol.2007.11.014_bib17","first-page":"470","article-title":"Cinacalcet hydrochloride","volume":"16","year":"2003","journal-title":"Drug News Perspect"},{"key":"10.1016\/j.metabol.2007.11.014_bib18","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/00041552-199907000-00006","article-title":"The calcium receptor and calcimimetics","volume":"8","author":"Wada","year":"1999","journal-title":"Curr Opin Neph HTN"},{"key":"10.1016\/j.metabol.2007.11.014_bib19","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0002-9343(98)00418-5","article-title":"Physiology and pathophysiology of the extracellular calcium-sensing receptor","volume":"106","author":"Brown","year":"1999","journal-title":"Am J Med"},{"issue":"S73","key":"10.1016\/j.metabol.2007.11.014_bib20","doi-asserted-by":"crossref","first-page":"S52","DOI":"10.1046\/j.1523-1755.1999.07303.x","article-title":"Calcium-sensing receptor and calcimimetic agents","volume":"56","author":"Coburn","year":"1999","journal-title":"Kidney Int"},{"key":"10.1016\/j.metabol.2007.11.014_bib21","doi-asserted-by":"crossref","first-page":"5644","DOI":"10.1210\/jc.2002-021597","article-title":"The calcimimetic cinacalcet normalizes serum calcium in subjects with primary hyperparathyroidism","volume":"88","author":"Shoback","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2007.11.014_bib22","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1210\/jc.2004-0842","article-title":"Cinacalcet hydrochloride maintains long-term normocalcemia in patients with primary hyperparathryoidism","volume":"90","author":"Peacock","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2007.11.014_bib23","first-page":"1080","article-title":"Editorial: calcimimetics\u2014new drugs with the potential to control hyperparathyroidism","volume":"83","author":"Ott","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2007.11.014_bib24","doi-asserted-by":"crossref","first-page":"5353","DOI":"10.1210\/jc.2002-021370","article-title":"Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century","volume":"87","author":"Bilezikian","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2007.11.014_bib25","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/00000658-199509000-00017","article-title":"Clinical manifestations of primary hyperparathyroidism before and after parathyroidectomy","volume":"222","author":"Chan","year":"1995","journal-title":"Ann Surg"},{"key":"10.1016\/j.metabol.2007.11.014_bib26","first-page":"729","article-title":"Increased bone mineral density after parathyroidectomy in primary hyperparathyroidism","volume":"80","author":"Silverberg","year":"1995","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049507004088?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049507004088?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T03:24:37Z","timestamp":1758425077000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026049507004088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S0026049507004088"],"URL":"https:\/\/doi.org\/10.1016\/j.metabol.2007.11.014","relation":{},"ISSN":["0026-0495"],"issn-type":[{"value":"0026-0495","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cinacalcet for the treatment of primary hyperparathyroidism","name":"articletitle","label":"Article Title"},{"value":"Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.metabol.2007.11.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}