{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:05:38Z","timestamp":1761512738095,"version":"3.44.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014382","name":"Ipsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014382","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","metabolismjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Metabolism"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.metabol.2009.08.002","type":"journal-article","created":{"date-parts":[[2009,10,3]],"date-time":"2009-10-03T19:45:46Z","timestamp":1254599146000},"page":"350-358","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of glucose and lipid metabolism and bone mineralization in patients with growth hormone deficiency with and without long-term growth hormone replacement"],"prefix":"10.1016","volume":"59","author":[{"given":"Josefine","family":"Roemmler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maren","family":"Kuenkler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harald J.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Dieterle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Schopohl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8 Pt 1","key":"10.1016\/j.metabol.2009.08.002_bib1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.2337\/diab.31.8.663","article-title":"Effects of growth hormone on insulin action in man. Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization","volume":"31","author":"Rizza","year":"1982","journal-title":"Diabetes"},{"issue":"1 Pt 1","key":"10.1016\/j.metabol.2009.08.002_bib2","first-page":"E86","article-title":"Effects of a growth hormone pulse on total and forearm substrate fluxes in humans","volume":"258","author":"Moller","year":"1990","journal-title":"Am J Physiol"},{"key":"10.1016\/j.metabol.2009.08.002_bib3","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1210\/jc.2002-020542","article-title":"Growth hormone replacement therapy induces insulin resistance by activating the glucose-fatty acid cycle","volume":"88","author":"Bramnert","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib4","first-page":"727","article-title":"Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure","volume":"82","author":"Johannsson","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib5","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","article-title":"Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man","volume":"28","author":"Matthews","year":"1985","journal-title":"Diabetologia"},{"key":"10.1016\/j.metabol.2009.08.002_bib6","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/j.1365-2265.2004.02149.x","article-title":"Survivors of childhood acute lymphoblastic leukaemia, with radiation-induced GH deficiency, exhibit hyperleptinaemia and impaired insulin sensitivity, unaffected by 12 months of GH treatment","volume":"61","author":"Bulow","year":"2004","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"5 Suppl","key":"10.1016\/j.metabol.2009.08.002_bib7","first-page":"28","article-title":"Insulin sensitivity in growth hormone (GH)-deficient adults and effect of GH replacement therapy","volume":"22","author":"Alford","year":"1999","journal-title":"J Endocrinol Invest"},{"issue":"5","key":"10.1016\/j.metabol.2009.08.002_bib8","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1054\/ghir.2001.0240","article-title":"Commencing growth hormone replacement in adults with a fixed low dose. Effects on serum lipoproteins, glucose metabolism, body composition, and cardiovascular function","volume":"11","author":"Gillberg","year":"2001","journal-title":"Growth Horm IGF Res"},{"key":"10.1016\/j.metabol.2009.08.002_bib9","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/j.1365-2265.2005.02343.x","article-title":"Effects of 10 years of growth hormone (GH) replacement therapy in adult GH-deficient men","volume":"63","author":"Arwert","year":"2005","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.metabol.2009.08.002_bib10","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s11102-005-5065-6","article-title":"Glucose metabolism and visceral fat in GH deficient adults: two years of GH-replacement","volume":"7","author":"Spina","year":"2004","journal-title":"Pituitary"},{"key":"10.1016\/j.metabol.2009.08.002_bib11","first-page":"3762","article-title":"Effects of 7 years of growth hormone replacement therapy in hypopituitary adults","volume":"85","author":"Chrisoulidou","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib12","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1365-2265.2004.02000.x","article-title":"The effects of GH replacement in adult GH-deficient patients: changes in body composition without concomitant changes in the adipokines and insulin resistance","volume":"60","author":"Hana","year":"2004","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.metabol.2009.08.002_bib13","first-page":"3285","article-title":"Growth hormone (GH) replacement reduces total body fat and normalizes insulin sensitivity in GH-deficient adults: a report of one-year clinical experience","volume":"82","author":"Hwu","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib14","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1210\/jcem.87.5.8482","article-title":"Effects of seven years of GH-replacement therapy on insulin sensitivity in GH-deficient adults","volume":"87","author":"Svensson","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"issue":"Suppl A","key":"10.1016\/j.metabol.2009.08.002_bib15","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1016\/j.ghir.2006.03.001","article-title":"Impact of treatment with recombinant human GH and IGF-I on visceral adipose tissue and glucose homeostasis in adults","volume":"16","author":"Yuen","year":"2006","journal-title":"Growth Horm IGF Res"},{"key":"10.1016\/j.metabol.2009.08.002_bib16","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/S0140-6736(99)04055-6","article-title":"Incidence of diabetes mellitus and impaired glucose tolerance in children and adolescents receiving growth-hormone treatment","volume":"355","author":"Cutfield","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.metabol.2009.08.002_bib17","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1530\/eje.1.01817","article-title":"One year of GH replacement therapy with a fixed low-dose regimen improves body composition, bone mineral density and lipid profile of GH-deficient adults","volume":"152","author":"Boguszewski","year":"2005","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.metabol.2009.08.002_bib18","doi-asserted-by":"crossref","first-page":"5193","DOI":"10.1210\/jc.2003-030713","article-title":"Effects of growth hormone (GH) on ghrelin, leptin, and adiponectin in GH-deficient patients","volume":"88","author":"Eden Engstrom","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ghir.2003.08.002","article-title":"Glucose metabolism and visceral fat in GH deficient adults: 1 year of GH replacement","volume":"14","author":"Spina","year":"2004","journal-title":"Growth Horm IGF Res"},{"key":"10.1016\/j.metabol.2009.08.002_bib20","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.metabol.2007.08.015","article-title":"Impact of 5 years of growth hormone replacement therapy on cardiovascular risk factors in growth hormone-deficient adults","volume":"57","author":"Cenci","year":"2008","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2009.08.002_bib21","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1530\/eje.1.02283","article-title":"Sustained effects of recombinant GH replacement after 7 years of treatment in adults with GH deficiency","volume":"155","author":"van der Klaauw","year":"2006","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.metabol.2009.08.002_bib22","doi-asserted-by":"crossref","first-page":"4657","DOI":"10.1210\/jcem.86.10.7887","article-title":"A prospective study of 5 years of GH replacement therapy in GH-deficient adults: sustained effects on body composition, bone mass, and metabolic indices","volume":"86","author":"Gotherstrom","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib23","first-page":"2373","article-title":"Long-term effects of growth hormone (GH) replacement in men with childhood-onset GH deficiency","volume":"84","author":"ter Maaten","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib24","article-title":"A densitometric and morphometric analysis of the skeleton in adults with varying degrees of GH deficiency","author":"Murray","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib25","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1046\/j.1365-2265.2001.01284.x","article-title":"Effects of 6 years of growth hormone (GH) treatment on bone mineral density in GH-deficient adults","volume":"55","author":"Clanget","year":"2001","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.metabol.2009.08.002_bib26","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1530\/eje.1.02317","article-title":"Ten-year GH replacement increases bone mineral density in hypopituitary patients with adult onset GH deficiency","volume":"156","author":"Gotherstrom","year":"2007","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.metabol.2009.08.002_bib27","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1515\/CCLM.2004.112","article-title":"Reference ranges for two automated chemiluminescent assays for serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3)","volume":"42","author":"Elmlinger","year":"2004","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.metabol.2009.08.002_bib28","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1677\/joe.0.1250191","article-title":"The international reference reagent for insulin-like growth factor\u2013I","volume":"125","author":"Bristow","year":"1990","journal-title":"J Endocrinol"},{"key":"10.1016\/j.metabol.2009.08.002_bib29","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1210\/jcem.87.6.8610","article-title":"Quantification of the soluble leptin receptor in human blood by ligand-mediated immunofunctional assay","volume":"87","author":"Wu","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib30","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.2337\/diacare.22.9.1462","article-title":"Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp","volume":"22","author":"Matsuda","year":"1999","journal-title":"Diabetes Care"},{"key":"10.1016\/j.metabol.2009.08.002_bib31","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1046\/j.1365-2265.1998.00460.x","article-title":"Effects of four years' treatment with biosynthetic human growth hormone (GH) on glucose homeostasis, insulin secretion and lipid metabolism in GH-deficient adults","volume":"48","author":"al-Shoumer","year":"1998","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.metabol.2009.08.002_bib32","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/0026-0495(93)90197-V","article-title":"Effects of treatment with recombinant human growth hormone on insulin sensitivity and glucose metabolism in adults with growth hormone deficiency","volume":"42","author":"Fowelin","year":"1993","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2009.08.002_bib33","first-page":"740","article-title":"Long-term monitoring of insulin sensitivity in growth hormone-deficient adults on substitutive recombinant human growth hormone therapy","volume":"53","author":"Giavoli","year":"2004","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2009.08.002_bib34","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/j.1365-2265.2006.02507.x","article-title":"Persisting effects on fasting glucose levels and insulin sensitivity after 6 months of discontinuation of a very low-dose GH therapy in adults with severe GH deficiency","volume":"64","author":"Yuen","year":"2006","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.metabol.2009.08.002_bib35","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1365-2265.2005.02359.x","article-title":"Improvement in insulin sensitivity without concomitant changes in body composition and cardiovascular risk markers following fixed administration of a very low growth hormone (GH) dose in adults with severe GH deficiency","volume":"63","author":"Yuen","year":"2005","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.metabol.2009.08.002_bib36","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1046\/j.1365-2265.2002.01601.x","article-title":"The metabolic effects of short-term administration of physiological versus high doses of GH therapy in GH deficient adults","volume":"57","author":"Yuen","year":"2002","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.metabol.2009.08.002_bib37","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1210\/jc.2006-1487","article-title":"A 10-year, prospective study of the metabolic effects of growth hormone replacement in adults","volume":"92","author":"Gotherstrom","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib38","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1210\/jc.2002-021538","article-title":"Fat-free body mass is the most important body composition determinant of 10-yr longitudinal development of lumbar bone in adult men and women","volume":"88","author":"Bakker","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib39","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1172\/JCI110908","article-title":"Mechanisms of insulin resistance in aging","volume":"71","author":"Fink","year":"1983","journal-title":"J Clin Invest"},{"issue":"Suppl A","key":"10.1016\/j.metabol.2009.08.002_bib40","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.1016\/j.ghir.2006.03.004","article-title":"Visceral obesity, impaired glucose tolerance, metabolic syndrome, and growth hormone therapy","volume":"16","author":"Attallah","year":"2006","journal-title":"Growth Horm IGF Res"},{"key":"10.1016\/j.metabol.2009.08.002_bib41","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1530\/EJE-06-0730","article-title":"Superiority of skinfold measurements and waist over waist-to-hip ratio for determination of body fat distribution in a population-based cohort of Caucasian Dutch adults","volume":"156","author":"Ketel","year":"2007","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.metabol.2009.08.002_bib42","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1093\/oxfordjournals.aje.a008833","article-title":"Sex differences in measures of body fat and body distribution in the elderly","volume":"143","author":"Goodman-Gruen","year":"1996","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.metabol.2009.08.002_bib43","doi-asserted-by":"crossref","first-page":"111","DOI":"10.7326\/0003-4819-133-2-200007180-00010","article-title":"Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial","volume":"133","author":"Sesmilo","year":"2000","journal-title":"Ann Intern Med."},{"key":"10.1016\/j.metabol.2009.08.002_bib44","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1210\/jcem.84.8.5916","article-title":"The effects of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients","volume":"84","author":"Gibney","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib45","first-page":"1600","article-title":"Human growth hormone replacement in adult hypopituitary patients: long-term effects on body composition and lipid status\u20143-year results from the HypoCCS Database","volume":"87","author":"Attanasio","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib46","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/oby.2000.79","article-title":"Body mass index and the prevalence of hypertension and dyslipidemia","volume":"8","author":"Brown","year":"2000","journal-title":"Obes Res"},{"key":"10.1016\/j.metabol.2009.08.002_bib47","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.arcmed.2006.01.003","article-title":"Serum ghrelin and leptin levels in adult growth hormone deficiency syndrome","volume":"37","author":"Jung","year":"2006","journal-title":"Arch Med Res"},{"key":"10.1016\/j.metabol.2009.08.002_bib48","first-page":"3476","article-title":"Effect of growth hormone (GH) on serum concentrations of leptin: study in patients with acromegaly and GH deficiency","volume":"83","author":"Miyakawa","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib49","first-page":"3352","article-title":"Effects of 12 months of growth hormone (GH) treatment on calciotropic hormones, calcium homeostasis, and bone metabolism in adults with acquired GH deficiency: a double blind, randomized, placebo-controlled study","volume":"81","author":"Hansen","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib50","first-page":"2865","article-title":"Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency","volume":"81","author":"Johannsson","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib51","doi-asserted-by":"crossref","first-page":"5273","DOI":"10.1210\/jc.2003-030204","article-title":"Growth hormone (GH) dose-response in young adults with childhood-onset GH deficiency: a two-year, multicenter, multiple-dose, placebo-controlled study","volume":"88","author":"Underwood","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib52","first-page":"4104","article-title":"Growth hormone replacement therapy improves body composition and increases bone metabolism in elderly patients with pituitary disease","volume":"85","author":"Fernholm","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib53","first-page":"1288","article-title":"Serum leptin response to the acute and chronic administration of growth hormone (GH) to elderly subjects with GH deficiency","volume":"84","author":"Gill","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib54","first-page":"118","article-title":"Bone mineral status in growth hormone-deficient males with isolated and multiple pituitary deficiencies of childhood onset","volume":"74","author":"Kaufman","year":"1992","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib55","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.1210\/jcem.87.7.8593","article-title":"Body composition, IGF-I and IGFBP-3 concentrations as outcome measures in severely GH-deficient (GHD) patients after childhood GH treatment: a comparison with adult onset GHD patients","volume":"87","author":"Attanasio","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.metabol.2009.08.002_bib56","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1007\/s11695-008-9548-1","article-title":"The bone-adipose axis in obesity and weight loss","volume":"18","author":"Gomez-Ambrosi","year":"2008","journal-title":"Obes Surg"},{"key":"10.1016\/j.metabol.2009.08.002_bib57","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1210\/jc.2006-2097","article-title":"Serum adiponectin and bone mineral density in women","volume":"92","author":"Richards","year":"2007","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049509003266?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049509003266?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T03:40:48Z","timestamp":1758426048000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026049509003266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":57,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0026049509003266"],"URL":"https:\/\/doi.org\/10.1016\/j.metabol.2009.08.002","relation":{},"ISSN":["0026-0495"],"issn-type":[{"type":"print","value":"0026-0495"}],"subject":[],"published":{"date-parts":[[2010,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of glucose and lipid metabolism and bone mineralization in patients with growth hormone deficiency with and without long-term growth hormone replacement","name":"articletitle","label":"Article Title"},{"value":"Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.metabol.2009.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown copyright \u00a9 2010 Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}