{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:53:28Z","timestamp":1762505608871,"version":"3.44.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","metabolismjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Metabolism"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1016\/j.metabol.2010.04.015","type":"journal-article","created":{"date-parts":[[2010,5,24]],"date-time":"2010-05-24T04:29:03Z","timestamp":1274675343000},"page":"491-498","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Adeno-associated virus serotypes 7 and 8 outperform serotype 9 in expressing atheroprotective human apoE3 from mouse skeletal muscle"],"prefix":"10.1016","volume":"60","author":[{"given":"Vanessa C.","family":"Evans","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian R.","family":"Graham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takis","family":"Athanasopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah J.","family":"Galley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan Paul","family":"Simons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Dickson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James S.","family":"Owen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.metabol.2010.04.015_bb0005","first-page":"275","article-title":"ApoE gene therapy to treat hyperlipidemia and atherosclerosis","volume":"8","author":"Harris","year":"2006","journal-title":"Curr Opin Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0010","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1161\/01.ATV.0000128849.12617.f4","article-title":"Atherosclerosis in the apolipoprotein-E\u2013deficient mouse: a decade of progress","volume":"24","author":"Meir","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0015","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1161\/01.ATV.15.4.479","article-title":"Phenotypic correction of hypercholesterolemia in apoE-deficient mice by adenovirus-mediated in vivo gene transfer","volume":"15","author":"Stevenson","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0020","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/hmg\/11.1.43","article-title":"Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generation [E1(\u2212), E3(\u2212), polymerase(\u2212)] adenovirus vector expressing human apoE","volume":"11","author":"Harris","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.metabol.2010.04.015_bb0025","doi-asserted-by":"crossref","first-page":"13282","DOI":"10.1073\/pnas.241506298","article-title":"Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector","volume":"98","author":"Kim","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.metabol.2010.04.015_bb0030","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1038\/mt.2008.37","article-title":"The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver","volume":"16","author":"McCaffrey","year":"2008","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0035","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/gt.2009.148","article-title":"Progress and prospects: immune responses to viral vectors","volume":"17","author":"Nayak","year":"2010","journal-title":"Gene Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0040","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.ymthe.2006.05.009","article-title":"Adeno-associated virus serotypes: vector toolkit for human gene therapy","volume":"14","author":"Wu","year":"2006","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0045","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00439-006-0165-6","article-title":"Treatment of human disease by adeno-associated viral gene transfer","volume":"119","author":"Warrington","year":"2006","journal-title":"Hum Genet"},{"key":"10.1016\/j.metabol.2010.04.015_bb0050","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/sj.gt.3301615","article-title":"Inhibition of atherosclerosis in apolipoprotein-E\u2013deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E","volume":"9","author":"Harris","year":"2002","journal-title":"Gene Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0055","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1006\/mthe.2000.0219","article-title":"Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors","volume":"2","author":"Chao","year":"2000","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0060","doi-asserted-by":"crossref","first-page":"11854","DOI":"10.1073\/pnas.182412299","article-title":"Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy","volume":"99","author":"Gao","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.metabol.2010.04.015_bb0065","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1002\/jgm.686","article-title":"Gene transfer into skeletal muscle using novel AAV serotypes","volume":"7","author":"Louboutin","year":"2005","journal-title":"J Gene Med"},{"key":"10.1016\/j.metabol.2010.04.015_bb0070","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.virol.2004.10.012","article-title":"Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid protein","volume":"330","author":"Mori","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.metabol.2010.04.015_bb0075","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1128\/JVI.02012-07","article-title":"Adeno-associated virus type 12 (AAV12): a novel AAV serotype with sialic acid- and heparan sulfate proteoglycan-independent transduction activity","volume":"82","author":"Schmidt","year":"2008","journal-title":"J Virol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0080","doi-asserted-by":"crossref","first-page":"7875","DOI":"10.1128\/JVI.00649-08","article-title":"Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle","volume":"82","author":"Penaud-Budloo","year":"2008","journal-title":"J Virol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0085","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1038\/mt.2008.133","article-title":"Correction of multiple striated muscles in murine Pompe disease through adeno-associated virus-mediated gene therapy","volume":"16","author":"Sun","year":"2008","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0090","doi-asserted-by":"crossref","first-page":"17158","DOI":"10.1073\/pnas.0909520106","article-title":"Distinct immune responses to transgene products from rAAV1 and rAAV8 vectors","volume":"106","author":"Lu","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.metabol.2010.04.015_bb0095","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1038\/mt.2008.76","article-title":"Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection","volume":"16","author":"Zincarelli","year":"2008","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0100","doi-asserted-by":"crossref","first-page":"6381","DOI":"10.1128\/JVI.78.12.6381-6388.2004","article-title":"Clades of adeno-associated viruses are widely disseminated in human tissues","volume":"78","author":"Gao","year":"2004","journal-title":"J Virol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0105","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ymthe.2006.03.014","article-title":"Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8","volume":"14","author":"Inagaki","year":"2006","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0110","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1161\/01.RES.0000237661.18885.f6","article-title":"Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo","volume":"99","author":"Pacak","year":"2006","journal-title":"Circ Res"},{"key":"10.1016\/j.metabol.2010.04.015_bb0115","doi-asserted-by":"crossref","DOI":"10.1089\/hum.2009.182","article-title":"Prevalence of serum IgG and neutralizing factors against adeno-associated virus types 1, 2, 5, 6, 8 and 9 in the healthy population: implications for gene therapy using AAV vectors","author":"Boutin","year":"2010","journal-title":"Hum Gene Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0120","doi-asserted-by":"crossref","first-page":"12993","DOI":"10.1073\/pnas.0601433103","article-title":"Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered","volume":"103","author":"Limberis","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.metabol.2010.04.015_bb0125","first-page":"672","article-title":"Development of multiple cloning site cis-vectors for recombinant adeno-associated virus production","volume":"33","author":"Yue","year":"2002","journal-title":"Biotechniques"},{"key":"10.1016\/j.metabol.2010.04.015_bb0130","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/sj.gt.3300938","article-title":"Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield","volume":"6","author":"Zolotukhin","year":"1999","journal-title":"Gene Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0135","unstructured":"Snyder RO, Xiao X, Samulski RJ. Production of recombinant adeno-associated viral vectors. Current protocols in human genetics (John Wiley & Sons) 1996; 12.1.11-15."},{"key":"10.1016\/j.metabol.2010.04.015_bb0140","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0021-9150(00)00515-3","article-title":"Atherosclerotic plaque rupture in the apolipoprotein E knockout mouse","volume":"154","author":"Johnson","year":"2001","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.metabol.2010.04.015_bb0145","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1161\/01.CIR.0000158435.98035.8D","article-title":"Plaque rupture after short periods of fat feeding in the apolipoprotein E\u2013knockout mouse: model characterization and effects of pravastatin treatment","volume":"111","author":"Johnson","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.metabol.2010.04.015_bb0150","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1128\/JVI.78.6.3110-3122.2004","article-title":"Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors","volume":"78","author":"Thomas","year":"2004","journal-title":"J Virol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0155","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/sj.mt.6300053","article-title":"A two-hybrid screen identifies cathepsins B and L as uncoating factors for adeno-associated virus 2 and 8","volume":"15","author":"Akache","year":"2007","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0160","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0092-8674(92)90362-G","article-title":"Severe hypercholesterolemia and atherosclerosis in apolipoprotein E\u2013deficient mice created by homologous recombination in ES cells","volume":"71","author":"Plump","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.metabol.2010.04.015_bb0165","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1172\/JCI117460","article-title":"Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption","volume":"94","author":"Zhang","year":"1994","journal-title":"J Clin Invest"},{"key":"10.1016\/j.metabol.2010.04.015_bb0170","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0021-9150(94)05419-J","article-title":"Atypical xanthomatosis in apolipoprotein E\u2013deficient mice after cholesterol feeding","volume":"112","author":"van Ree","year":"1995","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.metabol.2010.04.015_bb0175","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1476-511X-8-30","article-title":"Protonated nanostructured aluminosilicate (NSAS) reduces plasma cholesterol concentrations and atherosclerotic lesions in apolipoprotein E deficient mice fed a high cholesterol and high fat diet","volume":"8","author":"Sivak","year":"2009","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.metabol.2010.04.015_bb0180","doi-asserted-by":"crossref","first-page":"52559","DOI":"10.1074\/jbc.M310892200","article-title":"Overexpression of SR-BI by adenoviral vector reverses the fibrate induced hypercholesterolemia of apolipoprotein E\u2013deficient mice","volume":"278","author":"Fu","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.metabol.2010.04.015_bb0185","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1194\/jlr.M700355-JLR200","article-title":"Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo","volume":"9","author":"Van Eck","year":"2008","journal-title":"J Lipid Res"},{"key":"10.1016\/j.metabol.2010.04.015_bb0190","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1016\/S0022-2275(20)34932-4","article-title":"Hepatic uptake of chylomicron remnants","volume":"38","author":"Cooper","year":"1997","journal-title":"J Lipid Res"},{"key":"10.1016\/j.metabol.2010.04.015_bb0195","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1161\/01.ATV.20.8.1939","article-title":"Low levels of extrahepatic nonmacrophage ApoE inhibit atherosclerosis without correcting hypercholesterolemia in ApoE-deficient mice","volume":"20","author":"Thorngate","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0200","doi-asserted-by":"crossref","first-page":"17972","DOI":"10.1074\/jbc.272.29.17972","article-title":"Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis","volume":"272","author":"Sullivan","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/j.metabol.2010.04.015_bb0205","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1161\/01.ATV.0000014587.66321.B4","article-title":"Characteristics of intact and ruptured atherosclerotic plaques in brachiocephalic arteries of apolipoprotein E knockout mice","volume":"22","author":"Williams","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0210","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1161\/01.ATV.20.5.1262","article-title":"Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions","volume":"20","author":"Virmani","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0215","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1038\/sj.gt.3300890","article-title":"A novel endothelial cell-based gene therapy platform for the in vivo delivery of apolipoprotein E","volume":"6","author":"Cioffi","year":"1999","journal-title":"Gene Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0220","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1093\/hmg\/9.17.2545","article-title":"Intramuscular injection of a plasmid vector expressing human apolipoprotein E limits progression of xanthoma and aortic atheroma in apoE-deficient mice","volume":"9","author":"Athanasopoulos","year":"2000","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.metabol.2010.04.015_bb0225","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1161\/01.ATV.0000134297.61979.3c","article-title":"Subphysiologic apolipoprotein E (ApoE) plasma levels inhibit neointimal formation after arterial injury in ApoE-deficient mice","volume":"24","author":"Wientgen","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0230","doi-asserted-by":"crossref","first-page":"46011","DOI":"10.1074\/jbc.M104812200","article-title":"Cell-derived apolipoprotein E (ApoE) particles inhibit vascular cell adhesion molecule\u20131 (VCAM-1) expression in human endothelial cells","volume":"276","author":"Stannard","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.metabol.2010.04.015_bb0235","first-page":"3","article-title":"Altered gene expression in early atherosclerosis is blocked by low level apolipoprotein E","volume":"e2503","author":"Ma","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.metabol.2010.04.015_bb0240","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1161\/ATVBAHA.108.176685","article-title":"Genetic regulation of atherosclerotic plaque size and morphology in the innominate artery of hyperlipidemic mice","volume":"29","author":"Bennett","year":"2009","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.metabol.2010.04.015_bb0245","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1182\/blood-2002-09-2889","article-title":"Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway","volume":"122","author":"Davidoff","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.metabol.2010.04.015_bb0250","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1038\/mt.2009.139","article-title":"Sexually dimorphic patterns of episomal rAAV genome persistence in the adult mouse liver and correlation with hepatocellular proliferation","volume":"17","author":"Dane","year":"2009","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0255","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1038\/gt.2008.54","article-title":"Immunity to adeno-associated virus vectors in animals and humans: a continued challenge","volume":"15","author":"Zaiss","year":"2008","journal-title":"Gene Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0260","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/sj.mt.6300027","article-title":"Design of tissue-specific regulatory cassettes for high-level rAAV-mediated expression in skeletal and cardiac muscle","volume":"15","author":"Salva","year":"2007","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0265","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1038\/mt.2008.100","article-title":"Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles","volume":"16","author":"Li","year":"2008","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0270","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/sj.mt.6300355","article-title":"Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose","volume":"16","author":"Wu","year":"2008","journal-title":"Mol Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0275","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1038\/sj.gt.3302134","article-title":"Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo","volume":"10","author":"McCarty","year":"2003","journal-title":"Gene Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0280","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1038\/sj.gt.3302133","article-title":"Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo","volume":"10","author":"Wang","year":"2003","journal-title":"Gene Ther"},{"key":"10.1016\/j.metabol.2010.04.015_bb0285","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.atherosclerosis.2008.08.043","article-title":"Preliminary evaluation of a self-complementary AAV2\/8 vector for hepatic gene transfer of human apoE3 to inhibit atherosclerotic lesion development in apoE-deficient mice","volume":"204","author":"Osman","year":"2009","journal-title":"Atherosclerosis"}],"container-title":["Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049510001411?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049510001411?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T03:50:10Z","timestamp":1758426610000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026049510001411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["S0026049510001411"],"URL":"https:\/\/doi.org\/10.1016\/j.metabol.2010.04.015","relation":{},"ISSN":["0026-0495"],"issn-type":[{"type":"print","value":"0026-0495"}],"subject":[],"published":{"date-parts":[[2011,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adeno-associated virus serotypes 7 and 8 outperform serotype 9 in expressing atheroprotective human apoE3 from mouse skeletal muscle","name":"articletitle","label":"Article Title"},{"value":"Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.metabol.2010.04.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}