{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:51:15Z","timestamp":1792608675890,"version":"4.5.0"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81471054"],"award-info":[{"award-number":["81471054"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81660150"],"award-info":[{"award-number":["81660150"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","metabolismjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Metabolism"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.metabol.2020.154378","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T13:24:43Z","timestamp":1601299483000},"page":"154378","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":380,"special_numbering":"C","title":["Obesity in patients with COVID-19: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"113","author":[{"given":"Yi","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Mei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Sui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Lu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.metabol.2020.154378_bb0005","author":"World Health Organization"},{"key":"10.1016\/j.metabol.2020.154378_bb0010","author":"World Health Organization"},{"key":"10.1016\/j.metabol.2020.154378_bb0015","article-title":"Severe Covid-19[published online ahead of print, 2020 May 15]","author":"Berlin","year":"2020","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.metabol.2020.154378_bb0020","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S1470-2045(20)30096-6","article-title":"Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China","volume":"21","author":"Liang","year":"2020","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.metabol.2020.154378_bb0025","author":"World Health Organization"},{"key":"10.1016\/j.metabol.2020.154378_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/S1473-3099(20)30371-6","article-title":"Risk factors for SARS-CoV-2 among patients in the Oxford Royal College of general practitioners research and surveillance Centre primary care network: a cross-sectional study[published online ahead of print, 2020 May 15]","author":"de Lusignan","year":"2020","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.metabol.2020.154378_bb0035","article-title":"Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City","author":"Petrilli","year":"2020","journal-title":"Preprint at medRxiv"},{"issue":"7","key":"10.1016\/j.metabol.2020.154378_bb0040","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1002\/oby.22831","article-title":"High prevalence of obesity in severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation","volume":"28","author":"Simonnet","year":"2020","journal-title":"Obesity (Silver Spring)"},{"issue":"7","key":"10.1016\/j.metabol.2020.154378_bb0045","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.2337\/dc20-0576","article-title":"Obesity and COVID-19 severity in a designated Hospital in Shenzhen","volume":"43","author":"Cai","year":"2020","journal-title":"China. Diabetes Care"},{"issue":"15","key":"10.1016\/j.metabol.2020.154378_bb0050","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/cid\/ciaa415","article-title":"Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission","volume":"71","author":"Lighter","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.metabol.2020.154378_bb0055","doi-asserted-by":"crossref","first-page":"104931","DOI":"10.1016\/j.phrs.2020.104931","article-title":"30-day mortality in patients hospitalized with COVID-19 during the first wave of the Italian epidemic: a prospective cohort study","volume":"158","author":"Giacomelli","year":"2020","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.metabol.2020.154378_bb0060","first-page":"154262","article-title":"Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality, in a cohort of patients with COVID-19 in the Bronx","volume":"108","author":"Palaiodimos","year":"2020","journal-title":"New York Metabolism"},{"issue":"10239","key":"10.1016\/j.metabol.2020.154378_bb0065","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1016\/S0140-6736(20)31189-2","article-title":"Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study","volume":"395","author":"Cummings","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.metabol.2020.154378_bb0070","doi-asserted-by":"crossref","first-page":"154319","DOI":"10.1016\/j.metabol.2020.154319","article-title":"Visceral fat shows the strongest association with the need of intensive Care in Patients with COVID-19[published online ahead of print, 2020 Jul 23]","author":"Watanabe","year":"2020","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2020.154378_bb0075","article-title":"Visceral Adiposity and High Intramuscular Fat Deposition Independently Predict Critical Illness in Patients with Sars-COV-2 [published online ahead of print, 2020 Jul 17]","author":"Yang","year":"2020","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.metabol.2020.154378_bb0080","doi-asserted-by":"crossref","first-page":"k4817","DOI":"10.1136\/bmj.k4817","article-title":"When continuous outcomes are measured using different scales: guide for meta-analysis and interpretation","volume":"364","author":"Murad","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.metabol.2020.154378_bb0085","article-title":"A cohort of patients with COVID-19 in a major teaching hospital in Europe","author":"Borobia","year":"2020","journal-title":"Preprint at medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0090","doi-asserted-by":"crossref","unstructured":"Kim L, Garg S, O'Halloran A, Whitaker M, Pham H, Anderson EJ, et al. Interim Analysis of Risk Factors for Severe Outcomes among a Cohort of Hospitalized Adults Identified through the U.S. Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET). Preprint at medRxiv 2020. https:\/\/doi.org\/10.1101\/2020.05.18.20103390.","DOI":"10.1093\/cid\/ciaa1012"},{"key":"10.1016\/j.metabol.2020.154378_bb0095","article-title":"Pre-existing traits associated with Covid-19 illness severity","author":"Ebinger","year":"2020","journal-title":"Preprint at medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0100","article-title":"Early experience with COVD-19 patients at tertiary care teaching hospital in southwestern United States","author":"Shekhar","year":"2020","journal-title":"Preprint at medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0105","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jpeds.2020.05.006","article-title":"Clinical characteristics and outcomes of hospitalized and critically ill children and adolescents with coronavirus disease 2019 (COVID-19) at a tertiary care medical center in New York City","volume":"223","author":"Chao","year":"2020","journal-title":"J Pediatr"},{"key":"10.1016\/j.metabol.2020.154378_bb0110","article-title":"Lung disease severity, coronary artery calcium, coronary inflammation and mortality in coronavirus disease 2019","author":"Gaibazzi","year":"2020","journal-title":"Preprint at medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0115","article-title":"Characteristics and outcomes of a cohort of SARS-CoV-2 patients in the Province of Reggio Emilia, Italy","author":"Giorgi Rossi","year":"2020","journal-title":"Preprint at medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0120","article-title":"Early estimation of the risk factors for hospitalisation and mortality by COVID-19 in Mexico","author":"Carrillo-Vega","year":"2020","journal-title":"Preprint at medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0125","doi-asserted-by":"crossref","unstructured":"Battisti S, Pedone C, Napoli N, Russo E, Agnoletti V, Nigra SG, et al. Computed tomography highlights increased visceral adiposity associated with critical illness in COVID-19 [published online ahead of print, 2020 Aug 4]. Diabetes Care 2020: dc201333. https:\/\/doi.org\/10.2337\/dc20-1333.","DOI":"10.2337\/dc20-1333"},{"key":"10.1016\/j.metabol.2020.154378_bb0130","first-page":"1","article-title":"Visceral adipose tissue in patients with COVID-19: risk stratification for severity [published online ahead of print, 2020 Aug 3]","author":"Chandarana","year":"2020","journal-title":"Abdom Radiol (NY)"},{"issue":"4","key":"10.1016\/j.metabol.2020.154378_bb0135","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.dsx.2020.05.020","article-title":"Obesity as a predictor for a poor prognosis of COVID-19: a systematic review","volume":"14","author":"Tamara","year":"2020","journal-title":"Diabetes Metab Syndr"},{"key":"10.1016\/j.metabol.2020.154378_bb0140","first-page":"1","article-title":"Higher body mass index is an important risk factor in COVID-19 patients: a systematic review and meta-analysis [published online ahead of print, 2020 Jul 24]","author":"Malik","year":"2020","journal-title":"Environ Sci Pollut Res Int"},{"key":"10.1016\/j.metabol.2020.154378_bb0145","article-title":"Coronavirus (SARS-CoV-2) and the risk of obesity for critically illness and ICU admitted: meta-analysis of the pidemiological evidence [published online ahead of print, 2020 Aug 3]","author":"Sales-Peres","year":"2020","journal-title":"Obes Res Clin Pract"},{"key":"10.1016\/j.metabol.2020.154378_bb0150","article-title":"Obesity is a risk factor for developing critical condition in COVID-19 patients: a systematic review and meta-analysis [published online ahead of print, 2020 Jul 19]","author":"Foldi","year":"2020","journal-title":"Obes Rev"},{"issue":"20","key":"10.1016\/j.metabol.2020.154378_bb0155","first-page":"30097","article-title":"Body mass index and outcome in patients with COVID-19: a dose-response meta-analysis [published online ahead of print, 2020 Jul 29]","volume":"S1262-3636","author":"Pranata","year":"2020","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.metabol.2020.154378_bb0160","doi-asserted-by":"crossref","unstructured":"Hussain A, Mahawar K, Xia Z, Yang W, El-Hasani S. Obesity and mortality of COVID-19. Meta-analysis [published online ahead of print, 2020 Jul 9]. Obes Res Clin Pract 2020; 14(4): 295\u2013300. https:\/\/doi.org\/10.1016\/j.orcp.2020.07.002.","DOI":"10.1016\/j.orcp.2020.07.002"},{"key":"10.1016\/j.metabol.2020.154378_bb0165","article-title":"Obesity aggravates COVID-19: a systematic review and meta-analysis [published online ahead of print, 2020 Jun 30]","author":"Yang","year":"2020","journal-title":"J Med Virol"},{"key":"10.1016\/j.metabol.2020.154378_bb0170","article-title":"Association of BMI and obesity with composite poor outcome in COVID-19 adult patients: a systematic review and meta-analysis","author":"Soeroto","year":"2020","journal-title":"medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0175","doi-asserted-by":"crossref","unstructured":"Pettit NN, MacKenzie EL, Ridgway J, Pursell K, Ash D, Patel B, et al. Obesity is associated with increased risk for mortality among hospitalized patients with COVID-19 [published online ahead of print, 2020 Jun 26]. Obesity (Silver Spring) 2020. https:\/\/doi.org\/10.1002\/oby.22941.","DOI":"10.1002\/oby.22941"},{"key":"10.1016\/j.metabol.2020.154378_bb0180","author":"Prevention CfDCa"},{"key":"10.1016\/j.metabol.2020.154378_bb0185","author":"World Health Organization"},{"issue":"2","key":"10.1016\/j.metabol.2020.154378_bb0190","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1056\/NEJMc2007617","article-title":"Coronavirus infection in pediatric emergency departments research G. children with Covid-19 in pediatric emergency departments in Italy","volume":"383","author":"Parri","year":"2020","journal-title":"N Engl J Med"},{"issue":"10236","key":"10.1016\/j.metabol.2020.154378_bb0195","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/S0140-6736(20)31024-2","article-title":"Obesity could shift severe COVID-19 disease to younger ages","volume":"395","author":"Kass","year":"2020","journal-title":"The Lancet"},{"key":"10.1016\/j.metabol.2020.154378_bb0200","article-title":"Severe obesity as an independent risk factor for COVID-19 mortality in hospitalized patients younger than 50 [published online ahead of print, 2020 May 23]","author":"Klang","year":"2020","journal-title":"Obesity (Silver Spring)"},{"issue":"5","key":"10.1016\/j.metabol.2020.154378_bb0205","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.dsx.2020.06.060","article-title":"BMI and future risk for COVID-19 infection and death across sex, age and ethnicity: preliminary findings from UK biobank","volume":"14","author":"Sattar","year":"2020","journal-title":"Diabetes Metab Syndr"},{"key":"10.1016\/j.metabol.2020.154378_bb0210","doi-asserted-by":"crossref","first-page":"343","DOI":"10.3389\/fcimb.2018.00343","article-title":"Back to the future: lessons learned from the 1918 influenza pandemic","volume":"8","author":"Short","year":"2018","journal-title":"Front Cell Infect Microbiol"},{"issue":"6","key":"10.1016\/j.metabol.2020.154378_bb0215","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/s00592-020-01522-8","article-title":"Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic","volume":"57","author":"Luzi","year":"2020","journal-title":"Acta Diabetol"},{"issue":"8","key":"10.1016\/j.metabol.2020.154378_bb0220","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/j.1467-789X.2011.00864.x","article-title":"Obesity is associated with higher risk of intensive care unit admission and death in influenza A (H1N1) patients: a systematic review and meta-analysis","volume":"12","author":"Fezeu","year":"2011","journal-title":"Obes Rev"},{"issue":"7","key":"10.1016\/j.metabol.2020.154378_bb0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001053","article-title":"Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis","volume":"8","author":"Van Kerkhove","year":"2011","journal-title":"PLoS Med"},{"issue":"7","key":"10.1016\/j.metabol.2020.154378_bb0230","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/s41574-020-0364-6","article-title":"Obesity and impaired metabolic health in patients with COVID-19","volume":"16","author":"Stefan","year":"2020","journal-title":"Nat Rev Endocrinol"},{"issue":"1","key":"10.1016\/j.metabol.2020.154378_bb0235","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1440-1843.2011.02096.x","article-title":"Impact of obesity on respiratory function","volume":"17","author":"Littleton","year":"2012","journal-title":"Respirology"},{"issue":"20","key":"10.1016\/j.metabol.2020.154378_bb0240","first-page":"30288","article-title":"Dyspnea rather than fever is a risk factor for predicting mortality in patients with COVID-19 [published online ahead of print, 2020 May 15]","volume":"S0163-4453","author":"Shi","year":"2020","journal-title":"J Infect"},{"key":"10.1016\/j.metabol.2020.154378_bb0245","doi-asserted-by":"crossref","first-page":"154249","DOI":"10.1016\/j.metabol.2020.154249","article-title":"Letter to the editor: obesity hypoventilation syndrome and severe COVID-19","volume":"108","author":"Huang","year":"2020","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2020.154378_bb0250","doi-asserted-by":"crossref","first-page":"154251","DOI":"10.1016\/j.metabol.2020.154251","article-title":"Commentary: obesity: the \u201cAchilles heel\u201d for COVID-19?","volume":"108","author":"Muscogiuri","year":"2020","journal-title":"Metabolism"},{"key":"10.1016\/j.metabol.2020.154378_bb0255","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ijid.2020.07.029","article-title":"Comorbidities and the risk of severe or fatal outcomes associated with coronavirus disease 2019: a systematic review and meta-analysis [published online ahead of print, 2020 Jul 25]","volume":"99","author":"Zhou","year":"2020","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.metabol.2020.154378_bb0260","doi-asserted-by":"crossref","first-page":"154256","DOI":"10.1016\/j.metabol.2020.154256","article-title":"Letter to the editor: obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease","volume":"108","author":"Hussain","year":"2020","journal-title":"Metabolism"},{"issue":"6","key":"10.1016\/j.metabol.2020.154378_bb0265","doi-asserted-by":"crossref","DOI":"10.1111\/obr.13034","article-title":"Risk of COVID-19 for patients with obesity","volume":"21","author":"Kassir","year":"2020","journal-title":"Obes Rev"},{"issue":"9","key":"10.1016\/j.metabol.2020.154378_bb0270","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1093\/infdis\/jiy370","article-title":"Obesity increases the duration of influenza a virus shedding in adults","volume":"218","author":"Maier","year":"2018","journal-title":"J Infect Dis"},{"issue":"5","key":"10.1016\/j.metabol.2020.154378_bb0275","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1073\/pnas.1716561115","article-title":"Bueno de Mesquita PJ, Albert B, Liu F, et al. Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community","volume":"115","author":"Yan","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.metabol.2020.154378_bb0280","doi-asserted-by":"crossref","first-page":"E105","DOI":"10.1152\/ajpendo.00198.2020","article-title":"Obesity and COVID-19: immune and metabolic derangement as a possible link to adverse clinical outcomes","volume":"319","author":"Korakas","year":"2020","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.metabol.2020.154378_bb0285","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1161\/CIRCULATIONAHA.120.047659","article-title":"Obesity is a risk factor for severe COVID-19 infection: multiple potential mechanisms","volume":"142","author":"Sattar","year":"2020","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.metabol.2020.154378_bb0290","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1038\/s41366-020-0597-4","article-title":"COVID-19 and the role of chronic inflammation in patients with obesity","volume":"44","author":"Chiappetta","year":"2020","journal-title":"Int J Obes (Lond)"},{"key":"10.1016\/j.metabol.2020.154378_bb0295","doi-asserted-by":"crossref","first-page":"e3325","DOI":"10.1002\/dmrr.3325","article-title":"Obesity and SARS-CoV-2: a population to safeguard","author":"Watanabe","year":"2020","journal-title":"Diabetes Metab Res Rev"},{"issue":"3","key":"10.1016\/j.metabol.2020.154378_bb0300","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1073\/pnas.1809046116","article-title":"Nutrition, the visceral immune system, and the evolutionary origins of pathogenic obesity","volume":"116","author":"West-Eberhard","year":"2019","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"10.1016\/j.metabol.2020.154378_bb0305","doi-asserted-by":"crossref","first-page":"e179","DOI":"10.2337\/dc16-1025","article-title":"Abdominal obesity is more closely associated with diabetic kidney disease than general obesity","volume":"39","author":"Hu","year":"2016","journal-title":"Diabetes Care"},{"issue":"4","key":"10.1016\/j.metabol.2020.154378_bb0310","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1053\/meta.2001.21693","article-title":"deJonge L, de la Bretonne J, et al. Contributions of total body fat, abdominal subcutaneous adipose tissue compartments, and visceral adipose tissue to the metabolic complications of obesity","volume":"50","author":"Smith","year":"2001","journal-title":"Metabolism"},{"issue":"17","key":"10.1016\/j.metabol.2020.154378_bb0315","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1161\/CIRCULATIONAHA.114.015000","article-title":"Association between visceral and subcutaneous adipose depots and incident cardiovascular disease risk factors","volume":"132","author":"Abraham","year":"2015","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.metabol.2020.154378_bb0320","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S2213-8587(19)30084-1","article-title":"Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement","volume":"7","author":"Neeland","year":"2019","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.metabol.2020.154378_bb0325","doi-asserted-by":"crossref","first-page":"154317","DOI":"10.1016\/j.metabol.2020.154317","article-title":"The role of visceral adiposity in the severity of COVID-19: highlights from a unicenter cross-sectional pilot study in Germany","volume":"110","author":"Petersen","year":"2020","journal-title":"Metabolism"},{"issue":"12","key":"10.1016\/j.metabol.2020.154378_bb0330","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1038\/sj.ijo.0803683","article-title":"A dose-response relation between aerobic exercise and visceral fat reduction: systematic review of clinical trials","volume":"31","author":"Ohkawara","year":"2007","journal-title":"Int J Obes (Lond)"},{"key":"10.1016\/j.metabol.2020.154378_bb0335","article-title":"Obesity & genetic predisposition with COVID-19","volume":"154345","author":"Zhu","year":"2020","journal-title":"Metabolism"},{"issue":"7","key":"10.1016\/j.metabol.2020.154378_bb0340","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1002\/oby.22859","article-title":"Association of obesity with disease severity among patients with COVID-19","volume":"28","author":"Kalligeros","year":"2020","journal-title":"Obesity"},{"issue":"24","key":"10.1016\/j.metabol.2020.154378_bb0345","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1056\/NEJMc2010419","article-title":"Clinical characteristics of Covid-19 in New York City","volume":"382","author":"Goyal","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.metabol.2020.154378_bb0350","series-title":"Preprint at medRxiv","article-title":"Characterization and clinical course of 1000 Patients with COVID-19 in New York: retrospective case series","author":"Argenziano","year":"2020"},{"key":"10.1016\/j.metabol.2020.154378_bb0355","article-title":"COVID-19: impact of obesity and diabetes in disease severity","author":"Al-Sabah","year":"2020","journal-title":"Preprint at medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0360","doi-asserted-by":"crossref","first-page":"m1966","DOI":"10.1136\/bmj.m1966","article-title":"Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study","volume":"369","author":"Petrilli","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.metabol.2020.154378_bb0365","article-title":"Derivation of a score to predict admission to intensive care unit in patients with COVID-19: the ABC-GOALS score","author":"Mejia-Vilet","year":"2020","journal-title":"Preprint at medRxiv"},{"issue":"1","key":"10.1016\/j.metabol.2020.154378_bb0370","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1177\/0194599820929640","article-title":"Factors associated with intubation and prolonged intubation in hospitalized patients with COVID-19","volume":"163","author":"Hur","year":"2020","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.metabol.2020.154378_bb0375","series-title":"Preprint at medRxiv","article-title":"Determinants of severity in cancer patients with COVID-19 illness","author":"Robilotti","year":"2020"},{"key":"10.1016\/j.metabol.2020.154378_bb0380","series-title":"Preprint at medRxiv","article-title":"Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: an observational retrospective study","author":"Regina","year":"2020"},{"key":"10.1016\/j.metabol.2020.154378_bb0385","series-title":"Preprint at medRxiv","article-title":"Sociodemographic predictors of outcomes in COVID-19: examining the impact of ethnic disparities in Northern Nevada","author":"Antwi-Amoabeng","year":"2020"},{"key":"10.1016\/j.metabol.2020.154378_bb0390","article-title":"Survival in adult inpatients with COVID-19","author":"Murillo-Zamora","year":"2020","journal-title":"Preprint at medRxiv"},{"key":"10.1016\/j.metabol.2020.154378_bb0395","doi-asserted-by":"crossref","first-page":"108331","DOI":"10.1016\/j.diabres.2020.108331","article-title":"Demographic and clinical features of critically ill patients with COVID-19 in Greece: the burden of diabetes and obesity [published online ahead of print, 2020 Jul 17]","volume":"166","author":"Halvatsiotis","year":"2020","journal-title":"Diabetes Res Clin Pract"},{"issue":"4","key":"10.1016\/j.metabol.2020.154378_bb0400","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1530\/EJE-20-0541","article-title":"How important is obesity as a risk factor for respiratory failure, intensive care admission and death in hospitalised COVID-19 patients? Results from a single Italian centre","volume":"183","author":"Rottoli","year":"2020","journal-title":"Eur J Endocrinol"},{"issue":"4","key":"10.1016\/j.metabol.2020.154378_bb0405","doi-asserted-by":"crossref","first-page":"752","DOI":"10.5811\/westjem.2020.5.47972","article-title":"In young adults with COVID-19, obesity is associated with adverse outcomeS","volume":"21","author":"Steinberg","year":"2020","journal-title":"West J Emerg Med"},{"key":"10.1016\/j.metabol.2020.154378_bb0410","first-page":"1","article-title":"The impact of obesity on COVID-19 complications: a retrospective cohort study","author":"Nakeshbandi","year":"2020","journal-title":"Int J Obes (Lond)"}],"container-title":["Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049520302420?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026049520302420?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:15:04Z","timestamp":1777425304000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026049520302420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":82,"alternative-id":["S0026049520302420"],"URL":"https:\/\/doi.org\/10.1016\/j.metabol.2020.154378","relation":{},"ISSN":["0026-0495"],"issn-type":[{"value":"0026-0495","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Obesity in patients with COVID-19: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.metabol.2020.154378","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"154378"}}