{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T21:02:39Z","timestamp":1792616559180,"version":"4.5.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T00:00:00Z","timestamp":1570492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003406","name":"Tekes","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003406","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Metabolism Open"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.metop.2019.100019","type":"journal-article","created":{"date-parts":[[2019,10,10]],"date-time":"2019-10-10T19:09:02Z","timestamp":1570734542000},"page":"100019","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Beneficial effects of running and milk protein supplements on Sirtuins and risk factors of metabolic disorders in rats with low aerobic capacity"],"prefix":"10.1016","volume":"4","author":[{"given":"S.","family":"Lensu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.P.","family":"Pekkala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"M\u00e4kinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Karstunen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.T.","family":"Turpeinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.J.","family":"Hulmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.M.","family":"Silvennoinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.M.","family":"Kujala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Karvinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.G.","family":"Koch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.L.","family":"Britton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Kainulainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.metop.2019.100019_bib1","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1017\/thg.2015.23","article-title":"Health-related findings among twin pairs discordant for leisure-time physical activity for 32 Years: the TWINACTIVE study synopsis","volume":"18","author":"Leskinen","year":"2015","journal-title":"Twin Res Hum Genet"},{"key":"10.1016\/j.metop.2019.100019_bib2","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/obr.12005","article-title":"The effects of whey protein on cardiometabolic risk factors","volume":"14","author":"Pal","year":"2013","journal-title":"Obes Rev"},{"key":"10.1016\/j.metop.2019.100019_bib3","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.3945\/an.115.011403","article-title":"Systematic review of the association between dairy product consumption and risk of cardiovascular-related clinical outcomes","volume":"7","author":"Drouin-Chartier","year":"2016","journal-title":"Adv Nutr"},{"key":"10.1016\/j.metop.2019.100019_bib4","doi-asserted-by":"crossref","DOI":"10.1186\/s12986-019-0334-y","article-title":"Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation","volume":"16","author":"Fan","year":"2019","journal-title":"Nutr Metab"},{"key":"10.1016\/j.metop.2019.100019_bib5","doi-asserted-by":"crossref","DOI":"10.1186\/1743-7075-10-46","article-title":"Milk protein for improved metabolic health: a review of the evidence","volume":"10","author":"McGregor","year":"2013","journal-title":"Nutr Metab"},{"key":"10.1016\/j.metop.2019.100019_bib6","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1079\/BJN2002760","article-title":"Casein and whey exert different effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetite","volume":"89","author":"Hall","year":"2003","journal-title":"Br J Nutr"},{"key":"10.1016\/j.metop.2019.100019_bib7","doi-asserted-by":"crossref","first-page":"14930","DOI":"10.1073\/pnas.94.26.14930","article-title":"Slow and fast dietary proteins differently modulate postprandial protein accretion","volume":"94","author":"Boirie","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.metop.2019.100019_bib8","first-page":"3011","article-title":"Protein source, quantity, and time of consumption determine the effect of proteins on short-term food intake in young men","volume":"134","author":"Anderson","year":"2004","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.metop.2019.100019_bib9","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/JES.0b013e3182a4e6b6","article-title":"Potential role of branched-chain amino acid catabolism in regulating fat oxidation","volume":"41","author":"Kainulainen","year":"2013","journal-title":"Exerc Sport Sci Rev"},{"key":"10.1016\/j.metop.2019.100019_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmed.2016.00057","article-title":"Branched-chain amino acid levels are related with surrogates of disturbed lipid metabolism among older men","volume":"3","author":"Kujala","year":"2016","journal-title":"Front Med"},{"key":"10.1016\/j.metop.2019.100019_bib11","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.cmet.2010.08.016","article-title":"Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice","volume":"12","author":"D\u2019Antona","year":"2010","journal-title":"Cell Metabol"},{"key":"10.1016\/j.metop.2019.100019_bib12","doi-asserted-by":"crossref","first-page":"157","DOI":"10.2337\/db10-0331","article-title":"Mitochondrial biogenesis and peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1 alpha) deacetylation by physical activity intact adipocytokine signaling is required","volume":"60","author":"Li","year":"2011","journal-title":"Diabetes"},{"key":"10.1016\/j.metop.2019.100019_bib13","first-page":"1479","article-title":"Sirtuin 1 and sirtuin 3: physiological modulators of metabolism","volume":"92","author":"Nogueiras","year":"2012","journal-title":"Phys Rev"},{"key":"10.1016\/j.metop.2019.100019_bib14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/nrm3293","article-title":"Sirtuins as regulators of metabolism and healthspan","volume":"13","author":"Houtkooper","year":"2012","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.metop.2019.100019_bib15","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.molcel.2011.04.028","article-title":"Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase","volume":"43","author":"Jiang","year":"2011","journal-title":"Mol Cell"},{"key":"10.1016\/j.metop.2019.100019_bib16","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cmet.2007.07.003","article-title":"SIRT2 regulates adipocyte differentiation through FoxO1 acetylation\/deacetylation","volume":"6","author":"Jing","year":"2007","journal-title":"Cell Metabol"},{"key":"10.1016\/j.metop.2019.100019_bib17","doi-asserted-by":"crossref","first-page":"771","DOI":"10.18632\/aging.100075","article-title":"Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1 alpha in skeletal muscle","volume":"1","author":"Palacios","year":"2009","journal-title":"Aging-Us"},{"issue":"2011","key":"10.1016\/j.metop.2019.100019_bib18","first-page":"525094","article-title":"Distinct effects of calorie restriction and resveratrol on diet-induced obesity and Fatty liver formation","author":"Tauriainen","year":"2011","journal-title":"J\u00a0Nutr Metab"},{"key":"10.1016\/j.metop.2019.100019_bib19","doi-asserted-by":"crossref","first-page":"14608","DOI":"10.1073\/pnas.1111308108","article-title":"Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production","volume":"108","author":"Jing","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.metop.2019.100019_bib20","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.cmet.2017.03.003","article-title":"SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion","volume":"25","author":"Anderson","year":"2017","journal-title":"Cell Metabol"},{"key":"10.1016\/j.metop.2019.100019_bib21","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1089\/ars.2017.7270","article-title":"Extranuclear sirtuins and metabolic stress","volume":"28","author":"Elkhwanky","year":"2018","journal-title":"Antioxidants Redox Signal"},{"key":"10.1016\/j.metop.2019.100019_bib22","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.tem.2016.10.002","article-title":"SIRT6: novel mechanisms and links to aging and disease","volume":"28","author":"Tasselli","year":"2017","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.metop.2019.100019_bib23","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.cell.2009.12.041","article-title":"The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1 alpha","volume":"140","author":"Zhong","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.metop.2019.100019_bib24","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1080\/21541264.2016.1276658","article-title":"The seven faces of SIRT7","volume":"8","author":"Blank","year":"2017","journal-title":"Transcription"},{"key":"10.1016\/j.metop.2019.100019_bib25","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.cmet.2014.12.021","article-title":"Muscle as a \u201cmediator\u201d of systemic metabolism","volume":"21","author":"Baskin","year":"2015","journal-title":"Cell Metabol"},{"key":"10.1016\/j.metop.2019.100019_bib26","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a029868","article-title":"Theoretical and biological evaluation of the link between low exercise capacity and disease risk","volume":"8","author":"Koch","year":"2018","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10.1016\/j.metop.2019.100019_bib27","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1126\/science.1108177","article-title":"Cardiovascular risk factors emerge after artificial selection for low aerobic capacity","volume":"307","author":"Wisloff","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.metop.2019.100019_bib28","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1113\/jphysiol.2009.169060","article-title":"Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury","volume":"587","author":"Thyfault","year":"2009","journal-title":"J\u00a0Physiol"},{"key":"10.1016\/j.metop.2019.100019_bib29","doi-asserted-by":"crossref","first-page":"18259","DOI":"10.1038\/srep18259","article-title":"Physical activity in adulthood: genes and mortality","volume":"5","author":"Karvinen","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.metop.2019.100019_bib30","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1096\/fj.10-157313","article-title":"Gene expression centroids that link with low intrinsic aerobic exercise capacity and complex disease risk","volume":"24","author":"Kivela","year":"2010","journal-title":"FASEB J"},{"key":"10.1016\/j.metop.2019.100019_bib31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1152\/physiolgenomics.2001.5.1.45","article-title":"Artificial selection for intrinsic aerobic endurance running capacity in rats","volume":"5","author":"Koch","year":"2001","journal-title":"Physiol Genom"},{"key":"10.1016\/j.metop.2019.100019_bib32","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.exger.2016.03.015","article-title":"Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins","volume":"79","author":"Karvinen","year":"2016","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.metop.2019.100019_bib33","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/bdrb.20106","article-title":"The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies","volume":"80","author":"Goldman","year":"2007","journal-title":"Birth Defects Res B Dev Reprod Toxicol"},{"key":"10.1016\/j.metop.2019.100019_bib34","doi-asserted-by":"crossref","first-page":"E307","DOI":"10.1152\/ajpendo.00398.2011","article-title":"Altered REDD1, myostatin, and Akt\/mTOR\/FoxO\/MAPK signaling in streptozotocin-induced diabetic muscle atrophy","volume":"302","author":"Hulmi","year":"2012","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.metop.2019.100019_bib35","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.fct.2013.01.051","article-title":"Resveratrol enhances exercise training responses in rats selectively bred for high running performance","volume":"61","author":"Hart","year":"2013","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.metop.2019.100019_bib36","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1590\/2359-3997000000169","article-title":"Validation of HOMA-IR in a model of insulin-resistance induced by a high-fat diet in Wistar rats","volume":"60","author":"Antunes","year":"2016","journal-title":"Arch Endocrinol Metab"},{"key":"10.1016\/j.metop.2019.100019_bib37","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1038\/oby.2008.513","article-title":"Development of animal models to test the fundamental basis of gene-environment interactions","volume":"16","author":"Koch","year":"2008","journal-title":"Obesity"},{"key":"10.1016\/j.metop.2019.100019_bib38","doi-asserted-by":"crossref","first-page":"57","DOI":"10.2203\/dose-response.13-010.Radak","article-title":"Resveratrol attenuates exercise-induced adaptive responses in rats selectively bred for low running performance","volume":"12","author":"Hart","year":"2014","journal-title":"Dose-Response"},{"key":"10.1016\/j.metop.2019.100019_bib39","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.exger.2013.08.012","article-title":"Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1 alpha","volume":"48","author":"Ringholm","year":"2013","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.metop.2019.100019_bib40","article-title":"The effect of acute and chronic sprint-interval training on LRP130, SIRT3, and PGC-1alpha expression in human skeletal muscle","volume":"4","author":"Edgett","year":"2016","journal-title":"Phys Rep"},{"key":"10.1016\/j.metop.2019.100019_bib41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0071623","article-title":"Dissociation of increases in PGC-1 alpha and its regulators from exercise intensity and muscle activation following acute exercise","volume":"8","author":"Edgett","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.metop.2019.100019_bib42","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3390\/nu11040829","article-title":"Protein supplements and their relation with nutrition, microbiota composition and health: is more protein always better for sportspeople?","volume":"11","author":"Karlund","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.metop.2019.100019_bib43","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0899-9007(00)00552-9","article-title":"The effects of bovine colostrum supplementation on body composition and exercise performance in active men and women","volume":"17","author":"Antonio","year":"2001","journal-title":"Nutrition"},{"key":"10.1016\/j.metop.2019.100019_bib44","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1249\/MSS.0000000000000272","article-title":"Whey protein improves exercise performance and biochemical profiles in trained mice","volume":"46","author":"Chen","year":"2014","journal-title":"Med Sci Sport Exerc"},{"key":"10.1016\/j.metop.2019.100019_bib45","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1038\/s41430-018-0180-4","article-title":"Exercise, energy balance and body composition","volume":"72","author":"Westerterp","year":"2018","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.metop.2019.100019_bib46","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3945\/an.113.003723","article-title":"Effect of dairy proteins on appetite, energy expenditure, body weight, and composition: a review of the evidence from controlled clinical trials","volume":"4","author":"Bendtsen","year":"2013","journal-title":"Adv Nutr"},{"key":"10.1016\/j.metop.2019.100019_bib47","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1017\/S0029665116000264","article-title":"Can milk proteins be a useful tool in the management of cardiometabolic health? An updated review of human intervention trials","volume":"75","author":"Fekete","year":"2016","journal-title":"Proc Nutr Soc"},{"key":"10.1016\/j.metop.2019.100019_bib48","doi-asserted-by":"crossref","DOI":"10.1186\/1476-511X-5-8","article-title":"LDL cholesterol estimation in patients with the metabolic syndrome","volume":"5","author":"Gazi","year":"2006","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.metop.2019.100019_bib49","doi-asserted-by":"crossref","DOI":"10.1038\/ejcn.2016.39","article-title":"Effect of whey protein on blood lipid profiles: a meta-analysis of randomized controlled trials","author":"Zhang","year":"2016","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.metop.2019.100019_bib50","doi-asserted-by":"crossref","first-page":"1235S","DOI":"10.3945\/ajcn.113.073015","article-title":"Yogurt and dairy product consumption to prevent cardiometabolic diseases: epidemiologic and experimental studies","volume":"99","author":"Astrup","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.metop.2019.100019_bib51","unstructured":"Sengupta, P. The laboratory rat: relating its age with human\u2019s. Int J Prev Med. 4, 624-630, PMID: 23930179 (2013)."},{"key":"10.1016\/j.metop.2019.100019_bib52","doi-asserted-by":"crossref","first-page":"260","DOI":"10.7150\/ijms.14586","article-title":"Effect of exercise training on skeletal muscle SIRT1 and PGC-1alpha expression levels in rats of different age","volume":"13","author":"Huang","year":"2016","journal-title":"Int J Med Sci"},{"key":"10.1016\/j.metop.2019.100019_bib53","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.mad.2009.11.002","article-title":"Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats","volume":"131","author":"Koltai","year":"2010","journal-title":"Mech Ageing Dev"},{"key":"10.1016\/j.metop.2019.100019_bib54","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1139\/h11-070","article-title":"Deacetylation of PGC-1 alpha by SIRT1: importance for skeletal muscle function and exercise-induced mitochondrial biogenesis","volume":"36","author":"Gurd","year":"2011","journal-title":"Appl Physiol Nutr Metabol"},{"key":"10.1016\/j.metop.2019.100019_bib55","doi-asserted-by":"crossref","first-page":"30561","DOI":"10.1074\/jbc.M111.261685","article-title":"Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1 alpha) deacetylation following endurance exercise","volume":"286","author":"Philp","year":"2011","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.metop.2019.100019_bib56","article-title":"Regulation of skeletal muscle oxidative capacity and muscle mass by SIRT3","volume":"9","author":"Lin","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.metop.2019.100019_bib57","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1080\/21623945.2015.1122855","article-title":"The protein source determines the potential of high protein diets to attenuate obesity development in C57BL\/6J mice","volume":"5","author":"Liisberg","year":"2016","journal-title":"Adipocyte"},{"key":"10.1016\/j.metop.2019.100019_bib58","doi-asserted-by":"crossref","first-page":"E493","DOI":"10.1152\/ajpendo.00122.2017","article-title":"SIRT6 regulates metabolic homeostasis in skeletal muscle through activation of AMPK","volume":"313","author":"Cui","year":"2017","journal-title":"Am J Physiol Endocrinol Metab"}],"container-title":["Metabolism Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589936819300192?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589936819300192?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T23:53:59Z","timestamp":1762905239000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589936819300192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":58,"alternative-id":["S2589936819300192"],"URL":"https:\/\/doi.org\/10.1016\/j.metop.2019.100019","relation":{},"ISSN":["2589-9368"],"issn-type":[{"value":"2589-9368","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Beneficial effects of running and milk protein supplements on Sirtuins and risk factors of metabolic disorders in rats with low aerobic capacity","name":"articletitle","label":"Article Title"},{"value":"Metabolism Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.metop.2019.100019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100019"}}