{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:39:12Z","timestamp":1791355152011,"version":"4.3.1"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82201867"],"award-info":[{"award-number":["82201867"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Metabolism Open"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.metop.2025.100393","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T15:47:26Z","timestamp":1756914446000},"page":"100393","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["A nonlinear, causal link between serum 25-hydroxyvitamin D and prolactin in type 2 diabetes: Evidence from clinical and Mendelian randomization analyses"],"prefix":"10.1016","volume":"28","author":[{"given":"Jing","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-chuan","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-hong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1849-6523","authenticated-orcid":false,"given":"Cui-ling","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.metop.2025.100393_bib1","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1186\/s12889-025-23786-x","article-title":"Temporal changes in the burden of type 2 diabetes mellitus across the BRICS, 1990-2021: a comprehensive analysis for the global burden of disease study 2021","volume":"25","author":"Wang","year":"2025","journal-title":"BMC Public Health"},{"key":"10.1016\/j.metop.2025.100393_bib2","doi-asserted-by":"crossref","DOI":"10.1007\/s12020-025-04337-1","article-title":"Global, regional, and national burden and trends of type 2 diabetes mellitus among women of childbearing age from 1990 to 2021, with projections to 2030: a systematic analysis for the global burden of disease study 2021","author":"Kong","year":"2025","journal-title":"Endocrine"},{"issue":"1","key":"10.1016\/j.metop.2025.100393_bib3","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1186\/s13098-025-01824-3","article-title":"Cross-country inequalities in the epidemiology of chronic kidney disease due to type 2 diabetes mellitus, 1990-2021: findings from the global burden of disease study 2021","volume":"17","author":"Shan","year":"2025","journal-title":"Diabetol Metab Syndr"},{"issue":"8","key":"10.1016\/j.metop.2025.100393_bib4","article-title":"Arterial stiffness and early cardiac dysfunction in type 2 diabetes mellitus: a potential role for 25 OH vitamin D3 deficiency","volume":"61","author":"Craciun","year":"2025","journal-title":"Medicina (Kaunas)"},{"issue":"6","key":"10.1016\/j.metop.2025.100393_bib5","first-page":"716","article-title":"Effects of oral vitamin D supplementation on vitamin D levels and glycemic parameters in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis","volume":"38","author":"Zhang","year":"2025","journal-title":"Biomed Environ Sci"},{"key":"10.1016\/j.metop.2025.100393_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109641","article-title":"Modifying effects of vitamin D on associations between per- and polyfluoroalkyl substances exposure and risk of gestational diabetes mellitus: a prospective cohort study in beijing, China","volume":"202","author":"Han","year":"2025","journal-title":"Environ Int"},{"issue":"6","key":"10.1016\/j.metop.2025.100393_bib7","article-title":"Significance of duodenal prolactin receptor modulation by calcium and vitamin D in sulpiride-induced hyperprolactinemia","volume":"60","author":"Radojkovic","year":"2024","journal-title":"Medicina (Kaunas)"},{"issue":"10","key":"10.1016\/j.metop.2025.100393_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/nu15102303","article-title":"Vitamin D status determines cardiometabolic effects of cabergoline in women with elevated prolactin levels: a pilot study","volume":"15","author":"Krysiak","year":"2023","journal-title":"Nutrients"},{"issue":"4","key":"10.1016\/j.metop.2025.100393_bib9","first-page":"202","article-title":"Relation between vitamin D and adolescents' serum prolactin","volume":"22","author":"Amanzholkyzy","year":"2023","journal-title":"Prz Menopauzalny"},{"issue":"1","key":"10.1016\/j.metop.2025.100393_bib10","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-10217-5","article-title":"25(OH)vitamin D inflammatory and oxidative stress markers in healthy holstein cows and cows with peri-partum diseases during the transition period","volume":"15","author":"Ahmadi Sheikhsarmast","year":"2025","journal-title":"Sci Rep"},{"issue":"13","key":"10.1016\/j.metop.2025.100393_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/cells14130987","article-title":"Inhibition of the prostaglandin-degrading enzyme 15-Pgdh ameliorates mash-associated apoptosis and fibrosis in mice","volume":"14","author":"Udoh","year":"2025","journal-title":"Cells"},{"issue":"25","key":"10.1016\/j.metop.2025.100393_bib12","doi-asserted-by":"crossref","first-page":"27002","DOI":"10.1021\/acsomega.3c10269","article-title":"Antioxidant, antimicrobial, and anti-inflammatory effects of Liriodendron chinense leaves","volume":"9","author":"Wang","year":"2024","journal-title":"ACS Omega"},{"issue":"1","key":"10.1016\/j.metop.2025.100393_bib13","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1186\/s12931-024-02951-7","article-title":"Vitamin D ameliorates particulate matter induced mitochondrial damages and calcium dyshomeostasis in BEAS-2B human bronchial epithelial cells","volume":"25","author":"Chang-Chien","year":"2024","journal-title":"Respir Res"},{"issue":"1","key":"10.1016\/j.metop.2025.100393_bib14","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1186\/s13098-025-01900-8","article-title":"Estimated glucose disposal rate and risk of cardiovascular events in type 1 diabetes: a systematic review and meta-analysis","volume":"17","author":"Dastjerdi","year":"2025","journal-title":"Diabetol Metab Syndr"},{"issue":"1192","key":"10.1016\/j.metop.2025.100393_bib15","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1093\/postmj\/qgae107","article-title":"Effects of vitamin D supplementation on diabetic foot ulcer healing: a meta-analysis","volume":"101","author":"Wu","year":"2025","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.metop.2025.100393_bib16","article-title":"Associations of cord blood meta-inflammation and vitamin D with neurodevelopmental delay: a prospective birth cohort study in China","volume":"13","author":"Wang","year":"2022","journal-title":"Front Immunol"},{"issue":"3","key":"10.1016\/j.metop.2025.100393_bib17","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3164\/jcbn.20-165","article-title":"Effect of vitamin D supplementation on glycose homeostasis and islet function in vitamin D deficient or insufficient diabetes and prediabetes: a systematic review and meta-analysis","volume":"69","author":"Zou","year":"2021","journal-title":"J Clin Biochem Nutr"},{"issue":"1","key":"10.1016\/j.metop.2025.100393_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13044-024-00214-7","article-title":"Systematic review of the association between thyroid disorders and hyperprolactinemia","volume":"18","author":"Khan","year":"2025","journal-title":"Thyroid Res"},{"issue":"4","key":"10.1016\/j.metop.2025.100393_bib19","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1039\/D4NR03552F","article-title":"Two-photon pumped forward, backward and random lasing in a stilbazolium dye nanocomposite solution containing LAPONITE(R) as a scattering center","volume":"17","author":"He","year":"2025","journal-title":"Nanoscale"}],"container-title":["Metabolism Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589936825000490?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589936825000490?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T06:21:10Z","timestamp":1765520470000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589936825000490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":19,"alternative-id":["S2589936825000490"],"URL":"https:\/\/doi.org\/10.1016\/j.metop.2025.100393","relation":{},"ISSN":["2589-9368"],"issn-type":[{"value":"2589-9368","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A nonlinear, causal link between serum 25-hydroxyvitamin D and prolactin in type 2 diabetes: Evidence from clinical and Mendelian randomization analyses","name":"articletitle","label":"Article Title"},{"value":"Metabolism Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.metop.2025.100393","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100393"}}