{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:15:54Z","timestamp":1786994154861,"version":"build-2736575974"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,3,5]],"date-time":"2019-03-05T00:00:00Z","timestamp":1551744000000},"content-version":"vor","delay-in-days":63,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Canadian Association of Pediatric Surgeons Research Grant"},{"name":"Western University, Schulich School of Medicine and Dentistry, Department of Surgery Research Grant"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["MethodsX"],"published-print":{"date-parts":[[2019]]},"DOI":"10.1016\/j.mex.2019.03.001","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T03:25:17Z","timestamp":1553225117000},"page":"594-600","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Surgical technique for developing a rabbit model of congenital diaphragmatic hernia and tracheal occlusion"],"prefix":"10.1016","volume":"6","author":[{"given":"M.","family":"Mudri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5612-6807","authenticated-orcid":false,"given":"S.A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Vander Tuin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Davidson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1930-8358","authenticated-orcid":false,"given":"T.R.H.","family":"Regnault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"B\u00fctter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mex.2019.03.001_bib0005","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1007\/s00268-007-9074-7","article-title":"Fetal tracheal occlusion for the treatment of congenital diaphragmatic hernia","volume":"31","author":"Laberge","year":"2007","journal-title":"World J. Surg."},{"key":"10.1016\/j.mex.2019.03.001_bib0010","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1053\/j.semperi.2004.03.009","article-title":"The CDH Study Group and advances in the clinical care of the patient with congenital diaphragmatic hernia","volume":"28","author":"Doyle","year":"2004","journal-title":"Semin. Perinatol."},{"key":"10.1016\/j.mex.2019.03.001_bib0015","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.amjsurg.2005.05.035","article-title":"Congenital diaphragmatic hernia: searching for answers","volume":"190","author":"Gosche","year":"2005","journal-title":"Am. J. Surg."},{"key":"10.1016\/j.mex.2019.03.001_bib0020","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.jpedsurg.2006.01.026","article-title":"The price of success in the management of congenital diaphragmatic hernia: is improved survival accompanied by an increase in long-term morbidity?","volume":"41","author":"Chiu","year":"2006","journal-title":"J. Pediatr. Surg."},{"key":"10.1016\/j.mex.2019.03.001_bib0025","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0022-3468(94)90328-X","article-title":"Experimental fetal tracheal ligation reverses the structural and physiological effects of pulmonary hypoplasia in congenital diaphragmatic hernia","volume":"29","author":"DiFiore","year":"1994","journal-title":"J. Pediatr. Surg."},{"key":"10.1016\/j.mex.2019.03.001_bib0030","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1016\/S0022-3468(97)90314-6","article-title":"Tracheoscopic endotracheal occlusion in the ovine model: technique and pulmonary effects","volume":"32","author":"Flageole","year":"1997","journal-title":"J. Pediatr. Surg."},{"key":"10.1016\/j.mex.2019.03.001_bib0035","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1159\/000209850","article-title":"Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation","volume":"96","author":"Van Loenhout","year":"2009","journal-title":"Neonatology"},{"key":"10.1016\/j.mex.2019.03.001_bib0040","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/BF00303142","article-title":"Experimental study on embryogenesis of congenital diaphragmatic hernia","volume":"169","author":"Iritani","year":"1984","journal-title":"Anat. Embryol. (Berl.)"},{"key":"10.1016\/j.mex.2019.03.001_bib0045","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/S0002-9440(10)65000-6","article-title":"Dual-hit hypothesis explains pulmonary hypoplasia in the nitrofen model of congenital diaphragmatic hernia","volume":"156","author":"Keijzer","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.mex.2019.03.001_bib0050","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/0022-3468(90)90190-K","article-title":"Nitrofen-induced diaphragmatic hernias in rats: an animal model","volume":"25","author":"Kluth","year":"1990","journal-title":"J. Pediatr. Surg."},{"key":"10.1016\/j.mex.2019.03.001_bib0055","first-page":"1","article-title":"Prenatal microRNA miR-200b therapy improves nitrofen-induced pulmonary hypoplasia associated with congenital diaphragmatic hernia","author":"Khoshgoo","year":"2017","journal-title":"Ann. Surg."},{"key":"10.1016\/j.mex.2019.03.001_bib0060","first-page":"12","article-title":"Hypoplastic lungs in fetal lambs with surgically produced congenital diaphragmatic hernia","volume":"62","author":"Delorimier AA","year":"1967","journal-title":"Surgery"},{"key":"10.1016\/j.mex.2019.03.001_bib0065","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/0022-3468(94)90008-6","article-title":"Surgically produced congenital diaphragmatic hernia in fetal rabbits","volume":"29","author":"Fauza","year":"1994","journal-title":"J. Pediatr. Surg."},{"key":"10.1016\/j.mex.2019.03.001_bib0070","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1093\/humrep\/15.12.2483","article-title":"Lung development following diaphragmatic hernia in the fetal rabbit","volume":"15","author":"Wu","year":"2000","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.mex.2019.03.001_bib0075","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0069210","article-title":"Alveolarization genes modulated by fetal tracheal occlusion in the rabbit model for congenital diaphragmatic hernia: a randomized study","volume":"8","author":"Vuckovic","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mex.2019.03.001_bib0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpedsurg.2019.01.024","article-title":"The effects of tracheal occlusion on Wnt signaling in a rabbit model of congenital diaphragmatic hernia","author":"Mudri","year":"2019","journal-title":"J. Pediatr. Surg."}],"container-title":["MethodsX"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2215016119300469?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2215016119300469?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T05:50:50Z","timestamp":1762408250000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2215016119300469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":16,"alternative-id":["S2215016119300469"],"URL":"https:\/\/doi.org\/10.1016\/j.mex.2019.03.001","relation":{},"ISSN":["2215-0161"],"issn-type":[{"value":"2215-0161","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Surgical technique for developing a rabbit model of congenital diaphragmatic hernia and tracheal occlusion","name":"articletitle","label":"Article Title"},{"value":"MethodsX","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mex.2019.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}