{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:02:25Z","timestamp":1791302545577,"version":"4.1.0"},"reference-count":11,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T00:00:00Z","timestamp":1586476800000},"content-version":"vor","delay-in-days":100,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1059B191800458"],"award-info":[{"award-number":["1059B191800458"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK121351"],"award-info":[{"award-number":["DK121351"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["EB02264"],"award-info":[{"award-number":["EB02264"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["MethodsX"],"published-print":{"date-parts":[[2020]]},"DOI":"10.1016\/j.mex.2020.100896","type":"journal-article","created":{"date-parts":[[2020,4,22]],"date-time":"2020-04-22T01:48:32Z","timestamp":1587520112000},"page":"100896","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["A modified and simplified method for purification of gold nanoparticles"],"prefix":"10.1016","volume":"7","author":[{"given":"Irem","family":"Kulu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavna","family":"Kalyanaraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent M.","family":"Rotello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.mex.2020.100896_bib0001","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1039\/C39940000801","article-title":"Synthesis of thiol-derivatised gold nanoparticles in a two-phase Liquid\u2013Liquid system","author":"Brust","year":"1994","journal-title":"J. Chem. Soc. Chem. Commun."},{"issue":"4","key":"10.1016\/j.mex.2020.100896_bib0002","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1021\/ja808137c","article-title":"Entrapment of Hydrophobic Drugs in Nanoparticle Monolayers with Efficient Release into Cancer Cells","volume":"131","author":"Kim","year":"2009","journal-title":"J. Am. Chem. Soc."},{"issue":"3","key":"10.1016\/j.mex.2020.100896_bib0003","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1007\/s00216-009-3250-6","article-title":"Laser desorption\/ionization mass spectrometry analysis of monolayer-protected gold nanoparticles","volume":"396","author":"Yan","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"issue":"6","key":"10.1016\/j.mex.2020.100896_bib0004","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1039\/C1NR11188D","article-title":"preparation, properties, and applications in bionanotechnology","volume":"4","author":"Yeh","year":"2012","journal-title":"Nanoscale"},{"issue":"1","key":"10.1016\/j.mex.2020.100896_bib0005","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1021\/la970588w","article-title":"Alkanethiolate gold cluster molecules with core diameters from 1.5 to 5.2 nm:\u2009 core and monolayer properties as a function of core size","volume":"14","author":"Hostetler","year":"1998","journal-title":"Langmuir"},{"issue":"11","key":"10.1016\/j.mex.2020.100896_bib0006","doi-asserted-by":"crossref","first-page":"3782","DOI":"10.1021\/la981598f","article-title":"Dynamics of place-exchange reactions on monolayer-protected gold cluster molecules","volume":"15","author":"Hostetler","year":"1999","journal-title":"Langmuir"},{"issue":"7","key":"10.1016\/j.mex.2020.100896_bib0007","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1021\/ja0457718","article-title":"Thiol-functionalized, 1.5-nm gold nanoparticles through ligand exchange reactions:\u2009 scope and mechanism of ligand exchange","volume":"127","author":"Woehrle","year":"2005","journal-title":"J. Am. Chem. Soc."},{"issue":"1","key":"10.1016\/j.mex.2020.100896_bib0008","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/smll.200901158","article-title":"Effect of surface properties on nanoparticle\u2013cell interactions","volume":"6","author":"Verma","year":"2010","journal-title":"Small"},{"issue":"1","key":"10.1016\/j.mex.2020.100896_bib0009","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jconrel.2010.06.004","article-title":"Gold nanoparticle platforms as drug and biomacromolecule delivery systems","volume":"148","author":"Duncan","year":"2010","journal-title":"J. Controlled Release"},{"issue":"10","key":"10.1016\/j.mex.2020.100896_bib0010","doi-asserted-by":"crossref","first-page":"3190","DOI":"10.1021\/ja0558241","article-title":"Rapid purification and size separation of gold nanoparticles via diafiltration","volume":"128","author":"Sweeney","year":"2006","journal-title":"J. Am. Chem. Soc."},{"issue":"1","key":"10.1016\/j.mex.2020.100896_bib0011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0003-2670(00)01256-3","article-title":"Fluidics and sample handling in clinical chemical analysis","volume":"429","author":"Cunningham","year":"2001","journal-title":"Anal. Chim. Acta"}],"container-title":["MethodsX"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2215016120301151?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2215016120301151?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:44:00Z","timestamp":1791301440000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2215016120301151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":11,"alternative-id":["S2215016120301151"],"URL":"https:\/\/doi.org\/10.1016\/j.mex.2020.100896","relation":{},"ISSN":["2215-0161"],"issn-type":[{"value":"2215-0161","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A modified and simplified method for purification of gold nanoparticles","name":"articletitle","label":"Article Title"},{"value":"MethodsX","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mex.2020.100896","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"100896"}}