{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:47:51Z","timestamp":1791928071670,"version":"4.3.4"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["MethodsX"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.mex.2026.104186","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:16:07Z","timestamp":1790694967000},"page":"104186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Surface-guided radiotherapy setup using an open-face mask for head and neck cancer; the OPEN trial approach"],"prefix":"10.1016","volume":"17","author":[{"given":"Samantha","family":"Ryan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9048-4868","authenticated-orcid":false,"given":"Claire","family":"Fitzpatrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4598-5178","authenticated-orcid":false,"given":"Ciaran","family":"Malone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Tynan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Harwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clodagh","family":"Callagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Woods","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinead","family":"Brennan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7301-3329","authenticated-orcid":false,"given":"Jill","family":"Nicholson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.mex.2026.104186_bib0001","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/jmrs.308","article-title":"Exploring the prevalence and experience of mask anxiety for the person with head and neck cancer undergoing radiotherapy","volume":"65","author":"Nixon","year":"2018","journal-title":"J. Med. Radiat. Sci."},{"issue":"3","key":"10.1016\/j.mex.2026.104186_bib0002","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/jmrs.658","article-title":"\u2018Having the mask on didn\u2019t worry me until \u2026 they clamped my head down so I wouldn\u2019t move\u2019: a qualitative study exploring anxiety in patients with head and neck cancer during radiation therapy","volume":"70","author":"Forbes","year":"2023","journal-title":"J. Med. Radiat. Sci."},{"issue":"5","key":"10.1016\/j.mex.2026.104186_bib0003","article-title":"Trajectory of anxiety related to radiation therapy mask immobilization and treatment delivery in head and neck cancer and radiation therapists\u2019 ability to detect this anxiety","volume":"7","author":"Burns","year":"2022","journal-title":"Adv Radiat Oncol."},{"issue":"12","key":"10.1016\/j.mex.2026.104186_bib0004","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1002\/pon.1854","article-title":"Disruption to radiation therapy sessions due to anxiety among patients receiving radiation therapy to the head and neck area can be predicted using patient self-report measures","volume":"20","author":"Clover","year":"2011","journal-title":"Psychooncology"},{"issue":"3","key":"10.1016\/j.mex.2026.104186_bib0005","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/jmrs.346","article-title":"A prospective examination of mask anxiety during radiotherapy for head and neck cancer and patient perceptions of management strategies","volume":"66","author":"Nixon","year":"2019","journal-title":"J. Med. Radiat. Sci."},{"issue":"16","key":"10.1016\/j.mex.2026.104186_bib0006","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.3390\/cancers16162899","article-title":"Open-face masks in radiotherapy: enhancing therapeutic strategies for head and neck and brain cancer patients\u2014a comprehensive scoping review","volume":"16","author":"Lastrucci","year":"2024","journal-title":"Cancers (Basel)"},{"issue":"2","key":"10.1016\/j.mex.2026.104186_bib0007","doi-asserted-by":"crossref","first-page":"219","DOI":"10.5603\/rpor.99905","article-title":"Unmasking anxiety: a head-to-head comparison of open and closed masks in head and neck cancer radiotherapy","volume":"29","author":"Glynn","year":"2024","journal-title":"Rep. Pract. Oncol. Radiother."},{"issue":"1","key":"10.1016\/j.mex.2026.104186_bib0008","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/jmrs.825","article-title":"Open or closed: experience of head and neck radiotherapy masks\u2014a mixed-methods study","volume":"72","author":"Lundin","year":"2025","journal-title":"J. Med. Radiat. Sci."},{"issue":"3","key":"10.1016\/j.mex.2026.104186_bib0009","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.semradonc.2018.02.003","article-title":"The role of optical surface imaging systems in radiation therapy","volume":"28","author":"Hoisak","year":"2018","journal-title":"Semin. Radiat. Oncol."},{"issue":"5","key":"10.1016\/j.mex.2026.104186_bib0010","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.4103\/jcrt.JCRT_1147_21","article-title":"Review of clinical applications and challenges with surface-guided radiation therapy","volume":"19","author":"Bellala","year":"2023","journal-title":"Cancer Res. Ther."},{"issue":"6","key":"10.1016\/j.mex.2026.104186_bib0011","doi-asserted-by":"crossref","first-page":"E37","DOI":"10.1097\/NCC.0000000000000231","article-title":"Predictors for weight loss in head and neck cancer patients undergoing radiotherapy: a systematic review","volume":"38","author":"Zhao","year":"2015","journal-title":"Cancer Nurs."},{"key":"10.1016\/j.mex.2026.104186_bib0012","article-title":"Feasibility of transitioning to marker-less immobilisation using optical surface guidance in head and neck cancer treatment: a study at territory state cancer centre in a developing country","volume":"37","author":"Thirunavukarasu","year":"2026","journal-title":"Tech. Innov. Patient Support Radiat. Oncol."},{"key":"10.1016\/j.mex.2026.104186_bib0013","doi-asserted-by":"crossref","DOI":"10.1177\/15330338241271946","article-title":"Feasibility of a novel surface-guided setup technique to reproduce neck curvature using two regions of interest","volume":"23","author":"Li","year":"2024","journal-title":"Technol. Cancer Res. Treat."},{"key":"10.1016\/j.mex.2026.104186_bib0014","doi-asserted-by":"crossref","first-page":"60","DOI":"10.12688\/hrbopenres.14112.1","article-title":"Trial protocol: OPEN: optimising patient experience in head and neck radiotherapy, a phase 3 randomised control trial comparing open versus closed face masks for patients undergoing head and neck radiotherapy","volume":"8","author":"Nicholson","year":"2025","journal-title":"HRB Open Res."},{"key":"10.1016\/j.mex.2026.104186_bib0015","unstructured":"Nicholson J., Ryan S., Malone C., Fitzpatrick C., O\u2019Maolalai R., O\u2019Donovan R., et al. OPEN: optimising patient experience in head and neck radiotherapy, a phase 3 randomised control trial comparing open versus closed face masks. Radiother. Oncol. In press."},{"key":"10.1016\/j.mex.2026.104186_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.110941","article-title":"Intrafraction motion stability of open vs. closed facemasks in head and neck radiotherapy: insights from the OPEN phase III trial","volume":"209","author":"Malone","year":"2025","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.mex.2026.104186_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.111173","article-title":"From rugged ridges to radiotherapy ROIs: translating topographical metrics to surface-guided radiation therapy regions of interest in radiotherapy","volume":"213","author":"Malone","year":"2025","journal-title":"Radiother. Oncol."}],"container-title":["MethodsX"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2215016126004024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2215016126004024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:25:22Z","timestamp":1791926722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2215016126004024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":17,"alternative-id":["S2215016126004024"],"URL":"https:\/\/doi.org\/10.1016\/j.mex.2026.104186","relation":{},"ISSN":["2215-0161"],"issn-type":[{"value":"2215-0161","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Surface-guided radiotherapy setup using an open-face mask for head and neck cancer; the OPEN trial approach","name":"articletitle","label":"Article Title"},{"value":"MethodsX","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mex.2026.104186","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104186"}}