{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:44:59Z","timestamp":1789915499344,"version":"4.0.1"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["CRC1181-A06"],"award-info":[{"award-number":["CRC1181-A06"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01KI1726A"],"award-info":[{"award-number":["01KI1726A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01KI1726C"],"award-info":[{"award-number":["01KI1726C"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmn.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Microbiology"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.mib.2018.11.010","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T00:24:39Z","timestamp":1547166279000},"page":"59-65","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Modulation of host cell metabolism by T4SS-encoding intracellular pathogens"],"prefix":"10.1016","volume":"47","author":[{"given":"Inaya","family":"Hayek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7500-5864","authenticated-orcid":false,"given":"Christian","family":"Berens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"L\u00fchrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mib.2018.11.010_bib0005","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/mmi.13896","article-title":"Type IV secretion in Gram-negative and Gram-positive bacteria","volume":"107","author":"Grohmann","year":"2018","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0010","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3389\/fcimb.2018.00003","article-title":"The life cycle of L. pneumophila: cellular differentiation is linked to virulence and metabolism","volume":"8","author":"Oliva","year":"2018","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0015","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3389\/fcimb.2013.00024","article-title":"Metabolic host responses to infection by intracellular bacterial pathogens","volume":"3","author":"Eisenreich","year":"2013","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0020","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jinf.2006.10.048","article-title":"Q fever","volume":"54","author":"Cutler","year":"2007","journal-title":"J Infect"},{"key":"10.1016\/j.mib.2018.11.010_bib0025","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s13690-017-0248-y","article-title":"Farming, Q fever and public health: agricultural practices and beyond","volume":"76","author":"Mori","year":"2018","journal-title":"Arch Public Health"},{"key":"10.1016\/j.mib.2018.11.010_bib0030","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/978-1-4614-0204-6_12","article-title":"Q fever: still more queries than answers","volume":"719","author":"Delsing","year":"2011","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.mib.2018.11.010_bib0035","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1128\/CMR.12.4.518","article-title":"Q fever","volume":"12","author":"Maurin","year":"1999","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.mib.2018.11.010_bib0040","doi-asserted-by":"crossref","first-page":"e00175","DOI":"10.1128\/mBio.00175-11","article-title":"Dot\/Icm type IVB secretion system requirements for Coxiella burnetii growth in human macrophages","volume":"2","author":"Beare","year":"2011","journal-title":"MBio"},{"key":"10.1016\/j.mib.2018.11.010_bib0045","doi-asserted-by":"crossref","first-page":"e1002056","DOI":"10.1371\/journal.ppat.1002056","article-title":"The Coxiella burnetii Dot\/Icm system delivers a unique repertoire of type IV effectors into host cells and is required for intracellular replication","volume":"7","author":"Carey","year":"2011","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2018.11.010_bib0050","first-page":"243","article-title":"Beginning to understand the role of the type iv secretion system effector proteins in Coxiella burnetii pathogenesis","volume":"413","author":"L\u00fchrmann","year":"2017","journal-title":"Curr Top Microbiol Immunol"},{"key":"10.1016\/j.mib.2018.11.010_bib0055","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S1369-5274(99)80005-8","article-title":"Cell biology of Legionella pneumophila","volume":"2","author":"Vogel","year":"1999","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0060","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1146\/annurev-micro-102215-095557","article-title":"Autophagy evasion and endoplasmic reticulum subversion: the Yin and Yang of Legionella intracellular infection","volume":"70","author":"Sherwood","year":"2016","journal-title":"Annu Rev Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0065","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1111\/cmi.12452","article-title":"The changing nature of the Brucella-containing vacuole","volume":"17","author":"Celli","year":"2015","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0070","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.cll.2017.01.006","article-title":"Tick-borne emerging infections: ehrlichiosis and anaplasmosis","volume":"37","author":"Ismail","year":"2017","journal-title":"Clin Lab Med"},{"key":"10.1016\/j.mib.2018.11.010_bib0075","first-page":"297","article-title":"Role and function of the type IV secretion system in Anaplasma and Ehrlichia species","volume":"413","author":"Rikihisa","year":"2017","journal-title":"Curr Top Microbiol Immunol"},{"key":"10.1016\/j.mib.2018.11.010_bib0080","doi-asserted-by":"crossref","first-page":"E8977","DOI":"10.1073\/pnas.1806904115","article-title":"Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation","volume":"115","author":"Yan","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2018.11.010_bib0085","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.ijmm.2017.11.001","article-title":"Metabolic adaptation of intracellular bacteria and fungi to macrophages","volume":"308","author":"Sprenger","year":"2018","journal-title":"Int J Med Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0090","doi-asserted-by":"crossref","first-page":"316","DOI":"10.3389\/fcimb.2017.00316","article-title":"To eat and to be eaten: mutual metabolic adaptations of immune cells and intracellular bacterial pathogens upon infection","volume":"7","author":"Eisenreich","year":"2017","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0095","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3389\/fcimb.2017.00285","article-title":"Multiple substrate usage of Coxiella burnetii to feed a bipartite metabolic network","volume":"7","author":"H\u00e4uslein","year":"2017","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0100","doi-asserted-by":"crossref","first-page":"3868","DOI":"10.1002\/1873-3468.12326","article-title":"The life stage-specific pathometabolism of Legionella pneumophila","volume":"590","author":"Eisenreich","year":"2016","journal-title":"FEBS Lett"},{"key":"10.1016\/j.mib.2018.11.010_bib0105","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/path.2697","article-title":"Autophagy: cellular and molecular mechanisms","volume":"221","author":"Glick","year":"2010","journal-title":"J Pathol"},{"key":"10.1016\/j.mib.2018.11.010_bib0110","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.3389\/fimmu.2017.01483","article-title":"Macrophage autophagy and bacterial infection","volume":"8","author":"Bah","year":"2017","journal-title":"Front Immunol"},{"key":"10.1016\/j.mib.2018.11.010_bib0115","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1111\/j.1462-5822.2005.00527.x","article-title":"Autophagy induction favours the generation and maturation of the Coxiella-replicative vacuoles","volume":"7","author":"Gutierrez","year":"2005","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0120","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.mib.2015.09.004","article-title":"Dining in: intracellular bacterial pathogen interplay with autophagy","volume":"29","author":"Winchell","year":"2016","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0125","doi-asserted-by":"crossref","first-page":"919","DOI":"10.2217\/fmb-2016-0044","article-title":"Right on Q: genetics begin to unravel Coxiella burnetii host cell interactions","volume":"11","author":"Larson","year":"2016","journal-title":"Future Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0130","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1128\/JB.00180-13","article-title":"Refining the plasmid-encoded type IV secretion system substrate repertoire of Coxiella burnetii","volume":"195","author":"Maturana","year":"2013","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2018.11.010_bib0135","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1128\/JB.01359-10","article-title":"The Coxiella burnetii cryptic plasmid is enriched in genes encoding type IV secretion system substrates","volume":"193","author":"Voth","year":"2011","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2018.11.010_sbref0140","doi-asserted-by":"crossref","first-page":"E3260","DOI":"10.1073\/pnas.1522811113","article-title":"Coxiella burnetii effector CvpB modulates phosphoinositide metabolism for optimal vacuole development","volume":"113","author":"Martinez","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2018.11.010_sbref0145","article-title":"Effector protein Cig2 decreases host tolerance of infection by directing constitutive fusion of autophagosomes with the Coxiella-containing vacuole","volume":"7","author":"Kohler","year":"2016","journal-title":"MBio"},{"key":"10.1016\/j.mib.2018.11.010_bib0150","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1128\/IAI.01236-13","article-title":"Coxiella burnetii type IV secretion-dependent recruitment of macrophage autophagosomes","volume":"82","author":"Winchell","year":"2014","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2018.11.010_sbref0155","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3389\/fcimb.2017.00190","article-title":"Physicochemical and nutritional requirements for axenic replication suggest physiological basis for Coxiella burnetii niche restriction","volume":"7","author":"Vallejo Esquerra","year":"2017","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0160","doi-asserted-by":"crossref","first-page":"20800","DOI":"10.1073\/pnas.1218674109","article-title":"Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection","volume":"109","author":"Niu","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2018.11.010_sbref0165","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1080\/15548627.2016.1217369","article-title":"Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase","volume":"12","author":"Lin","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.mib.2018.11.010_bib0170","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1371\/journal.pgen.0020021","article-title":"Comparative genomics of emerging human ehrlichiosis agents","volume":"2","author":"Dunning Hotopp","year":"2006","journal-title":"PLoS Genet"},{"key":"10.1016\/j.mib.2018.11.010_sbref0175","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.1128\/AEM.00261-16","article-title":"Complementation of arginine auxotrophy for genetic transformation of Coxiella burnetii by use of a defined axenic medium","volume":"82","author":"Sandoz","year":"2016","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0180","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1128\/jb.148.2.419-425.1981","article-title":"Stability of the adenosine 5'-triphosphate pool in Coxiella burnetii: influence of pH and substrate","volume":"148","author":"Hackstadt","year":"1981","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2018.11.010_bib0185","doi-asserted-by":"crossref","first-page":"5455","DOI":"10.1073\/pnas.0931379100","article-title":"Complete genome sequence of the Q-fever pathogen Coxiella burnetii","volume":"100","author":"Seshadri","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2018.11.010_bib0190","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1128\/IAI.00294-15","article-title":"Selective requirement of the shikimate pathway of Legionella pneumophila for intravacuolar growth within human macrophages but not within Acanthamoeba","volume":"83","author":"Jones","year":"2015","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2018.11.010_bib0195","doi-asserted-by":"crossref","first-page":"9924","DOI":"10.1073\/pnas.0502767102","article-title":"The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages","volume":"102","author":"Sauer","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2018.11.010_bib0200","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1111\/j.1365-2958.2005.04490.x","article-title":"Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5","volume":"55","author":"Wieland","year":"2005","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0205","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1126\/science.1212868","article-title":"Host proteasomal degradation generates amino acids essential for intracellular bacterial growth","volume":"334","author":"Price","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.mib.2018.11.010_sbref0210","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1016\/j.celrep.2017.10.088","article-title":"Positive and negative regulation of the master metabolic regulator mTORC1 by two families of Legionella pneumophila effectors","volume":"21","author":"De Leon","year":"2017","journal-title":"Cell Rep"},{"key":"10.1016\/j.mib.2018.11.010_sbref0215","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.chom.2017.07.020","article-title":"Legionella pneumophila modulates mitochondrial dynamics to trigger metabolic repurposing of infected macrophages","volume":"22","author":"Escoll","year":"2017","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.mib.2018.11.010_bib0220","doi-asserted-by":"crossref","first-page":"4232","DOI":"10.1128\/JB.01656-08","article-title":"The Coxiella burnetii ankyrin repeat domain-containing protein family is heterogeneous, with C-terminal truncations that influence Dot\/Icm-mediated secretion","volume":"191","author":"Voth","year":"2009","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2018.11.010_bib0225","doi-asserted-by":"crossref","first-page":"3914","DOI":"10.1128\/JB.00071-13","article-title":"Identification of Coxiella burnetii type IV secretion substrates required for intracellular replication and Coxiella-containing vacuole formation","volume":"195","author":"Weber","year":"2013","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2018.11.010_bib0230","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.01046-16","article-title":"A farnesylated Coxiella burnetii effector forms a multimeric complex at the mitochondrial outer membrane during infection","volume":"85","author":"Fielden","year":"2017","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2018.11.010_bib0235","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/mmi.13313","article-title":"Pathway analysis using (13) C-glycerol and other carbon tracers reveals a bipartite metabolism of Legionella pneumophila","volume":"100","author":"Hauslein","year":"2016","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0240","doi-asserted-by":"crossref","first-page":"5000","DOI":"10.1128\/AEM.01018-16","article-title":"Metabolism of myo-Inositol by Legionella pneumophila promotes infection of amoebae and macrophages","volume":"82","author":"Manske","year":"2016","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0245","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3389\/fcimb.2016.00153","article-title":"A T4SS effector targets host cell alpha-enolase contributing to Brucella abortus intracellular lifestyle","volume":"6","author":"Marchesini","year":"2016","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0250","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.bbalip.2014.09.011","article-title":"Phosphoinositides and host-pathogen interactions","volume":"1851","author":"Pizarro-Cerda","year":"2015","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.mib.2018.11.010_bib0255","doi-asserted-by":"crossref","first-page":"3989","DOI":"10.1128\/IAI.00785-15","article-title":"Legionella pneumophila effector LpdA Is a palmitoylated phospholipase D virulence factor","volume":"83","author":"Schroeder","year":"2015","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2018.11.010_bib0260","doi-asserted-by":"crossref","first-page":"4560","DOI":"10.1073\/pnas.1316376111","article-title":"VipD is a Rab5-activated phospholipase A1 that protects Legionella pneumophila from endosomal fusion","volume":"111","author":"Gaspar","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2018.11.010_bib0265","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1073\/pnas.1522067113","article-title":"Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy","volume":"113","author":"Rolando","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2018.11.010_bib0270","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.12637","article-title":"Interactions between the Coxiella burnetii parasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L","volume":"19","author":"Justis","year":"2017","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0275","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1091\/mbc.e12-10-0760","article-title":"Adenovirus RIDalpha uncovers a novel pathway requiring ORP1L for lipid droplet formation independent of NPC1","volume":"24","author":"Cianciola","year":"2013","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.mib.2018.11.010_bib0280","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1146\/annurev-biochem-061009-102430","article-title":"Lipid droplets and cellular lipid metabolism","volume":"81","author":"Walther","year":"2012","journal-title":"Annu Rev Biochem"},{"key":"10.1016\/j.mib.2018.11.010_bib0285","doi-asserted-by":"crossref","first-page":"44507","DOI":"10.1074\/jbc.M207712200","article-title":"The surface of lipid droplets is a phospholipid monolayer with a unique fatty acid composition","volume":"277","author":"Tauchi-Sato","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mib.2018.11.010_bib0290","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.devcel.2015.06.007","article-title":"Protein crowding is a determinant of lipid droplet protein composition","volume":"34","author":"Kory","year":"2015","journal-title":"Dev Cell"},{"key":"10.1016\/j.mib.2018.11.010_bib0295","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.cell.2009.11.005","article-title":"Lipid droplets finally get a little R-E-S-P-E-C-T","volume":"139","author":"Farese","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.mib.2018.11.010_bib0300","doi-asserted-by":"crossref","DOI":"10.15252\/embj.201898947","article-title":"The assembly of lipid droplets and their roles in challenged cells","volume":"37","author":"Henne","year":"2018","journal-title":"EMBO J"},{"key":"10.1016\/j.mib.2018.11.010_bib0305","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.yexcr.2015.10.028","article-title":"Lipid droplets in leukocytes: organelles linked to inflammatory responses","volume":"340","author":"Melo","year":"2016","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.mib.2018.11.010_bib0310","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1074\/jbc.R111.300202","article-title":"Emerging role of lipid droplets in host\/pathogen interactions","volume":"287","author":"Herker","year":"2012","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mib.2018.11.010_bib0315","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0002-9343(94)90325-5","article-title":"Immunohistologic demonstration of Coxiella burnetii in the valves of patients with Q fever endocarditis","volume":"97","author":"Brouqui","year":"1994","journal-title":"Am J Med"},{"key":"10.1016\/j.mib.2018.11.010_bib0320","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1111\/cmi.12096","article-title":"Virulent Coxiella burnetii pathotypes productively infect primary human alveolar macrophages","volume":"15","author":"Graham","year":"2013","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0325","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1111\/j.1749-6632.2003.tb07447.x","article-title":"Comparative DNA microarray analysis of host cell transcriptional responses to infection by Coxiella burnetii or Chlamydia trachomatis","volume":"990","author":"Ren","year":"2003","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.mib.2018.11.010_bib0330","doi-asserted-by":"crossref","first-page":"e0192215","DOI":"10.1371\/journal.pone.0192215","article-title":"Altering lipid droplet homeostasis affects Coxiella burnetii intracellular growth","volume":"13","author":"Mulye","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2018.11.010_bib0335","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/j.1600-0854.2012.01339.x","article-title":"Lipid droplet de novo formation and fission are linked to the cell cycle in fission yeast","volume":"13","author":"Long","year":"2012","journal-title":"Traffic"},{"key":"10.1016\/j.mib.2018.11.010_bib0340","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s12013-017-0792-7","article-title":"High cholesterol\/low cholesterol: effects in biological membranes: a review","volume":"75","author":"Subczynski","year":"2017","journal-title":"Cell Biochem Biophys"},{"key":"10.1016\/j.mib.2018.11.010_bib0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamem.2018.05.002","article-title":"Dynamic pattern generation in cell membranes: current insights into membrane organization","author":"Raghunathan","year":"2018","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.mib.2018.11.010_bib0350","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3389\/fcimb.2017.00165","article-title":"Manipulation of host cholesterol by obligate intracellular bacteria","volume":"7","author":"Samanta","year":"2017","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0355","doi-asserted-by":"crossref","first-page":"e1003107","DOI":"10.1371\/journal.ppat.1003107","article-title":"Bacterial colonization of host cells in the absence of cholesterol","volume":"9","author":"Gilk","year":"2013","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2018.11.010_bib0360","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02313-16","article-title":"Elevated cholesterol in the Coxiella burnetii intracellular niche is bacteriolytic","volume":"8","author":"Mulye","year":"2017","journal-title":"MBio"},{"key":"10.1016\/j.mib.2018.11.010_bib0365","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1529\/biophysj.104.048926","article-title":"Desmosterol may replace cholesterol in lipid membranes","volume":"88","author":"Huster","year":"2005","journal-title":"Biophys J"},{"key":"10.1016\/j.mib.2018.11.010_bib0370","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1111\/j.1462-5822.2005.00641.x","article-title":"Coxiella burnetii inhabits a cholesterol-rich vacuole and influences cellular cholesterol metabolism","volume":"8","author":"Howe","year":"2006","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.mib.2018.11.010_bib0375","doi-asserted-by":"crossref","first-page":"6154","DOI":"10.1128\/JB.00818-10","article-title":"Coxiella burnetii expresses a functional Delta24 sterol reductase","volume":"192","author":"Gilk","year":"2010","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2018.11.010_bib0380","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1756-0500-2-51","article-title":"Evidence that the intra-amoebal Legionella drancourtii acquired a sterol reductase gene from eukaryotes","volume":"2","author":"Moliner","year":"2009","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.mib.2018.11.010_bib0385","doi-asserted-by":"crossref","first-page":"e00471","DOI":"10.1128\/genomeA.00471-17","article-title":"Whole-genome sequence of Coxiella burnSetii nine mile RSA439 (phase ii, clone 4), a laboratory workhorse strain","volume":"5","author":"Millar","year":"2017","journal-title":"Genome Announc"}],"container-title":["Current Opinion in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1369527418300596?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1369527418300596?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T05:48:33Z","timestamp":1761284913000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1369527418300596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":77,"alternative-id":["S1369527418300596"],"URL":"https:\/\/doi.org\/10.1016\/j.mib.2018.11.010","relation":{},"ISSN":["1369-5274"],"issn-type":[{"value":"1369-5274","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Modulation of host cell metabolism by T4SS-encoding intracellular pathogens","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mib.2018.11.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}