{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:18:48Z","timestamp":1792459128070,"version":"4.5.0"},"reference-count":113,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2016\/23618-8"],"award-info":[{"award-number":["2016\/23618-8"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["RED-00012-14"],"award-info":[{"award-number":["RED-00012-14"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI079293"],"award-info":[{"award-number":["R01AI079293"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS098747"],"award-info":[{"award-number":["R01NS098747"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21AI131632"],"award-info":[{"award-number":["R21AI131632"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R0AI116577-02"],"award-info":[{"award-number":["R0AI116577-02"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["465293\/2014-0"],"award-info":[{"award-number":["465293\/2014-0"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Microbiology"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.mib.2019.08.002","type":"journal-article","created":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T23:09:32Z","timestamp":1568848172000},"page":"139-150","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Monocyte-derived dendritic cells in malaria"],"prefix":"10.1016","volume":"52","author":[{"given":"Isabella C","family":"Hirako","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia A","family":"Assis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Galv\u00e3o-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D","family":"Luster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lis RV","family":"Antonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo T","family":"Gazzinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mib.2019.08.002_bib0005","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1146\/annurev-immunol-032713-120220","article-title":"Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease","volume":"32","author":"Crompton","year":"2014","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0010","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/nri3742","article-title":"Innate sensing of malaria parasites","volume":"14","author":"Gazzinelli","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-immunol-100311-102839","article-title":"Decisions about dendritic cells: past, present, and future","volume":"30","author":"Steinman","year":"2012","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0020","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.immuni.2014.06.013","article-title":"Origin and functions of tissue macrophages","volume":"41","author":"Epelman","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_bib0025","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.immuni.2014.06.008","article-title":"Macrophage activation and polarization: nomenclature and experimental guidelines","volume":"41","author":"Murray","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_bib0030","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/ni.3341","article-title":"The development and maintenance of resident macrophages","volume":"17","author":"Perdiguero","year":"2016","journal-title":"Nat Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0035","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev.immunol.021908.132532","article-title":"Alternative activation of macrophages: an immunologic functional perspective","volume":"27","author":"Martinez","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0040","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1038\/nm.3189","article-title":"Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection","volume":"19","author":"Grainger","year":"2013","journal-title":"Nat Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0045","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/ni.3734","article-title":"Vitamin A mediates conversion of monocyte-derived macrophages into tissue-resident macrophages during alternative activation","volume":"18","author":"Gundra","year":"2017","journal-title":"Nat Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0050","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.immuni.2016.02.024","article-title":"Tissue-resident macrophage ontogeny and homeostasis","volume":"44","author":"Ginhoux","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_bib0055","first-page":"844","article-title":"Specialized role of migratory dendritic cells in peripheral tolerance induction","volume":"123","author":"Idoyaga","year":"2013","journal-title":"J Clin Invest"},{"key":"10.1016\/j.mib.2019.08.002_bib0060","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1084\/jem.180.1.83","article-title":"Proliferating dendritic cell progenitors in human blood","volume":"180","author":"Romani","year":"1994","journal-title":"J Exp Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0065","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1084\/jem.179.4.1109","article-title":"Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte\/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha","volume":"179","author":"Sallusto","year":"1994","journal-title":"J Exp Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0070","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.immuni.2007.01.017","article-title":"Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania","volume":"26","author":"Leon","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_bib0075","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/ni.1707","article-title":"Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses","volume":"10","author":"Nakano","year":"2009","journal-title":"Nat Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0080","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S1074-7613(03)00171-7","article-title":"TNF\/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection","volume":"19","author":"Serbina","year":"2003","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_bib0085","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.immuni.2010.03.017","article-title":"E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis","volume":"32","author":"Siddiqui","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_sbref0090","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.cell.2010.09.039","article-title":"Microbial stimulation fully differentiates monocytes to DC-SIGN\/CD209(+) dendritic cells for immune T cell areas","volume":"143","author":"Cheong","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.mib.2019.08.002_bib0095","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.immuni.2012.03.026","article-title":"NK cell-derived interferon-gamma orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection","volume":"36","author":"Goldszmid","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_sbref0100","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms13277","article-title":"Splenic differentiation and emergence of CCR5(+)CXCL9(+)CXCL10(+) monocyte-derived dendritic cells in the brain during cerebral malaria","volume":"7","author":"Hirako","year":"2016","journal-title":"Nat Commun"},{"key":"10.1016\/j.mib.2019.08.002_bib0105","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/2926436","article-title":"Dendritic cells and their multiple roles during malaria infection","volume":"2016","author":"Amorim","year":"2016","journal-title":"J Immunol Res"},{"key":"10.1016\/j.mib.2019.08.002_bib0110","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1038\/nrmicro1988","article-title":"What really happens to dendritic cells during malaria?","volume":"6","author":"Wykes","year":"2008","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.mib.2019.08.002_bib0115","doi-asserted-by":"crossref","first-page":"5173","DOI":"10.1128\/IAI.69.8.5173-5176.2001","article-title":"Dendritic cells can initiate protective immune responses against malaria","volume":"69","author":"Bruna-Romero","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2019.08.002_bib0120","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1038\/nm1628","article-title":"CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes","volume":"13","author":"Chakravarty","year":"2007","journal-title":"Nat Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004637","article-title":"Lymph-node resident CD8alpha+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses","volume":"11","author":"Radtke","year":"2015","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_sbref0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004598","article-title":"In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria","volume":"11","author":"Borges da Silva","year":"2015","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0135","doi-asserted-by":"crossref","first-page":"2970","DOI":"10.1002\/1521-4141(2001010)31:10<2970::AID-IMMU2970>3.0.CO;2-S","article-title":"Direct activation of dendritic cells by the malaria parasite, Plasmodium chabaudi chabaudi","volume":"31","author":"Seixas","year":"2001","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0140","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1128\/IAI.72.7.4233-4239.2004","article-title":"Response of the splenic dendritic cell population to malaria infection","volume":"72","author":"Leisewitz","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2019.08.002_bib0145","doi-asserted-by":"crossref","first-page":"441","DOI":"10.4049\/jimmunol.176.1.441","article-title":"Interaction of mouse dendritic cells and malaria-infected erythrocytes: uptake, maturation, and antigen presentation","volume":"176","author":"Ing","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0150","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0166-6851(96)02763-6","article-title":"Hemoglobin catabolism and iron utilization by malaria parasites","volume":"83","author":"Rosenthal","year":"1996","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.mib.2019.08.002_bib0155","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/abca067d-b82b-4de6-93c5-0fcc38e3df05","article-title":"Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases","volume":"5","author":"Shio","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0006510","article-title":"Malarial hemozoin is a Nalp3 inflammasome activating danger signal","volume":"4","author":"Dostert","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2019.08.002_bib0165","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.celrep.2013.12.014","article-title":"Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria","volume":"6","author":"Kalantari","year":"2014","journal-title":"Cell Rep"},{"key":"10.1016\/j.mib.2019.08.002_bib0170","doi-asserted-by":"crossref","first-page":"3689","DOI":"10.1073\/pnas.1015406108","article-title":"Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria","volume":"108","author":"Franklin","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2019.08.002_bib0175","first-page":"E511","article-title":"Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality","volume":"111","author":"Wu","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2019.08.002_bib0180","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1073\/pnas.0608745104","article-title":"Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9","volume":"104","author":"Parroche","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2019.08.002_bib0185","doi-asserted-by":"crossref","first-page":"5789","DOI":"10.1073\/pnas.0809742106","article-title":"Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function","volume":"106","author":"Franklin","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2019.08.002_bib0190","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.micinf.2007.03.007","article-title":"MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria","volume":"9","author":"Franklin","year":"2007","journal-title":"Microbes Infect"},{"key":"10.1016\/j.mib.2019.08.002_bib0195","doi-asserted-by":"crossref","first-page":"e01605","DOI":"10.1128\/mBio.01605-15","article-title":"DNA-containing immunocomplexes promote inflammasome assembly and release of pyrogenic cytokines by CD14+ CD16+ CD64high CD32low inflammatory monocytes from malaria patients","volume":"6","author":"Hirako","year":"2015","journal-title":"mBio"},{"key":"10.1016\/j.mib.2019.08.002_bib0200","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.immuni.2011.05.016","article-title":"Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome","volume":"35","author":"Sharma","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_bib0205","doi-asserted-by":"crossref","first-page":"768","DOI":"10.4049\/jimmunol.1701048","article-title":"Cyclic GMP-AMP synthase is the cytosolic sensor of Plasmodium falciparum genomic DNA and activates type I IFN in malaria","volume":"200","author":"Gallego-Marin","year":"2018","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0210","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.4049\/jimmunol.155.5.2545","article-title":"IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-gamma and TNF-alpha and occurs via a nitric oxide-dependent mechanism","volume":"155","author":"Stevenson","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0215","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/nri1311","article-title":"Innate immunity to malaria","volume":"4","author":"Stevenson","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0220","doi-asserted-by":"crossref","first-page":"5160","DOI":"10.4049\/jimmunol.1300462","article-title":"IFN-gamma-induced priming maintains long-term strain-transcending immunity against blood-stage Plasmodium chabaudi malaria","volume":"191","author":"da Silva","year":"2013","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0225","doi-asserted-by":"crossref","first-page":"5073","DOI":"10.4049\/jimmunol.1102143","article-title":"TLR9 and MyD88 are crucial for the development of protective immunity to malaria","volume":"188","author":"Gowda","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0230","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1086\/522865","article-title":"Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host","volume":"196","author":"Griffith","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.mib.2019.08.002_bib0235","doi-asserted-by":"crossref","first-page":"3990","DOI":"10.4049\/jimmunol.180.6.3990","article-title":"Sporozoite-mediated hepatocyte wounding limits Plasmodium parasite development via MyD88-mediated NF-kappa B activation and inducible NO synthase expression","volume":"180","author":"Torgler","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0240","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.micinf.2008.07.024","article-title":"MyD88\/IL-18-dependent pathways rather than TLRs control early parasitaemia in non-lethal Plasmodium yoelii infection","volume":"10","author":"Cramer","year":"2008","journal-title":"Microbes Infect"},{"key":"10.1016\/j.mib.2019.08.002_bib0245","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.4049\/jimmunol.168.3.1348","article-title":"IL-12 is required for antibody-mediated protective immunity against blood-stage Plasmodium chabaudi AS malaria infection in mice","volume":"168","author":"Su","year":"2002","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0250","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.0030096","article-title":"Plasmodium strain determines dendritic cell function essential for survival from malaria","volume":"3","author":"Wykes","year":"2007","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0255","doi-asserted-by":"crossref","first-page":"5921","DOI":"10.4049\/jimmunol.174.10.5921","article-title":"Cutting edge: the acquisition of TLR tolerance during malaria infection impacts T cell activation","volume":"174","author":"Perry","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0260","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003885","article-title":"Malaria-induced NLRP12\/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection","volume":"10","author":"Ataide","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0265","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1182\/blood.V74.7.2527.2527","article-title":"Identification and characterization of a novel monocyte subpopulation in human peripheral blood","volume":"74","author":"Passlick","year":"1989","journal-title":"Blood"},{"key":"10.1016\/j.mib.2019.08.002_bib0270","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/0167-5699(96)10029-3","article-title":"Heterogeneity of human blood monocytes: the CD14+ CD16+ subpopulation","volume":"17","author":"Ziegler-Heitbrock","year":"1996","journal-title":"Immunol Today"},{"key":"10.1016\/j.mib.2019.08.002_sbref0275","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.immuni.2010.08.012","article-title":"Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors","volume":"33","author":"Cros","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.mib.2019.08.002_bib0280","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/s12916-015-0391-7","article-title":"CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so","volume":"13","author":"Zhou","year":"2015","journal-title":"BMC Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0285","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.95352","article-title":"Monocyte dysregulation and systemic inflammation during pediatric falciparum malaria","volume":"2","author":"Dobbs","year":"2017","journal-title":"JCI Insight"},{"key":"10.1016\/j.mib.2019.08.002_bib0290","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1182\/blood-2009-07-235028","article-title":"Comparison of gene expression profiles between human and mouse monocyte subsets","volume":"115","author":"Ingersoll","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.mib.2019.08.002_bib0295","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.humimm.2012.08.002","article-title":"Myeloid blood dendritic cells and monocyte-derived dendritic cells differ in their endocytosing capability","volume":"73","author":"Andersson","year":"2012","journal-title":"Hum Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0300","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1182\/blood.V100.8.2858","article-title":"Myeloid blood CD11c(+) dendritic cells and monocyte-derived dendritic cells differ in their ability to stimulate T lymphocytes","volume":"100","author":"Osugi","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.mib.2019.08.002_sbref0305","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004393","article-title":"The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria","volume":"10","author":"Antonelli","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0310","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1016\/j.celrep.2015.11.055","article-title":"Type I interferon transcriptional signature in neutrophils and low-density granulocytes are associated with tissue damage in malaria","volume":"13","author":"Rocha","year":"2015","journal-title":"Cell Rep"},{"key":"10.1016\/j.mib.2019.08.002_bib0315","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1084\/jem.182.2.409","article-title":"Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages","volume":"182","author":"Bouharoun-Tayoun","year":"1995","journal-title":"J Exp Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0320","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/1741-7015-12-108","article-title":"Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria","volume":"12","author":"Osier","year":"2014","journal-title":"BMC Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0325","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001710","article-title":"Neutrophil paralysis in Plasmodium vivax malaria","volume":"6","author":"Leoratti","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.mib.2019.08.002_bib0330","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0952-7915(02)00368-0","article-title":"Malaria, monocytes, macrophages and myeloid dendritic cells: sticking of infected erythrocytes switches off host cells","volume":"14","author":"Urban","year":"2002","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0335","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.pt.2012.10.002","article-title":"Monocytes and macrophages in malaria: protection or pathology?","volume":"29","author":"Chua","year":"2013","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.mib.2019.08.002_bib0340","doi-asserted-by":"crossref","first-page":"6700","DOI":"10.1128\/IAI.00861-06","article-title":"The frequency of BDCA3-positive dendritic cells is increased in the peripheral circulation of Kenyan children with severe malaria","volume":"74","author":"Urban","year":"2006","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2019.08.002_bib0345","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/nm.3197","article-title":"Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection","volume":"19","author":"Guermonprez","year":"2013","journal-title":"Nat Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0350","doi-asserted-by":"crossref","first-page":"4763","DOI":"10.1128\/IAI.00578-10","article-title":"CD4+ CD25+ Foxp3+ regulatory T cells, dendritic cells, and circulating cytokines in uncomplicated malaria: do different parasite species elicit similar host responses?","volume":"78","author":"Goncalves","year":"2010","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2019.08.002_sbref0355","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1002\/eji.200838186","article-title":"Plasmodium vivax parasites alter the balance of myeloid and plasmacytoid dendritic cells and the induction of regulatory T cells","volume":"38","author":"Jangpatarapongsa","year":"2008","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0360","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1084\/jem.20121972","article-title":"Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria","volume":"210","author":"Pinzon-Charry","year":"2013","journal-title":"J Exp Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0365","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-02096-2","article-title":"Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation","volume":"7","author":"Loughland","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.mib.2019.08.002_sbref0370","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1093\/infdis\/jiy555","article-title":"Plasmodium falciparum activates CD16+ dendritic cells to produce tumor necrosis factor and interleukin-10 in subpatent malaria","volume":"219","author":"Loughland","year":"2019","journal-title":"J Infect Dis"},{"key":"10.1016\/j.mib.2019.08.002_bib0375","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00986-16","article-title":"Early immune regulatory changes in a primary controlled human Plasmodium vivax infection: CD1c(+) myeloid dendritic cell maturation arrest, induction of the kynurenine pathway, and regulatory T cell activation","volume":"85","author":"Woodberry","year":"2017","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2019.08.002_bib0380","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1186\/s12936-016-1382-7","article-title":"Characterization of blood dendritic and regulatory T cells in asymptomatic adults with sub-microscopic Plasmodium falciparum or Plasmodium vivax infection","volume":"15","author":"Kho","year":"2016","journal-title":"Malar J"},{"key":"10.1016\/j.mib.2019.08.002_bib0385","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/21900","article-title":"Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells","volume":"400","author":"Urban","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.mib.2019.08.002_bib0390","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/biof.5520240133","article-title":"Role of 4-hydroxynonenal in the hemozoin-mediated inhibition of differentiation of human monocytes to dendritic cells induced by GM-CSF\/IL-4","volume":"24","author":"Skorokhod","year":"2005","journal-title":"Biofactors"},{"key":"10.1016\/j.mib.2019.08.002_bib0395","doi-asserted-by":"crossref","first-page":"4066","DOI":"10.4049\/jimmunol.173.6.4066","article-title":"Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells: a peroxisome proliferator-activated receptor-gamma-mediated effect","volume":"173","author":"Skorokhod","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_sbref0400","doi-asserted-by":"crossref","first-page":"5522","DOI":"10.1182\/blood-2009-04-217489","article-title":"Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria","volume":"114","author":"Sponaas","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.mib.2019.08.002_sbref0405","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004236","article-title":"Real-time imaging reveals the dynamics of leukocyte behaviour during experimental cerebral malaria pathogenesis","volume":"10","author":"Pai","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0410","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0124080","article-title":"Specific depletion of Ly6C(hi) inflammatory monocytes prevents immunopathology in experimental cerebral malaria","volume":"10","author":"Schumak","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2019.08.002_sbref0415","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.98911","article-title":"CXCL10 stabilizes T cell-brain endothelial cell adhesion leading to the induction of cerebral malaria","volume":"3","author":"Sorensen","year":"2018","journal-title":"JCI Insight"},{"key":"10.1016\/j.mib.2019.08.002_sbref0420","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1016\/j.celrep.2018.11.059","article-title":"Organ-specific fate, recruitment, and refilling dynamics of tissue-resident macrophages during blood-stage malaria","volume":"25","author":"Lai","year":"2018","journal-title":"Cell Rep"},{"key":"10.1016\/j.mib.2019.08.002_sbref0425","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/s41385-018-0093-5","article-title":"The emergence of pathogenic TNF\/iNOS producing dendritic cells (Tip-DCs) in a malaria model of acute respiratory distress syndrome (ARDS) is dependent on CCR4","volume":"12","author":"Galvao-Filho","year":"2019","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0430","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002254","article-title":"Nrf2, a PPARgamma alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria","volume":"7","author":"Olagnier","year":"2011","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0435","doi-asserted-by":"crossref","first-page":"19517","DOI":"10.1074\/jbc.M116.746594","article-title":"Cannabinoid receptor 2 modulates susceptibility to experimental cerebral malaria through a CCL17-dependent mechanism","volume":"291","author":"Alferink","year":"2016","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mib.2019.08.002_sbref0440","doi-asserted-by":"crossref","first-page":"6033","DOI":"10.4049\/jimmunol.178.10.6033","article-title":"Cutting edge: conventional dendritic cells are the critical APC required for the induction of experimental cerebral malaria","volume":"178","author":"deWalick","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_sbref0445","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1189\/jlb.4HI0315-130RRR","article-title":"Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes","volume":"99","author":"Lagasse","year":"2016","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.mib.2019.08.002_bib0450","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006479","article-title":"Divergent roles for Ly6C+CCR2+CX3CR1+ inflammatory monocytes during primary or secondary infection of the skin with the intra-phagosomal pathogen Leishmania major","volume":"13","author":"Romano","year":"2017","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0455","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1086\/510756","article-title":"Lung injury in vivax malaria: pathophysiological evidence for pulmonary vascular sequestration and posttreatment alveolar-capillary inflammation","volume":"195","author":"Anstey","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.mib.2019.08.002_bib0460","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1086\/497697","article-title":"Lung injury in uncomplicated and severe falciparum malaria: a longitudinal study in Papua, Indonesia","volume":"192","author":"Maguire","year":"2005","journal-title":"J Infect Dis"},{"key":"10.1016\/j.mib.2019.08.002_bib0465","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1097\/CCM.0b013e31827466d2","article-title":"Fluid resuscitation of adults with severe falciparum malaria: effects on acid-base status, renal function, and extravascular lung water","volume":"41","author":"Hanson","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0470","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4103\/0972-9062.117493","article-title":"Acute pancreatitis and acute respiratory distress syndrome complicating Plasmodium vivax malaria","volume":"50","author":"Atam","year":"2013","journal-title":"J Vector Borne Dis"},{"key":"10.1016\/j.mib.2019.08.002_bib0475","doi-asserted-by":"crossref","first-page":"551","DOI":"10.3347\/kjp.2013.51.5.551","article-title":"A case of vivax malaria complicated by adult respiratory distress syndrome and successful management with extracorporeal membrane oxygenation","volume":"51","author":"Lee","year":"2013","journal-title":"Korean J Parasitol"},{"key":"10.1016\/j.mib.2019.08.002_bib0480","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1165\/rcmb.2012-0450OC","article-title":"Hemozoin induces lung inflammation and correlates with malaria-associated acute respiratory distress syndrome","volume":"48","author":"Deroost","year":"2013","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.mib.2019.08.002_bib0485","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1164\/rccm.200905-0786OC","article-title":"Immunopathology and dexamethasone therapy in a new model for malaria-associated acute respiratory distress syndrome","volume":"181","author":"Van den Steen","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0490","doi-asserted-by":"crossref","first-page":"416","DOI":"10.3389\/fcimb.2017.00416","article-title":"Pathogenic CD8(+) T cells cause increased levels of VEGF-A in experimental malaria-associated acute respiratory distress syndrome, but therapeutic VEGFR inhibition is not effective","volume":"7","author":"Pham","year":"2017","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2019.08.002_bib0495","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.3389\/fimmu.2017.01199","article-title":"Plasmodium berghei NK65 in combination with IFN-gamma induces endothelial glucocorticoid resistance via sustained activation of p38 and JNK","volume":"8","author":"Zielinska","year":"2017","journal-title":"Front Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0500","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.ajpath.2012.08.010","article-title":"Cerebral malaria: we have come a long way","volume":"181","author":"Shikani","year":"2012","journal-title":"Am J Pathol"},{"key":"10.1016\/j.mib.2019.08.002_bib0505","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1203\/PDR.0b013e3181eee738","article-title":"Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome","volume":"68","author":"Idro","year":"2010","journal-title":"Pediatr Res"},{"key":"10.1016\/j.mib.2019.08.002_bib0510","first-page":"91","article-title":"Anti-TNF therapy inhibits fever in cerebral malaria","volume":"86","author":"Kwiatkowski","year":"1993","journal-title":"Q J Med"},{"key":"10.1016\/j.mib.2019.08.002_bib0515","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1126\/science.3306918","article-title":"Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria","volume":"237","author":"Grau","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.mib.2019.08.002_bib0520","doi-asserted-by":"crossref","first-page":"5572","DOI":"10.1073\/pnas.86.14.5572","article-title":"Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor","volume":"86","author":"Grau","year":"1989","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2019.08.002_bib0525","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1172\/JCI70698","article-title":"Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity","volume":"124","author":"Haque","year":"2014","journal-title":"J Clin Invest"},{"key":"10.1016\/j.mib.2019.08.002_bib0530","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.4049\/jimmunol.1201171","article-title":"Cutting edge: Clec9A+ dendritic cells mediate the development of experimental cerebral malaria","volume":"189","author":"Piva","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0535","doi-asserted-by":"crossref","first-page":"3947","DOI":"10.1128\/IAI.01337-10","article-title":"Prevention of experimental cerebral malaria by Flt3 ligand during infection with Plasmodium berghei ANKA","volume":"79","author":"Tamura","year":"2011","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2019.08.002_sbref0540","doi-asserted-by":"crossref","first-page":"4814","DOI":"10.1073\/pnas.0801544105","article-title":"Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria","volume":"105","author":"Campanella","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.mib.2019.08.002_bib0545","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000369","article-title":"IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection","volume":"5","author":"Nie","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0550","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005507","article-title":"Promotion of expansion and differentiation of hematopoietic stem cells by interleukin-27 into myeloid progenitors to control infection in emergency myelopoiesis","volume":"12","author":"Furusawa","year":"2016","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0555","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003406","article-title":"Extramedullary myelopoiesis in malaria depends on mobilization of myeloid-restricted progenitors by IFN-gamma induced chemokines","volume":"9","author":"Belyaev","year":"2013","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2019.08.002_bib0560","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/ni.1869","article-title":"Induction of an IL7-R(+)c-Kit(hi) myelolymphoid progenitor critically dependent on IFN-gamma signaling during acute malaria","volume":"11","author":"Belyaev","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.mib.2019.08.002_bib0565","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.immuni.2008.05.019","article-title":"Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii","volume":"29","author":"Dunay","year":"2008","journal-title":"Immunity"}],"container-title":["Current Opinion in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1369527419300189?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1369527419300189?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T17:09:55Z","timestamp":1778605795000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1369527419300189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":113,"alternative-id":["S1369527419300189"],"URL":"https:\/\/doi.org\/10.1016\/j.mib.2019.08.002","relation":{},"ISSN":["1369-5274"],"issn-type":[{"value":"1369-5274","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Monocyte-derived dendritic cells in malaria","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mib.2019.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}