{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:16:09Z","timestamp":1786994169909,"version":"build-2736575974"},"reference-count":85,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009053","name":"DBT\/Wellcome Trust India Alliance","doi-asserted-by":"publisher","award":["IA\/S\/21\/2\/505907"],"award-info":[{"award-number":["IA\/S\/21\/2\/505907"]}],"id":[{"id":"10.13039\/501100009053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmn.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Microbiology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.mib.2025.102609","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T11:18:30Z","timestamp":1744975110000},"page":"102609","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Long-chain fatty acids as nutrients for Gram-negative bacteria: stress, proliferation, and virulence"],"prefix":"10.1016","volume":"85","author":[{"given":"Megha","family":"Shrivastava","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deeptodeep","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9156-4543","authenticated-orcid":false,"given":"Rachna","family":"Chaba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mib.2025.102609_sbref1","doi-asserted-by":"crossref","DOI":"10.3390\/biom12081019","article-title":"Degradation of exogenous fatty acids in Escherichia coli","volume":"12","author":"Pavoncello","year":"2022","journal-title":"Biomolecules"},{"key":"10.1016\/j.mib.2025.102609_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.mib.2023.102402","article-title":"Matching the \u03b2-oxidation gene repertoire with the wide diversity of fatty acids","volume":"77","author":"Schiaffi","year":"2024","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens9080614","article-title":"Modulation of host lipid pathways by pathogenic intracellular bacteria","volume":"9","author":"Allen","year":"2020","journal-title":"Pathogens"},{"key":"10.1016\/j.mib.2025.102609_bib4","doi-asserted-by":"crossref","first-page":"e01725","DOI":"10.1128\/mBio.01725-15","article-title":"Corynebacterium accolens releases antipneumococcal free fatty acids from human nostril and skin surface triacylglycerols","volume":"7","author":"Bomar","year":"2016","journal-title":"mBio"},{"key":"10.1016\/j.mib.2025.102609_bib5","article-title":"Antimicrobial activity of host-derived lipids","volume":"9","author":"Fischer","year":"2020","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.mib.2025.102609_sbref6","doi-asserted-by":"crossref","first-page":"5313","DOI":"10.1128\/IAI.01807-06","article-title":"In vivo evidence of Pseudomonas aeruginosa nutrient acquisition and pathogenesis in the lungs of cystic fibrosis patients","volume":"75","author":"Son","year":"2007","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2025.102609_sbref7","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.928503","article-title":"Long chain fatty acids and virulence repression in intestinal bacterial pathogens","volume":"12","author":"Mitchell","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib8","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/skab117","article-title":"Short-, medium-, and long-chain fatty acid profiles and signaling is responsive to dietary phytase and lactic acid treatment of cereals along the gastrointestinal tract of growing pigs","volume":"99","author":"Metzler-Zebeli","year":"2021","journal-title":"J Anim Sci"},{"key":"10.1016\/j.mib.2025.102609_bib9","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1128\/JB.00622-15","article-title":"Acinetobacter baumannii is dependent on the type II secretion system and its substrate LipA for lipid utilization and in vivo fitness","volume":"198","author":"Johnson","year":"2015","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_bib10","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.ijmm.2016.09.006","article-title":"The secretome of Acinetobacter baumannii ATCC 17978 type II secretion system reveals a novel plasmid encoded phospholipase that could be implicated in lung colonization","volume":"306","author":"Elhosseiny","year":"2016","journal-title":"Int J Med Microbiol"},{"key":"10.1016\/j.mib.2025.102609_sbref11","doi-asserted-by":"crossref","DOI":"10.1128\/mmbr.00126-24","article-title":"Bacterial acquisition of host fatty acids has far-reaching implications on virulence","volume":"88","author":"Waters","year":"2024","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1016\/j.mib.2025.102609_sbref12","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.tim.2021.06.002","article-title":"Bacterial adaptation strategies to host-derived fatty acids","volume":"30","author":"Kengmo Tchoupa","year":"2022","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.mib.2025.102609_sbref13","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.tim.2020.03.014","article-title":"Fatty acids as antibiofilm and antivirulence agents","volume":"28","author":"Kumar","year":"2020","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2021.101093","article-title":"Antibacterial fatty acids: an update of possible mechanisms of action and implications in the development of the next-generation of antibacterial agents","volume":"82","author":"Casillas-Vargas","year":"2021","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.mib.2025.102609_bib15","doi-asserted-by":"crossref","DOI":"10.1093\/femsre\/fuad037","article-title":"Anti-infective activities of long-chain fatty acids against foodborne pathogens","volume":"47","author":"Borreby","year":"2023","journal-title":"FEMS Microbiol Rev"},{"key":"10.1016\/j.mib.2025.102609_sbref16","doi-asserted-by":"crossref","first-page":"20086","DOI":"10.1074\/jbc.M117.806240","article-title":"A genome-wide screen in Escherichia coli reveals that ubiquinone is a key antioxidant for metabolism of long-chain fatty acids","volume":"292","author":"Agrawal","year":"2017","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mib.2025.102609_sbref17","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s00253-013-5327-6","article-title":"Reduction of hydrogen peroxide stress derived from fatty acid \u03b2-oxidation improves fatty acid utilization in Escherichia coli","volume":"98","author":"Doi","year":"2014","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.mib.2025.102609_sbref18","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s00294-021-01178-z","article-title":"Revisiting long-chain fatty acid metabolism in Escherichia coli: integration with stress responses","volume":"67","author":"Jaswal","year":"2021","journal-title":"Curr Genet"},{"key":"10.1016\/j.mib.2025.102609_sbref19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1009081","article-title":"Metabolism of long-chain fatty acids affects disulfide bond formation in Escherichia coli and activates envelope stress response pathways as a combat strategy","volume":"16","author":"Jaswal","year":"2020","journal-title":"PLoS Genet"},{"key":"10.1016\/j.mib.2025.102609_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0309988","article-title":"Evidence for endogenous hydrogen peroxide production by E. coli fatty acyl-CoA dehydrogenase","volume":"19","author":"Sirithanakorn","year":"2024","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2025.102609_bib21","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1128\/JB.188.2.599-608.2006","article-title":"The \u03b2-oxidation systems of Escherichia coli and Salmonella enterica are not functionally equivalent","volume":"188","author":"Iram","year":"2006","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_bib22","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1046\/j.1365-2958.2003.03341.x","article-title":"A new Escherichia coli metabolic competency: growth on fatty acids by a novel anaerobic \u03b2-oxidation pathway","volume":"47","author":"Campbell","year":"2003","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib23","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1042\/BCJ20190314","article-title":"Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic \u03b2-oxidation trifunctional enzyme complexes","volume":"476","author":"Sah-Teli","year":"2019","journal-title":"Biochem J"},{"key":"10.1016\/j.mib.2025.102609_bib24","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.str.2023.04.011","article-title":"Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial \u03b2-oxidation trifunctional enzymes","volume":"31","author":"Sah-Teli","year":"2023","journal-title":"Structure"},{"key":"10.1016\/j.mib.2025.102609_bib25","doi-asserted-by":"crossref","first-page":"37324","DOI":"10.1074\/jbc.M405233200","article-title":"The Escherichia coli fadK (ydiD) gene encodes an anerobically regulated short chain acyl-CoA synthetase","volume":"279","author":"Morgan-Kiss","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mib.2025.102609_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/a55051c6-25dc-4548-912e-bf339830668e","article-title":"Multiple FadD acyl-CoA synthetases contribute to differential fatty acid degradation and virulence in Pseudomonas aeruginosa","volume":"5","author":"Kang","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2025.102609_bib27","article-title":"Blocking phosphatidylcholine utilization in Pseudomonas aeruginosa, via mutagenesis of fatty acid, glycerol and choline degradation pathways, confirms the importance of this nutrient source in vivo","volume":"9","author":"Sun","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2025.102609_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0064554","article-title":"Elucidating the Pseudomonas aeruginosa fatty acid degradation pathway: identification of additional fatty acyl-CoA synthetase homologues","volume":"8","author":"Zarzycki-Siek","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2025.102609_bib29","doi-asserted-by":"crossref","first-page":"5967","DOI":"10.1093\/nar\/gkaa377","article-title":"PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids","volume":"48","author":"Pan","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.mib.2025.102609_bib30","article-title":"Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity","volume":"16","author":"Wang","year":"2025","journal-title":"Nat Commun"},{"key":"10.1016\/j.mib.2025.102609_bib31","doi-asserted-by":"crossref","first-page":"8044","DOI":"10.1073\/pnas.1920753117","article-title":"Switching fatty acid metabolism by an RNA-controlled feed forward loop","volume":"117","author":"Huber","year":"2020","journal-title":"Proc Natl Acad Sci USA"},{"issue":"Pt 6","key":"10.1016\/j.mib.2025.102609_bib32","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1099\/mic.0.2008\/018135-0","article-title":"The Pseudomonas aeruginosa PsrA responds to long-chain fatty acid signals to regulate the fadBA5 \u03b2-oxidation operon","volume":"154","author":"Kang","year":"2008","journal-title":"Microbiology"},{"key":"10.1016\/j.mib.2025.102609_bib33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0189331","article-title":"PsrA controls the synthesis of the Pseudomonas aeruginosa quinolone signal via repression of the FadE homolog, PA0506","volume":"12","author":"Wells","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2025.102609_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104443","article-title":"Vibrio cholerae VC1741 (PsrA) enhances the colonization of the pathogen in infant mice intestines in the presence of the long-chain fatty acid, oleic acid","volume":"147","author":"Yang","year":"2020","journal-title":"Microb Pathog"},{"key":"10.1016\/j.mib.2025.102609_bib35","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1128\/JB.01175-08","article-title":"Comparative genomics of regulation of fatty acid and branched-chain amino acid utilization in proteobacteria","volume":"191","author":"Kazakov","year":"2009","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_bib36","doi-asserted-by":"crossref","first-page":"12875","DOI":"10.1073\/pnas.1109379108","article-title":"Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon","volume":"108","author":"Gogol","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.mib.2025.102609_bib37","first-page":"835","article-title":"The structure of fadL mRNA and its interactions with RybB sRNA","volume":"63","author":"Groszewska","year":"2016","journal-title":"Acta Biochim Pol"},{"key":"10.1016\/j.mib.2025.102609_bib38","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.cell.2016.09.004","article-title":"sRNA-mediated control of transcription termination in E. coli","volume":"167","author":"Sedlyarova","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.mib.2025.102609_bib39","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/nrmicro1788","article-title":"Salmonellae interplay with host cells","volume":"6","author":"Haraga","year":"2008","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib40","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1128\/JB.183.9.2733-2745.2001","article-title":"Roles of hilC and hilD in regulation of hilA expression in Salmonella enterica serovar Typhimurium","volume":"183","author":"Lucas","year":"2001","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_bib41","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1128\/JB.182.7.1872-1882.2000","article-title":"Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar typhimurium","volume":"182","author":"Lucas","year":"2000","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_bib42","doi-asserted-by":"crossref","first-page":"e02170","DOI":"10.1128\/mBio.02170-15","article-title":"Intestinal long-chain fatty acids act as a direct signal to modulate expression of the Salmonella pathogenicity island 1 type III secretion system","volume":"7","author":"Golubeva","year":"2016","journal-title":"mBio"},{"key":"10.1016\/j.mib.2025.102609_bib43","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1073\/pnas.92.3.669","article-title":"Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host","volume":"92","author":"Mahan","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.mib.2025.102609_bib44","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1574-6968.1998.tb13036.x","article-title":"A Salmonella typhimurium mutant unable to utilize fatty acids and citrate is avirulent and immunogenic in mice","volume":"163","author":"Utley","year":"1998","journal-title":"FEMS Microbiol Lett"},{"issue":"Pt 1","key":"10.1016\/j.mib.2025.102609_bib45","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1099\/13500872-145-1-15","article-title":"The medium-\/long-chain fatty acyl-CoA dehydrogenase (fadF) gene of Salmonella typhimurium is a phase 1 starvation-stress response (SSR) locus","volume":"145","author":"Spector","year":"1999","journal-title":"Microbiology"},{"key":"10.1016\/j.mib.2025.102609_sbref46","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1128\/IAI.73.4.2547-2549.2005","article-title":"Isocitrate lyase (AceA) is required for Salmonella persistence but not for acute lethal infection in mice","volume":"73","author":"Fang","year":"2005","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2025.102609_bib47","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1128\/IAI.74.4.2498-2502.2006","article-title":"Mutation of phosphotransacetylase but not isocitrate lyase reduces the virulence of Salmonella enterica serovar Typhimurium in mice","volume":"74","author":"Kim","year":"2006","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2025.102609_bib48","doi-asserted-by":"crossref","DOI":"10.1128\/iai.00184-22","article-title":"Fatty acid homeostasis tunes flagellar motility by activating phase 2 flagellin expression, contributing to Salmonella gut colonization","volume":"90","author":"Hoshino","year":"2022","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2025.102609_bib49","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003301","article-title":"Parallel exploitation of diverse host nutrients enhances Salmonella virulence","volume":"9","author":"Steeb","year":"2013","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2025.102609_bib50","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1080\/21505594.2016.1270493","article-title":"The infectious intracellular lifestyle of Salmonella enterica relies on the adaptation to nutritional conditions within the Salmonella-containing vacuole","volume":"8","author":"Diacovich","year":"2017","journal-title":"Virulence"},{"key":"10.1016\/j.mib.2025.102609_sbref51","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00776-19","article-title":"Salmonella enterica requires lipid metabolism genes to replicate in proinflammatory macrophages and mice","volume":"88","author":"Reens","year":"2019","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2025.102609_bib52","doi-asserted-by":"crossref","first-page":"7729","DOI":"10.1021\/acs.analchem.9b01010","article-title":"Single-cell and time-resolved profiling of intracellular Salmonella metabolism in primary human cells","volume":"91","author":"Xu","year":"2019","journal-title":"Anal Chem"},{"key":"10.1016\/j.mib.2025.102609_bib53","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/mmi.14844","article-title":"Lipid droplet accumulation occurs early following Salmonella infection and contributes to intracellular bacterial survival and replication","volume":"117","author":"Kiarely Souza","year":"2022","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib54","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.BAI-0023-2019","article-title":"Shigella pathogenesis: new insights through advanced methodologies","volume":"7","author":"Schnupf","year":"2019","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.mib.2025.102609_bib55","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00778-23","article-title":"Fatty acids abolish Shigella virulence by inhibiting its master regulator, VirF","volume":"11","author":"Trirocco","year":"2023","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.mib.2025.102609_bib56","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2256767","article-title":"Shigella flexneri utilizes intestinal signals to control its virulence","volume":"15","author":"Chowdhury","year":"2023","journal-title":"Gut Microbes"},{"key":"10.1016\/j.mib.2025.102609_bib57","doi-asserted-by":"crossref","first-page":"9929","DOI":"10.1073\/pnas.1406694111","article-title":"Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth","volume":"111","author":"Kentner","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.mib.2025.102609_sbref58","doi-asserted-by":"crossref","DOI":"10.1128\/jb.00320-23","article-title":"Shigella flexneri remodeling and consumption of host lipids during infection","volume":"205","author":"Ascari","year":"2023","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_bib59","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1021\/acsinfecdis.3c00210","article-title":"Shigella flexneri adapts to niche-specific stresses through modifications in cell envelope composition and decoration","volume":"9","author":"Ascari","year":"2023","journal-title":"ACS Infect Dis"},{"key":"10.1016\/j.mib.2025.102609_bib60","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004787","article-title":"Intestinal colonization dynamics of Vibrio cholerae","volume":"11","author":"Almagro-Moreno","year":"2015","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mib.2025.102609_bib61","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1128\/JB.02409-14","article-title":"Mechanism for inhibition of Vibrio cholerae ToxT activity by the unsaturated fatty acid components of bile","volume":"197","author":"Plecha","year":"2015","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_bib62","doi-asserted-by":"crossref","DOI":"10.1038\/s42003-019-0686-x","article-title":"Structural basis for virulence regulation in Vibrio cholerae by unsaturated fatty acid components of bile","volume":"2","author":"Cruite","year":"2019","journal-title":"Commun Biol"},{"key":"10.1016\/j.mib.2025.102609_bib63","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1128\/IAI.01435-06","article-title":"Effect of fatty acids and cholesterol present in bile on expression of virulence factors and motility of Vibrio cholerae","volume":"75","author":"Chatterjee","year":"2007","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2025.102609_bib64","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00762-16","article-title":"The fatty acid regulator FadR influences the expression of the virulence cascade in the El Tor biotype of Vibrio cholerae by modulating the levels of ToxT via two different mechanisms","volume":"199","author":"Kovacikova","year":"2017","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_sbref65","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/s41586-019-1453-3","article-title":"Cholera toxin promotes pathogen acquisition of host-derived nutrients","volume":"572","author":"Rivera-Chavez","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.mib.2025.102609_bib66","doi-asserted-by":"crossref","first-page":"4038","DOI":"10.1128\/JB.00129-08","article-title":"Pseudomonas aeruginosa twitching motility-mediated chemotaxis towards phospholipids and fatty acids: specificity and metabolic requirements","volume":"190","author":"Miller","year":"2008","journal-title":"J Bacteriol"},{"issue":"Pt 6","key":"10.1016\/j.mib.2025.102609_bib67","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1099\/mic.0.2007\/014506-0","article-title":"Virulence determinants from a cystic fibrosis isolate of Pseudomonas aeruginosa include isocitrate lyase","volume":"154","author":"Lindsey","year":"2008","journal-title":"Microbiology"},{"key":"10.1016\/j.mib.2025.102609_bib68","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1365-2958.2009.06757.x","article-title":"The long-chain fatty acid sensor, PsrA, modulates the expression of rpoS and the type III secretion exsCEBA operon in Pseudomonas aeruginosa","volume":"73","author":"Kang","year":"2009","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib69","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1093\/nar\/gkad059","article-title":"Regulatory and structural mechanisms of PvrA-mediated regulation of the PQS quorum-sensing system and PHA biosynthesis in Pseudomonas aeruginosa","volume":"51","author":"Pan","year":"2023","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.mib.2025.102609_bib70","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1424330","article-title":"Roles of transcriptional factor PsrA in the regulation of quorum sensing in Pseudomonas aeruginosa PAO1","volume":"15","author":"Kok","year":"2024","journal-title":"Front Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib71","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02056-18","article-title":"Identification of novel Acinetobacter baumannii host fatty acid stress adaptation strategies","volume":"10","author":"Jiang","year":"2019","journal-title":"mBio"},{"key":"10.1016\/j.mib.2025.102609_bib72","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0138360","article-title":"Acinetobacter baumannii virulence is mediated by the concerted action of three phospholipases D","volume":"10","author":"Stahl","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.mib.2025.102609_sbref73","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00928-21","article-title":"To make or take: bacterial lipid homeostasis during infection","volume":"12","author":"Adams","year":"2021","journal-title":"mBio"},{"key":"10.1016\/j.mib.2025.102609_bib74","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41564-017-0106-2","article-title":"Disulfide bond formation in prokaryotes","volume":"3","author":"Landeta","year":"2018","journal-title":"Nat Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib75","article-title":"An envelope stress response governs long-chain fatty acid metabolism via a small RNA to maintain redox homeostasis in Escherichia coli","author":"Shrivastava","year":"2024","journal-title":"bioRxiv"},{"key":"10.1016\/j.mib.2025.102609_bib76","doi-asserted-by":"crossref","DOI":"10.1002\/mbo3.635","article-title":"Exogenous fatty acids alter phospholipid composition, membrane permeability, capacity for biofilm formation, and antimicrobial peptide susceptibility in Klebsiella pneumoniae","volume":"8","author":"Hobby","year":"2019","journal-title":"Microbiologyopen"},{"key":"10.1016\/j.mib.2025.102609_bib77","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1128\/JB.01065-13","article-title":"ubiJ, a new gene required for aerobic growth and proliferation in macrophage, is involved in coenzyme Q biosynthesis in Escherichia coli and Salmonella enterica serovar Typhimurium","volume":"196","author":"Aussel","year":"2014","journal-title":"J Bacteriol"},{"key":"10.1016\/j.mib.2025.102609_bib78","doi-asserted-by":"crossref","first-page":"11937","DOI":"10.1074\/jbc.M117.789164","article-title":"The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ","volume":"292","author":"Loiseau","year":"2017","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mib.2025.102609_bib79","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1111\/j.1574-6976.2007.00081.x","article-title":"The role of Dsb proteins of Gram-negative bacteria in the process of pathogenesis","volume":"31","author":"Lasica","year":"2007","journal-title":"FEMS Microbiol Rev"},{"key":"10.1016\/j.mib.2025.102609_bib80","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1128\/iai.62.7.2662-2668.1994","article-title":"Comparison of the sensitivities of Salmonella typhimurium oxyR and katG mutants to killing by human neutrophils","volume":"62","author":"Papp-Szabo","year":"1994","journal-title":"Infect Immun"},{"key":"10.1016\/j.mib.2025.102609_bib81","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000496370","article-title":"Salmonella and reactive oxygen species: a love-hate relationship","volume":"11","author":"Rhen","year":"2019","journal-title":"J Innate Immun"},{"key":"10.1016\/j.mib.2025.102609_bib82","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2019.00313","article-title":"Maintaining integrity under stress: envelope stress response regulation of pathogenesis in Gram-negative bacteria","volume":"9","author":"Hews","year":"2019","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.mib.2025.102609_bib83","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1126\/science.1232467","article-title":"Host-derived nitrate boosts growth of E. coli in the inflamed gut","volume":"339","author":"Winter","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.mib.2025.102609_bib84","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.chom.2020.09.005","article-title":"Epithelial-derived reactive oxygen species enable AppBCX-mediated aerobic respiration of Escherichia coli during intestinal inflammation","volume":"28","author":"Chanin","year":"2020","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.mib.2025.102609_bib85","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.chom.2016.03.004","article-title":"Depletion of butyrate-producing clostridia from the gut microbiota drives an aerobic luminal expansion of Salmonella","volume":"19","author":"Rivera-Chavez","year":"2016","journal-title":"Cell host Microbe"}],"container-title":["Current Opinion in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1369527425000311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1369527425000311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T04:47:38Z","timestamp":1748839658000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1369527425000311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":85,"alternative-id":["S1369527425000311"],"URL":"https:\/\/doi.org\/10.1016\/j.mib.2025.102609","relation":{},"ISSN":["1369-5274"],"issn-type":[{"value":"1369-5274","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-chain fatty acids as nutrients for Gram-negative bacteria: stress, proliferation, and virulence","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mib.2025.102609","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102609"}}