{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:52:21Z","timestamp":1790815941725,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":7153,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1016\/j.micinf.2004.03.004","type":"journal-article","created":{"date-parts":[[2004,4,21]],"date-time":"2004-04-21T02:04:48Z","timestamp":1082513088000},"page":"657-665","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["A monoclonal antibody to glucosylceramide inhibits the growth of Fonsecaea pedrosoi and enhances the antifungal action of mouse macrophages"],"prefix":"10.1016","volume":"6","author":[{"given":"Leonardo","family":"Nimrichter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana","family":"Barreto-Bergter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo R.","family":"Mendon\u00e7a-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucimar F.","family":"Kneipp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana T.","family":"Mazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia","family":"Salve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra E.","family":"Farias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Wait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celuta S.","family":"Alviano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcio L.","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micinf.2004.03.004_BIB1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1034\/j.1600-0560.2003.00067.x","article-title":"An unusual dematiaceous fungal infection of the skin caused by Fonsecaea pedrosoi: a case report and review of the literature","volume":"30","author":"Hamza","year":"2003","journal-title":"J. Cutan. Pathol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB2","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1080\/02681219080000481","article-title":"Fine structure and cytochemistry of the interaction between Fonsecaea pedrosoi and mouse resident macrophages","volume":"28","author":"Farbiarz","year":"1990","journal-title":"J. Med. Vet. Mycol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB3","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1099\/00222615-20-3-299","article-title":"Role of the fungal cell wall in the granulomatous response of mice to the agents of chromomycosis","volume":"20","author":"Silva","year":"1985","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB4","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF01146200","article-title":"The in vitro susceptibility of Fonsecaea pedrosoi to activated macrophages","volume":"126","author":"Rozental","year":"1994","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micinf.2004.03.004_BIB5","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0733-8635(18)30593-X","article-title":"Chromoblastomycosis","volume":"7","author":"Milam","year":"1989","journal-title":"Dermatol. Clin."},{"key":"10.1016\/j.micinf.2004.03.004_BIB6","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1346-8138.1996.tb02671.x","article-title":"A case of chromomycosis with tumor-like growth","volume":"23","author":"Usuki","year":"1996","journal-title":"J. Dermatol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB7","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1067\/mjd.2001.112220","article-title":"Chromoblastomycosis: a review of 100\u00a0cases in the state of Rio Grande do Sul, Brazil","volume":"44","author":"Minotto","year":"2001","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1439-0507.2001.00613.x","article-title":"Chromoblastomycosis: clinical and mycologic experience of 51\u00a0cases","volume":"44","author":"Bonifaz","year":"2001","journal-title":"Mycoses"},{"key":"10.1016\/j.micinf.2004.03.004_BIB9","doi-asserted-by":"crossref","first-page":"61","DOI":"10.4269\/ajtmh.2000.63.61","article-title":"A case of chromomycosis treated by a combination of cryotherapy, shaving, oral 5-fluorocytosine, and oral amphotericin B","volume":"63","author":"Poirriez","year":"2000","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.micinf.2004.03.004_BIB10","first-page":"45","article-title":"Treatment of chromoblastomycosis due to Fonsecaea pedrosoi with low-dose terbinafine","volume":"66","author":"Sevigny","year":"2000","journal-title":"Cutis"},{"key":"10.1016\/j.micinf.2004.03.004_BIB11","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1046\/j.1439-0507.2000.00548.x","article-title":"Case report. A case of chromoblastomycosis effectively treated with terbinafine. Characteristics of chromoblastomycosis in the Kitasato region, Japan","volume":"43","author":"Tanuma","year":"2000","journal-title":"Mycoses"},{"key":"10.1016\/j.micinf.2004.03.004_BIB12","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/glycob\/12.4.251","article-title":"Characterization of glucosylceramides in Pseudallescheria boydii and their involvement in fungal differentiation","volume":"12","author":"Pinto","year":"2002","journal-title":"Glycobiology"},{"key":"10.1016\/j.micinf.2004.03.004_BIB13","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1590\/S0001-37652004000100007","article-title":"Structure and biological functions of fungal cerebrosides","volume":"76","author":"Barreto-Bergter","year":"2004","journal-title":"An. Acad. Bras. Cienc."},{"key":"10.1016\/j.micinf.2004.03.004_BIB14","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0014-5793(02)03067-3","article-title":"Disruption of the glucosylceramide biosynthetic pathway in Aspergillus nidulans and Aspergillus fumigatus by inhibitors of UDP-Glc:ceramide glucosyltransferase strongly affects spore germination, cell and hyphal growth","volume":"525","author":"Levery","year":"2002","journal-title":"FEBS Lett."},{"key":"10.1016\/j.micinf.2004.03.004_BIB15","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1517\/13543784.9.8.1787","article-title":"Antifungals targeted to sphingolipid synthesis: focus on inositol phosphorylceramide synthase","volume":"9","author":"Georgopapadakou","year":"2000","journal-title":"Expert Opin. Investig. Drugs"},{"key":"10.1016\/j.micinf.2004.03.004_BIB16","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/S0005-2760(97)00179-3","article-title":"Structural characterization of neutral glycosphingolipids from Fusarium species","volume":"1390","author":"Duarte","year":"1998","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.micinf.2004.03.004_BIB17","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/(SICI)1097-0231(20000415)14:7<551::AID-RCM909>3.0.CO;2-L","article-title":"Comparative analysis of ceramide structural modification found in fungal cerebrosides by electrospray tandem mass spectrometry with low energy collision-induced dissociation of Li+ adduct ions","volume":"14","author":"Levery","year":"2000","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.micinf.2004.03.004_BIB18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0009-3084(87)90012-0","article-title":"Cerebroside of the dimorphic human pathogen Candida albicans","volume":"43","author":"Matsubara","year":"1987","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.micinf.2004.03.004_BIB19","doi-asserted-by":"crossref","first-page":"7049","DOI":"10.1128\/IAI.68.12.7049-7060.2000","article-title":"Human antibodies against a purified glucosylceramide from Cryptococcus neoformans inhibit cell budding and fungal growth","volume":"68","author":"Rodrigues","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2004.03.004_BIB20","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0014-5793(04)00156-5","article-title":"Glucosylceramides in Colletotrichum gloeosporioides are involved in the differentiation of conidia into mycelial cells","volume":"561","author":"da Silva","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.micinf.2004.03.004_BIB21","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0022-2275(20)32388-9","article-title":"Dimorphic expression of cerebrosides in the mycopathogen Sporothrix schenckii","volume":"41","author":"Toledo","year":"2000","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.micinf.2004.03.004_BIB22","doi-asserted-by":"crossref","first-page":"7294","DOI":"10.1021\/bi982898z","article-title":"Characterization of sphingolipids from mycopathogens: factors correlating with expression of 2-hydroxy fatty acyl (E)-delta 3-unsaturation in cerebrosides of Paracoccidioides brasiliensis and Aspergillus fumigatus","volume":"38","author":"Toledo","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/j.micinf.2004.03.004_BIB23","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/glycob\/11.2.113","article-title":"Characterization of cerebrosides from the thermally dimorphic mycopathogen Histoplasma capsulatum: expression of 2-hydroxy fatty N-acyl (E)-\u03b43-unsaturation correlates with the yeast-mycelium phase transition","volume":"11","author":"Toledo","year":"2001","journal-title":"Glycobiology"},{"key":"10.1016\/j.micinf.2004.03.004_BIB24","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0009-3084(94)90043-4","article-title":"Structural determination of N-2\u2032-hydroxyoctadecenoyl-1-O-beta-d-glucopyranosyl-9-methyl-4, 8-sphingadienine from species of Aspergillus","volume":"70","author":"Villas-Boas","year":"1994","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.micinf.2004.03.004_BIB25","doi-asserted-by":"crossref","first-page":"3900","DOI":"10.1074\/jbc.M311165200","article-title":"Defensins from insects and plants interact with fungal glucosylceramides","volume":"279","author":"Thevissen","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.micinf.2004.03.004_BIB26","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/glycob\/11.2.105","article-title":"Characterization of monoclonal antibody MEST-2 specific to glucosylceramide of fungi and plants","volume":"11","author":"Toledo","year":"2001","journal-title":"Glycobiology"},{"key":"10.1016\/j.micinf.2004.03.004_BIB27","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/BF00492225","article-title":"Effect of environmental factors on Fonsecaea pedrosoi morphogenesis with emphasis on sclerotic cells induced by propranolol","volume":"119","author":"Alviano","year":"1992","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micinf.2004.03.004_BIB28","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/BF00493594","article-title":"Effect of carbon source on conidiogenesis in Fonsecaea dermatitidis, agent of chromomycosis","volume":"58","author":"Butterfield","year":"1976","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micinf.2004.03.004_BIB29","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the isolation and purification of total lipids from animal tissues","volume":"226","author":"Folch","year":"1957","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.micinf.2004.03.004_BIB30","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0076-6879(94)30025-9","article-title":"Thin-layer chromatography of glycosphingolipids","volume":"230","author":"Schnaar","year":"1994","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB31","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1021\/ac60231a048","article-title":"Quantitative determination of monosaccharides as their alditol acetates by gas chromatography","volume":"37","author":"Sawardeker","year":"1965","journal-title":"Anal. Chem."},{"key":"10.1016\/j.micinf.2004.03.004_BIB32","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/0076-6879(90)93448-T","article-title":"Tandem mass spectrometry of glycolipids","volume":"193","author":"Costello","year":"1990","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB33","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/1044-0305(92)87010-V","article-title":"Structure determination of ceramides and neutral glycosphingolipids by collisional activation of [M + Li]+ ions","volume":"3","author":"Ann","year":"1992","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"10.1016\/j.micinf.2004.03.004_BIB34","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0022-2275(20)41224-6","article-title":"Mass spectrometry in lipid research","volume":"1","author":"Ryhager","year":"1960","journal-title":"Lipid Res."},{"key":"10.1016\/j.micinf.2004.03.004_BIB35","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1128\/cdli.4.2.142-146.1997","article-title":"Monoclonal yeast killer toxin-like candidacidal anti-idiotypic antibodies","volume":"4","author":"Polonelli","year":"1997","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB36","doi-asserted-by":"crossref","first-page":"537","DOI":"10.2165\/00128071-200304080-00003","article-title":"Therapeutic approaches to subcutaneous mycoses","volume":"4","author":"Koga","year":"2003","journal-title":"Am. J. Clin. Dermatol."},{"key":"10.1016\/j.micinf.2004.03.004_BIB37","doi-asserted-by":"crossref","first-page":"136","DOI":"10.2741\/A270","article-title":"Mechanism of action of antibody to capsular polysaccharide in Cryptococcus neoformans infection","volume":"3","author":"Feldmesser","year":"1998","journal-title":"Front Biosci."}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457904001017?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457904001017?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:11:43Z","timestamp":1761142303000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457904001017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":37,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["S1286457904001017"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2004.03.004","relation":{},"ISSN":["1286-4579"],"issn-type":[{"value":"1286-4579","type":"print"}],"subject":[],"published":{"date-parts":[[2004,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A monoclonal antibody to glucosylceramide inhibits the growth of Fonsecaea pedrosoi and enhances the antifungal action of mouse macrophages","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2004.03.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 \u00c9ditions scientifiques et m\u00e9dicales Elsevier SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}