{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:53:21Z","timestamp":1764996801155,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","issue":"12-13","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T00:00:00Z","timestamp":1701129600000},"content-version":"vor","delay-in-days":6267,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1016\/j.micinf.2006.08.013","type":"journal-article","created":{"date-parts":[[2006,9,19]],"date-time":"2006-09-19T12:06:39Z","timestamp":1158667599000},"page":"2803-2810","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Differential roles of the co-stimulatory molecules GITR and CTLA-4 in the immune response to Trichinella spiralis"],"prefix":"10.1016","volume":"8","author":[{"given":"Rebecca C.","family":"Furze","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona J.","family":"Culley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murray E.","family":"Selkirk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.micinf.2006.08.013_bib1","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/nri1183","article-title":"Immune regulation by helminth parasites: cellular and molecular mechanisms","volume":"3","author":"Maizels","year":"2003","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib2","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.4049\/jimmunol.173.4.2211","article-title":"Regulatory cells and infectious agents: detentes cordiale and contraire","volume":"173","author":"Rouse","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib3","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/S1286-4579(02)00014-X","article-title":"Antigen-specific T regulatory-1 cells are associated with immunosuppression in a chronic helminth infection (onchocerciasis)","volume":"4","author":"Satoguina","year":"2002","journal-title":"Microbes Infect."},{"key":"10.1016\/j.micinf.2006.08.013_bib4","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.4049\/jimmunol.170.4.1930","article-title":"CTLA-4 in filarial infections: implications for a role in diminished T cell reactivity","volume":"170","author":"Steel","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib5","doi-asserted-by":"crossref","first-page":"4924","DOI":"10.4049\/jimmunol.174.8.4924","article-title":"Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo","volume":"174","author":"Taylor","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1385\/CRIAI:26:1:35","article-title":"Regulation of allergy and autoimmunity in helminth infection","volume":"26","author":"Wilson","year":"2004","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib7","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/ni1180","article-title":"Mechanisms of suppression by suppressor T cells","volume":"6","author":"Von Boehmer","year":"2005","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib8","doi-asserted-by":"crossref","first-page":"3789","DOI":"10.4049\/jimmunol.166.6.3789","article-title":"IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo","volume":"166","author":"Hara","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib9","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1093\/intimm\/5.11.1461","article-title":"Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice","volume":"5","author":"Powrie","year":"1993","journal-title":"Int. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib10","doi-asserted-by":"crossref","first-page":"10398","DOI":"10.1073\/pnas.0403342101","article-title":"Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease","volume":"101","author":"Paust","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.micinf.2006.08.013_bib11","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/eji.200324804","article-title":"GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations","volume":"34","author":"Ronchetti","year":"2004","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib12","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1002\/eji.200425818","article-title":"GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily","volume":"35","author":"Nocentini","year":"2005","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib13","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/ni759","article-title":"Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance","volume":"3","author":"Shimizu","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib14","doi-asserted-by":"crossref","first-page":"708","DOI":"10.4049\/jimmunol.171.2.708","article-title":"Regulation of murine inflammatory bowel disease by CD25+ and CD25-CD4+ glucocorticoid-induced TNF receptor family-related gene+ regulatory T cells","volume":"171","author":"Uraushihara","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib15","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0005-2736(96)00022-3","article-title":"Structural organisation and lipid composition of the epicuticular accessory layer of infective larvae of Trichinella spiralis","volume":"1281","author":"Gounaris","year":"1996","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.micinf.2006.08.013_bib16","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1365-3024.2005.00761.x","article-title":"Comparative dynamics and phenotype of the murine immune response to Trichinella spiralis and Trichinella pseudospiralis","volume":"27","author":"Furze","year":"2005","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib17","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1084\/jem.183.6.2541","article-title":"CTLA-4 ligation blocks CD28-dependent T cell activation","volume":"183","author":"Walunas","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micinf.2006.08.013_bib18","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1002\/(SICI)1521-4141(199811)28:11<3435::AID-IMMU3435>3.0.CO;2-P","article-title":"CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro","volume":"28","author":"Read","year":"1998","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib19","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1084\/jem.186.2.183","article-title":"Protective immunity to nematode infection is induced by CTLA-4 blockade","volume":"186","author":"McCoy","year":"1997","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micinf.2006.08.013_bib20","doi-asserted-by":"crossref","first-page":"5008","DOI":"10.4049\/jimmunol.173.8.5008","article-title":"Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells","volume":"173","author":"Stephens","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib21","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1084\/jem.153.2.423","article-title":"IgE antibody and resistance to infection. Selective suppression of the IgE antibody response in rats diminishes the resistance and the eosinophil response to Trichinella spiralis infection","volume":"153","author":"Dessein","year":"1981","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micinf.2006.08.013_bib22","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.4049\/jimmunol.172.2.1139","article-title":"IgE enhances parasite clearance and regulates mast cell responses in mice infected with Trichinella spiralis","volume":"172","author":"Gurish","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib23","doi-asserted-by":"crossref","first-page":"4034","DOI":"10.1128\/IAI.73.7.4034-4042.2005","article-title":"Regulatory T cells modulate Th2 responses induced by Brugia pahangi third-stage larvae","volume":"73","author":"Gillan","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2006.08.013_bib24","doi-asserted-by":"crossref","first-page":"5530","DOI":"10.4049\/jimmunol.165.10.5530","article-title":"Inhibition of IgG1 and IgE production by stimulation of the B cell CTLA-4 receptor","volume":"165","author":"Pioli","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib25","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/1521-4141(200202)32:2<585::AID-IMMU585>3.0.CO;2-U","article-title":"Blockade of CTLA-4 enhances allergic sensitization and eosinophilic airway inflammation in genetically predisposed mice","volume":"32","author":"Hellings","year":"2002","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib26","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1378\/chest.122.1.171","article-title":"Association of asthma severity and bronchial hyperresponsiveness with a polymorphism in the cytotoxic T-lymphocyte antigen-4 gene","volume":"122","author":"Lee","year":"2002","journal-title":"Chest"},{"key":"10.1016\/j.micinf.2006.08.013_bib27","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.4049\/jimmunol.171.6.3142","article-title":"IL-10 prevents liver necrosis during murine infection with Trichinella spiralis","volume":"171","author":"Bliss","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2006.08.013_bib28","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1645\/0022-3395(2000)086[0841:SOMSIT]2.0.CO;2","article-title":"Suppression of multiple sclerosis in the rat during infection with Trichinella pseudospiralis","volume":"86","author":"Boles","year":"2000","journal-title":"J. Parasitol."},{"key":"10.1016\/j.micinf.2006.08.013_bib29","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1128\/IAI.74.3.1924-1932.2006","article-title":"Amelioration of influenza-induced pathology in mice by coinfection with Trichinella spiralis","volume":"74","author":"Furze","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2006.08.013_bib30","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/0020-7519(91)90169-8","article-title":"Effect of acute versus chronic Trichinella pseudospiralis infections on systemic cell-mediated\u00a0immunity","volume":"21","author":"Stewart","year":"1991","journal-title":"Int. J. Parasitol."}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457906003108?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457906003108?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:17:37Z","timestamp":1761142657000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457906003108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":30,"journal-issue":{"issue":"12-13","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["S1286457906003108"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2006.08.013","relation":{},"ISSN":["1286-4579"],"issn-type":[{"type":"print","value":"1286-4579"}],"subject":[],"published":{"date-parts":[[2006,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential roles of the co-stimulatory molecules GITR and CTLA-4 in the immune response to Trichinella spiralis","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2006.08.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}