{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:04:17Z","timestamp":1790316257140,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":6058,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1016\/j.micinf.2007.03.008","type":"journal-article","created":{"date-parts":[[2007,3,22]],"date-time":"2007-03-22T07:00:49Z","timestamp":1174546849000},"page":"898-906","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus"],"prefix":"10.1016","volume":"9","author":[{"given":"Yassina","family":"Bechah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Capo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges E.","family":"Grau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Raoult","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Mege","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micinf.2007.03.008_bib1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0923-2508(00)00116-9","article-title":"A century of typhus, lice and Rickettsia","volume":"151","author":"Andersson","year":"2000","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.micinf.2007.03.008_bib2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0140-6736(97)12433-3","article-title":"Outbreak of epidemic typhus associated with trench fever in Burundi","volume":"352","author":"Raoult","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.micinf.2007.03.008_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3201\/eid0701.010101","article-title":"Emerging infectious diseases in Russia, 1990\u20131999","volume":"7","author":"Netesov","year":"2001","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.micinf.2007.03.008_bib4","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1001\/jama.1981.03310470032022","article-title":"Epidemic typhus in the United States associated with flying squirrels","volume":"245","author":"Duma","year":"1981","journal-title":"JAMA"},{"key":"10.1016\/j.micinf.2007.03.008_bib5","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/S0140-6736(00)04339-7","article-title":"Brill-Zinsser disease","volume":"357","author":"Lutwick","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.micinf.2007.03.008_bib6","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/24094","article-title":"The genome sequence of Rickettsia prowazekii and the origin of mitochondria","volume":"396","author":"Andersson","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.micinf.2007.03.008_bib7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1093\/infdis\/91.1.72","article-title":"Studies on the toxicity of typhus rickettsiae. I. Susceptibility of the white rat, with a note on pathologic changes","volume":"91","author":"Neva","year":"1952","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micinf.2007.03.008_bib8","doi-asserted-by":"crossref","first-page":"455","DOI":"10.4049\/jimmunol.60.4.455","article-title":"Infection of guinea pigs with massive doses of rickettsiae of epidemic and murine typhus","volume":"60","author":"Perez Gallardo","year":"1948","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2007.03.008_bib9","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1093\/infdis\/97.1.73","article-title":"Studies on the toxicity of typhus rickettsiae. III. Observations on the mechanism of toxic death in white mice and white rats","volume":"97","author":"Neva","year":"1955","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micinf.2007.03.008_bib10","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1093\/infdis\/117.4.285","article-title":"Experimental infection with Rickettsia prowazekii in rhesus and vervet monkeys","volume":"117","author":"Barker","year":"1967","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micinf.2007.03.008_bib11","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1128\/iai.30.1.219-223.1980","article-title":"Epidemic typhus infection in cynomolgus monkeys (Macaca fascicularis)","volume":"30","author":"Gonder","year":"1980","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2007.03.008_bib12","doi-asserted-by":"crossref","first-page":"58","DOI":"10.2460\/javma.1995.207.01.58","article-title":"Evaluation of the pathogenic potential of Rickettsia canada and Rickettsia prowazekii organisms in dogs","volume":"207","author":"Breitschwerdt","year":"1995","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.micinf.2007.03.008_bib13","doi-asserted-by":"crossref","first-page":"950","DOI":"10.4269\/ajtmh.1971.20.950","article-title":"Experimental infections of lambs with Rickettsia prowazekii","volume":"20","author":"Ormsbee","year":"1971","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.micinf.2007.03.008_bib14","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1093\/infdis\/155.5.1059","article-title":"In vitro antibiotic susceptibility of Rickettsia rickettsii and Rickettsia conorii: plaque assay and microplaque colorimetric assay","volume":"155","author":"Raoult","year":"1987","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micinf.2007.03.008_bib15","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1099\/00207713-47-2-252","article-title":"Citrate synthase gene comparison, a new tool for phylogenetic analysis, and its application for the rickettsiae","volume":"47","author":"Roux","year":"1997","journal-title":"Int. J. Syst. Bact."},{"key":"10.1016\/j.micinf.2007.03.008_bib16","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1128\/JCM.36.8.2380-2382.1998","article-title":"Purification of Encephalitozoon cultures contaminated by mycoplasmas by murine intraperitoneal inoculation","volume":"36","author":"Ridoux","year":"1998","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micinf.2007.03.008_bib17","doi-asserted-by":"crossref","first-page":"428","DOI":"10.3201\/eid1203.050888","article-title":"Rickettsia prowazekii and real-time polymerase chain reaction","volume":"12","author":"Svraka","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.micinf.2007.03.008_bib18","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1471-2180-4-21","article-title":"Multi-pathogens sequence containing plasmids as positive controls for universal detection of potential agents of bioterrorism","volume":"4","author":"Charrel","year":"2004","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micinf.2007.03.008_bib19","doi-asserted-by":"crossref","first-page":"4575","DOI":"10.4049\/jimmunol.175.7.4575","article-title":"IL-16 is critical for Tropheryma whipplei replication in Whipple's disease","volume":"175","author":"Desnues","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2007.03.008_bib20","series-title":"Rickettsia and rickettsial diseases. Veda","first-page":"43","article-title":"Genetic, biological and serological differentiation of Rickettsia prowazekii and Rickettsia typhi","author":"Eremeeva","year":"1996"},{"key":"10.1016\/j.micinf.2007.03.008_bib21","series-title":"Biology of Rickettsial Disease","first-page":"115","article-title":"Pathology and pathogenesis of the vasculotropic rickettsioses","author":"Walker","year":"1988"},{"key":"10.1016\/j.micinf.2007.03.008_bib22","series-title":"The Etiology and Pathology of Typhus","first-page":"162","article-title":"Pathology of typhus in man","author":"Wolbach","year":"1922"},{"key":"10.1016\/j.micinf.2007.03.008_bib23","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1093\/ajcp\/87.5.669","article-title":"The pathology of fatal Mediterranean spotted fever","volume":"87","author":"Walker","year":"1987","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.micinf.2007.03.008_bib24","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/0002-8703(80)90072-1","article-title":"Rickettsial vasculitis","volume":"100","author":"Walker","year":"1980","journal-title":"Am. Heart J."},{"key":"10.1016\/j.micinf.2007.03.008_bib25","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/334255a0","article-title":"Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells","volume":"334","author":"Stevens","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.micinf.2007.03.008_bib26","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1084\/jem.157.6.1780","article-title":"Interferon like factors from antigen- and mitogen-stimulated leukocytes with antirickettsial and cytolytic actions on Rickettsia prowazekii. Infected human endothelial cells, fibroblasts, and macrophages","volume":"157","author":"Wisseman","year":"1983","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micinf.2007.03.008_bib27","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S1286-4579(02)01581-2","article-title":"Mechanisms of immunity against rickettsiae. New perspectives and opportunities offered by unusual intracellular parasites","volume":"4","author":"Valbuena","year":"2002","journal-title":"Microbes Infect"},{"key":"10.1016\/j.micinf.2007.03.008_bib28","first-page":"1016","article-title":"Interferon-gamma and tumor necrosis factor-alpha exert their antirickettsial effect via induction of synthesis of nitric oxide","volume":"143","author":"Feng","year":"1993","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.micinf.2007.03.008_bib29","doi-asserted-by":"crossref","first-page":"165","DOI":"10.4049\/jimmunol.163.1.165","article-title":"Differential expression and cross-regulatory function of RANTES during mycobacterial (type 1) and schistosomal (type 2) antigen-elicited granulomatous inflammation","volume":"163","author":"Chensue","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2007.03.008_bib30","first-page":"1471","article-title":"Rickettsia australis infection: a murine model of a highly invasive vasculopathic rickettsiosis","volume":"142","author":"Feng","year":"1993","journal-title":"Am. J. Pathol."}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457907001232?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457907001232?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:20:04Z","timestamp":1761142804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457907001232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["S1286457907001232"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2007.03.008","relation":{},"ISSN":["1286-4579"],"issn-type":[{"value":"1286-4579","type":"print"}],"subject":[],"published":{"date-parts":[[2007,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2007.03.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}