{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T18:11:20Z","timestamp":1783707080692,"version":"3.55.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"10-11","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T00:00:00Z","timestamp":1701129600000},"content-version":"vor","delay-in-days":5597,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.micinf.2008.06.015","type":"journal-article","created":{"date-parts":[[2008,7,20]],"date-time":"2008-07-20T04:06:05Z","timestamp":1216526765000},"page":"1210-1217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Kinetics of cytokine profile during intraperitoneal inoculation of Japanese encephalitis virus in BALB\/c mice model"],"prefix":"10.1016","volume":"10","author":[{"given":"Vandana","family":"Saxena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asha","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narendra","family":"Krishnani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tapan N.","family":"Dhole","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micinf.2008.06.015_bib1","series-title":"Vaccines","first-page":"672","article-title":"Japanese encephalitis vaccine","author":"Tsai","year":"1999"},{"key":"10.1016\/j.micinf.2008.06.015_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/sj.icb.7100012","article-title":"Immunopathology of flavivirus infections","volume":"85","author":"King","year":"2007","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.micinf.2008.06.015_bib3","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1093\/infdis\/155.4.797","article-title":"Levels of interferon in the plasma and cerebrospinal fluid of patients with acute Japanese encephalitis","volume":"155","author":"Burke","year":"1987","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micinf.2008.06.015_bib4","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/(SICI)1096-9071(199702)51:2<132::AID-JMV8>3.0.CO;2-8","article-title":"Correlation of tumor necrosis factor levels in the serum and cerebrospinal fluid with clinical outcome in Japanese encephalitis patients","volume":"51","author":"Ravi","year":"1997","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.micinf.2008.06.015_bib5","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0167-4781(00)00262-1","article-title":"Japanese encephalitis virus up-regulates expression of macrophage migration inhibitory factor (MIF) mRNA in the mouse brain","volume":"1517","author":"Suzuki","year":"2000","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1016\/j.micinf.2008.06.015_bib6","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1099\/0022-1317-49-7-607","article-title":"Secretion of the chemokine IL-8 during Japanese encephalitis virus infection","volume":"49","author":"Singh","year":"2000","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.micinf.2008.06.015_bib7","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1086\/423328","article-title":"Proinflammatory cytokines and chemokines in humans with Japanese encephalitis","volume":"190","author":"Winter","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micinf.2008.06.015_bib8","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/glia.20474","article-title":"Proinflammatory mediators released by activated microglia induces neuronal death in Japanese encephalitis","volume":"55","author":"Ghoshal","year":"2007","journal-title":"Glia"},{"key":"10.1016\/j.micinf.2008.06.015_bib9","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.neulet.2007.04.071","article-title":"Japanese encephalitis virus infection decrease endogenous IL-10 production: correlation with microglial activation and neuronal death","volume":"420","author":"Swarup","year":"2007","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.micinf.2008.06.015_bib10","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s00705-007-1098-7","article-title":"An insufficient anti-inflammatory cytokine response in mice brain is associated with increased tissue pathology and viral load during Japanese encephalitis virus infection","volume":"153","author":"Saxena","year":"2008","journal-title":"Arch. Virol."},{"key":"10.1016\/j.micinf.2008.06.015_bib11","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3181\/00379727-123-31418","article-title":"The effect of host age, viral dose and route of inoculation on inapparent infection in mice with Japanese encephalitis virus","volume":"123","author":"Grossberg","year":"1966","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.micinf.2008.06.015_bib12","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1128\/iai.34.1.26-29.1981","article-title":"Congenital infection of mice with Japanese encephalitis virus","volume":"34","author":"Mathur","year":"1981","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2008.06.015_bib13","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1099\/0022-1317-67-2-381","article-title":"Persistence, latency and reactivation of Japanese encephalitis virus infection in mice","volume":"67","author":"Mathur","year":"1986","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micinf.2008.06.015_bib14","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1099\/vir.0.18676-0","article-title":"T helper responses to Japanese encephalitis virus infection are dependent on the route of inoculation and the strain of mouse used","volume":"84","author":"Ramakrishna","year":"2003","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micinf.2008.06.015_bib15","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1161\/01.ATV.15.2.258","article-title":"Venous thrombosis-associated inflammation and attenuation with neutralizing antibodies to cytokines and adhesion molecules","volume":"15","author":"Wakefield","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.micinf.2008.06.015_bib16","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"Biol. Chem."},{"key":"10.1016\/j.micinf.2008.06.015_bib17","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1365-2249.1991.tb05813.x","article-title":"Neutrophil chemotactic factor produced by Japanese encephalitis virus stimulated macrophages","volume":"86","author":"Khanna","year":"1991","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.micinf.2008.06.015_bib18","first-page":"603","article-title":"Breakdown of blood\u2013brain barrier by virus induced cytokine during Japanese encephalitis virus infection","volume":"73","author":"Mathur","year":"1992","journal-title":"Int. J. Exp. Pathol."},{"key":"10.1016\/j.micinf.2008.06.015_bib19","doi-asserted-by":"crossref","first-page":"5338","DOI":"10.1128\/JVI.00274-06","article-title":"Gamma interferon plays a crucial early antiviral role in protection against West Nile Virus infection","volume":"80","author":"Shrestha","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.micinf.2008.06.015_bib20","first-page":"423","article-title":"Immunopathological study of spleen during Japanese encephalitis virus infection in mice","volume":"69","author":"Mathur","year":"1988","journal-title":"Br. J. Exp. Pathol."},{"key":"10.1016\/j.micinf.2008.06.015_bib21","doi-asserted-by":"crossref","first-page":"926","DOI":"10.4049\/jimmunol.164.2.926","article-title":"Decreased cytomegalovirus expression following proinflammatory cytokine treatment of primary human astrocytes","volume":"164","author":"Cheeran","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2008.06.015_bib22","doi-asserted-by":"crossref","first-page":"5497","DOI":"10.4049\/jimmunol.163.10.5497","article-title":"Inducible nitric oxide synthase mediated protection against Coxsackievirus pancreatitis","volume":"163","author":"Zaragoza","year":"1999","journal-title":"J. Immunol"},{"key":"10.1016\/j.micinf.2008.06.015_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/abbi.2001.2360","article-title":"Induction of nitric oxide synthase during Japanese encephalitis virus infection: evidence of protective role","volume":"391","author":"Saxena","year":"2001","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.micinf.2008.06.015_bib24","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1086\/381768","article-title":"Impaired T helper 1 function of non-structural protein 3-specific T cells in Japanese patients with encephalitis with neurological sequelae","volume":"189","author":"Kumar","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micinf.2008.06.015_bib25","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.neulet.2006.11.070","article-title":"Induction of IP-10 (CXCL10) in astrocytes following Japanese encephalitis","volume":"414","author":"Bhowmick","year":"2007","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.micinf.2008.06.015_bib26","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1099\/0022-1317-64-4-805","article-title":"Host defense mechanisms against Japanese encephalitis virus infection in mice","volume":"64","author":"Mathur","year":"1983","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micinf.2008.06.015_bib27","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1099\/0022-1317-70-2-461","article-title":"Evidence for latency of Japanese encephalitis virus in T lymphocytes","volume":"70","author":"Mathur","year":"1989","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micinf.2008.06.015_bib28","doi-asserted-by":"crossref","first-page":"7363","DOI":"10.1128\/JVI.79.12.7363-7370.2005","article-title":"Vaccinia virus induces strong immunoregulatory cytokine production in healthy human epidermal keratinocytes: a novel strategy for immune evasion","volume":"79","author":"Liu","year":"2005","journal-title":"J. Virol."}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457908002001?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457908002001?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:23:16Z","timestamp":1761142996000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457908002001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":28,"journal-issue":{"issue":"10-11","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S1286457908002001"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2008.06.015","relation":{},"ISSN":["1286-4579"],"issn-type":[{"value":"1286-4579","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Kinetics of cytokine profile during intraperitoneal inoculation of Japanese encephalitis virus in BALB\/c mice model","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2008.06.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}