{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:27:28Z","timestamp":1791070048391,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"14-15","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":5539,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.micinf.2008.09.011","type":"journal-article","created":{"date-parts":[[2008,10,15]],"date-time":"2008-10-15T04:23:05Z","timestamp":1224044585000},"page":"1567-1576","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Complement induction and complement evasion in patients with cerebral aspergillosis"],"prefix":"10.1016","volume":"10","author":[{"given":"G\u00fcnter","family":"Rambach","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Vago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iradj","family":"Mohsenipour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"Lass-Fl\u00f6rl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Defant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhard","family":"W\u00fcrzner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred P.","family":"Dierich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"Speth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micinf.2008.09.011_bib1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/13693780701200372","article-title":"Fungal infections in solid organ transplantation","volume":"45","author":"Silveira","year":"2007","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micinf.2008.09.011_bib2","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2165\/00023210-200721080-00004","article-title":"CNS aspergillosis: recognition, diagnosis and management","volume":"21","author":"Ruhnke","year":"2007","journal-title":"CNS Drugs"},{"key":"10.1016\/j.micinf.2008.09.011_bib3","doi-asserted-by":"crossref","first-page":"4358","DOI":"10.1182\/blood-2002-05-1496","article-title":"Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors","volume":"100","author":"Marr","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.micinf.2008.09.011_bib4","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/sj.bmt.1703812","article-title":"Central nervous system aspergillosis in allogeneic stem cell transplant recipients","volume":"31","author":"Jantunen","year":"2003","journal-title":"Bone Marrow Transplant."},{"issue":"Suppl. 1","key":"10.1016\/j.micinf.2008.09.011_bib5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/13693780400025179","article-title":"The invasive and saprophytic syndromes due to Aspergillus spp.","volume":"43","author":"Hope","year":"2005","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micinf.2008.09.011_bib6","first-page":"37","article-title":"Aspergilloma of the brain: an overview","volume":"51","author":"Nadkarni","year":"2005","journal-title":"J. Postgrad. Med."},{"key":"10.1016\/j.micinf.2008.09.011_bib7","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1439-0507.2007.01345.x","article-title":"Poor efficacy of amphotericin B-based therapy in CNS aspergillosis","volume":"50","author":"Schwartz","year":"2007","journal-title":"Mycoses"},{"key":"10.1016\/j.micinf.2008.09.011_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1462399403006252","article-title":"Innate immunity and brain inflammation: the key role of complement","volume":"5","author":"Francis","year":"2003","journal-title":"Expert Rev. Mol. Med."},{"key":"10.1016\/j.micinf.2008.09.011_bib9","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0161-5890(01)00104-3","article-title":"Neuroinvasion by pathogens: a key role of the complement system","volume":"38","author":"Speth","year":"2002","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.micinf.2008.09.011_bib10","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/j.micinf.2005.04.014","article-title":"Antifungal activity of the local complement system in cerebral aspergillosis","volume":"7","author":"Rambach","year":"2005","journal-title":"Microbes Infect."},{"key":"10.1016\/j.micinf.2008.09.011_bib11","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1128\/iai.58.5.1476-1478.1990","article-title":"Use of DBA\/2 N mice in models of systemic candidiasis and pulmonary and systemic aspergillosis","volume":"58","author":"Hector","year":"1990","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2008.09.011_bib12","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1128\/IAI.01037-07","article-title":"The opportunistic human pathogenic fungus Aspergillus fumigatus evades the host complement system","volume":"76","author":"Behnsen","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2008.09.011_bib13","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.molimm.2007.08.011","article-title":"Immune evasion by acquisition of complement inhibitors: the mould Aspergillus binds both factor H and C4b binding protein","volume":"45","author":"Vogl","year":"2008","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.micinf.2008.09.011_bib14","doi-asserted-by":"crossref","first-page":"3850","DOI":"10.1016\/j.molimm.2007.06.149","article-title":"Complement evasion of pathogens: common strategies are shared by diverse organisms","volume":"44","author":"Zipfel","year":"2007","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.micinf.2008.09.011_bib15","first-page":"27","article-title":"Complement binding to Aspergillus conidia correlates with pathogenicity","volume":"122","author":"Henwick","year":"1993","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.micinf.2008.09.011_bib16","doi-asserted-by":"crossref","first-page":"3031","DOI":"10.1128\/JB.180.12.3031-3038.1998","article-title":"The developmentally regulated alb1 gene of Aspergillus fumigatus: its role in modulation of conidial morphology and virulence","volume":"180","author":"Tsai","year":"1998","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micinf.2008.09.011_bib17","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1046\/j.1365-2958.1997.5681921.x","article-title":"Aspergillus fumigatus arp1 modulates conidial pigmentation and complement deposition","volume":"26","author":"Tsai","year":"1997","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micinf.2008.09.011_bib18","doi-asserted-by":"crossref","first-page":"3508","DOI":"10.1128\/iai.58.11.3508-3515.1990","article-title":"Aspergillus fumigatus complement inhibitor: production, characterization and purification by hydrophobic interaction and thin-layer chromatography","volume":"58","author":"Washburn","year":"1990","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2008.09.011_bib19","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1093\/infdis\/154.6.944","article-title":"Inhibition of complement by culture supernatants of Aspergillus fumigates","volume":"154","author":"Washburn","year":"1986","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micinf.2008.09.011_bib20","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1128\/iai.60.5.1913-1918.1992","article-title":"Interactions between conidia of Aspergillus fumigatus and human complement component C3","volume":"60","author":"Sturtevant","year":"1992","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2008.09.011_bib21","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1046\/j.1365-2222.2000.00796.x","article-title":"Putative virulence factors of Aspergillus fumigatus","volume":"30","author":"Tomee","year":"2000","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.micinf.2008.09.011_bib22","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1177\/29.11.6172466","article-title":"Protein A, avidin, and biotin in immunohistochemistry","volume":"29","author":"Hsu","year":"1981","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.micinf.2008.09.011_bib23","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1038\/nn1997","article-title":"Microglia: active sensor and versatile effector cells in the normal and pathologic brain","volume":"10","author":"Hanisch","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.micinf.2008.09.011_bib24","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1093\/intimm\/12.7.1015","article-title":"Expression of a complete and functional complement system by human neuronal cells in vitro","volume":"12","author":"Thomas","year":"2000","journal-title":"Int. Immunol."},{"key":"10.1016\/j.micinf.2008.09.011_bib25","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0304-3940(95)11923-K","article-title":"Differential regulation of C3 gene expression in human astroglioma cells by interferon-gamma and interleukin-1 beta","volume":"197","author":"Barnum","year":"1995","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.micinf.2008.09.011_bib26","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/(SICI)1098-1136(20000101)29:1<91::AID-GLIA9>3.0.CO;2-I","article-title":"Pro-inflammatory cytokines induce the transcription factors C\/EBPbeta and C\/EBPdelta in astrocytes","volume":"29","author":"Cardinaux","year":"2000","journal-title":"Glia"},{"key":"10.1016\/j.micinf.2008.09.011_bib27","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1146\/annurev.iy.13.040195.001425","article-title":"Transcriptional regulation of complement genes","volume":"13","author":"Volanakis","year":"1995","journal-title":"Annu Rev. Immunol."},{"key":"10.1016\/j.micinf.2008.09.011_bib28","first-page":"99","article-title":"Development of a murine model of cerebral aspergillosis","volume":"79","author":"Chiller","year":"2007","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.micinf.2008.09.011_bib29","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s00401-007-0255-0","article-title":"A model of cerebral aspergillosis in non-immunosuppressed nursing rats","volume":"114","author":"Zimmerli","year":"2007","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.micinf.2008.09.011_bib30","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1196\/annals.1403.002","article-title":"The brain as a target for inflammatory processes and neuroprotective strategies","volume":"1122","author":"Skaper","year":"2007","journal-title":"Ann. N Y Acad. Sci."}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457908002682?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457908002682?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:24:22Z","timestamp":1761143062000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457908002682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":30,"journal-issue":{"issue":"14-15","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S1286457908002682"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2008.09.011","relation":{},"ISSN":["1286-4579"],"issn-type":[{"value":"1286-4579","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Complement induction and complement evasion in patients with cerebral aspergillosis","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2008.09.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}