{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:53:13Z","timestamp":1791060793588,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"6-7","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":5358,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.micinf.2009.04.010","type":"journal-article","created":{"date-parts":[[2009,4,18]],"date-time":"2009-04-18T05:05:01Z","timestamp":1240031101000},"page":"689-697","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Brucella abortus activates human neutrophils"],"prefix":"10.1016","volume":"11","author":[{"given":"Astrid","family":"Zwerdling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Victoria","family":"Delpino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina A.","family":"Pasquevich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Barrionuevo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Cassataro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Garc\u00eda Samartino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo H.","family":"Giambartolomei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.micinf.2009.04.010_bib1","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1093\/clinids\/5.5.821","article-title":"Human brucellosis","volume":"5","author":"Young","year":"1983","journal-title":"Rev. Infect. Dis."},{"issue":"4","key":"10.1016\/j.micinf.2009.04.010_bib2","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00005792-199607000-00003","article-title":"Complications associated with brucella melitensis infection: a study of 530 cases","volume":"75","author":"Colmenero","year":"1996","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"10.1016\/j.micinf.2009.04.010_bib3","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1136\/ard.50.1.23","article-title":"Osteoarticular complications of brucellosis","volume":"50","author":"Colmenero","year":"1991","journal-title":"Ann. Rheum. Dis."},{"issue":"3","key":"10.1016\/j.micinf.2009.04.010_bib4","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/rheumatology\/36.3.377","article-title":"Arthritis of shoulder and spinal cord compression due to brucella disc infection","volume":"36","author":"Ibero","year":"1997","journal-title":"Br. J. Rheumatol."},{"issue":"3","key":"10.1016\/j.micinf.2009.04.010_bib5","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s10067-002-8283-6","article-title":"Leukocyte count in the synovial fluid of children with culture-proven brucellar arthritis","volume":"21","author":"Press","year":"2002","journal-title":"Clin. Rheumatol."},{"issue":"12","key":"10.1016\/j.micinf.2009.04.010_bib6","first-page":"478","article-title":"[Neutrophilic pleocytosis in brucella meningitis]","volume":"99","author":"Alba","year":"1992","journal-title":"Med. Clin. (Barc.)"},{"issue":"4","key":"10.1016\/j.micinf.2009.04.010_bib7","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1258\/004947506778604841","article-title":"Exudative pleural effusion due to brucellosis in a patient with chronic obstructive pulmonary disease","volume":"36","author":"Zengi","year":"2006","journal-title":"Trop. Doct."},{"issue":"7","key":"10.1016\/j.micinf.2009.04.010_bib8","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0167-5699(97)01087-6","article-title":"Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis","volume":"18","author":"Edwards","year":"1997","journal-title":"Immunol. Today"},{"issue":"7","key":"10.1016\/j.micinf.2009.04.010_bib9","doi-asserted-by":"crossref","first-page":"4635","DOI":"10.4049\/jimmunol.173.7.4635","article-title":"Lipoproteins, not lipopolysaccharide, are the key mediators of the proinflammatory response elicited by heat-killed brucella abortus","volume":"173","author":"Giambartolomei","year":"2004","journal-title":"J. Immunol."},{"issue":"12\u201313","key":"10.1016\/j.micinf.2009.04.010_bib10","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.micinf.2008.07.035","article-title":"Brucella lipoproteins mimic dendritic cell maturation induced by brucella abortus","volume":"10","author":"Zwerdling","year":"2008","journal-title":"Microbes Infect."},{"issue":"3","key":"10.1016\/j.micinf.2009.04.010_bib11","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1128\/iai.23.3.737-742.1979","article-title":"Interaction of polymorphonuclear leukocytes with smooth and rough strains of brucella abortus","volume":"23","author":"Kreutzer","year":"1979","journal-title":"Infect. Immun."},{"issue":"1","key":"10.1016\/j.micinf.2009.04.010_bib12","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1128\/iai.46.1.224-230.1984","article-title":"Ingestion and intracellular survival of brucella abortus in human and bovine polymorphonuclear leukocytes","volume":"46","author":"Riley","year":"1984","journal-title":"Infect. Immun."},{"issue":"1\u20132","key":"10.1016\/j.micinf.2009.04.010_bib13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0022-1759(98)00136-7","article-title":"A simple flow cytometry assay using dihydrorhodamine for the measurement of the neutrophil respiratory burst in whole blood: comparison with the quantitative nitrobluetetrazolium test","volume":"219","author":"Richardson","year":"1998","journal-title":"J. Immunol. Methods"},{"issue":"Suppl. 7","key":"10.1016\/j.micinf.2009.04.010_bib14","doi-asserted-by":"crossref","first-page":"S421","DOI":"10.1086\/431992","article-title":"The role of toll-like receptors in the regulation of neutrophil migration, activation, and apoptosis","volume":"41","author":"Sabroe","year":"2005","journal-title":"Clin. Infect. Dis."},{"issue":"1","key":"10.1016\/j.micinf.2009.04.010_bib15","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1172\/JCI113887","article-title":"Lipopolysaccharide priming of human neutrophils for an enhanced respiratory burst. Role of intracellular free calcium","volume":"83","author":"Forehand","year":"1989","journal-title":"J. Clin. Invest."},{"issue":"8","key":"10.1016\/j.micinf.2009.04.010_bib16","doi-asserted-by":"crossref","first-page":"5229","DOI":"10.4049\/jimmunol.173.8.5229","article-title":"Bacterial lipoprotein delays apoptosis in human neutrophils through inhibition of caspase-3 activity: regulatory roles for cd14 and tlr-2","volume":"173","author":"Power","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2009.04.010_bib17","series-title":"Brucellosis","article-title":"Histopathological features","author":"Madkour","year":"2001"},{"issue":"1","key":"10.1016\/j.micinf.2009.04.010_bib18","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1128\/IAI.01039-07","article-title":"Phagocytosis of Borrelia burgdorferi, the lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytes","volume":"76","author":"Cruz","year":"2008","journal-title":"Infect. Immun."},{"issue":"5","key":"10.1016\/j.micinf.2009.04.010_bib19","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1006\/mpat.2002.0531","article-title":"Membrane sorting during swimming internalization of brucella is required for phagosome trafficking decisions","volume":"33","author":"Kim","year":"2002","journal-title":"Microb. Pathog."},{"issue":"3","key":"10.1016\/j.micinf.2009.04.010_bib20","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1128\/IAI.70.3.1640-1644.2002","article-title":"Role of cholesterol and the ganglioside gm(1) in entry and short-term survival of brucella suis in murine macrophages","volume":"70","author":"Naroeni","year":"2002","journal-title":"Infect. Immun."},{"issue":"Pt\u00a017","key":"10.1016\/j.micinf.2009.04.010_bib21","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1242\/jcs.01270","article-title":"Lateral diffusion of toll-like receptors reveals that they are transiently confined within lipid rafts on the plasma membrane","volume":"117","author":"Triantafilou","year":"2004","journal-title":"J. Cell Sci."},{"issue":"5","key":"10.1016\/j.micinf.2009.04.010_bib22","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1462-5822.2004.00372.x","article-title":"Adherence of brucella to human epithelial cells and macrophages is mediated by sialic acid residues","volume":"6","author":"Castaneda-Roldan","year":"2004","journal-title":"Cell Microbiol."},{"issue":"9","key":"10.1016\/j.micinf.2009.04.010_bib23","doi-asserted-by":"crossref","first-page":"4960","DOI":"10.1128\/IAI.67.9.4960-4962.1999","article-title":"Outer membrane proteins Omp1 0, Omp1 6, and Omp19 of Brucella spp. are lipoproteins","volume":"67","author":"Tibor","year":"1999","journal-title":"Infect. Immun."},{"issue":"12","key":"10.1016\/j.micinf.2009.04.010_bib24","doi-asserted-by":"crossref","first-page":"8353","DOI":"10.1128\/IAI.73.12.8353-8361.2005","article-title":"Whole-genome analyses of speciation events in pathogenic brucellae","volume":"73","author":"Chain","year":"2005","journal-title":"Infect. Immun."},{"issue":"3","key":"10.1016\/j.micinf.2009.04.010_bib25","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.4049\/jimmunol.167.3.1542","article-title":"Mycobacterium tuberculosis 19-kda lipoprotein promotes neutrophil activation","volume":"167","author":"Neufert","year":"2001","journal-title":"J. Immunol."},{"issue":"10","key":"10.1016\/j.micinf.2009.04.010_bib26","doi-asserted-by":"crossref","first-page":"4838","DOI":"10.4049\/jimmunol.158.10.4838","article-title":"Borrelia burgdorferi outer surface protein a (ospa) activates and primes human neutrophils","volume":"158","author":"Morrison","year":"1997","journal-title":"J Immunol."},{"issue":"3","key":"10.1016\/j.micinf.2009.04.010_bib27","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.rdc.2004.04.010","article-title":"Apoptosis in rheumatoid arthritis: friend or foe","volume":"30","author":"Liu","year":"2004","journal-title":"Rheum. Dis. Clin. North Am."},{"issue":"6917","key":"10.1016\/j.micinf.2009.04.010_bib28","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/nature01320","article-title":"Points of control in inflammation","volume":"420","author":"Nathan","year":"2002","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.micinf.2009.04.010_bib29","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0889-857X(03)00107-8","article-title":"Phagocytes: mechanisms of inflammation and tissue destruction","volume":"30","author":"Liu","year":"2004","journal-title":"Rheum. Dis. Clin. North Am."},{"issue":"3","key":"10.1016\/j.micinf.2009.04.010_bib30","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1128\/iai.62.3.910-914.1994","article-title":"Phagocytic cell function in active brucellosis","volume":"62","author":"Ocon","year":"1994","journal-title":"Infect. Immun."}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457909000781?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457909000781?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:24:31Z","timestamp":1761143071000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457909000781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":30,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S1286457909000781"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2009.04.010","relation":{},"ISSN":["1286-4579"],"issn-type":[{"value":"1286-4579","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Brucella abortus activates human neutrophils","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2009.04.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}