{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:01:25Z","timestamp":1790755285328,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":3713,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Disease","doi-asserted-by":"crossref","award":["#Y1-AI-6153-01\/#224-06-1322"],"award-info":[{"award-number":["#Y1-AI-6153-01\/#224-06-1322"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]},{"name":"NIH, Bethesda, MD"},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","award":["MOP 89812"],"award-info":[{"award-number":["MOP 89812"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.micinf.2013.07.005","type":"journal-article","created":{"date-parts":[[2013,7,20]],"date-time":"2013-07-20T12:32:19Z","timestamp":1374323539000},"page":"816-827","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Generation of protection against Francisella novicida in mice depends on the pathogenicity protein PdpA, but not PdpC or PdpD"],"prefix":"10.1016","volume":"15","author":[{"given":"Alicia Y.","family":"Chou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikki J.","family":"Kennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli B.","family":"Nix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal L.","family":"Schmerk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis E.","family":"Nano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen L.","family":"Elkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micinf.2013.07.005_bib1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1128\/CMR.15.4.631-646.2002","article-title":"Tularemia","volume":"15","author":"Ellis","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.micinf.2013.07.005_bib2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fmicb.2011.00026","article-title":"Immunity to Francisella","volume":"2","author":"Cowley","year":"2011","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib3","series-title":"Bergey's Manual of Systematic Bacteriology","first-page":"200","article-title":"Francisellaceae","author":"Sj\u00f6stedt","year":"2004"},{"key":"10.1016\/j.micinf.2013.07.005_bib4","doi-asserted-by":"crossref","first-page":"415","DOI":"10.4049\/jimmunol.87.4.415","article-title":"Prophylactic effectiveness of live and killed tularemia vaccines","volume":"87","author":"Eigelsbach","year":"1961","journal-title":"J. Immunol."},{"key":"10.1016\/j.micinf.2013.07.005_bib5","doi-asserted-by":"crossref","first-page":"391","DOI":"10.2217\/fmb.11.22","article-title":"Tularemia vaccines: recent developments and remaining hurdles","volume":"6","author":"Conlan","year":"2011","journal-title":"Future Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib6","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1128\/JCM.00995-12","article-title":"Francisella novicida bacteremia after a near-drowning accident","volume":"50","author":"Brett","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib7","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1128\/jcm.34.8.1995-2000.1996","article-title":"Characterization of two unusual clinically significant Francisella strains","volume":"34","author":"Clarridge","year":"1996","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib8","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S1286-4579(03)00052-2","article-title":"Francisella novicida LPS has greater immunobiological activity in mice than F. tularensis LPS, and contributes to F. novicida murine pathogenesis","volume":"5","author":"Kieffer","year":"2003","journal-title":"Microbes Infect."},{"key":"10.1016\/j.micinf.2013.07.005_bib9","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/1471-2180-8-215","article-title":"Rapid dissemination of Francisella tularensis and the effect of route of infection","volume":"8","author":"Ojeda","year":"2008","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib10","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1189\/jlb.1208728","article-title":"Lethal pulmonary infection with Francisella novicida is associated with severe sepsis","volume":"86","author":"Sharma","year":"2009","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.micinf.2013.07.005_bib11","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1196\/annals.1409.000","article-title":"The Francisella pathogenicity island","volume":"1105","author":"Nano","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.micinf.2013.07.005_bib12","doi-asserted-by":"crossref","first-page":"6430","DOI":"10.1128\/JB.186.19.6430-6436.2004","article-title":"A Francisella tularensis pathogenicity island required for intramacrophage growth","volume":"186","author":"Nano","year":"2004","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micinf.2013.07.005_bib13","doi-asserted-by":"crossref","first-page":"3483","DOI":"10.1099\/mic.0.052308-0","article-title":"The biochemical properties of the Francisella pathogenicity island (FPI)-encoded proteins IglA, IglB, IglC, PdpB and DotU suggest roles in type VI secretion","volume":"157","author":"de Bruin","year":"2011","journal-title":"Microbiology"},{"key":"10.1016\/j.micinf.2013.07.005_bib14","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1093\/jmedent\/45.6.1108","article-title":"Francisella genes required for replication in mosquito cells","volume":"45","author":"Read","year":"2008","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.micinf.2013.07.005_bib15","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1099\/mic.0.025379-0","article-title":"Characterization of the pathogenicity island protein PdpA and its role in the virulence of Francisella novicida","volume":"155","author":"Schmerk","year":"2009","journal-title":"Microbiology"},{"key":"10.1016\/j.micinf.2013.07.005_bib16","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1099\/mic.0.025445-0","article-title":"A Francisella novicida pdpA mutant exhibits limited intracellular replication and remains associated with the lysosomal marker LAMP-1","volume":"155","author":"Schmerk","year":"2009","journal-title":"Microbiology"},{"key":"10.1016\/j.micinf.2013.07.005_bib17","doi-asserted-by":"crossref","first-page":"4584","DOI":"10.1128\/JB.00198-08","article-title":"The Francisella pathogenicity island protein PdpD is required for full virulence and associates with homologues of the type VI secretion system","volume":"190","author":"Ludu","year":"2008","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micinf.2013.07.005_bib18","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1196\/annals.1409.012","article-title":"Vaccines against Francisella tularensis","volume":"1105","author":"Conlan","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.micinf.2013.07.005_bib19","doi-asserted-by":"crossref","first-page":"2922","DOI":"10.1128\/iai.59.9.2922-2928.1991","article-title":"Live vaccine strain of Francisella tularensis: infection and immunity in mice","volume":"59","author":"Fortier","year":"1991","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib20","doi-asserted-by":"crossref","DOI":"10.1002\/0471142735.im1914s93","article-title":"Infection of mice with Francisella as an immunological model","volume":"93","author":"Conlan","year":"2011","journal-title":"Curr. Protoc. Immunol."},{"key":"10.1016\/j.micinf.2013.07.005_bib21","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1038\/nprot.2007.132","article-title":"Gene splicing and mutagenesis by PCR-driven overlap extension","volume":"2","author":"Heckman","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.micinf.2013.07.005_bib22","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.1128\/iai.62.8.3129-3137.1994","article-title":"Transfer of immunity against lethal murine Francisella infection by specific antibody depends on host gamma interferon and T cells","volume":"62","author":"Rhinehart-Jones","year":"1994","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/0471142735.im1425s93","article-title":"Measurement of macrophage-mediated killing of intracellular bacteria, including Francisella and Mycobacteria","volume":"93","author":"Elkins","year":"2011","journal-title":"Curr. Protoc. Immunol."},{"key":"10.1016\/j.micinf.2013.07.005_bib24","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1084\/jem.20030687","article-title":"Multiple T cell subsets control Francisella tularensis LVS intracellular growth without stimulation through macrophage interferon gamma receptors","volume":"198","author":"Cowley","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micinf.2013.07.005_bib25","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1084\/jem.20050569","article-title":"CD4\u2212CD8\u2212 T cells control intracellular bacterial infections both in\u00a0vitro and in\u00a0vivo","volume":"202","author":"Cowley","year":"2005","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micinf.2013.07.005_bib26","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1128\/IAI.69.1.194-203.2001","article-title":"Susceptibility to secondary Francisella tularensis LVS infection in B cell deficient mice is associated with neutrophilia but not with defects in specific T cell mediated immunity","volume":"69","author":"Bosio","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib27","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","article-title":"Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids","volume":"126","author":"Green","year":"1982","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.micinf.2013.07.005_bib28","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1111\/j.1365-2958.2009.06947.x","article-title":"The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence","volume":"74","author":"Barker","year":"2009","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib29","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1128\/JB.01759-08","article-title":"A conserved alpha-helix essential for a type VI secretion-like system of Francisella tularensis","volume":"191","author":"Broms","year":"2009","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micinf.2013.07.005_bib30","doi-asserted-by":"crossref","first-page":"3683","DOI":"10.1128\/IAI.01344-10","article-title":"IglG and IglI of the Francisella pathogenicity island are important virulence determinants of Francisella tularensis LVS","volume":"79","author":"Broms","year":"2011","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib31","doi-asserted-by":"crossref","first-page":"e34639","DOI":"10.1371\/journal.pone.0034639","article-title":"DotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicity","volume":"7","author":"Broms","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2013.07.005_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2180-7-1","article-title":"The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growth","volume":"7","author":"de Bruin","year":"2007","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib33","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1128\/IAI.00275-13","article-title":"Importance of PdpC, IglC, IglI, and IglG for modulation of a host cell death pathway induced by Francisella tularensis LVS","volume":"81","author":"Lindgren","year":"2013","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.micinf.2011.08.017","article-title":"Deletion of IglH in virulent Francisella tularensis subsp. holarctica FSC200 strain results in attenuation and provides protection against the challenge with the parental strain","volume":"14","author":"Straskova","year":"2012","journal-title":"Microbes Infect."},{"key":"10.1016\/j.micinf.2013.07.005_bib35","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3389\/fmicb.2013.00016","article-title":"Identification of Francisella novicida mutants that fail to induce prostaglandin E(2) synthesis by infected macrophages","volume":"4","author":"Woolard","year":"2013","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib36","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.micpath.2011.03.007","article-title":"Features of sepsis caused by pulmonary infection with Francisella tularensis Type A strain","volume":"51","author":"Sharma","year":"2011","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micinf.2013.07.005_bib37","doi-asserted-by":"crossref","first-page":"e1000459","DOI":"10.1371\/journal.ppat.1000459","article-title":"Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies","volume":"5","author":"Champion","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.micinf.2013.07.005_bib38","doi-asserted-by":"crossref","first-page":"e1000472","DOI":"10.1371\/journal.ppat.1000472","article-title":"Molecular evolutionary consequences of niche restriction in Francisella tularensis, a facultative intracellular pathogen","volume":"5","author":"Larsson","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.micinf.2013.07.005_bib39","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1196\/annals.1409.006","article-title":"The structure and function of Francisella lipopolysaccharide","volume":"1105","author":"Gunn","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.micinf.2013.07.005_bib40","doi-asserted-by":"crossref","first-page":"5843","DOI":"10.1128\/IAI.01176-08","article-title":"Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112","volume":"76","author":"Hall","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib41","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1574-6968.1997.tb10465.x","article-title":"Suppression of Francisella tularensis growth in the rat by co-infection with F. novicida","volume":"153","author":"Cowley","year":"1997","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.micinf.2013.07.005_bib42","doi-asserted-by":"crossref","first-page":"3291","DOI":"10.1128\/iai.59.9.3291-3296.1991","article-title":"Growth of Francisella spp. in rodent macrophages","volume":"59","author":"Anthony","year":"1991","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib43","doi-asserted-by":"crossref","first-page":"e9952","DOI":"10.1371\/journal.pone.0009952","article-title":"The Fischer 344 rat reflects human susceptibility to Francisella pulmonary challenge and provides a new platform for virulence and protection studies","volume":"5","author":"Ray","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2013.07.005_bib44","doi-asserted-by":"crossref","first-page":"4684","DOI":"10.1016\/j.vaccine.2009.05.060","article-title":"Vaccination of Fischer 344 rats against pulmonary infections by Francisella tularensis Type A strains","volume":"27","author":"Wu","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.micinf.2013.07.005_bib45","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.micpath.2004.04.005","article-title":"Mice sublethally infected with Francisella novicida U112 develop only marginal protective immunity against systemic or aerosol challenge with virulent Type A or B strains of F. tularensis","volume":"37","author":"Shen","year":"2004","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micinf.2013.07.005_bib46","doi-asserted-by":"crossref","first-page":"4314","DOI":"10.1128\/IAI.00654-09","article-title":"Vaccination with an attenuated strain of Francisella novicida prevents T-cell depletion and protects mice infected with the wild-type strain from severe sepsis","volume":"77","author":"Sharma","year":"2009","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib47","doi-asserted-by":"crossref","first-page":"5554","DOI":"10.1016\/j.vaccine.2009.07.034","article-title":"Vaccination with a defined Francisella tularensis subsp. novicida pathogenicity island mutant (\u0394iglB) induces protective immunity against homotypic and heterotypic challenge","volume":"27","author":"Cong","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.micinf.2013.07.005_bib48","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1128\/IAI.00036-12","article-title":"Perforin- and granzyme-mediated cytotoxic effector functions are essential for protection against Francisella tularensis following vaccination by the defined F. tularensis subsp. novicida DeltafopC vaccine strain","volume":"80","author":"Sanapala","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib49","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1128\/IAI.74.4.2063-2071.2006","article-title":"Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia","volume":"74","author":"Pammit","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib50","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/icb.2008.31","article-title":"CD4+ T cells are required during priming but not the effector phase of antibody-mediated IFN-gamma-dependent protective immunity against pulmonary Francisella novicida infection","volume":"86","author":"Powell","year":"2008","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.micinf.2013.07.005_bib51","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s10096-007-0434-x","article-title":"The presence of infectious extracellular Francisella tularensis subsp. novicida in murine plasma after pulmonary challenge","volume":"27","author":"Yu","year":"2008","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.micinf.2013.07.005_bib52","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.bbrc.2006.05.070","article-title":"In\u00a0vivo proteomic analysis of the intracellular bacterial pathogen, Francisella tularensis, isolated from mouse spleen","volume":"345","author":"Twine","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.micinf.2013.07.005_bib53","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.bbrc.2006.06.008","article-title":"Immunoproteomic analysis of the murine antibody response to successful and failed immunization with live anti-Francisella vaccines","volume":"346","author":"Twine","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.micinf.2013.07.005_bib54","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1471-2180-13-20","article-title":"The Francisella tularensis LVS \u0394pdpC mutant exhibits a unique phenotype during intracellular infection","volume":"13","author":"Lindgren","year":"2013","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micinf.2013.07.005_bib55","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1128\/IAI.00822-12","article-title":"Disruption of Francisella tularensis Schu S4 iglI, iglJ, and pdpC genes results in attenuation for growth in human macrophages and in\u00a0vivo virulence in mice and reveals a unique phenotype for pdpC","volume":"81","author":"Long","year":"2013","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib56","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1128\/IAI.00134-10","article-title":"Francisella tularensis \u0394pyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in\u00a0vivo","volume":"78","author":"Horzempa","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micinf.2013.07.005_bib57","doi-asserted-by":"crossref","first-page":"e61539","DOI":"10.1371\/journal.pone.0061539","article-title":"Identification of a live attenuated vaccine candidate for tularemia prophylaxis","volume":"8","author":"Mahawar","year":"2013","journal-title":"PLoS One"}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457913001470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457913001470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:33:17Z","timestamp":1761143597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457913001470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":57,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S1286457913001470"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2013.07.005","relation":{},"ISSN":["1286-4579"],"issn-type":[{"value":"1286-4579","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Generation of protection against Francisella novicida in mice depends on the pathogenicity protein PdpA, but not PdpC or PdpD","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2013.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Masson SAS","name":"copyright","label":"Copyright"}]}}