{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:33:55Z","timestamp":1790645635705,"version":"4.1.0"},"reference-count":132,"publisher":"Elsevier BV","issue":"9-10","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":1918,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GM007491"],"award-info":[{"award-number":["GM007491"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GM007288"],"award-info":[{"award-number":["GM007288"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI095094"],"award-info":[{"award-number":["AI095094"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.micinf.2017.12.003","type":"journal-article","created":{"date-parts":[[2017,12,26]],"date-time":"2017-12-26T13:04:04Z","timestamp":1514293444000},"page":"466-476","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Observations on bradyzoite biology"],"prefix":"10.1016","volume":"20","author":[{"given":"Vincent","family":"Tu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rama","family":"Yakubu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0357-7396","authenticated-orcid":false,"given":"Louis M.","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micinf.2017.12.003_bib1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.vetpar.2004.09.005","article-title":"Toxoplasmosis \u2013 a waterborne zoonosis","volume":"126","author":"Dubey","year":"2004","journal-title":"Vet Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib2","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0171-2985(99)80064-3","article-title":"Cell-mediated immunity to Toxoplasma gondii: initiation, regulation and effector function","volume":"201","author":"Yap","year":"1999","journal-title":"Immunobiology"},{"key":"10.1016\/j.micinf.2017.12.003_bib3","doi-asserted-by":"crossref","first-page":"3438","DOI":"10.4049\/jimmunol.145.10.3438","article-title":"Class I MHC genes and CD8+ T cells determine cyst number in Toxoplasma gondii infection","volume":"145","author":"Brown","year":"1990","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.micinf.2017.12.003_bib4","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.4049\/jimmunol.152.4.1856","article-title":"Antigen-specific CD8+ T cell clone protects against acute Toxoplasma gondii infection in mice","volume":"152","author":"Khan","year":"1994","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.micinf.2017.12.003_bib5","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/B978-0-444-53490-3.00008-X","article-title":"Toxoplasmosis","volume":"114","author":"Halonen","year":"2013","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.micinf.2017.12.003_bib6","doi-asserted-by":"crossref","first-page":"273","DOI":"10.2147\/DDDT.S60973","article-title":"Drugs in development for toxoplasmosis: advances, challenges, and current status","volume":"11","author":"Alday","year":"2017","journal-title":"Drug Des Dev Ther"},{"key":"10.1016\/j.micinf.2017.12.003_bib7","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.biopha.2016.05.041","article-title":"Human toxoplasmosis \u2013 searching for novel chemotherapeutics","volume":"82","author":"Antczak","year":"2016","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.micinf.2017.12.003_bib8","doi-asserted-by":"crossref","first-page":"3994","DOI":"10.1093\/nar\/gki709","article-title":"Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains","volume":"33","author":"Balaji","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.micinf.2017.12.003_bib9","doi-asserted-by":"crossref","first-page":"e1000852","DOI":"10.1371\/journal.pcbi.1000852","article-title":"The construction and use of log-odds substitution scores for multiple sequence alignment","volume":"6","author":"Altschul","year":"2010","journal-title":"PLoS Comput Biol"},{"key":"10.1016\/j.micinf.2017.12.003_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0012354","article-title":"Coordinated progression through two subtranscriptomes underlies the tachyzoite cycle of Toxoplasma gondii","volume":"5","author":"Behnke","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2017.12.003_bib11","doi-asserted-by":"crossref","first-page":"6871","DOI":"10.1073\/pnas.1300059110","article-title":"ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst","volume":"110","author":"Radke","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.micinf.2017.12.003_bib12","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00347-16","volume":"2","author":"Hong","year":"2017","journal-title":"mSphere"},{"key":"10.1016\/j.micinf.2017.12.003_bib13","series-title":"mSphere","article-title":"Toxoplasma gondii AP2IX-4 regulates gene expression during Bradyzoite development","volume":"vol. 2","author":"Huang","year":"2017"},{"key":"10.1016\/j.micinf.2017.12.003_bib14","first-page":"1","article-title":"Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosis","author":"Radke","year":"2017","journal-title":"bioRxiv"},{"key":"10.1016\/j.micinf.2017.12.003_bib15","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/mmi.12121","article-title":"The Toxoplasma nuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation","volume":"87","author":"Walker","year":"2013","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib16","doi-asserted-by":"crossref","first-page":"21661","DOI":"10.1074\/jbc.272.35.21661","article-title":"Translational regulation of yeast GCN4: a window on factors that control initiator-tRNA binding to the ribosome","volume":"272","author":"Hinnebusch","year":"1997","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.micinf.2017.12.003_bib17","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1042\/bj20040262","article-title":"Parasite-specific eIF2 (eukaryotic initiation factor-2) kinase required for stress-induced translation control","volume":"380","author":"Sullivan","year":"2004","journal-title":"Biochem J"},{"key":"10.1016\/j.micinf.2017.12.003_bib18","doi-asserted-by":"crossref","first-page":"16591","DOI":"10.1074\/jbc.M800681200","article-title":"Translation regulation by eukaryotic initiation factor-2 kinases in the development of latent cysts in Toxoplasma gondii","volume":"283","author":"Narasimhan","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1016\/j.micinf.2017.12.003_bib19","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1128\/EC.05117-11","article-title":"A\u00a0GCN2-Like eukaryotic initiation factor 2 kinase increases the viability of extracellular Toxoplasma gondii parasites","volume":"10","author":"Konrad","year":"2011","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.micinf.2017.12.003_bib20","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1128\/EC.00021-13","article-title":"The unfolded protein response in the protozoan parasite Toxoplasma gondii features translational and transcriptional control","volume":"12","author":"Joyce","year":"2013","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.micinf.2017.12.003_bib21","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1128\/AAC.01899-12","article-title":"Inhibitors of eIF2\u03b1 dephosphorylation slow replication and stabilize latency in Toxoplasma gondii","volume":"57","author":"Konrad","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.micinf.2017.12.003_bib22","doi-asserted-by":"crossref","first-page":"5077","DOI":"10.1111\/febs.13048","article-title":"Sustained translational repression of lactate dehydrogenase 1 in Toxoplasma gondii bradyzoites is conferred by a small regulatory RNA hairpin","volume":"281","author":"Holmes","year":"2014","journal-title":"FEBS J"},{"key":"10.1016\/j.micinf.2017.12.003_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.ppat.1000920","article-title":"A complex small RNA repertoire is generated by a plant\/fungal-like machinery and effected by a metazoan-like argonaute in the single-cell human parasite Toxoplasma gondii","volume":"6","author":"Braun","year":"2010","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.micinf.2017.12.003_bib24","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.molbiopara.2013.03.003","article-title":"Evidence of tRNA cleavage in apicomplexan parasites: half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei","volume":"188","author":"Galizi","year":"2013","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib25","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/1756-3305-7-141","article-title":"Characterization of TgPuf1, a member of the Puf family RNA-binding proteins from Toxoplasma gondii","volume":"7","author":"Liu","year":"2014","journal-title":"Parasit Vectors"},{"key":"10.1016\/j.micinf.2017.12.003_bib26","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.jmb.2013.01.039","article-title":"Toxoplasma gondii Alba proteins are involved in translational control of gene expression","volume":"425","author":"Gissot","year":"2013","journal-title":"J Mol Biol"},{"key":"10.1016\/j.micinf.2017.12.003_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0019860","article-title":"The Puf-family RNA-binding protein Puf2 controls sporozoite conversion to liver stages in the malaria parasite","volume":"6","author":"M\u00fcller","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2017.12.003_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002046","article-title":"Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio","volume":"7","author":"Gomes-Santos","year":"2011","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.micinf.2017.12.003_bib29","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.gene.2014.04.011","article-title":"Characterization of a homolog of DEAD-box RNA helicases in Toxoplasma gondii as a marker of cytoplasmic mRNP stress granules","volume":"543","author":"Cherry","year":"2014","journal-title":"Gene"},{"key":"10.1016\/j.micinf.2017.12.003_bib30","first-page":"1","article-title":"Translational control in the latency of apicomplexan parasites","volume":"xx","author":"Holmes","year":"2017","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib31","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00755-16","article-title":"Toxoplasma gondii cyclic AMP-dependent protein kinase subunit 3 is involved in the switch from tachyzoite to Bradyzoite development","volume":"7","author":"Sugi","year":"2016","journal-title":"mBio"},{"key":"10.1016\/j.micinf.2017.12.003_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0022492","article-title":"Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth","volume":"6","author":"Kurokawa","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2017.12.003_bib33","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ijpara.2005.08.014","article-title":"Cyclic nucleotide kinases and tachyzoite\u2013bradyzoite transition in Toxoplasma gondii","volume":"36","author":"Eaton","year":"2006","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib34","doi-asserted-by":"crossref","first-page":"6361","DOI":"10.1128\/AAC.01236-15","article-title":"In vitro and in vivo effects of the bumped kinase inhibitor 1294 in the related cyst-forming apicomplexans Toxoplasma gondii and Neospora caninum","volume":"59","author":"Winzer","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.micinf.2017.12.003_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpddr.2014.12.001","article-title":"A\u00a0single mutation in the gatekeeper residue in TgMAPKL-1 restores the inhibitory effect of a bumped kinase inhibitor on the cell cycle","volume":"5","author":"Sugi","year":"2015","journal-title":"Int J Parasitol Drugs Drug Resist"},{"key":"10.1016\/j.micinf.2017.12.003_bib36","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s00436-015-4807-2","article-title":"Deletion of mitogen-activated protein kinase 1 inhibits development and growth of Toxoplasma gondii","volume":"115","author":"Cao","year":"2016","journal-title":"Parasitol Res"},{"key":"10.1016\/j.micinf.2017.12.003_bib37","first-page":"1","article-title":"Secreted protein kinases regulate cyst burden during chronic toxoplasmosis","author":"Jones","year":"2016","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib38","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1186\/1471-2164-15-806","article-title":"Dual transcriptional profiling of mice and Toxoplasma gondii during acute and chronic infection","volume":"15","author":"Pittman","year":"2014","journal-title":"BMC Genomics"},{"key":"10.1016\/j.micinf.2017.12.003_bib39","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1146\/annurev-micro-091014-104353","article-title":"Genetic mapping of pathogenesis determinants in Toxoplasma gondii","volume":"70","author":"Behnke","year":"2016","journal-title":"Annu Rev Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib40","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00193-16","article-title":"The Toxoplasma gondii rhoptry kinome is essential for chronic infection","volume":"7","author":"Fox","year":"2016","journal-title":"mBio"},{"key":"10.1016\/j.micinf.2017.12.003_bib41","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ijpara.2008.10.003","article-title":"Proteomes and transcriptomes of the Apicomplexa \u2013 where's the message?","volume":"39","author":"Wastling","year":"2009","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib42","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2008-9-7-r116","article-title":"The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation","volume":"9","author":"Xia","year":"2008","journal-title":"Genome Biol"},{"key":"10.1016\/j.micinf.2017.12.003_bib43","first-page":"2797","article-title":"Posttranslational modifications as key regulators of apicomplexan biology: insights from proteome-wide studies","author":"Yakubu","year":"2017","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib44","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1574-6968.1996.tb08090.x","article-title":"Enzymes of energy metabolism in the bradyzoites and tachyzoites of Toxoplasma gondii","volume":"137","author":"Denton","year":"1996","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.micinf.2017.12.003_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1119(96)00566-5","article-title":"Toxoplasma gondii expresses two distinct lactate dehydrogenase homologous genes during its life cycle in intermediate hosts","volume":"184","author":"Yang","year":"1997","journal-title":"Gene"},{"key":"10.1016\/j.micinf.2017.12.003_bib46","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1741-7007-3-26","article-title":"The transcriptome of Toxoplasma gondii","volume":"3","author":"Radke","year":"2005","journal-title":"BMC Biol"},{"key":"10.1016\/j.micinf.2017.12.003_bib47","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1128\/EC.05182-11","article-title":"Identification of tissue cyst wall components by transcriptome analysis of in vivo and in vitro Toxoplasma gondii bradyzoites","volume":"10","author":"Buchholz","year":"2011","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.micinf.2017.12.003_bib48","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0166-6851(01)00360-7","article-title":"The kinetic properties and sensitivities to inhibitors of lactate dehydrogenases (LDH1 and LDH2) from <i>Toxoplasma gondii<\/i>: comparisons with pLDH from Plasmodium falciparum","volume":"118","author":"Dando","year":"2001","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib49","first-page":"12","article-title":"Lactate dehydrogenase in Toxoplasma gondii controls virulence, bradyzoite differentiation, and chronic infection","author":"Abdelbaset","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2017.12.003_bib50","doi-asserted-by":"crossref","first-page":"52300","DOI":"10.1074\/jbc.M409175200","article-title":"The expression of lactate dehydrogenase is important for the cell cycle of Toxoplasma gondii","volume":"279","author":"Al-Anouti","year":"2004","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.micinf.2017.12.003_bib51","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.exppara.2009.01.016","article-title":"Toxoplasma gondii: over-expression of lactate dehydrogenase enhances differentiation under alkaline conditions","volume":"122","author":"Liwak","year":"2009","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib52","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1006\/jmbi.2001.4730","article-title":"Differential expression of two plant-like enolases with distinct enzymatic and antigenic properties during stage conversion of the protozoan parasite Toxoplasma gondii","volume":"309","author":"Dzierszinski","year":"2001","journal-title":"J\u00a0Mol Biol"},{"key":"10.1016\/j.micinf.2017.12.003_bib53","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0105820","article-title":"Nuclear glycolytic enzyme enolase of Toxoplasma gondii functions as a transcriptional regulator","volume":"9","author":"Mouveaux","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2017.12.003_bib54","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/S0020-7519(02)00129-7","article-title":"Evidence for nuclear localisation of two stage-specific isoenzymes of enolase in Toxoplasma gondii correlates with active parasite replication","volume":"32","author":"Ferguson","year":"2002","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib55","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1107\/S1399004714026479","article-title":"The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions","volume":"71","author":"Ruan","year":"2015","journal-title":"Acta Crystallogr Sect D Biol Crystallogr"},{"key":"10.1016\/j.micinf.2017.12.003_bib56","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1093\/nar\/gki314","article-title":"Transcriptional regulation of two stage-specifically expressed genes in the protozoan parasite Toxoplasma gondi","volume":"33","author":"Kibe","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.micinf.2017.12.003_bib57","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1111\/mmi.12999","article-title":"Expression of the glycolytic enzymes enolase and lactate dehydrogenase during the early phase of Toxoplasma differentiation is regulated by an intron retention mechanism","volume":"96","author":"Lunghi","year":"2015","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib58","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1111\/j.1365-2958.1995.tb02344.x","article-title":"Cloning and characterization of a bradyzoite-specifically expressed gene (hsp30\/bag1) of Toxoplasma gondii, related to genes encoding small heat-shock proteins of plants","volume":"16","author":"Bohne","year":"1995","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib59","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.ijpara.2003.11.024","article-title":"Use of molecular and ultrastructural markers to evaluate stage conversion of Toxoplasma gondii in both the intermediate and definitive host","volume":"34","author":"Ferguson","year":"2004","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.ppat.1003823","article-title":"The Toxoplasma gondii cyst wall protein CST1 is critical for cyst wall integrity and promotes bradyzoite persistence","volume":"9","author":"Tomita","year":"2013","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.micinf.2017.12.003_bib61","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1046\/j.1365-2958.1999.01210.x","article-title":"Disruption of the Toxoplasma gondii bradyzoite-specific gene BAG1 decreases in\u00a0vivo cyst formation","volume":"31","author":"Zhang","year":"1999","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib62","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0166-6851(97)00087-X","article-title":"Stage-specific expression of a selectable marker in Toxoplasma gondii permits selective inhibition of either tachyzoites or bradyzoites","volume":"88","author":"Bohne","year":"1997","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib63","doi-asserted-by":"crossref","first-page":"e0178203","DOI":"10.1371\/journal.pone.0178203","volume":"12","author":"Murata","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2017.12.003_bib64","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1111\/j.1365-2958.2008.06249.x","article-title":"The transcription of bradyzoite genes in Toxoplasma gondii is controlled by autonomous promoter elements","volume":"68","author":"Behnke","year":"2008","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib65","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1046\/j.1365-2958.2002.02903.x","article-title":"Genetic analysis of tachyzoite to bradyzoite differentiation mutants in Toxoplasma gondii reveals a hierarchy of gene induction","volume":"44","author":"Singh","year":"2002","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib66","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0166-6851(00)00324-8","article-title":"Molecular cloning, organellar targeting and developmental expression of mitochondrial chaperone HSP60 in Toxoplasma gondii","volume":"111","author":"Toursel","year":"2000","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib67","doi-asserted-by":"crossref","first-page":"3295","DOI":"10.1128\/IAI.66.7.3295-3302.1998","article-title":"Bradyzoite development in Toxoplasma gondii and the hsp70 stress response","volume":"66","author":"Weiss","year":"1998","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2017.12.003_bib68","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s12539-015-0107-x","article-title":"Targeting heat shock proteins 60 and 70 of Toxoplasma gondii as a potential drug target: in silico approach","volume":"8","author":"Ashwinder","year":"2016","journal-title":"Interdiscipl Sci Comput Life Sci"},{"key":"10.1016\/j.micinf.2017.12.003_bib69","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.jmb.2005.05.031","article-title":"Toxoplasma gondii Hsp90 is a potential drug target whose expression and subcellular localization are developmentally regulated","volume":"350","author":"Echeverria","year":"2005","journal-title":"J Mol Biol"},{"key":"10.1016\/j.micinf.2017.12.003_bib70","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1051\/parasite\/2017023","article-title":"The heat shock protein 90 of Toxoplasma gondii is essential for invasion of host cells and tachyzoite growth","volume":"24","author":"Sun","year":"2017","journal-title":"Parasite"},{"key":"10.1016\/j.micinf.2017.12.003_bib71","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.exppara.2011.01.015","article-title":"Toxoplasma gondii: a bradyzoite-specific DnaK-tetratricopeptide repeat (DnaK-TPR) protein interacts with p23 co-chaperone protein","volume":"127","author":"Ueno","year":"2011","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib72","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/S0020-7519(01)00261-2","article-title":"Surface antigens of Toxoplasma gondii: variations on a theme","volume":"31","author":"Lekutis","year":"2001","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib73","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.4049\/jimmunol.141.10.3584","article-title":"Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii","volume":"141","author":"Burg","year":"1988","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.micinf.2017.12.003_bib74","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0166-6851(96)02740-5","article-title":"Molecular cloning of the Toxoplasma gondii sag4 gene encoding an 18 kDa bradyzoite specific surface protein","volume":"82","author":"Odberg-Ferragut","year":"1996","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib75","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.1128\/iai.59.10.3750-3753.1991","article-title":"Characterization of bradyzoite-specific antigens of Toxoplasma gondii","volume":"59","author":"Tomavo","year":"1991","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2017.12.003_bib76","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1006\/expr.2000.4556","article-title":"Toxoplasma gondii: identification of a developmentally regulated family of genes related to SAG2","volume":"96","author":"Lekutis","year":"2000","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib77","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1128\/IAI.01494-07","article-title":"A\u00a0cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence","volume":"76","author":"Saeij","year":"2008","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2017.12.003_bib78","first-page":"329","article-title":"Toxoplasma gondii asexual development: identification of developmentally regulated genes and distinct patterns of gene expression","volume":"1","author":"Cleary","year":"2002","journal-title":"Society"},{"key":"10.1016\/j.micinf.2017.12.003_bib79","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0166-6851(00)00361-3","article-title":"Bradyzoite-specific expression of a P-type ATPase in Toxoplasma gondii","volume":"112","author":"Holpert","year":"2001","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib80","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1128\/MCB.18.2.807","article-title":"Isolation of developmentally regulated genes from Toxoplasma gondii by a gene trap with the positive and negative selectable marker hypoxanthine\u2013xanthine\u2013guanine phosphoribosyltransferase","volume":"18","author":"Knoll","year":"1998","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.micinf.2017.12.003_bib81","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.ijpara.2007.02.001","article-title":"The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognised by the P36 monoclonal antibody is SRS9","volume":"37","author":"Van","year":"2007","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib82","doi-asserted-by":"crossref","first-page":"9192","DOI":"10.1074\/jbc.M808714200","article-title":"Structural characterization of the bradyzoite surface antigen (BSR4) from Toxoplasma gondii, a unique addition to the surface antigen glycoprotein 1-related superfamily","volume":"284","author":"Crawford","year":"2009","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.micinf.2017.12.003_bib83","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1128\/IAI.01862-06","article-title":"Bradyzoite-specific surface antigen SRS9 plays a role in maintaining Toxoplasma gondii persistence in the brain and in host control of parasite replication in the intestine","volume":"75","author":"Kim","year":"2007","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2017.12.003_bib84","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.molbiopara.2005.11.004","article-title":"Disruption of the bradyzoite-specific P-type (H+)-ATPase PMA1 in Toxoplasma gondii leads to decreased bradyzoite differentiation after stress stimuli but does not interfere with mature tissue cyst formation","volume":"146","author":"Holpert","year":"2006","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib85","doi-asserted-by":"crossref","first-page":"29252","DOI":"10.1016\/S0021-9258(19)62038-7","article-title":"Tandemly repeated genes encode nucleoside triphosphate hydrolase isoforms secreted into the parasitophorous vacuole of Toxoplasma gondii","volume":"269","author":"Bermudes","year":"1994","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.micinf.2017.12.003_bib86","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1006\/expr.1998.4384","article-title":"The expression and distribution of dense granule proteins in the enteric (Coccidian) forms of Toxoplasma gondii in the small intestine of the cat","volume":"91","author":"Ferguson","year":"1999","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib87","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.molbiopara.2005.08.011","article-title":"A\u00a0novel rhoptry protein in Toxoplasma gondii bradyzoites and merozoites","volume":"144","author":"Schwarz","year":"2005","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib88","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.molbiopara.2007.10.005","article-title":"Identification of novel bradyzoite-specific Toxoplasma gondii genes with domains for protein\u2013protein interactions by suppression subtractive hybridization","volume":"157","author":"Friesen","year":"2008","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib89","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/(SICI)1521-1878(199911)21:11<932::AID-BIES5>3.0.CO;2-N","article-title":"The tetratricopeptide repeat: a structural motif mediating protein\u2013protein interactions","volume":"21","author":"Blatch","year":"1999","journal-title":"Bioessays"},{"key":"10.1016\/j.micinf.2017.12.003_bib90","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0968-0004(91)90070-C","article-title":"The TPR snap helix: a novel protein repeat motif from mitosis to transcription","volume":"16","author":"Goebl","year":"1991","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.micinf.2017.12.003_bib91","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.tibs.2003.10.007","article-title":"TPR proteins: the versatile helix","volume":"28","author":"D'Andrea","year":"2003","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.micinf.2017.12.003_bib92","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1186\/1471-2164-14-467","article-title":"Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains","volume":"14","author":"Yang","year":"2013","journal-title":"BMC Genom"},{"key":"10.1016\/j.micinf.2017.12.003_bib93","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.exppara.2008.09.018","article-title":"Toxoplasma gondii: identification and characterization of bradyzoite-specific deoxyribose phosphate aldolase-like gene (TgDPA)","volume":"121","author":"Ueno","year":"2009","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib94","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.molbiopara.2010.04.007","article-title":"Toxoplasma gondii deoxyribose phosphate aldolase-like protein (TgDPA) interacts with actin depolymerizing factor (TgADF) to enhance the actin filament dynamics in the bradyzoite stage","volume":"173","author":"Ueno","year":"2010","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib95","first-page":"1","article-title":"Proteomic differences between developmental stages of Toxoplasma gondii revealed by iTRAQ-based quantitative proteomics","volume":"8","author":"Wang","year":"2017","journal-title":"Front Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib96","doi-asserted-by":"crossref","first-page":"D391","DOI":"10.2741\/Weiss","article-title":"The development and biology of bradyzoites of Toxoplasma gondii","volume":"5","author":"Weiss","year":"2000","journal-title":"Front Biosci"},{"key":"10.1016\/j.micinf.2017.12.003_bib97","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1091\/mbc.01-06-0309","article-title":"Daughter cell assembly in the Protozoan parasite Toxoplasma gondii","volume":"13","author":"Hu","year":"2002","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.micinf.2017.12.003_bib98","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0166-6851(03)00198-1","article-title":"A\u00a0change in the premitotic period of the cell cycle is associated with bradyzoite differentiation in Toxoplasma gondii","volume":"131","author":"Radke","year":"2003","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib99","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1128\/iai.62.5.1761-1767.1994","article-title":"Reduced replication of Toxoplasma gondii is necessary for induction of bradyzoite-specific antigens: a possible role for nitric oxide in triggering stage conversion","volume":"62","author":"Bohne","year":"1994","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2017.12.003_bib100","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.ijpara.2008.06.004","article-title":"The cell cycle and Toxoplasma gondii cell division: tightly knit or loosely stitched?","volume":"38","author":"Gubbels","year":"2008","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib101","first-page":"1","article-title":"Novel approaches reveal that Toxoplasma gondii bradyzoites within tissue cysts are dynamic and replicating entities In","volume":"6","author":"Watts","year":"2015","journal-title":"Vivo"},{"key":"10.1016\/j.micinf.2017.12.003_bib102","doi-asserted-by":"crossref","first-page":"15710","DOI":"10.1038\/ncomms15710","article-title":"Myosin-dependent cell\u2013cell communication controls synchronicity of division in acute and chronic stages of Toxoplasma gondii","volume":"8","author":"Fr\u00e9nal","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.micinf.2017.12.003_bib103","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.micinf.2004.09.007","article-title":"Amylopectin biogenesis and characterization in the protozoan parasite Toxoplasma gondii, the intracellular development of which is restricted in the HepG2 cell line","volume":"7","author":"Gu\u00e9rardel","year":"2005","journal-title":"Microb Infect"},{"key":"10.1016\/j.micinf.2017.12.003_bib104","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s00239-004-0185-6","article-title":"Evolution of plant-like crystalline storage polysaccharide in the protozoan parasite Toxoplasma gondii argues for a red alga ancestry","volume":"60","author":"Coppin","year":"2005","journal-title":"J Mol Evol"},{"key":"10.1016\/j.micinf.2017.12.003_bib105","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.chom.2015.11.004","article-title":"Regulation of starch stores by a Ca2+-Dependent protein kinase is essential for viable cyst development in Toxoplasma gondii","volume":"18","author":"Uboldi","year":"2015","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.micinf.2017.12.003_bib106","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01289-17","volume":"8","author":"Sugi","year":"2017","journal-title":"mBio"},{"key":"10.1016\/j.micinf.2017.12.003_bib107","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1002\/pro.5560031011","article-title":"Electrostatic effects in the control of glycogen phosphorylase by phosphorylation","volume":"3","author":"Johnson","year":"1994","journal-title":"Protein Sci"},{"key":"10.1016\/j.micinf.2017.12.003_bib108","doi-asserted-by":"crossref","first-page":"26833","DOI":"10.1074\/jbc.270.45.26833","article-title":"Mechanism of regulation in yeast glycogen phosphorylase","volume":"270","author":"Lin","year":"1995","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.micinf.2017.12.003_bib109","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1128\/EC.3.4.992-1003.2004","article-title":"Dynamics of Toxoplasma gondii differentiation","volume":"3","author":"Dzierszinski","year":"2004","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.micinf.2017.12.003_bib110","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00755-16","article-title":"Toxoplasma gondii cyclic AMP-dependent protein kinase subunit 3 is involved in the switch from tachyzoite to bradyzoite development","volume":"7","author":"Sugi","year":"2016","journal-title":"mBio"},{"key":"10.1016\/j.micinf.2017.12.003_bib111","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/s00436-015-4791-6","article-title":"Evaluation of the basic functions of six calcium-dependent protein kinases in Toxoplasma gondii using CRISPR-Cas9 system","volume":"115","author":"Wang","year":"2016","journal-title":"Parasitol Res"},{"key":"10.1016\/j.micinf.2017.12.003_bib112","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1128\/IAI.01173-15","article-title":"Analysis of noncanonical calcium-dependent protein kinases in Toxoplasma gondii by targeted gene deletion using CRISPR\/Cas9","volume":"84","author":"Long","year":"2016","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2017.12.003_bib113","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1111\/j.1462-5822.2011.01681.x","article-title":"The organization of the wall filaments and characterization of the matrix structures of Toxoplasma gondii cyst form","volume":"13","author":"Lemgruber","year":"2011","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.micinf.2017.12.003_bib114","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1128\/CMR.11.2.267","article-title":"Structures of Toxoplasma gondii tachyzoites, bradyzoites, and sporozoites and biology and development of tissue cysts","volume":"11","author":"Dubey","year":"1998","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.micinf.2017.12.003_bib115","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1073\/pnas.91.2.509","article-title":"The parasitophorous vacuole membrane surrounding intracellular Toxoplasma gondii functions as a molecular sieve","volume":"91","author":"Schwab","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.micinf.2017.12.003_bib116","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.2307\/3279850","article-title":"Search for the presence of lectin-binding sites on Toxoplasma gondii","volume":"63","author":"Sethi","year":"1977","journal-title":"J\u00a0Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib117","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1098\/rstb.1997.0119","article-title":"Genetic and biochemical analysis of development in Toxoplasma gondii","volume":"352","author":"Boothroyd","year":"1997","journal-title":"Philos Trans R Soc B Biol Sci"},{"key":"10.1016\/j.micinf.2017.12.003_bib118","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02048-16","volume":"8","author":"Tomita","year":"2017","journal-title":"mBio"},{"key":"10.1016\/j.micinf.2017.12.003_bib119","first-page":"9","article-title":"A\u00a0nucleotide sugar transporter involved in glycosylation of the toxoplasma tissue cyst wall is required for efficient persistence of bradyzoites","author":"Caffaro","year":"2013","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.micinf.2017.12.003_bib120","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1128\/IAI.69.1.501-507.2001","article-title":"Initial characterization of CST1, a Toxoplasma gondii cyst wall glycoprotein","volume":"69","author":"Zhang","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2017.12.003_bib121","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1006\/expr.1993.1056","article-title":"Toxoplasma gondii: differential location of antigens secreted from encysted bradyzoites","volume":"77","author":"Torpier","year":"1993","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib122","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.pt.2014.12.002","article-title":"Toxoplasma secretory granules: one population or more?","volume":"31","author":"Mercier","year":"2015","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib123","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1091\/mbc.e02-01-0021","article-title":"Biogenesis of nanotubular network in Toxoplasma parasitophorous vacuole induced by parasite proteins","volume":"13","author":"Mercier","year":"2002","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.micinf.2017.12.003_bib124","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/s004360050123","article-title":"Toxoplasma gondii: appearance of specific markers during the development of tissue cysts in\u00a0vitro","volume":"82","author":"Lane","year":"1996","journal-title":"Parasitol Res"},{"key":"10.1016\/j.micinf.2017.12.003_bib125","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0169-4758(94)90078-7","article-title":"Dense-granule organelles of Toxoplasma gondii: their role in the host\u2013parasite relationship","volume":"10","author":"Cesbron-Delauw","year":"1994","journal-title":"Parasitol Today"},{"key":"10.1016\/j.micinf.2017.12.003_bib126","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1128\/EC.00297-10","article-title":"Type II Toxoplasma gondii KU80 knockout strains enable functional analysis of genes required for cyst development and latent infection","volume":"10","author":"Fox","year":"2011","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.micinf.2017.12.003_bib127","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0120331","article-title":"Yeast three-hybrid screen identifies TgBRADIN\/GRA24 as a negative regulator of Toxoplasma gondii bradyzoite differentiation","volume":"10","author":"Odell","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.micinf.2017.12.003_bib128","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005211","article-title":"Fundamental roles of the Golgi-associated Toxoplasma aspartyl protease, ASP5, at the host-parasite interface","volume":"11","author":"Hammoudi","year":"2015","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.micinf.2017.12.003_bib129","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1128\/EC.00343-12","article-title":"Bradyzoite pseudokinase 1 is crucial for efficient oral infectivity of the Toxoplasma gondii tissue cyst","volume":"12","author":"Buchholz","year":"2013","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.micinf.2017.12.003_bib130","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0166-6851(94)90155-4","article-title":"Molecular characterization of a 65-kilodalton Toxoplasma gondii antigen expressed abundantly in the matrix of tissue cysts","volume":"66","author":"Parmley","year":"1994","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib131","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.molbiopara.2009.10.006","article-title":"Isolation of Toxoplasma gondii development mutants identifies a potential proteophosphogylcan that enhances cyst wall formation","volume":"169","author":"Craver","year":"2010","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.micinf.2017.12.003_bib132","first-page":"1","article-title":"Developmental change in translation initiation alters the localization of a common microbial protein necessary for Toxoplasma chronic infection","volume":"0","author":"Milligan-Myhre","year":"2016","journal-title":"Mol Microbiol"}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457917302253?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457917302253?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:37:19Z","timestamp":1761143839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457917302253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":132,"journal-issue":{"issue":"9-10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S1286457917302253"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2017.12.003","relation":{},"ISSN":["1286-4579"],"issn-type":[{"value":"1286-4579","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Observations on bradyzoite biology","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2017.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Masson SAS on behalf of Institut Pasteur.","name":"copyright","label":"Copyright"}]}}