{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:39:09Z","timestamp":1784547549286,"version":"3.55.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":1095,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100007320","name":"Instituto Nacional de Ci\u00eancia e Tecnologia de Matem\u00e1tica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007320","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005285","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Goi\u00e1s","doi-asserted-by":"publisher","award":["201810267000022"],"award-info":[{"award-number":["201810267000022"]}],"id":[{"id":"10.13039\/501100005285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbes and Infection"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.micinf.2020.09.008","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T12:07:39Z","timestamp":1601294859000},"page":"104762","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Comparative proteomics in the three major human pathogenic species of the genus Sporothrix"],"prefix":"10.1016","volume":"23","author":[{"given":"Mirelle Garcia","family":"Silva-Bail\u00e3o","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia de Sousa","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoel Marques Evangelista","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00e3 Cardoso","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Almeida-Paes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clayton Luiz","family":"Borges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre Melo","family":"Bail\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2518-7575","authenticated-orcid":false,"given":"Alexandre Siqueira Guedes","family":"Coelho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9lia Maria de Almeida","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosely Maria","family":"Zancop\u00e9-Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micinf.2020.09.008_bib1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s12281-015-0237-y","article-title":"Epidemiological aspects of sporotrichosis epidemic in Brazil","volume":"9","author":"Gutierrez-Galhardo","year":"2015","journal-title":"Current Fungal Infect Rep"},{"key":"10.1016\/j.micinf.2020.09.008_bib2","doi-asserted-by":"crossref","first-page":"621","DOI":"10.3201\/eid2603.190803","article-title":"Geographic expansion of sporotrichosis, Brazil","volume":"26","author":"Gremi\u00e3o","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.micinf.2020.09.008_bib3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1540-9740.2007.06683.x","article-title":"A\u00a0rose by any other name","volume":"6","author":"Engle","year":"2007","journal-title":"Skinmed"},{"key":"10.1016\/j.micinf.2020.09.008_bib4","doi-asserted-by":"crossref","DOI":"10.1007\/s11046-020-00425-0","article-title":"The threat of emerging and re-emerging pathogenic Sporothrix species","author":"Rodrigues","year":"2020","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micinf.2020.09.008_bib5","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1590\/abd1806-4841.2017279","article-title":"Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics","volume":"92","author":"Orofino-Costa","year":"2017","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.micinf.2020.09.008_bib6","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1590\/abd1806-4841.20164859","article-title":"Disseminated cutaneous sporotrichosis associated with ocular lesion in an immunocompetent patient","volume":"91","author":"Medeiros","year":"2016","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.micinf.2020.09.008_bib7","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1007\/s11046-017-0197-6","article-title":"Cavitary pulmonary sporotrichosis: case report and literature review","volume":"182","author":"Rojas","year":"2017","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micinf.2020.09.008_bib8","article-title":"Central nervous system infection with other endemic mycoses: rare manifestation of blastomycosis, paracoccidioidomycosis, talaromycosis, and sporotrichosis","volume":"5","author":"Kauffman","year":"2019","journal-title":"J\u00a0Fungi (Basel)"},{"key":"10.1016\/j.micinf.2020.09.008_bib9","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/mmy\/myz024","article-title":"Zoonotic sporotrichosis with greater severity in Rio de Janeiro, Brazil: 118 hospitalizations and 11 deaths in the last 2 decades in a reference institution","volume":"58","author":"Falc\u00e3o","year":"2020","journal-title":"Med Mycol"},{"key":"10.1016\/j.micinf.2020.09.008_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11046-009-9190-z","article-title":"Current research on the immune response to experimental sporotrichosis","volume":"168","author":"Carlos","year":"2009","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micinf.2020.09.008_bib11","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1469-0691.2009.02824.x","article-title":"Different virulence levels of the species of Sporothrix in a murine model","volume":"15","author":"Arrillaga-Moncrieff","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.micinf.2020.09.008_bib12","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003094","article-title":"Sporotrichosis in Rio de Janeiro, Brazil: Sporothrix brasiliensis is associated with atypical clinical presentations","volume":"8","author":"Almeida-Paes","year":"2014","journal-title":"PLoS Neglected Trop Dis"},{"key":"10.1016\/j.micinf.2020.09.008_bib13","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1093\/mmy\/myx103","article-title":"Sporotrichosis between 1898 and 2017: the evolution of knowledge on a changeable disease and on emerging etiological agents","volume":"56","author":"Lopes-Bezerra","year":"2018","journal-title":"Med Mycol"},{"key":"10.1016\/j.micinf.2020.09.008_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11046-011-9456-0","article-title":"Protein profiling of the dimorphic pathogenic fungus, Sporothrix schenckii","volume":"173","author":"Zhang","year":"2012","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micinf.2020.09.008_bib15","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jprot.2014.11.013","article-title":"Immunoproteomic analysis reveals a convergent humoral response signature in the Sporothrix schenckii complex","volume":"115","author":"Rodrigues","year":"2015","journal-title":"J\u00a0Proteomics"},{"key":"10.1016\/j.micinf.2020.09.008_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004016","article-title":"Proteomics-based characterization of the humoral immune response in sporotrichosis: toward discovery of potential diagnostic and vaccine antigens","volume":"9","author":"Rodrigues","year":"2015","journal-title":"PLoS Neglected Trop Dis"},{"key":"10.1016\/j.micinf.2020.09.008_bib17","doi-asserted-by":"crossref","first-page":"4192","DOI":"10.1038\/s41598-018-22709-8","article-title":"An immunoproteomic approach revealing peptides from Sporothrix brasiliensis that induce a cellular immune response in subcutaneous sporotrichosis","volume":"8","author":"Almeida","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.micinf.2020.09.008_bib18","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00514-17","article-title":"Proteins potentially involved in immune evasion strategies in Sporothrix brasiliensis elucidated by ultra-high-resolution mass spectrometry","volume":"3","author":"Rossato","year":"2018","journal-title":"mSphere"},{"key":"10.1016\/j.micinf.2020.09.008_bib19","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.3389\/fmicb.2018.02286","article-title":"Extracellular vesicles from Sporothrix brasiliensis are an important virulence factor that induce an increase in fungal burden in experimental sporotrichosis","volume":"9","author":"Ikeda","year":"2018","journal-title":"Front Microbiol"},{"key":"10.1016\/j.micinf.2020.09.008_bib20","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1128\/JCM.00808-07","article-title":"Sporothrix brasiliensis, S. globosa, and S.\u00a0mexicana, three new Sporothrix species of clinical interest","volume":"45","author":"Marimon","year":"2007","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.micinf.2020.09.008_bib21","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1128\/JCM.00450-12","article-title":"Rapid identification of Sporothrix species by T3B fingerprinting","volume":"50","author":"Oliveira","year":"2012","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.micinf.2020.09.008_bib22","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s11046-011-9437-3","article-title":"Phenotypic and molecular identification of Sporothrix isolates from an epidemic area of sporotrichosis in Brazil","volume":"172","author":"Oliveira","year":"2011","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micinf.2020.09.008_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004282","article-title":"Characterization of the Paracoccidioides hypoxia response reveals new insights into pathogenesis mechanisms of this important human pathogenic fungus","volume":"9","author":"Lima","year":"2015","journal-title":"PLoS Neglected Trop Dis"},{"key":"10.1016\/j.micinf.2020.09.008_bib24","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/1472-6750-12-82","article-title":"NanoUPLC-MSE proteomic data assessment of soybean seeds using the Uniprot database","volume":"12","author":"Murad","year":"2012","journal-title":"BMC Biotechnol"},{"key":"10.1016\/j.micinf.2020.09.008_bib25","first-page":"2618","article-title":"Detection and expression analysis of recombinant proteins in plant-derived complex mixtures using nanoUPLC-MSE","volume":"34","author":"Murad","year":"2011","journal-title":"J\u00a0Separ Sci"},{"key":"10.1016\/j.micinf.2020.09.008_bib26","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1002\/pmic.200800564","article-title":"Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures","volume":"9","author":"Li","year":"2009","journal-title":"Proteomics"},{"key":"10.1016\/j.micinf.2020.09.008_bib27","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1002\/pmic.200800562","article-title":"The detection, correlation, and comparison of peptide precursor and product ions from data independent LC-MS with data dependant LC-MS\/MS","volume":"9","author":"Geromanos","year":"2009","journal-title":"Proteomics"},{"key":"10.1016\/j.micinf.2020.09.008_bib28","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1186\/1471-2164-15-943","article-title":"Comparative genomics of the major fungal agents of human and animal Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis","volume":"15","author":"Teixeira","year":"2014","journal-title":"BMC Genom"},{"key":"10.1016\/j.micinf.2020.09.008_bib29","series-title":"A\u00a0language and environment for statistical computing","author":"Team","year":"2017"},{"key":"10.1016\/j.micinf.2020.09.008_bib30","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.fbr.2016.09.001","article-title":"Melanin biosynthesis in pathogenic species of Sporothrix","volume":"31","author":"Almeida-Paes","year":"2017","journal-title":"Fungal Bio Rev"},{"key":"10.1016\/j.micinf.2020.09.008_bib31","doi-asserted-by":"crossref","first-page":"132635","DOI":"10.1155\/2015\/132635","article-title":"Role of heat-shock proteins in cellular function and in the biology of fungi","volume":"2015","author":"Tiwari","year":"2015","journal-title":"Biotechnol Res Int"},{"key":"10.1016\/j.micinf.2020.09.008_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006169","article-title":"Cell walls of the dimorphic fungal pathogens Sporothrix schenckii and Sporothrix brasiliensis exhibit bilaminate structures and sloughing of extensive and intact layers","volume":"12","author":"Lopes-Bezerra","year":"2018","journal-title":"PLoS Neglected Trop Dis"},{"key":"10.1016\/j.micinf.2020.09.008_bib33","doi-asserted-by":"crossref","first-page":"843","DOI":"10.3389\/fmicb.2017.00843","article-title":"Sporothrix schenckii sensu stricto and Sporothrix brasiliensis are differentially recognized by human peripheral blood mononuclear cells","volume":"8","author":"Martinez-Alvarez","year":"2017","journal-title":"Front Microbiol"},{"key":"10.1016\/j.micinf.2020.09.008_bib34","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1099\/00221287-144-3-671","article-title":"Role of trehalose in survival of Saccharomyces cerevisiae under osmotic stress","volume":"144","author":"Hounsa","year":"1998","journal-title":"Microbiology"},{"key":"10.1016\/j.micinf.2020.09.008_bib35","doi-asserted-by":"crossref","first-page":"212308","DOI":"10.1155\/2015\/212308","article-title":"Phenotypic characteristics associated with virulence of clinical isolates from the Sporothrix complex","volume":"2015","author":"Almeida-Paes","year":"2015","journal-title":"BioMed Res Int"},{"key":"10.1016\/j.micinf.2020.09.008_bib36","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.riam.2017.05.003","article-title":"Proteases of Sporothrix schenckii: cytopathological effects on a host-cell model","volume":"35","author":"Sabanero Lopez","year":"2018","journal-title":"Rev Iberoam De Micol"},{"key":"10.1016\/j.micinf.2020.09.008_bib37","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1128\/IAI.74.1.504-515.2006","article-title":"Urease produced by Coccidioides posadasii contributes to the virulence of this respiratory pathogen","volume":"74","author":"Mirbod-Donovan","year":"2006","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2020.09.008_bib38","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/S0002-9440(10)63734-0","article-title":"Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion","volume":"164","author":"Olszewski","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.micinf.2020.09.008_bib39","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1128\/IAI.68.2.443-448.2000","article-title":"Urease as a virulence factor in experimental cryptococcosis","volume":"68","author":"Cox","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.micinf.2020.09.008_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004790","article-title":"Intracellular growth is dependent on tyrosine catabolism in the dimorphic fungal pathogen Penicillium marneffei","volume":"11","author":"Boyce","year":"2015","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.micinf.2020.09.008_bib41","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1534\/g3.113.006809","article-title":"Cell-type-specific transcriptional profiles of the dimorphic pathogen Penicillium marneffei reflect distinct reproductive, morphological, and environmental demands","volume":"3","author":"Pasricha","year":"2013","journal-title":"G3 (Bethesda)"},{"key":"10.1016\/j.micinf.2020.09.008_bib42","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/10409230490440541","article-title":"FeII\/alpha-ketoglutarate-dependent hydroxylases and related enzymes","volume":"39","author":"Hausinger","year":"2004","journal-title":"Crit Rev Biochem Mol Biol"},{"key":"10.1016\/j.micinf.2020.09.008_bib43","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1128\/EC.4.12.2115-2128.2005","article-title":"Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing mycelium-to-yeast transition","volume":"4","author":"Nunes","year":"2005","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.micinf.2020.09.008_bib44","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1128\/AEM.02077-08","article-title":"Production of pyomelanin, a second type of melanin, via the tyrosine degradation pathway in Aspergillus fumigatus","volume":"75","author":"Schmaler-Ripcke","year":"2009","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.micinf.2020.09.008_bib45","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1093\/mmy\/myx068","article-title":"L-tyrosine induces the production of a pyomelanin-like pigment by the parasitic yeast-form of Histoplasma capsulatum","volume":"56","author":"Almeida-Paes","year":"2018","journal-title":"Med Mycol"},{"key":"10.1016\/j.micinf.2020.09.008_bib46","doi-asserted-by":"crossref","first-page":"8623","DOI":"10.1128\/AEM.02414-12","article-title":"Biosynthesis and functions of a melanoid pigment produced by species of the Sporothrix complex in the presence of L-tyrosine","volume":"78","author":"Almeida-Paes","year":"2012","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.micinf.2020.09.008_bib47","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0152796","article-title":"Melanins protect Sporothrix brasiliensis and Sporothrix schenckii from the antifungal effects of terbinafine","volume":"11","author":"Almeida-Paes","year":"2016","journal-title":"PloS One"},{"key":"10.1016\/j.micinf.2020.09.008_bib48","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.1099\/mic.0.081794-0","article-title":"Sporothrix schenckii complex biology: environment and fungal pathogenicity","volume":"160","author":"Tellez","year":"2014","journal-title":"Microbiology"},{"key":"10.1016\/j.micinf.2020.09.008_bib49","doi-asserted-by":"crossref","first-page":"835","DOI":"10.3109\/13693786.2013.807445","article-title":"Antioxidative and immunogenic properties of catalase-peroxidase protein in Penicillium marneffei","volume":"51","author":"Pongpom","year":"2013","journal-title":"Med Mycol"},{"key":"10.1016\/j.micinf.2020.09.008_bib50","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/1471-2180-11-162","article-title":"Calcium\/calmodulin kinase1 and its relation to thermotolerance and HSP90 in Sporothrix schenckii: an RNAi and yeast two-hybrid study","volume":"11","author":"Rodriguez-Caban","year":"2011","journal-title":"BMC Microbiol"}],"container-title":["Microbes and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457920301611?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1286457920301611?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T14:38:56Z","timestamp":1761143936000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1286457920301611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S1286457920301611"],"URL":"https:\/\/doi.org\/10.1016\/j.micinf.2020.09.008","relation":{},"ISSN":["1286-4579"],"issn-type":[{"value":"1286-4579","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative proteomics in the three major human pathogenic species of the genus Sporothrix","name":"articletitle","label":"Article Title"},{"value":"Microbes and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micinf.2020.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Institut Pasteur. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"104762"}}