{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:39:41Z","timestamp":1778873981671,"version":"3.51.4"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.micpath.2008.11.001","type":"journal-article","created":{"date-parts":[[2008,11,18]],"date-time":"2008-11-18T12:06:18Z","timestamp":1227009978000},"page":"114-118","source":"Crossref","is-referenced-by-count":18,"title":["Differential expression from two iron-responsive promoters in Salmonella enterica serovar Typhimurium reveals the presence of iron in macrophage-phagosomes"],"prefix":"10.1016","volume":"46","author":[{"given":"Clare M.","family":"Taylor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deenah","family":"Osman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer S.","family":"Cavet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2008.11.001_bib1","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1038\/nrmicro1046","article-title":"Iron and microbial infection","volume":"2","author":"Schaible","year":"2004","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.micpath.2008.11.001_bib2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1097\/00062752-199502010-00008","article-title":"The respiratory burst oxidase","volume":"2","author":"Babior","year":"1995","journal-title":"Curr Opin Hematol"},{"key":"10.1016\/j.micpath.2008.11.001_bib3","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S1074-7613(00)80004-7","article-title":"Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase","volume":"10","author":"Shiloh","year":"1999","journal-title":"Immunity"},{"key":"10.1016\/j.micpath.2008.11.001_bib4","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1046\/j.1365-2567.1999.00672.x","article-title":"High level expression of Nramp1G169 in RAW264.7 cell transfectants: analysis of intracellular iron transport","volume":"96","author":"Atkinson","year":"1999","journal-title":"Immunology"},{"key":"10.1016\/j.micpath.2008.11.001_bib5","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1042\/0264-6021:3540511","article-title":"Natural-resistance-associated macrophage protein 1 is an H+\/bivalent cation antiporter","volume":"354","author":"Goswami","year":"2001","journal-title":"Biochem J"},{"key":"10.1016\/j.micpath.2008.11.001_bib6","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s000110050330","article-title":"Macrophage NRAMP1 and its role in resistance to microbial infections","volume":"47","author":"Govoni","year":"1998","journal-title":"Inflamm Res"},{"key":"10.1016\/j.micpath.2008.11.001_bib7","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1084\/jem.192.9.1237","article-title":"Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane","volume":"192","author":"Jabado","year":"2000","journal-title":"J Exp Med"},{"key":"10.1016\/j.micpath.2008.11.001_bib8","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/jlb.58.4.382","article-title":"Natural resistance to infection with intracellular parasites: molecular genetics identifies Nramp1 as the Bcg\/Ity\/Lsh locus","volume":"58","author":"Vidal","year":"1995","journal-title":"J\u00a0Leukoc Biol"},{"key":"10.1016\/j.micpath.2008.11.001_bib9","doi-asserted-by":"crossref","first-page":"15705","DOI":"10.1073\/pnas.252415599","article-title":"Host-pathogen interactions: host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes","volume":"99","author":"Zaharik","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.micpath.2008.11.001_bib10","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1128\/IAI.67.3.1386-1392.1999","article-title":"Role of iron in Nramp1-mediated inhibition of mycobacterial growth","volume":"67","author":"Zwilling","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.micpath.2008.11.001_bib11","doi-asserted-by":"crossref","first-page":"5189","DOI":"10.1073\/pnas.83.14.5189","article-title":"Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent","volume":"83","author":"Fields","year":"1986","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.micpath.2008.11.001_bib12","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0378-1119(96)00560-4","article-title":"Identification of a new iron regulated locus of Salmonella typhi","volume":"183","author":"B\u00e4umler","year":"1996","journal-title":"Gene"},{"key":"10.1016\/j.micpath.2008.11.001_bib13","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1023\/B:BIOM.0000029432.69418.6a","article-title":"The structure of salmochelins: C-glucosylated enterobactins of Salmonella enterica","volume":"17","author":"Bister","year":"2004","journal-title":"Biometals"},{"key":"10.1016\/j.micpath.2008.11.001_bib14","doi-asserted-by":"crossref","first-page":"3677","DOI":"10.1073\/pnas.0737682100","article-title":"Salmochelins, siderophores of Salmonella enterica and uropathogenic Escherichia coli strains, are recognized by the outer membrane receptor IroN","volume":"100","author":"Hantke","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.micpath.2008.11.001_bib15","doi-asserted-by":"crossref","first-page":"11075","DOI":"10.1021\/ja0522027","article-title":"In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes","volume":"127","author":"Lin","year":"2005","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.micpath.2008.11.001_bib16","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1128\/JB.00926-07","article-title":"Fur regulates expression of the Salmonella pathogenicity island 1 type III secretion system through HilD","volume":"190","author":"Ellermeier","year":"2008","journal-title":"J Bacteriol"},{"key":"10.1016\/j.micpath.2008.11.001_bib17","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0378-1119(87)90095-3","article-title":"Improved single and multicopy lac-based cloning vector for protein and operon fusions","volume":"53","author":"Simons","year":"1987","journal-title":"Gene"},{"key":"10.1016\/j.micpath.2008.11.001_bib18","doi-asserted-by":"crossref","first-page":"29478","DOI":"10.1074\/jbc.M303381200","article-title":"Global iron-dependent gene regulation in Escherichia coli","volume":"278","author":"McHugh","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.micpath.2008.11.001_bib19","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1128\/MMBR.51.4.509-518.1987","article-title":"Molecular mechanism of regulation of siderophore-mediated iron assimilation","volume":"51","author":"Bagg","year":"1987","journal-title":"Microbiol Rev"},{"key":"10.1016\/j.micpath.2008.11.001_bib20","doi-asserted-by":"crossref","first-page":"5471","DOI":"10.1021\/bi00391a039","article-title":"Ferric uptake regulation protein acts as a repressor, employing iron(II) as a cofactor to bind the operator of an iron transport operon in Escherichia coli","volume":"26","author":"Bagg","year":"1987","journal-title":"Biochemistry"},{"key":"10.1016\/j.micpath.2008.11.001_bib21","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1128\/JB.187.3.912-922.2005","article-title":"Transcriptional regulation of sitABCD of Salmonella enterica serovar Typhimurium by MntR and Fur","volume":"187","author":"Ikeda","year":"2005","journal-title":"J Bacteriol"},{"key":"10.1016\/j.micpath.2008.11.001_bib22","doi-asserted-by":"crossref","first-page":"2855","DOI":"10.1242\/jcs.111.19.2855","article-title":"Localisation of Nramp1 in macrophages: modulation with activation and infection","volume":"111","author":"Searle","year":"1998","journal-title":"J Cell Sci"},{"key":"10.1016\/j.micpath.2008.11.001_bib23","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1042\/BJ20040808","article-title":"Incomplete glycosylation and defective intracellular targeting of mutant solute carrier family 11 member 1 (Slc11a1)","volume":"382","author":"White","year":"2002","journal-title":"Biochem J"},{"key":"10.1016\/j.micpath.2008.11.001_bib24","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1074\/jbc.M105508200","article-title":"Nramp1 modifies the fusion of Salmonella typhimurium containing vacuoles with cellular endomembranes in macrophages","volume":"277","author":"Cuellar-Mata","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.micpath.2008.11.001_bib25","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1365-2958.1997.3271699.x","article-title":"Functional analysis of ssaJ and the ssaK\/U operon, 13 genes encoding components of the type III secretion apparatus of Salmonella Pathogenicity Island 2","volume":"24","author":"Hensel","year":"1997","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micpath.2008.11.001_bib26","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1182\/blood-2003-02-0425","article-title":"Iron, manganese and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane","volume":"102","author":"Forbes","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.micpath.2008.11.001_bib27","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1046\/j.1365-2958.2003.03313.x","article-title":"Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica","volume":"47","author":"Eriksson","year":"2003","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micpath.2008.11.001_bib28","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1128\/IAI.50.2.392-397.1985","article-title":"The ability of Salmonella typhimurium to produce the siderophore enterobactin is not a virulence factor in mouse typhoid","volume":"50","author":"Benjamin","year":"1985","journal-title":"Infect Immun"},{"key":"10.1016\/j.micpath.2008.11.001_bib29","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.1111\/j.1365-2958.1992.tb02197.x","article-title":"Characterization of the micro-environment of Salmonella typhimurium-containing vacuoles within MDCK epithelial cells","volume":"6","author":"Garcia-del Portillo","year":"1992","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micpath.2008.11.001_bib30","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1111\/j.1462-5822.2007.01099.x","article-title":"During infection of epithelial cells Salmonella enterica serovar Typhimurium undergoes a time-dependent transcriptional adaptation that results in simultaneous expression of three type 3 secretion systems","volume":"10","author":"Hautefort","year":"2008","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.micpath.2008.11.001_bib31","doi-asserted-by":"crossref","first-page":"38441","DOI":"10.1074\/jbc.M207677200","article-title":"A nickel-cobalt-sensing ArsR-SmtB family repressor. Contributions of cytosol and effector binding sites to metal selectivity","volume":"277","author":"Cavet","year":"2002","journal-title":"J Biol Chem"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401008001447?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401008001447?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T10:23:55Z","timestamp":1632219835000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401008001447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S0882401008001447"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2008.11.001","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}