{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T19:54:58Z","timestamp":1778615698744,"version":"3.51.4"},"reference-count":17,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.micpath.2013.12.002","type":"journal-article","created":{"date-parts":[[2013,12,17]],"date-time":"2013-12-17T08:45:26Z","timestamp":1387269926000},"page":"36-39","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["Inhibition of the sodium-translocating NADH-ubiquinone oxidoreductase [Na+-NQR] decreases cholera toxin production in Vibrio cholerae O1 at the late exponential growth phase"],"prefix":"10.1016","volume":"66","author":[{"given":"Yusuke","family":"Minato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara R.","family":"Fassio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rylan L.","family":"Reddekopp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia C.","family":"H\u00e4se","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2013.12.002_bib1","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1073\/pnas.84.9.2833","article-title":"Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin","volume":"84","author":"Taylor","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.micpath.2013.12.002_bib2","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1016\/j.biocel.2007.07.005","article-title":"Vibrio cholerae: cholera toxin","volume":"39","author":"Vanden Broeck","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.micpath.2013.12.002_bib3","doi-asserted-by":"crossref","first-page":"5403","DOI":"10.1073\/pnas.88.12.5403","article-title":"Regulatory cascade controls virulence in Vibrio cholerae","volume":"88","author":"DiRita","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.micpath.2013.12.002_bib4","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1128\/MMBR.65.3.353-370.2001","article-title":"Sodium ion cycle in bacterial pathogens: evidence from cross-genome comparisons","volume":"65","author":"H\u00e4se","year":"2001","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1016\/j.micpath.2013.12.002_bib5","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s00203-007-0254-5","article-title":"Regulation of expression of Na+-translocating NADH: quinone oxidoreductase genes in Vibrio harveyi and Klebsiella pneumoniae","volume":"188","author":"Fadeeva","year":"2007","journal-title":"Arch Microbiol"},{"key":"10.1016\/j.micpath.2013.12.002_bib6","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1471-2164-12-51","article-title":"Deep sequencing-based analysis of the anaerobic stimulon in Neisseria gonorrhoeae","volume":"12","author":"Isabella","year":"2011","journal-title":"BMC Genomics"},{"key":"10.1016\/j.micpath.2013.12.002_bib7","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1046\/j.1365-2958.2002.02857.x","article-title":"Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae","volume":"43","author":"Merrell","year":"2002","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micpath.2013.12.002_bib8","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1128\/JCM.25.12.2314-2316.1987","article-title":"Large production of cholera toxin by Vibrio cholerae O1 in yeast extract peptone water","volume":"25","author":"Iwanaga","year":"1987","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.micpath.2013.12.002_bib9","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/0076-6879(94)35167-8","article-title":"Regulation of cholera toxin by temperature, pH, and osmolarity","volume":"235","author":"Gardel","year":"1994","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.micpath.2013.12.002_bib10","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1073\/pnas.96.6.3183","article-title":"Effects of changes in membrane sodium flux on virulence gene expression in Vibrio cholerae","volume":"96","author":"H\u00e4se","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.micpath.2013.12.002_bib11","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1111\/j.1365-2958.1995.mmi_17061133.x","article-title":"Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance","volume":"17","author":"Chiang","year":"1995","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.micpath.2013.12.002_bib12","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1146\/annurev.bi.54.070185.005055","article-title":"The mitochondrial electron transport and oxidative phosphorylation system","volume":"54","author":"Hatefi","year":"1985","journal-title":"Annu Rev Biochem"},{"key":"10.1016\/j.micpath.2013.12.002_bib13","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1128\/jb.176.8.2143-2150.1994","article-title":"Mutations in NADH: ubiquinone oxidoreductase of Escherichia coli affect growth on mixed amino acids","volume":"176","author":"Pr\u00fcss","year":"1994","journal-title":"J\u00a0Bacteriol"},{"key":"10.1016\/j.micpath.2013.12.002_bib14","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1099\/mic.0.064865-0","article-title":"Central metabolism controls transcription of a virulence gene regulator in Vibrio cholerae","volume":"159","author":"Minato","year":"2013","journal-title":"Microbiology"},{"key":"10.1016\/j.micpath.2013.12.002_bib15","doi-asserted-by":"crossref","first-page":"3163","DOI":"10.1128\/IAI.00071-13","article-title":"Na+\/H+ antiport is essential for Yersinia pestis virulence","volume":"81","author":"Minato","year":"2013","journal-title":"Infect Immun"},{"key":"10.1016\/j.micpath.2013.12.002_bib16","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1128\/MMBR.69.1.12-50.2005","article-title":"The acetate switch","volume":"69","author":"Wolfe","year":"2005","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1016\/j.micpath.2013.12.002_bib17","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nrd3013","article-title":"Anti-virulence strategies to combat bacteria-mediated disease","volume":"9","author":"Rasko","year":"2010","journal-title":"Nat Rev Drug Discov"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401013001514?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401013001514?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T06:48:06Z","timestamp":1597214886000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401013001514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":17,"alternative-id":["S0882401013001514"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2013.12.002","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of the sodium-translocating NADH-ubiquinone oxidoreductase [Na+-NQR] decreases cholera toxin production in Vibrio cholerae O1 at the late exponential growth phase","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2013.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}