{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T19:46:39Z","timestamp":1766087199423,"version":"build-2065373602"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"am","delay-in-days":304,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000774","name":"Defense Threat Reduction Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.micpath.2017.03.015","type":"journal-article","created":{"date-parts":[[2017,3,18]],"date-time":"2017-03-18T16:00:20Z","timestamp":1489852820000},"page":"175-180","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["A proteasome inhibitor produced by Burkholderia pseudomallei modulates intracellular growth"],"prefix":"10.1016","volume":"107","author":[{"given":"Sariqa","family":"Wagley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muthita","family":"Vanaporn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darawan","family":"Rinchai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Conejero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganjana","family":"Lertmemongkolchai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory J.","family":"Bancroft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard W.","family":"Titball","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2017.03.015_bib1","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1094\/MPMI.2004.17.1.90","article-title":"Functional analysis of genes involved in the synthesis of syringolin A by Pseudomonas syringae pv. syringae B301 D-R","volume":"17","author":"Amrein","year":"2004","journal-title":"Mol. Plant Microbe. Interact."},{"key":"10.1016\/j.micpath.2017.03.015_bib2","doi-asserted-by":"crossref","first-page":"13192","DOI":"10.1021\/ja3052156","article-title":"Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens","volume":"134","author":"Biggins","year":"2012","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.micpath.2017.03.015_bib3","doi-asserted-by":"crossref","first-page":"9484","DOI":"10.1021\/ja504617n","article-title":"The chemical arsenal of Burkholderia pseudomallei is essential for pathogenicity","volume":"136","author":"Biggins","year":"2014","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.micpath.2017.03.015_bib4","first-page":"11","volume":"10","author":"Blankenberg","year":"2010","journal-title":"Curr. Protoc. Mol. Biol."},{"key":"10.1016\/j.micpath.2017.03.015_bib5","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.1021\/jm700948z","article-title":"Genome mining for novel natural product discovery","volume":"51","author":"Challis","year":"2008","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.micpath.2017.03.015_bib6","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1128\/IAI.00503-08","article-title":"Human polymorphonuclear neutrophil responses to Burkholderia pseudomallei in healthy and diabetic subjects","volume":"77","author":"Chanchamroen","year":"2009","journal-title":"Infect Immun."},{"key":"10.1016\/j.micpath.2017.03.015_bib7","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.ajpath.2011.03.031","article-title":"Low-dose exposure of C57BL\/6 mice to Burkholderia pseudomallei mimics chronic human melioidosis","volume":"179","author":"Conejero","year":"2011","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.micpath.2017.03.015_bib8","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/j.biochi.2010.06.023","article-title":"Proteasome inhibitors: dozens of molecules and still counting","volume":"92","author":"de Bettignies","year":"2010","journal-title":"Biochimie"},{"key":"10.1016\/j.micpath.2017.03.015_bib9","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1021\/mp700137g","article-title":"Nonribosomal peptide synthetases involved in the production of medically relevant natural products","volume":"5","author":"Felnagle","year":"2008","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.micpath.2017.03.015_bib10","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1101\/gr.4086505","article-title":"Galaxy: a platform for interactive large-scale genome analysis","volume":"15","author":"Giardine","year":"2005","journal-title":"Genome Res."},{"key":"10.1016\/j.micpath.2017.03.015_bib11","doi-asserted-by":"crossref","first-page":"R86","DOI":"10.1186\/gb-2010-11-8-r86","article-title":"Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences","volume":"11","author":"Goecks","year":"2010","journal-title":"Genome Biol."},{"key":"10.1016\/j.micpath.2017.03.015_bib12","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/nature06782","article-title":"A\u00a0plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism","volume":"452","author":"Groll","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.micpath.2017.03.015_bib13","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1128\/MMBR.00012-07","article-title":"Siderophore-based iron acquisition and pathogen control","volume":"71","author":"Miethke","year":"2007","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.micpath.2017.03.015_bib14","doi-asserted-by":"crossref","first-page":"e00926","DOI":"10.1128\/mBio.00926-13","article-title":"Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development","volume":"5","author":"Moule","year":"2014","journal-title":"MBio"},{"key":"10.1016\/j.micpath.2017.03.015_bib15","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3389\/fmicb.2011.00139","article-title":"Molecular investigations of PenA-mediated beta-lactam resistance in Burkholderia pseudomallei","volume":"2","author":"Rholl","year":"2011","journal-title":"Front Microbiol."},{"key":"10.1016\/j.micpath.2017.03.015_bib16","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1080\/15548627.2015.1040969","article-title":"Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils","volume":"11","author":"Rinchai","year":"2015","journal-title":"Autophagy"},{"key":"10.1016\/j.micpath.2017.03.015_bib17","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1111\/j.1462-2920.2007.01278.x","article-title":"Identification of genes involved in the biosynthesis of the cytotoxic compound glidobactin from a soil bacterium","volume":"9","author":"Schellenberg","year":"2007","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.micpath.2017.03.015_bib18","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1099\/mic.0.050823-0","article-title":"Superoxide dismutase C is required for intracellular survival and virulence of Burkholderia pseudomallei","volume":"157","author":"Vanaporn","year":"2011","journal-title":"Microbiology"},{"key":"10.1016\/j.micpath.2017.03.015_bib19","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1128\/JB.01046-13","article-title":"The twin arginine translocation system is essential for aerobic growth and full virulence of Burkholderia thailandensis","volume":"196","author":"Wagley","year":"2014","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.micpath.2017.03.015_bib21","doi-asserted-by":"crossref","first-page":"9259","DOI":"10.1073\/pnas.1401734111","article-title":"Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes","volume":"111","author":"Wang","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.micpath.2017.03.015_bib22","doi-asserted-by":"crossref","first-page":"14240","DOI":"10.1073\/pnas.0403302101","article-title":"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei","volume":"101","author":"Holden","year":"2004","journal-title":"Proc. Nat. Acad. Sci. U. S. A."},{"key":"10.1016\/j.micpath.2017.03.015_bib23","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1128\/jb.178.5.1310-1319.1996","article-title":"Flagellin A is essential for the virulence of Vibrio anguillarum","volume":"178","author":"Milton","year":"1996","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2017.03.015_bib24","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1038\/nbt1183-784","article-title":"A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria","volume":"1","author":"Simon","year":"1983","journal-title":"Nat. Biotech."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401016303436?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401016303436?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:19:00Z","timestamp":1760109540000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401016303436"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":23,"alternative-id":["S0882401016303436"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2017.03.015","relation":{},"ISSN":["0882-4010"],"issn-type":[{"type":"print","value":"0882-4010"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A proteasome inhibitor produced by Burkholderia pseudomallei modulates intracellular growth","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2017.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}