{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T05:14:15Z","timestamp":1782364455297,"version":"3.54.5"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["5\/7\/1259\/2015-RCH"],"award-info":[{"award-number":["5\/7\/1259\/2015-RCH"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.micpath.2017.08.046","type":"journal-article","created":{"date-parts":[[2017,9,2]],"date-time":"2017-09-02T02:46:17Z","timestamp":1504320377000},"page":"187-192","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Enhanced cytopathic effect of Japanese encephalitis virus strain SA14-14-2: Probable association of mutation in amino acid of its envelope protein"],"prefix":"10.1016","volume":"111","author":[{"given":"Barnali","family":"Nath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3769-1752","authenticated-orcid":false,"given":"Ashutosh","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siraj A.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2017.08.046_bib1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1093\/trstmh\/trv045","article-title":"Characterization of Japanese encephalitis virus (JEV) genotype III clinical isolates in northeast India","volume":"109","author":"Khan","year":"2015","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.micpath.2017.08.046_bib2","doi-asserted-by":"crossref","first-page":"766","DOI":"10.2471\/BLT.10.085233","article-title":"Estimated global incidence of Japanese encephalitis: a systematic review","volume":"89","author":"Campbell","year":"2011","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.micpath.2017.08.046_bib3","doi-asserted-by":"crossref","first-page":"930","DOI":"10.4269\/ajtmh.2010.09-0676","article-title":"Japanese encephalitis in travelers from non-endemic countries, 1973-2008","volume":"82","author":"Hills","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.micpath.2017.08.046_bib4","first-page":"243","article-title":"Japanese encephalitis and its epidemiology","volume":"3","author":"SSaHC","year":"2015","journal-title":"J.\u00a0Infect. Dis. Ther."},{"key":"10.1016\/j.micpath.2017.08.046_bib5","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jcv.2011.06.001","article-title":"A\u00a0comparison of clinical features of Japanese encephalitis virus infection in the adult and pediatric age group with Acute Encephalitis Syndrome","volume":"52","author":"Borah","year":"2011","journal-title":"J.\u00a0Clin. Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib6","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12865-017-0197-9","article-title":"Insight into SNPs and epitopes of E protein of newly emerged genotype-I isolates of JEV from Midnapur, West Bengal, India","volume":"18","author":"Banerjee","year":"2017","journal-title":"BMC Immunol."},{"key":"10.1016\/j.micpath.2017.08.046_bib7","series-title":"Assam hit by Acute JE Vaccine Crunch","author":"Bora","year":"2016"},{"key":"10.1016\/j.micpath.2017.08.046_bib8","series-title":"Flaviviridae: the Viruses and Their Replication","author":"Lindenbach","year":"2007"},{"key":"10.1016\/j.micpath.2017.08.046_bib9","doi-asserted-by":"crossref","first-page":"S98","DOI":"10.1038\/nm1144","article-title":"Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses","volume":"10","author":"Mackenzie","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.micpath.2017.08.046_bib10","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1146\/annurev.mi.44.100190.003245","article-title":"Flavivirus genome organization, expression, and replication","volume":"44","author":"Chambers","year":"1990","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.micpath.2017.08.046_bib11","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0042-6822(87)90144-9","article-title":"Complete nucleotide sequence of the Japanese encephalitis virus genome RNA","volume":"161","author":"Sumiyoshi","year":"1987","journal-title":"Virology"},{"key":"10.1016\/j.micpath.2017.08.046_bib12","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1128\/JVI.06072-11","article-title":"Crystal structure of the Japanese encephalitis virus envelope protein","volume":"86","author":"Luca","year":"2011","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib13","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.virol.2008.06.017","article-title":"Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein","volume":"379","author":"Chien","year":"2008","journal-title":"Virology"},{"key":"10.1016\/j.micpath.2017.08.046_bib14","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1006\/viro.2001.0986","article-title":"Highly sulfated forms of heparan sulfate are involved in Japanese encephalitis virus infection","volume":"286","author":"Su","year":"2001","journal-title":"Virology"},{"key":"10.1016\/j.micpath.2017.08.046_bib15","series-title":"Virology","article-title":"Flaviviruses","author":"Monath","year":"1990"},{"key":"10.1016\/j.micpath.2017.08.046_bib16","series-title":"The Togaviridae and Flaviviridae","article-title":"Structure of the flavivirus genome","author":"Rice","year":"1986"},{"key":"10.1016\/j.micpath.2017.08.046_bib17","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1128\/JVI.76.4.1932-1943.2002","article-title":"Single mutation in the flavivirus envelope protein hinge region increases neurovirulence for mice and monkeys but decreases viscerotropism for monkeys: relevance to development and safety testing of live, attenuated vaccines","volume":"76","author":"Monath","year":"2002","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib18","doi-asserted-by":"crossref","first-page":"8142","DOI":"10.1128\/JVI.70.11.8142-8147.1996","article-title":"Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virus","volume":"70","author":"Stiasny","year":"1996","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib19","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1128\/JVI.77.5.3091-3098.2003","article-title":"Origin and evolution of Japanese encephalitis virus in southeast Asia","volume":"77","author":"Solomon","year":"2003","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib20","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1016\/j.vaccine.2010.02.105","article-title":"Phenotypic and genotypic characteristics of Japanese encephalitis attenuated live vaccine virus SA14-14-2 and their stabilities","volume":"28","author":"Yu","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.micpath.2017.08.046_bib21","first-page":"493","article-title":"A\u00a0simple method of estimation of 50% end points","volume":"27","author":"Reed","year":"1938","journal-title":"Am. J. Hyg."},{"key":"10.1016\/j.micpath.2017.08.046_bib22","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/nprot.2010.5","article-title":"A\u00a0unified platform for automated protein structure and function prediction","volume":"5","author":"Roy","year":"2010","journal-title":"Nat. Protoc."},{"issue":"Suppl.\u00a08","key":"10.1016\/j.micpath.2017.08.046_bib23","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/prot.21702","article-title":"Template-based modeling and free modeling by I-TASSER in CASP7","volume":"69","author":"Zhang","year":"2007","journal-title":"Proteins"},{"key":"10.1016\/j.micpath.2017.08.046_bib24","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0959-440X(02)00283-X","article-title":"Unraveling hot spots in binding interfaces: progress and challenges","volume":"12","author":"DeLano","year":"2002","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.micpath.2017.08.046_bib25","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1002\/jcc.21256","article-title":"AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility","volume":"30","author":"Morris","year":"2009","journal-title":"J.\u00a0Comput. Chem."},{"key":"10.1016\/j.micpath.2017.08.046_bib26","first-page":"57","article-title":"Python: a programming language for software integration and development","volume":"17","author":"Sanner","year":"1999","journal-title":"J.\u00a0Mol. Graph Model"},{"key":"10.1016\/j.micpath.2017.08.046_bib27","first-page":"396","article-title":"Binding-sites prediction assisting protein-protein docking","volume":"58","author":"Konc","year":"2011","journal-title":"Acta Chim. Slov."},{"key":"10.1016\/j.micpath.2017.08.046_bib28","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","article-title":"AutoDock Vina: improving the speed and accuracy of\u00a0docking with a new scoring function, efficient optimization, and multithreading","volume":"31","author":"Trott","year":"2009","journal-title":"J.\u00a0Comput. Chem."},{"key":"10.1016\/j.micpath.2017.08.046_bib29","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s11626-014-9859-6","article-title":"Molecular characterization of E2 glycoprotein of classical swine fever virus: adaptation and propagation in porcine kidney cells","volume":"51","author":"Kumar","year":"2015","journal-title":"In\u00a0Vitro Cell Dev. Biol. Anim."},{"key":"10.1016\/j.micpath.2017.08.046_bib30","doi-asserted-by":"crossref","first-page":"5627","DOI":"10.1128\/JVI.75.12.5627-5637.2001","article-title":"Adaptation of tick-borne encephalitis virus to BHK-21 cells results in the formation of multiple heparan sulfate binding sites in the envelope protein and attenuation in\u00a0vivo","volume":"75","author":"Mandl","year":"2001","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib31","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0378-1135(92)90151-I","article-title":"Recombinant polypeptide from the gp48 region of the bovine viral diarrhea virus (BVDV) detects serum antibodies in vaccinated and infected cattle","volume":"32","author":"Kwang","year":"1992","journal-title":"Vet. Microbiol."},{"issue":"Pt 3","key":"10.1016\/j.micpath.2017.08.046_bib32","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1099\/0022-1317-71-3-531","article-title":"Immunoaffinity purification and characterization of the envelope protein E1 of hog cholera virus","volume":"71","author":"Wensvoort","year":"1990","journal-title":"J.\u00a0Gen. Virol."},{"issue":"Pt 11","key":"10.1016\/j.micpath.2017.08.046_bib33","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1099\/0022-1317-78-11-2711","article-title":"The molecular basis of virulence of the encephalitogenic flaviviruses","volume":"78","author":"McMinn","year":"1997","journal-title":"J.\u00a0Gen. Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib34","doi-asserted-by":"crossref","first-page":"9192","DOI":"10.1021\/ja202219n","article-title":"Signature of mobile hydrogen bonding of lysine side chains from long-range 15N-13C scalar J-couplings and computation","volume":"133","author":"Zandarashvili","year":"2011","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.micpath.2017.08.046_bib35","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1128\/JVI.75.2.934-942.2001","article-title":"Molecular basis for attenuation of neurovirulence of a yellow fever Virus\/Japanese encephalitis virus chimera vaccine (ChimeriVax-JE)","volume":"75","author":"Arroyo","year":"2001","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib36","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/0042-6822(92)90177-Q","article-title":"Mutations in the envelope protein of Japanese encephalitis virus affect entry into cultured cells and virulence in mice","volume":"191","author":"Hasegawa","year":"1992","journal-title":"Virology"},{"key":"10.1016\/j.micpath.2017.08.046_bib37","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.str.2009.02.010","article-title":"Binding of small-molecule ligands to proteins: \u201cwhat you see\u201d is not always \u201cwhat you get\u201d","volume":"17","author":"Mobley","year":"2009","journal-title":"Structure"},{"key":"10.1016\/j.micpath.2017.08.046_bib38","doi-asserted-by":"crossref","DOI":"10.1093\/ve\/vew009","article-title":"Inference of Japanese encephalitis virus ecological and evolutionary dynamics from passive and active virus surveillance","volume":"2","author":"Pham","year":"2016","journal-title":"Virus Evol."},{"key":"10.1016\/j.micpath.2017.08.046_bib39","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.jtbi.2005.09.024","article-title":"Information catastrophe in RNA viruses through replication thresholds","volume":"240","author":"Sole","year":"2006","journal-title":"J.\u00a0Theor. Biol."},{"key":"10.1016\/j.micpath.2017.08.046_bib40","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.1099\/vir.0.80500-0","article-title":"Hepatitis C virus population analysis of a single-source nosocomial outbreak reveals an inverse correlation between viral load and quasispecies complexity","volume":"85","author":"Mas","year":"2004","journal-title":"J.\u00a0Gen. Virol."},{"key":"10.1016\/j.micpath.2017.08.046_bib41","doi-asserted-by":"crossref","first-page":"6895","DOI":"10.1073\/pnas.111085598","article-title":"RNA virus error catastrophe: direct molecular test by using ribavirin","volume":"98","author":"Crotty","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.micpath.2017.08.046_bib42","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1073\/pnas.96.4.1492","article-title":"Lethal mutagenesis of HIV with mutagenic nucleoside analogs","volume":"96","author":"Loeb","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401017309464?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401017309464?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T17:30:19Z","timestamp":1719423019000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401017309464"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":42,"alternative-id":["S0882401017309464"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2017.08.046","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhanced cytopathic effect of Japanese encephalitis virus strain SA14-14-2: Probable association of mutation in amino acid of its envelope protein","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2017.08.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}