{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T03:19:53Z","timestamp":1789442393865,"version":"build-2803163510"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"JSPS","doi-asserted-by":"publisher","award":["JP16K11516"],"award-info":[{"award-number":["JP16K11516"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.micpath.2018.02.043","type":"journal-article","created":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T01:15:45Z","timestamp":1519348545000},"page":"191-199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Gastrointestinal colonisation and systemic spread of Candida albicans in mice treated with antibiotics and prednisolone"],"prefix":"10.1016","volume":"117","author":[{"given":"Michiyo","family":"Kobayashi-Sakamoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2782-2763","authenticated-orcid":false,"given":"Riyoko","family":"Tamai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiko","family":"Isogai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Kiyoura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2018.02.043_bib1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jdsr.2014.12.001","article-title":"Innate immunity to Candida albicans","volume":"51","author":"Kiyoura","year":"2015","journal-title":"Japanese Dental Sci. Rev."},{"key":"10.1016\/j.micpath.2018.02.043_bib2","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.micpath.2011.06.009","article-title":"Candida albicans enhances invasion of human gingival epithelial cells and gingival fibroblasts by Porphyromonas gingivalis","volume":"51","author":"Tamai","year":"2011","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2018.02.043_bib3","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1128\/IAI.06146-11","article-title":"Interplay between Candida albicans and the mammalian innate host defense","volume":"80","author":"Cheng","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.02.043_bib4","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s10156-004-0330-6","article-title":"Protective effects of human saliva on experimental murine oral candidiasis","volume":"10","author":"Kamagata-Kiyoura","year":"2004","journal-title":"J. Infect. Chemother."},{"key":"10.1016\/j.micpath.2018.02.043_bib5","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1086\/496922","article-title":"The epidemiology and attributable outcomes of candidemia in adults and children hospitalized in the United States: a propensity analysis","volume":"41","author":"Zaoutis","year":"2005","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.micpath.2018.02.043_bib6","doi-asserted-by":"crossref","first-page":"e156","DOI":"10.1097\/TXD.0000000000000673","article-title":"Invasive candida infections in liver transplant recipients: clinical features and risk factors for mortality","volume":"3","author":"Bassetti","year":"2017","journal-title":"Transplant. Direct."},{"key":"10.1016\/j.micpath.2018.02.043_bib7","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1128\/IAI.00449-12","article-title":"Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy","volume":"80","author":"Mason","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.02.043_bib8","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nri3684","article-title":"The mycobiota: interactions between commensal fungi and the host immune system","volume":"14","author":"Underhill","year":"2014","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.micpath.2018.02.043_bib9","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1097\/ACI.0b013e328358cc0b","article-title":"Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis","volume":"12","author":"Puel","year":"2012","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"key":"10.1016\/j.micpath.2018.02.043_bib10","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1126\/science.1200439","article-title":"Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity","volume":"332","author":"Puel","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.micpath.2018.02.043_bib11","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.chom.2012.04.008","article-title":"Th17 cells in immunity to Candida albicans","volume":"11","author":"Hernandez-Santos","year":"2012","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.micpath.2018.02.043_bib12","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/1471-2334-13-82","article-title":"Frequent detection of 'azole' resistant Candida species among late presenting AIDS patients in northwest Ethiopia","volume":"13","author":"Mulu","year":"2013","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.micpath.2018.02.043_bib13","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1111\/j.1365-2958.2004.04350.x","article-title":"Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p","volume":"54","author":"Bensen","year":"2004","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micpath.2018.02.043_bib14","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.tim.2014.07.001","article-title":"Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels","volume":"22","author":"Brown","year":"2014","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.micpath.2018.02.043_bib15","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1080\/21505594.2015.1012981","article-title":"Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface","volume":"6","author":"Moyes","year":"2015","journal-title":"Virulence"},{"key":"10.1016\/j.micpath.2018.02.043_bib16","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1111\/j.1567-1364.2009.00524.x","article-title":"Identifying infection-associated genes of Candida albicans in the postgenomic era","volume":"9","author":"Wilson","year":"2009","journal-title":"FEMS Yeast Res."},{"key":"10.1016\/j.micpath.2018.02.043_bib17","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/cmi.12388","article-title":"Candida albicans colonization and dissemination from the murine gastrointestinal tract: the influence of morphology and Th17 immunity","volume":"17","author":"Vautier","year":"2015","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.micpath.2018.02.043_bib18","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1348-0421.2003.tb03403.x","article-title":"A novel murine model of oral candidiasis with local symptoms characteristic of oral thrush","volume":"47","author":"Takakura","year":"2003","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.micpath.2018.02.043_bib19","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.micinf.2014.06.007","article-title":"Involvement of IL-17A in preventing the development of deep-seated candidiasis from oropharyngeal infection","volume":"16","author":"Mosci","year":"2014","journal-title":"Microbes Infect."},{"key":"10.1016\/j.micpath.2018.02.043_bib20","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1128\/EC.00196-13","article-title":"Murine models of Candida gastrointestinal colonization and dissemination","volume":"12","author":"Koh","year":"2013","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.micpath.2018.02.043_bib21","doi-asserted-by":"crossref","first-page":"E31","DOI":"10.3314\/mmj.56.E31","article-title":"A novel Murine Candidiasis model with severe colonization in the stomach induced by N-acetylglucosamine-treatment and its scoring system based on local characteristic stomach symptoms","volume":"56","author":"Ishijima","year":"2015","journal-title":"Med. Mycol. J."},{"key":"10.1016\/j.micpath.2018.02.043_bib22","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1084\/jem.20081463","article-title":"Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis","volume":"206","author":"Conti","year":"2009","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micpath.2018.02.043_bib23","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1038\/aps.2015.76","article-title":"Prednisone treatment inhibits the differentiation of B lymphocytes into plasma cells in MRL\/MpSlac-lpr mice","volume":"36","author":"Yan","year":"2015","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.micpath.2018.02.043_bib24","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1016\/S0140-6736(03)14904-5","article-title":"Glucocorticoids and invasive fungal infections","volume":"362","author":"Lionakis","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.micpath.2018.02.043_bib25","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.4049\/jimmunol.178.3.1845","article-title":"Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia","volume":"178","author":"de Kruif","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2018.02.043_bib26","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s10156-003-0285-Z","article-title":"Reduced activity of Candida detachment factors in the saliva of the elderly","volume":"10","author":"Kamagata-Kiyoura","year":"2004","journal-title":"J. Infect. Chemother."},{"key":"10.1016\/j.micpath.2018.02.043_bib27","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.micres.2013.02.008","article-title":"Disruption of the intestinal mucosal barrier in Candida albicans infections","volume":"168","author":"Yan","year":"2013","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.micpath.2018.02.043_bib28","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1371\/journal.ppat.0040035","article-title":"Mucosal damage and neutropenia are required for Candida albicans dissemination","volume":"4","author":"Koh","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.micpath.2018.02.043_bib29","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1128\/AAC.00530-06","article-title":"Development of an orogastrointestinal mucosal model of candidiasis with dissemination to visceral organs","volume":"50","author":"Clemons","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2018.02.043_bib30","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.4049\/jimmunol.161.7.3543","article-title":"IFN-gamma is required for IL-12 responsiveness in mice with Candida albicans infection","volume":"161","author":"Cenci","year":"1998","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2018.02.043_bib31","doi-asserted-by":"crossref","first-page":"686597","DOI":"10.1155\/2011\/686597","article-title":"IL-12 and related cytokines: function and regulatory implications in Candida albicans infection","volume":"2011","author":"Ashman","year":"2011","journal-title":"Clin. Dev. Immunol."},{"key":"10.1016\/j.micpath.2018.02.043_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2011.02262.x","article-title":"The contribution of mouse models to our understanding of systemic candidiasis","volume":"320","author":"Szabo","year":"2011","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.micpath.2018.02.043_bib33","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/0006-2952(77)90087-9","article-title":"Effect of prednisolone on the activities of the intracellular enzymes of collagen biosynthesis in rat liver and skin","volume":"26","author":"Risteli","year":"1977","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.micpath.2018.02.043_bib34","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1046\/j.1365-2273.2003.00656.x","article-title":"Influence of prednisolone on the secretion of mucin from the HT29-MTX cell line","volume":"28","author":"Fergie","year":"2003","journal-title":"Clin. Otolaryngol. Allied Sci."},{"key":"10.1016\/j.micpath.2018.02.043_bib35","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/mus.21327","article-title":"Effects of prednisolone on skeletal muscle contractility in mdx mice","volume":"40","author":"Baltgalvis","year":"2009","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.micpath.2018.02.043_bib36","doi-asserted-by":"crossref","first-page":"5771","DOI":"10.1128\/IAI.68.10.5771-5777.2000","article-title":"Cellular and cytokine correlates of mucosal protection in murine model of oral candidiasis","volume":"68","author":"Elahi","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.02.043_bib37","first-page":"705","article-title":"Investigation of touch-sensitive responses by hyphae of the human pathogenic fungus Candida albicans","volume":"8","author":"Gow","year":"1994","journal-title":"Scanning Microsc."},{"key":"10.1016\/j.micpath.2018.02.043_bib38","doi-asserted-by":"crossref","first-page":"4216","DOI":"10.1128\/IAI.00559-12","article-title":"Dectin-1 is not required for controlling Candida albicans colonization of the gastrointestinal tract","volume":"80","author":"Vautier","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.02.043_bib39","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1038\/mi.2017.2","article-title":"The intraspecies diversity of C. albicans triggers qualitatively and temporally distinct host responses that determine the balance between commensalism and pathogenicity","volume":"10","author":"Schonherr","year":"2017","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.micpath.2018.02.043_bib40","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/ng.2710","article-title":"Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism","volume":"45","author":"Pande","year":"2013","journal-title":"Nat. Genet."},{"key":"10.1016\/j.micpath.2018.02.043_bib41","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01911-14","article-title":"Mucins suppress virulence traits of Candida albicans","volume":"5","author":"Kavanaugh","year":"2014","journal-title":"mBio"},{"key":"10.1016\/j.micpath.2018.02.043_bib42","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1128\/EC.00034-10","article-title":"Adaptations of Candida albicans for growth in the mammalian intestinal tract","volume":"9","author":"Rosenbach","year":"2010","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.micpath.2018.02.043_bib43","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/10454411940050020101","article-title":"Candida and oral candidosis: a review","volume":"5","author":"Scully","year":"1994","journal-title":"Crit. Rev. Oral Biol. Med."},{"key":"10.1016\/j.micpath.2018.02.043_bib44","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1086\/422329","article-title":"Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice","volume":"190","author":"Huang","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micpath.2018.02.043_bib45","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1002\/eji.200737409","article-title":"IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance","volume":"37","author":"Zelante","year":"2007","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.micpath.2018.02.043_bib46","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1007\/s10646-015-1540-7","article-title":"Metagenomic insights into tetracycline effects on microbial community and antibiotic resistance of mouse gut","volume":"24","author":"Yin","year":"2015","journal-title":"Ecotoxicology"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401017308781?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401017308781?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T07:21:41Z","timestamp":1693552901000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401017308781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":46,"alternative-id":["S0882401017308781"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2018.02.043","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gastrointestinal colonisation and systemic spread of Candida albicans in mice treated with antibiotics and prednisolone","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2018.02.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}