{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T23:31:28Z","timestamp":1791502288390,"version":"4.3.4"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100006143","name":"Department of Science and Technology, Government of Kerala","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006143","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.micpath.2018.04.041","type":"journal-article","created":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T04:33:43Z","timestamp":1524717223000},"page":"132-139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Cytomegalovirus aggravates the autoimmune phenomenon in systemic autoimmune diseases"],"prefix":"10.1016","volume":"120","author":[{"given":"Essam Mohammed Ahmed","family":"Janahi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shukla","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sambit Nath","family":"Bhattacharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shafiul","family":"Haque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naseem","family":"Akhter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshad","family":"Jawed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd","family":"Wahid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raju Kumar","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9414-4539","authenticated-orcid":false,"given":"Mohtashim","family":"Lohani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Yahya","family":"Areeshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishnampettai G.","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaia","family":"Almalki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2499-8701","authenticated-orcid":false,"given":"Sajad Ahmad","family":"Dar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2018.04.041_bib1","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.coi.2010.09.002","article-title":"Recent findings on genetics of systemic autoimmune diseases","volume":"22","author":"Delgado-Vega","year":"2010","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib2","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1007\/s00439-011-1137-z","article-title":"Unraveling the genetic component of systemic sclerosis","volume":"131","author":"Martin","year":"2012","journal-title":"Hum. Genet."},{"key":"10.1016\/j.micpath.2018.04.041_bib3","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1056\/NEJMra1100030","article-title":"Genomics and the multifactorial nature of human autoimmune disease","volume":"365","author":"Cho","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.micpath.2018.04.041_bib4","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/2042-4280-2-6","article-title":"Cytomegalovirus-induced immunopathology and its clinical consequences","volume":"2","author":"Varani","year":"2011","journal-title":"Herpesviridae"},{"key":"10.1016\/j.micpath.2018.04.041_bib5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1084\/jem.20070201","article-title":"Human CMV infection induces 5-lipoxygenase expression and leukotriene B4 production in vascular smooth muscle cells","volume":"205","author":"Qiu","year":"2008","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micpath.2018.04.041_bib6","doi-asserted-by":"crossref","first-page":"ra58","DOI":"10.1126\/scisignal.2001180","article-title":"HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis","volume":"3","author":"Slinger","year":"2010","journal-title":"Sci. Signal."},{"key":"10.1016\/j.micpath.2018.04.041_bib7","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1196\/annals.1422.059","article-title":"Epstein-Barr virus and cytomegalovirus in autoimmune diseases: are they truly notorious? A preliminary report","volume":"1108","author":"Barzilai","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.micpath.2018.04.041_bib8","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00430-007-0040-7","article-title":"Incidental discovery of high systemic lupus erythematosus disease activity associated with cytomegalovirus viral activity","volume":"196","author":"Su","year":"2007","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib9","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1038\/80533","article-title":"Systemic sclerosis immunoglobulin G autoantibodies bind the human cytomegalovirus late protein UL94 and induce apoptosis in human endothelial cells","volume":"6","author":"Lunardi","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.micpath.2018.04.041_bib10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2474-2-3","article-title":"MCMV induces neointima in IFN-gammaR-\/- mice: intimal cell apoptosis and persistent proliferation of myofibroblasts","volume":"2","author":"Hamamdzic","year":"2001","journal-title":"BMC Musculoskelet. Disord."},{"key":"10.1016\/j.micpath.2018.04.041_bib11","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1371\/journal.pmed.0030002","article-title":"Antibodies against human cytomegalovirus in the pathogenesis of systemic sclerosis: a gene array approach","volume":"3","author":"Lunardi","year":"2006","journal-title":"PLoS Med."},{"key":"10.1016\/j.micpath.2018.04.041_bib12","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/ar3525","article-title":"Autoimmunity induced by human cytomegalovirus in patients with systemic lupus erythematosus","volume":"14","author":"Soderberg-Naucler","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.micpath.2018.04.041_bib13","doi-asserted-by":"crossref","first-page":"8492","DOI":"10.1073\/pnas.86.21.8492","article-title":"Determination of an epitope of the diffuse systemic sclerosis marker antigen DNA topoisomerase I: sequence similarity with retroviral p30gag protein suggests a possible cause for autoimmunity in systemic sclerosis","volume":"86","author":"Maul","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.micpath.2018.04.041_bib14","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.hrtlng.2008.07.001","article-title":"Severe cytomegalovirus (CMV) community-acquired pneumonia (CAP) precipitating a systemic lupus erythematosus (SLE) flare","volume":"38","author":"Cunha","year":"2009","journal-title":"Heart Lung"},{"key":"10.1016\/j.micpath.2018.04.041_bib15","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.jaci.2010.09.031","article-title":"The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity","volume":"127","author":"Nahum","year":"2011","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib16","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1136\/ard.61.10.937","article-title":"Systemic sclerosis following human cytomegalovirus infection","volume":"61","author":"Ferri","year":"2002","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.micpath.2018.04.041_bib17","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.autrev.2010.09.010","article-title":"Do infections facilitate the emergence of systemic sclerosis?","volume":"10","author":"Grossman","year":"2011","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.micpath.2018.04.041_bib18","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1084\/jem.20050882","article-title":"Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects","volume":"202","author":"Sylwester","year":"2005","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micpath.2018.04.041_bib19","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.4049\/jimmunol.173.3.1834","article-title":"Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection","volume":"173","author":"van Leeuwen","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib20","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1182\/blood-2005-09-3682","article-title":"Expansion of CD94\/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts","volume":"107","author":"Guma","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.micpath.2018.04.041_bib21","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1002\/art.1780400928","article-title":"Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus","volume":"40","author":"Hochberg","year":"1997","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.micpath.2018.04.041_bib22","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1136\/annrheumdis-2013-204424","article-title":"2013 classification criteria for systemic sclerosis: an American college of rheumatology\/European league against rheumatism collaborative initiative","volume":"72","author":"van den Hoogen","year":"2013","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.micpath.2018.04.041_bib23","first-page":"77","article-title":"Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g","volume":"97","author":"Boyum","year":"1968","journal-title":"Scand. J. Clin. Lab. Invest. Suppl."},{"key":"10.1016\/j.micpath.2018.04.041_bib24","first-page":"405","article-title":"Human cytomegalovirus infection and systemic lupus erythematosus","volume":"15","author":"Rider","year":"1997","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.micpath.2018.04.041_bib25","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/1529-0131(199902)42:2<389::AID-ANR23>3.0.CO;2-P","article-title":"Increased serum levels of antibodies against human cytomegalovirus and prevalence of autoantibodies in systemic sclerosis","volume":"42","author":"Neidhart","year":"1999","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.micpath.2018.04.041_bib26","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1159\/000045391","article-title":"Correlation between cytomegalovirus infection and Raynaud's phenomenon in lupus nephritis","volume":"82","author":"Stratta","year":"1999","journal-title":"Nephron"},{"key":"10.1016\/j.micpath.2018.04.041_bib27","doi-asserted-by":"crossref","first-page":"R27","DOI":"10.1186\/ar2621","article-title":"Reduced IgG anti-small nuclear ribonucleoprotein autoantibody production in systemic lupus erythematosus patients with positive IgM anti-cytomegalovirus antibodies","volume":"11","author":"Palafox Sanchez","year":"2009","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.micpath.2018.04.041_bib28","first-page":"821","article-title":"Evidence of activation of 2 herpesviruses, Epstein-Barr virus and cytomegalovirus, in systemic sclerosis and normal skins","volume":"27","author":"Vaughan","year":"2000","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.micpath.2018.04.041_bib29","first-page":"S35","article-title":"Immunoglobulin GM genes and IgG antibodies to cytomegalovirus in patients with systemic sclerosis","volume":"22","author":"Pandey","year":"2004","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.micpath.2018.04.041_bib30","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/j.1749-6632.2009.04808.x","article-title":"The role of infections in the immunopathogensis of systemic sclerosis\u2013evidence from serological studies","volume":"1173","author":"Arnson","year":"2009","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.micpath.2018.04.041_bib31","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00296-010-1573-4","article-title":"Serologic response to Epstein-Barr virus antigens in patients with systemic lupus erythematosus: a controlled study","volume":"32","author":"Esen","year":"2012","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.micpath.2018.04.041_bib32","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1096\/fasebj.12.13.1255","article-title":"Molecular mimicry and immune-mediated diseases","volume":"12","author":"Oldstone","year":"1998","journal-title":"FASEB J"},{"key":"10.1016\/j.micpath.2018.04.041_bib33","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1084\/jem.188.9.1725","article-title":"In vivo survival of viral antigen-specific T cells that induce experimental autoimmune encephalomyelitis","volume":"188","author":"Ufret-Vincenty","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micpath.2018.04.041_bib34","doi-asserted-by":"crossref","first-page":"3988","DOI":"10.1073\/pnas.071050898","article-title":"Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase","volume":"98","author":"Hiemstra","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.micpath.2018.04.041_bib35","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.1073\/pnas.0337679100","article-title":"Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus","volume":"100","author":"Baechler","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.micpath.2018.04.041_bib36","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1093\/rheumatology\/kei244","article-title":"Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients","volume":"45","author":"Tan","year":"2006","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.micpath.2018.04.041_bib37","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1002\/art.23451","article-title":"Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma","volume":"58","author":"Duan","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.micpath.2018.04.041_bib38","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/art.27224","article-title":"Systemic sclerosis and lupus: points in an interferon-mediated continuum","volume":"62","author":"Assassi","year":"2010","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.micpath.2018.04.041_bib39","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0008-8749(92)90321-F","article-title":"The CD45RO (p180, UCHL1) marker: complexity of expression in peripheral blood","volume":"145","author":"Zola","year":"1992","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib40","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1002\/eji.1830181102","article-title":"Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: implications for differential CD45 expression in T cell memory formation","volume":"18","author":"Merkenschlager","year":"1988","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib41","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s002960000063","article-title":"Cytomegalovirus infection in systemic necrotizing vasculitis: causative agent or opportunistic infection?","volume":"20","author":"Meyer","year":"2000","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.micpath.2018.04.041_bib42","first-page":"559","article-title":"Cytomegalovirus infection in patients with systemic lupus erythematosus","volume":"20","author":"Sekigawa","year":"2002","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.micpath.2018.04.041_bib43","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1080\/08916930500285352","article-title":"Infections and SLE","volume":"38","author":"Zandman-Goddard","year":"2005","journal-title":"Autoimmunity"},{"key":"10.1016\/j.micpath.2018.04.041_bib44","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.humpath.2006.06.002","article-title":"Cytomegalovirus-associated cutaneous vasculopathy and scleroderma sans inclusion body change","volume":"38","author":"Magro","year":"2007","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.micpath.2018.04.041_bib45","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1586\/eci.11.28","article-title":"CD4+CD25+ regulatory T cells in systemic sclerosis and other rheumatic diseases","volume":"7","author":"Michels-van Amelsfort","year":"2011","journal-title":"Expet Rev. Clin. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib46","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1002\/art.38119","article-title":"The percentage of FoxP3+Helios+ Treg cells correlates positively with disease activity in systemic lupus erythematosus","volume":"65","author":"Golding","year":"2013","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.micpath.2018.04.041_bib47","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/eji.201344280","article-title":"Regulatory T cells in systemic lupus erythematosus","volume":"45","author":"Ohl","year":"2015","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib48","article-title":"Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction","volume":"8","author":"Liu","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2018.04.041_bib49","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.0300-9475.2004.01370.x","article-title":"Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus","volume":"59","author":"Liu","year":"2004","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib50","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0896-8411(03)00121-5","article-title":"Quantification of regulatory T cells in patients with systemic lupus erythematosus","volume":"21","author":"Crispin","year":"2003","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.micpath.2018.04.041_bib51","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/096120339600500209","article-title":"In vitro type-1 and type-2 cytokine production in systemic lupus erythematosus: lack of relationship with clinical disease activity","volume":"5","author":"Barcellini","year":"1996","journal-title":"Lupus"},{"key":"10.1016\/j.micpath.2018.04.041_bib52","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1084\/jem.174.4.791","article-title":"Antigen-driven bystander suppression after oral administration of antigens","volume":"174","author":"Miller","year":"1991","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micpath.2018.04.041_bib53","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/j.1365-2249.1990.tb05340.x","article-title":"Soluble interleukin-2 receptor, interleukin-2 and interleukin-4 in sera and supernatants from patients with progressive systemic sclerosis","volume":"81","author":"Famularo","year":"1990","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib54","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/00002281-199511000-00011","article-title":"Raynaud's phenomenon and the vascular disease in scleroderma","volume":"7","author":"Kahaleh","year":"1995","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1016\/j.micpath.2018.04.041_bib55","first-page":"291","article-title":"Peripheral blood mononuclear cells of patients with systemic sclerosis produce increased amounts of interleukin 6, but not transforming growth factor beta 1","volume":"23","author":"Giacomelli","year":"1996","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.micpath.2018.04.041_bib56","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S1081-1206(10)63052-9","article-title":"Interleukin-10: biology, role in inflammation and autoimmunity","volume":"79","author":"Lalani","year":"1997","journal-title":"Ann. Allergy Asthma Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib57","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1146\/annurev.immunol.19.1.683","article-title":"Interleukin-10 and the interleukin-10 receptor","volume":"19","author":"Moore","year":"2001","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib58","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/sj.gene.6364180","article-title":"Interleukin-10 genotypes are associated with systemic sclerosis and influence disease-associated autoimmune responses","volume":"6","author":"Hudson","year":"2005","journal-title":"Genes Immun."},{"key":"10.1016\/j.micpath.2018.04.041_bib59","doi-asserted-by":"crossref","first-page":"34604","DOI":"10.1038\/srep34604","article-title":"Clinical associations of IL-10 and IL-37 in systemic lupus erythematosus","volume":"6","author":"Godsell","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2018.04.041_bib60","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1073\/pnas.97.4.1695","article-title":"Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)","volume":"97","author":"Kotenko","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.micpath.2018.04.041_bib61","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.chom.2016.02.005","article-title":"A cytomegalovirus peptide-specific antibody alters natural killer cell homeostasis and is shared in several autoimmune diseases","volume":"19","author":"Liu","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.micpath.2018.04.041_bib62","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.chom.2016.02.017","article-title":"CMV and NK cells: an unhealthy tryst?","volume":"19","author":"Soderberg-Naucler","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.micpath.2018.04.041_bib63","doi-asserted-by":"crossref","first-page":"9078","DOI":"10.1128\/JVI.74.19.9078-9082.2000","article-title":"Human cytomegalovirus virions differentially incorporate viral and host cell RNA during the assembly process","volume":"74","author":"Greijer","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2018.04.041_bib64","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.clim.2007.12.010","article-title":"CD4+CD25+ regulatory T cells (TREG) in systemic lupus erythematosus (SLE) patients: the possible influence of treatment with corticosteroids","volume":"127","author":"Azab","year":"2008","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.micpath.2018.04.041_bib65","doi-asserted-by":"crossref","first-page":"863","DOI":"10.2217\/imt.10.69","article-title":"Immunotherapy of systemic sclerosis","volume":"2","author":"Manno","year":"2010","journal-title":"Immunotherapy"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401018304789?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401018304789?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:20:52Z","timestamp":1760109652000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401018304789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":65,"alternative-id":["S0882401018304789"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2018.04.041","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cytomegalovirus aggravates the autoimmune phenomenon in systemic autoimmune diseases","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2018.04.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}