{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T09:46:53Z","timestamp":1770284813063,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100005421","name":"Guilan University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005421","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.micpath.2018.07.042","type":"journal-article","created":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T16:36:48Z","timestamp":1533055008000},"page":"426-432","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Evaluation of the immune responses following co-administration of PilQ and type b-flagellin from Pseudomonas aeruginosa in the burn mouse model"],"prefix":"10.1016","volume":"123","author":[{"given":"Sima","family":"Bakht azad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iraj","family":"Nikokar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4611-9985","authenticated-orcid":false,"given":"Sobhan","family":"Faezi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soheila","family":"Rasooly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Mahdavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2018.07.042_bib1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1128\/CVI.00669-13","article-title":"Flagellin a toll-like receptor 5 agonist as an adjuvant in chicken vaccines","volume":"21","author":"Gupta","year":"2014","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.micpath.2018.07.042_bib2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1128\/CMR.19.2.403-434.2006","article-title":"Burn wound infections","volume":"19","author":"Church","year":"2006","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.micpath.2018.07.042_bib3","doi-asserted-by":"crossref","first-page":"10706","DOI":"10.1002\/anie.201209979","article-title":"Combating multidrug\u2010resistant bacteria: current strategies for the discovery of novel antibacterials","volume":"52","author":"O'Connell","year":"2013","journal-title":"Angew Chem. Int. Ed. Engl."},{"key":"10.1016\/j.micpath.2018.07.042_bib4","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1016\/j.str.2016.08.007","article-title":"Structure of the Pseudomonas aeruginosa type IVa pilus secretin at 7.4 A","volume":"24","author":"Koo","year":"2016","journal-title":"Structure"},{"key":"10.1016\/j.micpath.2018.07.042_bib5","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1084\/jem.134.4.886","article-title":"Studies on gonococcus infection I. Pili and zones of adhesion: their relation to gonococcal growth patterns","volume":"134","author":"Swanson","year":"1971","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micpath.2018.07.042_bib6","doi-asserted-by":"crossref","first-page":"5434","DOI":"10.1128\/IAI.00411-07","article-title":"Additive and synergistic bactericidal activity of antibodies directed against minor outer membrane proteins of Neisseria meningitidis","volume":"75","author":"Weynants","year":"2007","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.07.042_bib7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1146\/annurev.micro.55.1.49","article-title":"Bacterial gliding motility: multiple mechanisms for cell movement over surfaces","volume":"55","author":"McBride","year":"2001","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.micpath.2018.07.042_bib8","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1128\/JB.185.8.2611-2617.2003","article-title":"Three-dimensional structure of the Neisseria meningitidis secretin PilQ determined from negative-stain transmission electron microscopy","volume":"185","author":"Collins","year":"2003","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2018.07.042_bib9","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/j.1365-2958.2008.06197.x","article-title":"Type IV pili: e pluribus unum?","volume":"68","author":"Pelicic","year":"2008","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micpath.2018.07.042_bib10","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1159\/000077869","article-title":"Pulling together with type IV pili","volume":"7","author":"Nudleman","year":"2004","journal-title":"J. Mol. Microbiol. Biotechnol."},{"key":"10.1016\/j.micpath.2018.07.042_bib11","doi-asserted-by":"crossref","first-page":"B42","DOI":"10.1016\/j.vaccine.2009.05.001","article-title":"Meningococcal protein antigens and vaccines","volume":"27","author":"Feavers","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.micpath.2018.07.042_bib12","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S1286-4579(00)01259-4","article-title":"Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist","volume":"2","author":"Lyczak","year":"2000","journal-title":"Microb. Infect."},{"key":"10.1016\/j.micpath.2018.07.042_bib13","first-page":"37","article-title":"High yield overexpression, refolding, purification and characterization of Pseudomonas aeruginosa type B-Flagellin: an improved method without sonication","volume":"5","author":"Faezi","year":"2016","journal-title":"Int. J. Mol. Cell. Med."},{"key":"10.1016\/j.micpath.2018.07.042_bib14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.biologicals.2017.04.001","article-title":"Preparation of Pseudomonas aeruginosa alginate-flagellin immunoconjugate","volume":"47","author":"Faezi","year":"2017","journal-title":"Biologicals"},{"key":"10.1016\/j.micpath.2018.07.042_bib15","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1099\/jmm.0.000174","article-title":"Pseudomonas aeruginosa flagellin as an adjuvant: superiority of a conjugated form of flagellin versus a mixture with a human immunodeficiency virus type 1 vaccine candidate in the induction of immune responses","volume":"64","author":"Delavari","year":"2015","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.micpath.2018.07.042_bib16","doi-asserted-by":"crossref","first-page":"5677","DOI":"10.4049\/jimmunol.1002156","article-title":"Flagellin as an adjuvant: cellular mechanisms and potential","volume":"185","author":"Mizel","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2018.07.042_bib17","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1128\/IAI.49.3.770-774.1985","article-title":"Electrophoretic separation and molecular weight characterization of Pseudomonas aeruginosa H-antigen flagellins","volume":"49","author":"Allison","year":"1985","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.07.042_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2015.00169","article-title":"Incorporation of membrane-anchored flagellin or Escherichia coli heat-labile enterotoxin B subunit enhances the immunogenicity of rabies virus-like particles in mice and dogs","volume":"6","author":"Qi","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2018.07.042_bib19","doi-asserted-by":"crossref","first-page":"5998","DOI":"10.4049\/jimmunol.164.11.5998","article-title":"Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells","volume":"164","author":"Muzio","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2018.07.042_bib20","doi-asserted-by":"crossref","first-page":"7010","DOI":"10.1128\/IAI.68.12.7010-7017.2000","article-title":"Differential alteration in intestinal epithelial cell expression of toll-like receptor 3) TLR3) and TLR4 in inflammatory bowel disease","volume":"68","author":"Cario","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.07.042_bib21","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1038\/35074106","article-title":"The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5","volume":"410","author":"Hayashi","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.micpath.2018.07.042_bib22","first-page":"10","article-title":"Comparison between active and passive immunization with flagellin-based subunit vaccine from Pseudomonas aeruginosa in the burned-mouse model","volume":"7","author":"Faezi","year":"2013","journal-title":"Iran. J. Clin. Infect. Dis."},{"key":"10.1016\/j.micpath.2018.07.042_bib23","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1128\/IAI.00157-11","article-title":"Efficacy of a conjugate vaccine containing polymannuronic acid and flagellin against experimental Pseudomonas aeruginosa lung infection in mice","volume":"79","author":"Campodonico","year":"2011","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.07.042_bib24","first-page":"34","article-title":"Molecular characterization and functional analysis of the PilQ380-706: a novel secretin domain in Pseudomonas aeruginosa","volume":"10","author":"Faezi","year":"2018","journal-title":"Avicenna J. Med. Biotechnol. (AJMB)"},{"key":"10.1016\/j.micpath.2018.07.042_bib25","doi-asserted-by":"crossref","first-page":"5908","DOI":"10.1128\/IAI.69.9.5908-5910.2001","article-title":"PcrV immunization enhances survival of burned Pseudomonas aeruginosa-infected mice","volume":"69","author":"Holder","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.07.042_bib26","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.micinf.2015.01.004","article-title":"How bacterial pathogens colonize their hosts and invade deeper tissues","volume":"17","author":"Ribet","year":"2015","journal-title":"Microb. Infect."},{"key":"10.1016\/j.micpath.2018.07.042_bib27","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.ijmm.2017.07.004","article-title":"Relevance of multidrug-resistant Pseudomonas aeruginosa infections in cystic fibrosis","volume":"307","author":"Stefani","year":"2017","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.micpath.2018.07.042_bib28","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.burns.2008.08.014","article-title":"Therapy with anti-flagellin A monoclonal antibody limits Pseudomonas aeruginosa invasiveness in a mouse burn wound sepsis model","volume":"35","author":"Barnea","year":"2009","journal-title":"Burns"},{"key":"10.1016\/j.micpath.2018.07.042_bib29","first-page":"458","article-title":"Construction, expression, purification and characterization of secretin domain of PilQ and triple PilA-related disulfide loop peptides fusion protein from Pseudomonas aeruginosa","volume":"20","author":"Faezi","year":"2017","journal-title":"Iran. J. Basic. Med. Sci."},{"key":"10.1016\/j.micpath.2018.07.042_bib30","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/j.vaccine.2016.01.041","article-title":"Induction of humoral immune response against Pseudomonas aeruginosa flagellin(1-161) using gold nanoparticles as an adjuvant","volume":"34","author":"Dakterzada","year":"2016","journal-title":"Vaccine"},{"key":"10.1016\/j.micpath.2018.07.042_bib31","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1128\/IAI.72.5.2810-2816.2004","article-title":"Flagellin fusion proteins as adjuvants or vaccines induce specific immune responses","volume":"72","author":"Cuadros","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2018.07.042_bib32","first-page":"017","article-title":"Protective efficacy of the trivalent Pseudomonas aeruginosa vaccine candidate PcrV-OprI-Hcp1 in Murine pneumonia and burn models","volume":"7","author":"Yang","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2018.07.042_bib33","doi-asserted-by":"crossref","first-page":"4965","DOI":"10.4049\/jimmunol.181.7.4965","article-title":"IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strains of Pseudomonas aeruginosa","volume":"181","author":"Priebe","year":"2008","journal-title":"J. Immunol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401017317965?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401017317965?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,7]],"date-time":"2020-11-07T02:44:47Z","timestamp":1604717087000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401017317965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":33,"alternative-id":["S0882401017317965"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2018.07.042","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of the immune responses following co-administration of PilQ and type b-flagellin from Pseudomonas aeruginosa in the burn mouse model","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2018.07.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}